Grants Database
Research to Prevent Blindness (RPB) provides grants to high-performing U.S.-based departments of ophthalmology and to their high-potential investigators. Use our Grants Database to learn more. Award amounts for some grants are distributed over multiple years.
How to use the Grants Database
Refine your search by using the filter at left. Search by setting a date range, or filter your results by institution, research area keyword, or awardee. Sort the table by clicking on any column header.
Learn about an institution or individual by clicking on a name.
Learn about RPB-supported work by clicking on the text link "Research funded by this award," which will take you to our Research Database where you can refine and/or expand a search for published studies. (Note: In some cases this link will not be available because a researcher may have only recently received an award and has yet to publish findings.)
RPB Grant Awards from 2016 & 2017
83 Awards ($13,792,295)
| RPB Grant Type |
Year |
Award |
Research Area |
Awardee |
Institution |
| Career Development Award | 2017 | $300,000 | Ocular Oncology, Pathology, Retina | Afshar, Armin / MD, MBA | University of California, San Francisco, School of Medicine |
| Will undertake research to improve our understanding of the patient prognosis of uveal melanoma, a devastating ocular cancer, including outcomes related to the eye, quality of life and survival after radiotherapy. | |||||
| Career Development Award | 2017 | $300,000 | Retina | Byrne, Leah / PhD | University of Pittsburgh School of Medicine |
| Proposes to create a flexible method of gene and protein delivery in the retina, where gene therapy represents a highly promising approach to treating retinal diseases, through a modular system of small viruses. | |||||
| Career Development Award | 2017 | $300,000 | Imaging, Retina | Chen, Xi / MD, PhD | Duke University School of Medicine |
| Proposes to utilize a noninvasive advanced imaging technique to visualize, in real-time, the development of blood vessels in the retina in human infants. | |||||
| Career Development Award | 2017 | $300,000 | Glaucoma, Pharmacology, Physiology | Pitha, Ian / MD, PhD | Johns Hopkins University School of Medicine |
| Will investigate a cellular process that could lead to a new therapeutic target (in the form of manipulation of peripapillary scleral fibroblast activity) for neuroprotection from glaucoma-related retinal ganglion cell death and vision loss. | |||||
| Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration | 2017 | $300,000 | AMD, Retina | Bowes Rickman, Catherine / PhD | Duke University School of Medicine |
| Proposes to use unique and relevant models of chronic, dry AMD to test three therapeutic approaches that will shape strategies for targeting the complement pathway versus targeting cholesterol versus a combined therapeutic approach targeting both pathways. | |||||
| Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration | 2017 | $300,000 | AMD, Retina | Green, Jordan / PhD | Johns Hopkins University School of Medicine |
| Proposes to develop a breakthrough translational therapy for neovascular (wet) AMD, as well as a biodegradable drug delivery system that would allow sustained, 6-month release. | |||||
| Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration | 2017 | $300,000 | AMD, Retina | Sinha, Debasish / PhD | University of Pittsburgh School of Medicine |
| Will develop a treatment for early, dry AMD that works by rejuvenating impaired lysosomal function. | |||||
| Medical Student Eye Research Fellowship | 2017 | $30,000 | Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus, Visual Neuroscience | Asanad, Samuel | David Geffen School of Medicine at the University of California, Los Angeles |
| Conducting research at David Geffen School of Medicine, University of California, Los Angeles. | |||||
| Medical Student Eye Research Fellowship | 2017 | $30,000 | Immunology, Microbiology | Heisel, Curtis | The Regents of the University of Michigan School of Medicine |
| Conducting research at the The Regents of the University of Michigan School of Medicine. | |||||
| Medical Student Eye Research Fellowship | 2017 | $30,000 | Biochemistry, Molecular Biology, Pharmacology, Physiology, Retina, Retinal Cell Biology | Jauregui, Ruben | Columbia University College of Physicians & Surgeons |
