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Research to Prevent Blindness

Grants Database

Research to Prevent Blindness (RPB) provides grants to high-performing U.S.-based departments of ophthalmology and to their high-potential investigators. Use our Grants Database to learn more. Award amounts for some grants are distributed over multiple years.

How to use the Grants Database

Refine your search by using the filter at left. Search by setting a date range, or filter your results by institution, research area keyword, or awardee.  Sort the table by clicking on any column header.  

Learn about an institution or individual by clicking on a name.

Learn about RPB-supported work by clicking on the text link "Research funded by this award," which will take you to our Research Database where you can refine and/or expand a search for published studies. (Note: In some cases this link will not be available because a researcher may have only recently received an award and has yet to publish findings.)

RPB Grant Awards from 2015 & 2016

96 Awards ($15,023,295)

RPB Grant Type
Year
Award
Research Area
Awardee
Institution
Career Development Award 2016 $300,000 Biochemistry, Molecular Biology, Retina Rajagopal, Rithwick / MD, PhD Washington University in Saint Louis School of Medicine
Will use animal models of diabetic eye disease to learn how fenofibrate, a drug clinically-approved to treat cholesterol, protects the eye from diabetes-related damage, as well as identify alternative therapeutic pathways that have fewer serious side effects.
Career Development Award 2016 $300,000 Physiological Optics, Visual Psychophysics Sabesan, Ramkumar / PhD University of Washington School of Medicine
Proposes to develop a specialized camera to capture how the retina’s rods and cones (responsible for turning light energy into shapes and colors) work in health and how they fail in diseases.
Medical Student Eye Research Fellowship 2016 $30,000 Retina Sears, Connie M. David Geffen School of Medicine at the University of California, Los Angeles
Conducting research at the University of California, Los Angeles.
Medical Student Eye Research Fellowship 2016 $30,000 Retinal Cell Biology Vo, Thomas University of California, Irvine, School of Medicine
Conducting research at the University of California, Irvine, School of Medicine.
Nelson Trust Award for Retinitis Pigmentosa 2016 $50,000 Retina Apte, Rajendra S. / MD, PhD Washington University in Saint Louis School of Medicine
Proposes to investigate whether a specific cause of metabolic dysfunction plays a role in photoreceptor and vision loss across types of retinitis pigmentosa.
Nelson Trust Award for Retinitis Pigmentosa 2016 $100,000 Retina Vandenberghe, Luk H. / PhD Harvard Medical School
Proposes to create a method for safe and efficient gene transfer (a proven treatment for retinitis pigmentosa) to the retina via an intravitreal route of injection, thereby avoiding the issues associated with the current and more invasive standard, subretinal injection.
RPB/SNF International Research Collaborators Award 2016 $75,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Pharmacology, Physiological Optics, Physiology, Strabismus, Visual Neuroscience, Visual Psychophysics Kohn, Adam / PhD Albert Einstein College of Medicine
Propose a collaborative effort to discover how feedback signals change the activity of nerve cells in the visual cortex, and therefore how they might influence our capacity to see.
Stein Innovation Award 2016 $300,000 Immunology, Microbiology Britton, Robert / PhD Baylor College of Medicine
Will explore the mechanisms by which intestinal tract bacteria impact the health of the eye, as well as identify specific bacteria that can be used therapeutically for dry eye and/or uveitis.
Stein Innovation Award 2016 $300,000 Glaucoma Jiang, Hongrui / PhD, MS University of Wisconsin-Madison School of Medicine & Public Health
Will develop micro-scale devices to measure real-time pressure at the optic nerve head and choroidal tension during accommodation—two processes thought to be potentially responsible for damage related to glaucoma.
Stein Innovation Award 2016 $300,000 Pharmacology, Physiology Malik, Asrar B. / PhD University of Illinois at Chicago College of Medicine
Proposes to address mechanisms regulating the overgrowth of retinal blood vessels in age-related macular degeneration (AMD) using eye drops instead of injections.
Career Development Award 2016 $300,000 Anatomy, Ocular Oncology, Pathology Daniels, Anthony Brent / MD, MSc Vanderbilt University School of Medicine
