Research to Prevent Blindness

RPB and OCT Research

In addition to Dr. Wang’s work, RPB has funded many important OCT-related research projects since 2004: 

  • Correlation of specific gene mutation in Stargardt’s disease with OCT-identified structural features of the retina-Columbia University College of Physicians & Surgeons
  • Anatomic appearance in OCT of the normal macula, the part of the retina involved in sharp, central vision-University of Miami School of Medicine
  • OCT imaging of the mouse and rat retina in studies of glaucoma gene therapy-University of North Carolina at Chapel Hill School of Medicine
  • Hand-held OCT for studying the structural appearance of the retina in premature and normal infants-University of North Carolina at Chapel Hill School of Medicine and also Duke University School of Medicine
  • OCT studies of blood vessel density and mapping in the retina of patients with age-related macular degeneration-Northwestern University Feinberg School of Medicine
  • OCT imaging of corneal cells for improving stem cell therapy for treatment of corneal damage and disease-University of Pittsburgh School of Medicine
  • Detection of recovery, using OCT, of normal retinal structure following injections beneath the retina for delivery of experimental treatments;-University of Wisconsin-Madison School of Medicine
  • OCT comparison of retinal structure in animals and humans with similar gene-related retinal disease-University of Texas Medical Branch, Galveston
  • Structural assessment, using OCT, of the anterior chamber angle in glaucoma and software development to analyze the anterior angle and related structures before and after treatment-University of Texas Health Science Center at Houston
  • Development of statistical software for analyzing OCT images of holes and cysts of the macula-Cleveland Clinic Lerner College of medicine of CWRU
  • OCT analysis of anatomic changes in the optic nerve head in normal and patients with glaucoma during normal and high intraocular pressure conditions-Duke University school of Medicine
  • OCT identification of structural changes in photoreceptor cells of patients undergoing anti-VEGF therapy for age-related macular degeneration. (Anti-VEGF therapy refers to a treatment for halting the growth of troublesome blood vessels beneath the retina-University of Illinois-Chicago/Illinois Eye and Ear Infirmary
  • OCT-based mapping of the cornea for a better understanding of keratoconus diagnosis and progression-Cleveland Clinic Lerner School of Medicine
  • OCT identification of early structural changes in the retina of patients with diabetes for helping patients maintain good vision-University of Michigan School of Medicine
  • OCT studies to identify anatomic features of the retina for predicting the patients with AMD who are likely to progress to more serious AMD and who may benefit from increased monitoring or treatment at an earlier stage-Keck School of Medicine of the University of Southern California


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