| Conducting research at Columbia University College of Physicians & Surgeons. | |||||
| Physician-Scientist Award | 2017 | $300,000 | Glaucoma | Samuels, Brian / MD, PhD | University of Alabama at Birmingham School of Medicine |
| Will investigate optic nerve biomechanics in the tree shrew, a potential new, economical animal model for glaucoma, which overcomes many of the biological barriers found in current animal models. | |||||
| Physician-Scientist Award | 2017 | $300,000 | Retinal Cell Biology | Sears, Jonathan Eliot / MD | Cleveland Clinic Lerner College of Medicine of CWRU |
| Proposes to explore the ability of liver stimulation (via hypoxia-inducible factor stabilization) to protect blood vessels in the eye for infants with retinopathy of prematurity (ROP), a major cause of childhood blindness. | |||||
| RPB/SNF International Research Collaborators Award | 2017 | $75,000 | Anatomy, Ocular Oncology, Pathology | Cobrinik, David / MD, PhD | Keck School of Medicine of the University of Southern California |
| Proposes to determine how rod-derived cone viability factor (RdCVF) expression is regulated in developing cone photoreceptors, both to enable ways to suppress RdCVF in retinoblastoma (an ocular cancer most common in childhood) and to develop approaches to sustain RdCVF expression in patients with retinal degenerations. | |||||
| Special Grant | 2017 | $34,000 | The Heed Ophthalmic Foundation | ||
| Residents Retreat, 2017 and 2018. Encourage and facilitate talented residents to pursue a career in academic ophthalmology. | |||||
| Stein Innovation Award | 2017 | $300,000 | Cell Biology, Genetics, Retinal Cell Biology, Systems Biology | Katsanis, Nicholas / PhD | Duke University School of Medicine |
| Proposes to test a new therapeutic target (which consists of suppressing gene USP35) for retinal degenerative diseases, such as retinitis pigmentosa (RP), using cell-based screens in zebrafish. | |||||
| Stein Innovation Award | 2017 | $300,000 | Anatomy, Cell Biology, Glaucoma, Ocular Oncology, Pathology, Pharmacology, Physiology, Retinal Cell Biology | Nedergaard, Maiken / MD, DMSc | University of Rochester School of Medicine & Dentistry |
| Will characterize the biology and ocular physiology of the glymphatic system, a recently discovered macroscopic waste clearance system for the central nervous system that is required for normal brain function, but also has a critical role in neurodegenerative disease. | |||||
| Stein Innovation Award | 2017 | $300,000 | Genetics, Systems Biology | Neuringer, Martha / PhD | Oregon Health & Science University School of Medicine |
| Will utilize new genetic technology to create monkey models of human-like retinal degenerative diseases, such as achromatopsia, a disabling disease affecting daylight vision, visual acuity and color vision. | |||||
| Stein Innovation Award | 2017 | $300,000 | Pharmacology, Physiology | Semenza, Gregg L. / MD, PhD | Johns Hopkins University School of Medicine |
| Proposes to treat excessive blood vessel grown (as seen in age-related macular degeneration and diabetic macular edema) by developing more potent and specific small molecule hypoxia-inducible factor (HIF) inhibitors in long-lasting formulations. | |||||
| Stein Professorship/Extension | 2017 | $250,000 | Retinal Cell Biology | Perkins, Brian / PhD | Cleveland Clinic Lerner College of Medicine of CWRU |
| Will use zebrafish research to identify the contribution of specific micro-ribonucleic acids (mi-RNAs)—building blocks of life that help to code, regulate and express genes—to photoreceptor survival, as well as provide a unique collection of mutant zebrafish that can be used to determine the role of each mi-RNA in regulating cellular pathways. | |||||
| Disney Award for Amblyopia Research | 2017 | $100,000 | Amblyopia, Eye Movements, Neuro-Ophthalmology, Pharmacology, Physiology, Strabismus, Visual Neuroscience | Aton, Sara / PhD | The Regents of the University of Michigan School of Medicine |
| Investigating the role of sleep in modifying plasticity of the visual system, based on results of previous research. | |||||
| Career Development Award | 2017 | $300,000 | Biochemistry, Molecular Biology, Pharmacology, Physiology, Retina, Retinal Cell Biology, Visual Neuroscience | Duan, Xin / PhD | University of California, San Francisco, School of Medicine |