Seeking less toxic chemotherapeutic alternatives to currently-used regimens in the treatment of retinoblastoma (an eye cancer that develops in babies) in a rabbit model.
Career Development Award 2016 $300,000 Immunology, Microbiology Doan, Thuy A. / MD, PhD University of California, San Francisco, School of Medicine
Will use next-generation sequencing to comprehensively assess bacteria and viruses on and in the eye in normal health and disease and during treatment with antibiotics.
Career Development Award 2016 $300,000 Glaucoma Newman-Casey, Paula Anne / MD The Regents of the University of Michigan School of Medicine
Seeking to optimize implementation of behavioral interventions into current clinical operations in the treatment of glaucoma, with the goal of increasing medication adherence.
Disney Award for Amblyopia Research 2016 $100,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus Kiorpes, Lynne / PhD New York University School of Medicine
Will use psychophysical paradigms (stimulus-perception techniques) to explore attentional deficits in amblyopic children and to develop strategies that will improve not only visual acuity but also non-visual acuity perceptual deficits in amblyopia treatment.
Disney Award for Amblyopia Research 2016 $100,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus McGee, Aaron W. / PhD University of Louisville School of Medicine
Seeks to establish optimal, gene-inhibiting, drug intervention targets in the development of the visual pathway (in mice) in order to prolong the period of visual plasticity in the visual system – a sensitive period which is related to amblyopia in humans.
International Research Scholar Award 2016 $1,295 Biochemistry, Cornea, Immunology, Microbiology Schenke-Layland, Katja / PhD, MSc Keck School of Medicine of the University of Southern California
Develop a novel stem cell-based tissue engineering strategy to regenerate lacrimal glands that are damaged by the autoimmune inflammation associated with Sjögren’s syndrome.
Low Vision Research Award 2016 $100,000 Manduchi, Roberto / PhD University of California, Santa Cruz
Developing an economical and easy-to-use low vision screen magnifier that will enable scrolling control by means of the viewer’s own gaze, rather than using a mouse or trackpad.
Low Vision Research Award 2016 $300,000 Merabet, Lotfi B. / OD, PhD, MPH Harvard Medical School
Seeking to establish linkages between observed perceptual deficits and the underlying neurophysiology in cortical visual impairment (CVI), a leading cause of pediatric low vision.
Medical Student Eye Research Fellowship 2016 $30,000 Retina Gupta, Priya Rani Harvard Medical School
Conducting research at Harvard Medical School / MEEI.
Medical Student Eye Research Fellowship 2016 $30,000 Biochemistry, Pharmacology, Physiology, Retina, Retinal Cell Biology Sengillo, Jesse D. Columbia University College of Physicians & Surgeons
Conducting research at Columbia University College of Physicians & Surgeons.
Physician-Scientist Award 2016 $300,000 Cornea Chan, Matilda F. / MD, PhD University of California, San Francisco, School of Medicine
Investigating the hypothesis that a specific form of DNA modification—DNA methylation—plays a significant role in the development of Fuchs Endothelial Corneal Dystrophy (FECD); testing an FDA-approved drug that is able to reverse DNA methylation in cancer cells to reverse it also in the cornea.
Physician-Scientist Award 2016 $300,000 Retina Sun, Jennifer K. / MD, MPH Harvard Medical School
Using noninvasive optical coherence tomography angiography to establish changes in the retinal capillary network as biomarkers that predict retinal neural damage leading to vision loss or the worsening of diabetic retinopathy over time.
Special Grant 2016 $125,000 Association of University Professors of Ophthalmology
AUPO is a key ally in RPB's commitment to enrich the development of the Chairs, Directors of Research, and other leaders from departments of ophthalmology.
Special Scholar Award 2016 $75,000 Retina Lad, Eleonora / MD, PhD Duke University School of Medicine
Understanding the role of monocytes (type of white blood cell) in dry AMD in order to support the concept that monocytes should be investigated as therapeutic targets for treatment of dry AMD.
Special Scholar Award 2016 $25,000 Physiological Optics, Visual Psychophysics McAnany, J. Jason / PhD University of Illinois at Chicago College of Medicine
Developing a “multi-modal functional assay” for complete characterization of early neural changes in patients with diabetic retinopathy (DR), with the goal of early detection and diagnosis in at-risk populations.
Special Scholar Award 2016 $55,000 Retina, Retinal Cell Biology McGill, Trevor / PhD Oregon Health & Science University School of Medicine
Developing a novel contrast agent and cell viability marker for use with optical coherence tomography to document the survival, migration, and integration of transplanted, therapeutic stem cells in the treatment of retinal degenerative diseases.
Special Scholar Award 2016 $60,000 Pharmacology, Physiology, Retina, Visual Neuroscience Wong, Kwoon Y. / PhD The Regents of the University of Michigan School of Medicine
Seeking to learn how intrinsically photosensitive retinal ganglion cells (ipRGCs) respond to light and interact with other retinal cells in order to potentially improve the visual capability of blind and low-vision patients.
Stein Innovation Award 2016 $300,000 Pharmacology, Physiology Puro, Donald G. / MD, PhD The Regents of the University of Michigan School of Medicine
Exploring the role of ion channels in the response of tear-film-stabilizing goblet cells to changes in the salt content of tears as a potentially new avenue to develop more effective therapeutic strategies to combat dry eye.
Stein Innovation Award 2016 $300,000 Retina Schwartz, Daniel M. / MD University of California, San Francisco, School of Medicine
Developing and testing a novel light-activated drug that potentially can arrest progressive ocular growth and macular stretching that occurs in degenerative myopia.
Stein Innovation Award 2016 $300,000 Cell Biology, Retina, Retinal Cell Biology Sung, Ching-Hwa / PhD Weill Cornell Medical College
Testing the hypothesis that manipulating signals to structures on the surface of cultured retinal progenitor cells can generate specific types of retinal neurons essential to cell replacement therapy for damaged retinas.
Departmental Grant 2016 $115,000 Cleveland Clinic Lerner College of Medicine of CWRU
Departmental Grant 2016 $115,000 Emory University School of Medicine
Departmental Grant 2016 $115,000 Harvard Medical School
Departmental Grant 2016 $115,000 Indiana University School of Medicine
Departmental Grant 2016 $115,000 Johns Hopkins University School of Medicine
Departmental Grant 2016 $115,000 Keck School of Medicine of the University of Southern California
Departmental Grant 2016 $115,000 Louisiana State University Health Sciences Center in New Orleans
Departmental Grant 2016 $115,000 Mayo Clinic, College of Medicine
Departmental Grant 2016 $115,000 Oregon Health & Science University School of Medicine
Departmental Grant 2016 $115,000 University of California, San Francisco, School of Medicine
Departmental Grant 2016 $115,000 University of Nebraska Medical Center
Departmental Grant 2016 $115,000 University of Oklahoma Health Sciences Center
Departmental Grant 2016 $115,000 University of Pittsburgh School of Medicine
Departmental Grant 2016 $115,000 University of Wisconsin-Madison School of Medicine & Public Health
Departmental Grant 2016 $115,000 Vanderbilt University School of Medicine
Departmental Grant 2016 $115,000 Washington University in Saint Louis School of Medicine
Departmental Grant 2016 $115,000 Weill Cornell Medical College
Special Grant 2016 $32,000 The Heed Ophthalmic Foundation
Resident Retreats, 2016 and 2017. Encourage and facilitate talented residents to pursue a career in academic ophthalmology.
Career Development Award 2015 $300,000 Anatomy, Glaucoma, Ocular Oncology, Pathology, Pharmacology, Physiology Huang, Alex / MD, PhD David Geffen School of Medicine at the University of California, Los Angeles
To develop aqueous angiography as an aqueous humor outflow imaging technique -- a tool that may improve the basic understanding of fluid flow in the eye and/or clinical results from minimally invasive glaucoma surgeries (MIGS).
Career Development Award 2015 $300,000 Anatomy, Ocular Oncology, Pathology, Pharmacology, Physiological Optics, Physiology, Retina, Retinal Cell Biology, Visual Neuroscience, Visual Psychophysics Schallek, Jesse / PhD University of Rochester School of Medicine & Dentistry
To use a use a custom-built, high resolution camera (adaptive optics scanning light ophthalmoscope) to study how blood cells interact with the capillary endothelium in the early stages of microvasculopathy in diabetes.
Departmental Grant 2015 $300,000 University of Colorado School of Medicine
Medical Student Eye Research Fellowship 2015 $30,000 Clinical, Epidemiologic Dong, Zachary Michael University of Pittsburgh School of Medicine