| Gain a deep understanding of optic nerve regeneration via synapse formation and neural circuit mapping. | |||||
| Career Development Award | 2017 | $300,000 | Immunology, Microbiology | Pepple, Kathryn L. / MD, PhD | University of Washington School of Medicine |
| Developing an unbiased, non-invasive, quantitative, in vivo assay for uveitis, using bioluminescence. | |||||
| Low Vision Research Award | 2017 | $300,000 | Low Vision | Gardner, Justin / PhD | Stanford University School of Medicine |
| Measuring and tracking visual and auditory sensory performance following sight-restoring surgery, such as cataract removal or corneal replacement, for adult humans. | |||||
| Low Vision Research Award | 2017 | $100,000 | Low Vision | Luo, Gang / PhD | Harvard Medical School |
| Designing a mobile application to perform keyword searches in real-world environments to enhance the visual search capabilities of persons with low vision. | |||||
| Medical Student Eye Research Fellowship | 2017 | $30,000 | Clinical, Epidemiologic | Liu, Tianyu | University of Pennsylvania School of Medicine |
| Conducting research at the University of Pennsylvania School of Medicine. | |||||
| Medical Student Eye Research Fellowship | 2017 | $30,000 | Clinical, Optic Neuropathy | Udeh, Adanna | University of Miami Miller School of Medicine |
| Conducting research at the University of Miami Miller School of Medicine. | |||||
| RPB/SNF International Research Collaborators Award | 2017 | $75,000 | Glaucoma, Retina, Retinal Cell Biology | Mandal, Nawajes / PhD | University of Tennessee Health Science Center |
| Testing whether anti-ceramide gene therapy, delivered through a specific model, will be protective in four different animal models of retinal degeneration. | |||||
| Special Grant | 2017 | $165,000 | Association of University Professors of Ophthalmology | ||
| AUPO is a key ally in RPB's commitment to enrich the development of the Chairs, Directors of Research, and other leaders from departments of ophthalmology. | |||||
| Special Grant | 2017 | $55,000 | Drug Delivery | Ensign, Laura / PhD | Johns Hopkins University School of Medicine |
| Investigating delivery of drug microcrystals to the suprachoroidal space, thereby avoiding potential complications with intravitreal injections. | |||||
| Special Scholar Award | 2017 | $25,000 | Biochemistry, Molecular Biology, Retina, Retinal Cell Biology | Chen, Jing / PhD | Harvard Medical School |
| Investigating the role of a novel redox (reduction/oxidation) sensitive nuclear receptor in mediating oxidative stress-dependent RPE (retinal pigment epithelium) and retinal dysfunction, which contributes to the pathogenesis of age-related macular degeneration (AMD). | |||||
| Special Scholar Award | 2017 | $55,000 | Drug Delivery | Ensign, Laura / PhD | Johns Hopkins University School of Medicine |
| Investigating delivery of drug microcrystals to the suprachoroidal space, thereby avoiding potential complications with intravitreal injections. | |||||
| Special Scholar Award | 2017 | $75,000 | Retina | Hunter, Jennifer J. / PhD | University of Rochester School of Medicine & Dentistry |
| Establishing a research program in 2-photon fluorescence imaging of the retina using an adaptive optics scanning light ophthalmoscope (AOSLO). Also proposing to add fluorescent lifetime imaging (FLIM) capability to an AOSLO, thereby allowing measurement of lipofuscin composition in retinal pigment epithelial cells, which is relevant to age-related macula degeneration, Stargardt disease, and other macular diseases. | |||||
| Special Scholar Award | 2017 | $60,000 | Imaging, Retina | Jia, Yali / PhD | Oregon Health & Science University School of Medicine |
| Developing wide-field and projection-resolved optical coherence tomography angiography (OCTA) and apply them to the diagnosis and evaluation of inherited retinal diseases. | |||||
| Stein Innovation Award | 2017 | $300,000 | Cornea | Funderburgh, James L. / PhD | University of Pittsburgh School of Medicine |
| Define roles for stem cell-derived extracellular vesicles and the mechanism by which they induce corneal regeneration and explore the potential to replace therapy involving live stem cells with a defined mixture of bio-molecules. | |||||