Conducting research at University of Pittsburgh School of Medicine.
Medical Student Eye Research Fellowship 2015 $30,000 Retinal Cell Biology Kim, Clifford Harvard Medical School
Conducting research at Harvard Medical School / MEEI.
Medical Student Eye Research Fellowship 2015 $30,000 Retinal Cell Biology Vu, Khiem University of Texas Southwestern Medical Center at Dallas
Conducting research at University of Texas Southwestern Medical Center at Dallas.
Nelson Trust Award for Retinitis Pigmentosa 2015 $100,000 Retina Duncan, Jacque L. / MD University of California, San Francisco, School of Medicine
Will use adaptive optics scanning laser ophthalmoscopy to probe photoreceptor structure and function in eyes with retinitis pigmentosa at the earliest stages of disease.
Nelson Trust Award for Retinitis Pigmentosa 2015 $100,000 Retina, Retinal Cell Biology Wen, Rong / MD, PhD University of Miami Miller School of Medicine
To carry out pre-clinical studies on three treatment strategies for retinitis pigmentosa, including pharmacological therapy, gene therapy, and neuroprotective therapies.
Stein Innovation Award 2015 $300,000 Biochemistry, Cell Biology, Development, Molecular Biology, Retinal Cell Biology Näär, Anders M. / PhD Harvard Medical School
To investigate gene regulation of cholesterol/lipid homeostasis in the development of age-related macular degeneration (AMD).
Stein Innovation Award 2015 $300,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus Stryker, Michael P. / PhD University of California, San Francisco, School of Medicine
To reveal which cortical circuits are altered in amblyopia in order to target and stimulate signaling mechanisms which could promote recovery during adulthood.
Stein Innovation Award 2015 $300,000 Cell Biology, Development Zambidis, Elias T. / MD, PhD Johns Hopkins University School of Medicine
To develop mature human retinas in mice by injecting human induced pluripotent stem cells into mouse blastocysts (cluster of cells from which an embryo arises).
Stein Professorship/Extension 2015 $250,000 Biochemistry, Molecular Biology, Retinal Cell Biology Antonetti, David / PhD The Regents of the University of Michigan School of Medicine
To restore diabetes-damaged blood vessels in the hopes of repairing the retinal vascular network and preventing vision loss.
Career Development Award 2015 $300,000 Retinal Cell Biology Hulleman, John D. / PhD University of Texas Southwestern Medical Center at Dallas
Using protein engineering to test the hypothesis that selective activation of a specific oxidative stress response will protect the retinal pigment epithelium cell layer from the initiating events of AMD.
Career Development Award 2015 $300,000 Eye Movements, Strabismus, Amblyopia, Neuro-Ophthalmology, Immunology, Microbiology Levin, Marc Harris / MD, PhD University of California, San Francisco, School of Medicine
To identify mechanisms that lead to optic nerve inflammation in neuromyelitis optica and other disorders.
Career Development Award 2015 $300,000 Physiology, Pharmacology, Retinal Cell Biology, Stem Cell Singh, Ruchira / PhD University of Rochester School of Medicine & Dentistry
To use patient-derived retinal stem cell models to understand the effect of the environment (blue light, cigarette smoke, free iron) on development and progression of AMD.
Career Development Award 2015 $300,000 Glaucoma Tehrani, Shandiz / MD, PhD Oregon Health & Science University School of Medicine
To develop a method to locally deliver therapeutic molecules to the optic nerve head in vivo, with the goal of stabilizing structures to prevent axonal injury in experimental glaucoma.
Departmental Grant 2015 $115,000 Cleveland Clinic Lerner College of Medicine of CWRU
Departmental Grant 2015 $115,000 Emory University School of Medicine
Departmental Grant 2015 $115,000 Harvard Medical School
Departmental Grant 2015 $115,000 Indiana University School of Medicine
Departmental Grant 2015 $115,000 Johns Hopkins University School of Medicine
Departmental Grant 2015 $115,000 Keck School of Medicine of the University of Southern California
Departmental Grant 2015 $115,000 Louisiana State University Health Sciences Center in New Orleans
Departmental Grant 2015 $115,000 Mayo Clinic, College of Medicine
Departmental Grant 2015 $115,000 Oregon Health & Science University School of Medicine
Departmental Grant 2015 $115,000 University of California, San Francisco, School of Medicine
Departmental Grant 2015 $115,000 University of Cincinnati College of Medicine
Departmental Grant 2015 $115,000 University of Nebraska Medical Center
Departmental Grant 2015 $115,000 University of North Carolina at Chapel Hill School of Medicine
Departmental Grant 2015 $115,000 University of Oklahoma Health Sciences Center
Departmental Grant 2015 $115,000 University of Pittsburgh School of Medicine
Departmental Grant 2015 $115,000 University of Tennessee Health Science Center
Departmental Grant 2015 $115,000 University of Wisconsin-Madison School of Medicine & Public Health
Departmental Grant 2015 $115,000 Vanderbilt University School of Medicine
Departmental Grant 2015 $115,000 Washington University in Saint Louis School of Medicine
Departmental Grant 2015 $115,000 Weill Cornell Medical College
Departmental Grant 2015 $115,000 Yale University School of Medicine
Medical Student Eye Research Fellowship 2015 $30,000 Retinal Cell Biology Diaz-Aguilar, Daniel Harvard Medical School
Elucidating a potential therapeutic modality for preservation of vision in advanced AMD patients with geographic atrophy.
Physician-Scientist Award 2015 $300,000 Cornea, Dry Eye, Stem Cell Shindler, Kenneth S. / MD, PhD University of Pennsylvania School of Medicine
Evaluating novel therapies that prevent retinal ganglion cell (RGC) damage and visual loss in optic neuritis: the role of Dexras1, a small G protein, in RGC death; modulating iron uptake as a treatment for optic neuritis.
Physician-Scientist Award 2015 $300,000 Retina Zacks, David / MD, PhD The Regents of the University of Michigan School of Medicine
Defining the mechanism by which dysregulation of autophagy (a central biologic process that helps regulate cellular health and response to metabolic and oxidative stress) in the retinal pigment epithelium results in age-related degeneration and how activation of compensatory stress-response pathways serves to reduce the rate of degeneration.
Special Grant 2015 $150,000 General Operating Support Association of University Professors of Ophthalmology
AUPO is a key ally in RPB's commitment to enrich the development of the Chairs, Directors of Research, and other leaders from departments of ophthalmology.
Special Scholar Award 2015 $55,000 Eye Movements, Strabismus, Amblyopia, Neuro-Ophthalmology Moss, Heather E. / MD, PhD University of Illinois at Chicago College of Medicine
Defining how changes in blood vessels in the eyes, in the structure of the optic nerve and in the electrical activity of the eyes in Idiopathic intracranial hypertension(IIH) patients can be used to measure disease development and treatment success, and to predict future vision loss in IIH.
Special Scholar Award 2015 $60,000 Retina, Retinal Cell Biology, Biochemistry, Molecular Biology Nair, Kayarat Saidas / PhD University of California, San Francisco, School of Medicine
Seeking ways to make a subset of mammalian M�ller cells more amenable to support retinal regeneration, with the potential to restore vision.
Special Scholar Award 2015 $25,000 Retina Saint-Geniez, Magali / PhD Harvard Medical School
Characterizing the effect of retinal detachment on photoreceptor metabolism and evaluating the therapeutic benefits of PGC-1 transcriptional coactivator isoforms on photoreceptor response to energetic stress and survival secondary to retinal detachment.
Special Scholar Award 2015 $75,000 Retinal Cell Biology, Biochemistry, Molecular Biology Sodhi, Akrit S. / MD, PhD Johns Hopkins University School of Medicine
Identifying and validating safe and effective targets for the treatment of abnormal �leaky� blood vessels in wet AMD.
Stein Innovation Award 2015 $300,000 Retina Dean, Douglas / PhD University of Louisville School of Medicine
Investigating central vision rescue in retinitis pigmentosa by restoring rod dependent cone function via rod precursor cell transplantation.
Stein Innovation Award 2015 $300,000 Glaucoma Kaufman, Paul L. / MD University of Wisconsin-Madison School of Medicine & Public Health
Expanding glaucoma therapeutics by using micro invasive surgical techniques to deliver viral vector gene therapy constructs directly to tissues of the outflow pathways in the eye that are affected by glaucoma: the trabecular meshwork and Schlemm's canal.
Stein Innovation Award 2015 $300,000 Glaucoma, Nanophotonics Sretavan, David W. / MD, PhD University of California, San Francisco, School of Medicine
Developing a novel, nanosensor method of intraocular pressure (IOP) tracking using light and a highly miniaturized implant for the ongoing, automated monitoring of IOP in glaucoma patients.

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