| Stein Innovation Award | 2017 | $300,000 | Anatomy, Biochemistry, Cell Biology, Molecular Biology, Ocular Oncology, Pathology, Pharmacology, Physiology, Retina, Retinal Cell Biology | Sheibani, Nader / PhD | University of Wisconsin-Madison School of Medicine & Public Health |
| Investigating the role of mitochondrial carbonic anhydrase and its inhibition on pericytes loss. | |||||
| Career Development Award | 2016 | $300,000 | Biochemistry, Molecular Biology, Retina | Rajagopal, Rithwick / MD, PhD | Washington University in Saint Louis School of Medicine |
| Will use animal models of diabetic eye disease to learn how fenofibrate, a drug clinically-approved to treat cholesterol, protects the eye from diabetes-related damage, as well as identify alternative therapeutic pathways that have fewer serious side effects. | |||||
| Career Development Award | 2016 | $300,000 | Physiological Optics, Visual Psychophysics | Sabesan, Ramkumar / PhD | University of Washington School of Medicine |
| Proposes to develop a specialized camera to capture how the retina’s rods and cones (responsible for turning light energy into shapes and colors) work in health and how they fail in diseases. | |||||
| Medical Student Eye Research Fellowship | 2016 | $30,000 | Retina | Sears, Connie M. | David Geffen School of Medicine at the University of California, Los Angeles |
| Conducting research at the University of California, Los Angeles. | |||||
| Medical Student Eye Research Fellowship | 2016 | $30,000 | Retinal Cell Biology | Vo, Thomas | University of California, Irvine, School of Medicine |
| Conducting research at the University of California, Irvine, School of Medicine. | |||||
| Nelson Trust Award for Retinitis Pigmentosa | 2016 | $50,000 | Retina | Apte, Rajendra S. / MD, PhD | Washington University in Saint Louis School of Medicine |
| Proposes to investigate whether a specific cause of metabolic dysfunction plays a role in photoreceptor and vision loss across types of retinitis pigmentosa. | |||||
| Nelson Trust Award for Retinitis Pigmentosa | 2016 | $100,000 | Retina | Vandenberghe, Luk H. / PhD | Harvard Medical School |
| Proposes to create a method for safe and efficient gene transfer (a proven treatment for retinitis pigmentosa) to the retina via an intravitreal route of injection, thereby avoiding the issues associated with the current and more invasive standard, subretinal injection. | |||||
| RPB/SNF International Research Collaborators Award | 2016 | $75,000 | Amblyopia, Eye Movements, Neuro-Ophthalmology, Pharmacology, Physiological Optics, Physiology, Strabismus, Visual Neuroscience, Visual Psychophysics | Kohn, Adam / PhD | Albert Einstein College of Medicine |
| Propose a collaborative effort to discover how feedback signals change the activity of nerve cells in the visual cortex, and therefore how they might influence our capacity to see. | |||||
| Stein Innovation Award | 2016 | $300,000 | Immunology, Microbiology | Britton, Robert / PhD | Baylor College of Medicine |
| Will explore the mechanisms by which intestinal tract bacteria impact the health of the eye, as well as identify specific bacteria that can be used therapeutically for dry eye and/or uveitis. | |||||
| Stein Innovation Award | 2016 | $300,000 | Glaucoma | Jiang, Hongrui / PhD, MS | University of Wisconsin-Madison School of Medicine & Public Health |
| Will develop micro-scale devices to measure real-time pressure at the optic nerve head and choroidal tension during accommodation—two processes thought to be potentially responsible for damage related to glaucoma. | |||||
| Stein Innovation Award | 2016 | $300,000 | Pharmacology, Physiology | Malik, Asrar B. / PhD | University of Illinois at Chicago College of Medicine |
| Proposes to address mechanisms regulating the overgrowth of retinal blood vessels in age-related macular degeneration (AMD) using eye drops instead of injections. | |||||
| Career Development Award | 2016 | $300,000 | Anatomy, Ocular Oncology, Pathology | Daniels, Anthony Brent / MD, MSc | Vanderbilt University School of Medicine |
| Seeking less toxic chemotherapeutic alternatives to currently-used regimens in the treatment of retinoblastoma (an eye cancer that develops in babies) in a rabbit model. | |||||
| Career Development Award | 2016 | $300,000 | Immunology, Microbiology | Doan, Thuy A. / MD, PhD | University of California, San Francisco, School of Medicine |
| Will use next-generation sequencing to comprehensively assess bacteria and viruses on and in the eye in normal health and disease and during treatment with antibiotics. | |||||
| Career Development Award | 2016 | $300,000 | Glaucoma | Newman-Casey, Paula Anne / MD | The Regents of the University of Michigan School of Medicine |
| Seeking to optimize implementation of behavioral interventions into current clinical operations in the treatment of glaucoma, with the goal of increasing medication adherence. | |||||
| Disney Award for Amblyopia Research | 2016 | $100,000 | Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus | Kiorpes, Lynne / PhD | New York University School of Medicine |
| Will use psychophysical paradigms (stimulus-perception techniques) to explore attentional deficits in amblyopic children and to develop strategies that will improve not only visual acuity but also non-visual acuity perceptual deficits in amblyopia treatment. | |||||
| Disney Award for Amblyopia Research | 2016 | $100,000 | Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus | McGee, Aaron W. / PhD | University of Louisville School of Medicine |
| Seeks to establish optimal, gene-inhibiting, drug intervention targets in the development of the visual pathway (in mice) in order to prolong the period of visual plasticity in the visual system – a sensitive period which is related to amblyopia in humans. | |||||
| International Research Scholar Award | 2016 | $1,295 | Biochemistry, Cornea, Immunology, Microbiology | Schenke-Layland, Katja / PhD, MSc | Keck School of Medicine of the University of Southern California |
|
Develop a novel stem cell-based tissue engineering strategy to regenerate lacrimal glands that are damaged by the autoimmune inflammation associated with Sjögren’s syndrome. |
|||||
| Low Vision Research Award | 2016 | $100,000 | Manduchi, Roberto / PhD | University of California, Santa Cruz | |
| Developing an economical and easy-to-use low vision screen magnifier that will enable scrolling control by means of the viewer’s own gaze, rather than using a mouse or trackpad. | |||||
| Low Vision Research Award | 2016 | $300,000 | Merabet, Lotfi B. / OD, PhD, MPH | Harvard Medical School | |
| Seeking to establish linkages between observed perceptual deficits and the underlying neurophysiology in cortical visual impairment (CVI), a leading cause of pediatric low vision. | |||||
| Medical Student Eye Research Fellowship | 2016 | $30,000 | Retina | Gupta, Priya Rani | Harvard Medical School |
| Conducting research at Harvard Medical School / MEEI. | |||||
| Medical Student Eye Research Fellowship | 2016 | $30,000 | Biochemistry, Pharmacology, Physiology, Retina, Retinal Cell Biology | Sengillo, Jesse D. | Columbia University College of Physicians & Surgeons |
| Conducting research at Columbia University College of Physicians & Surgeons. | |||||
| Physician-Scientist Award | 2016 | $300,000 | Cornea | Chan, Matilda F. / MD, PhD | University of California, San Francisco, School of Medicine |
| Investigating the hypothesis that a specific form of DNA modification—DNA methylation—plays a significant role in the development of Fuchs Endothelial Corneal Dystrophy (FECD); testing an FDA-approved drug that is able to reverse DNA methylation in cancer cells to reverse it also in the cornea. | |||||
| Physician-Scientist Award | 2016 | $300,000 | Retina | Sun, Jennifer K. / MD, MPH | Harvard Medical School |
| Using noninvasive optical coherence tomography angiography to establish changes in the retinal capillary network as biomarkers that predict retinal neural damage leading to vision loss or the worsening of diabetic retinopathy over time. | |||||
| Special Grant | 2016 | $125,000 | Association of University Professors of Ophthalmology | ||
| AUPO is a key ally in RPB's commitment to enrich the development of the Chairs, Directors of Research, and other leaders from departments of ophthalmology. | |||||
| Special Scholar Award | 2016 | $75,000 | Retina | Lad, Eleonora / MD, PhD | Duke University School of Medicine |
| Understanding the role of monocytes (type of white blood cell) in dry AMD in order to support the concept that monocytes should be investigated as therapeutic targets for treatment of dry AMD. | |||||
| Special Scholar Award | 2016 | $25,000 | Physiological Optics, Visual Psychophysics | McAnany, J. Jason / PhD | University of Illinois at Chicago College of Medicine |
| Developing a “multi-modal functional assay” for complete characterization of early neural changes in patients with diabetic retinopathy (DR), with the goal of early detection and diagnosis in at-risk populations. | |||||
| Special Scholar Award | 2016 | $55,000 | Retina, Retinal Cell Biology | McGill, Trevor / PhD | Oregon Health & Science University School of Medicine |
| Developing a novel contrast agent and cell viability marker for use with optical coherence tomography to document the survival, migration, and integration of transplanted, therapeutic stem cells in the treatment of retinal degenerative diseases. | |||||
| Special Scholar Award | 2016 | $60,000 | Pharmacology, Physiology, Retina, Visual Neuroscience | Wong, Kwoon Y. / PhD | The Regents of the University of Michigan School of Medicine |
| Seeking to learn how intrinsically photosensitive retinal ganglion cells (ipRGCs) respond to light and interact with other retinal cells in order to potentially improve the visual capability of blind and low-vision patients. | |||||
| Stein Innovation Award | 2016 | $300,000 | Pharmacology, Physiology | Puro, Donald G. / MD, PhD | The Regents of the University of Michigan School of Medicine |
| Exploring the role of ion channels in the response of tear-film-stabilizing goblet cells to changes in the salt content of tears as a potentially new avenue to develop more effective therapeutic strategies to combat dry eye. | |||||
| Stein Innovation Award | 2016 | $300,000 | Retina | Schwartz, Daniel M. / MD | University of California, San Francisco, School of Medicine |
| Developing and testing a novel light-activated drug that potentially can arrest progressive ocular growth and macular stretching that occurs in degenerative myopia. | |||||
| Stein Innovation Award | 2016 | $300,000 | Cell Biology, Retina, Retinal Cell Biology | Sung, Ching-Hwa / PhD | Weill Cornell Medical College |
| Testing the hypothesis that manipulating signals to structures on the surface of cultured retinal progenitor cells can generate specific types of retinal neurons essential to cell replacement therapy for damaged retinas. | |||||
| Departmental Grant | 2016 | $115,000 | Cleveland Clinic Lerner College of Medicine of CWRU | ||
| Departmental Grant | 2016 | $115,000 | Emory University School of Medicine | ||
| Departmental Grant | 2016 | $115,000 | Harvard Medical School | ||
| Departmental Grant | 2016 | $115,000 | Indiana University School of Medicine | ||
| Departmental Grant | 2016 | $115,000 | Johns Hopkins University School of Medicine | ||
| Departmental Grant | 2016 | $115,000 | Keck School of Medicine of the University of Southern California | ||
| Departmental Grant | 2016 | $115,000 | Louisiana State University Health Sciences Center in New Orleans | ||
| Departmental Grant | 2016 | $115,000 | Mayo Clinic, College of Medicine | ||
| Departmental Grant | 2016 | $115,000 | Oregon Health & Science University School of Medicine | ||
| Departmental Grant | 2016 | $115,000 | University of California, San Francisco, School of Medicine | ||
| Departmental Grant | 2016 | $115,000 | University of Nebraska Medical Center | ||
| Departmental Grant | 2016 | $115,000 | University of Oklahoma Health Sciences Center | ||
| Departmental Grant | 2016 | $115,000 | University of Pittsburgh School of Medicine | ||
| Departmental Grant | 2016 | $115,000 | University of Wisconsin-Madison School of Medicine & Public Health | ||
| Departmental Grant | 2016 | $115,000 | Vanderbilt University School of Medicine | ||
| Departmental Grant | 2016 | $115,000 | Washington University in Saint Louis School of Medicine | ||
| Departmental Grant | 2016 | $115,000 | Weill Cornell Medical College | ||
| Special Grant | 2016 | $32,000 | The Heed Ophthalmic Foundation | ||
| Resident Retreats, 2016 and 2017. Encourage and facilitate talented residents to pursue a career in academic ophthalmology. | |||||
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