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Research to Prevent Blindness

Grants Database

Research to Prevent Blindness (RPB) provides grants to high-performing U.S.-based departments of ophthalmology and to their high-potential investigators. Use our Grants Database to learn more. Award amounts for some grants are distributed over multiple years.

How to use the Grants Database

Refine your search by using the filter at left. Search by setting a date range, or filter your results by institution, research area keyword, or awardee.  Sort the table by clicking on any column header.  

Learn about an institution or individual by clicking on a name.

Learn about RPB-supported work by clicking on the text link "Research funded by this award," which will take you to our Research Database where you can refine and/or expand a search for published studies. (Note: In some cases this link will not be available because a researcher may have only recently received an award and has yet to publish findings.)

RPB Grant Awards from 2016 & 2017

83 Awards ($13,792,295)

RPB Grant Type
Year
Award
Research Area
Awardee
Institution
Career Development Award 2017 $300,000 Ocular Oncology, Pathology, Retina Afshar, Armin / MD, MBA University of California, San Francisco, School of Medicine
Will undertake research to improve our understanding of the patient prognosis of uveal melanoma, a devastating ocular cancer, including outcomes related to the eye, quality of life and survival after radiotherapy.
Career Development Award 2017 $300,000 Retina Byrne, Leah / PhD University of Pittsburgh School of Medicine
Proposes to create a flexible method of gene and protein delivery in the retina, where gene therapy represents a highly promising approach to treating retinal diseases, through a modular system of small viruses.
Career Development Award 2017 $300,000 Imaging, Retina Chen, Xi / MD, PhD Duke University School of Medicine
Proposes to utilize a noninvasive advanced imaging technique to visualize, in real-time, the development of blood vessels in the retina in human infants.
Career Development Award 2017 $300,000 Glaucoma, Pharmacology, Physiology Pitha, Ian / MD, PhD Johns Hopkins University School of Medicine
Will investigate a cellular process that could lead to a new therapeutic target (in the form of manipulation of peripapillary scleral fibroblast activity) for neuroprotection from glaucoma-related retinal ganglion cell death and vision loss.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2017 $300,000 AMD, Retina Bowes Rickman, Catherine / PhD Duke University School of Medicine
Proposes to use unique and relevant models of chronic, dry AMD to test three therapeutic approaches that will shape strategies for targeting the complement pathway versus targeting cholesterol versus a combined therapeutic approach targeting both pathways.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2017 $300,000 AMD, Retina Green, Jordan / PhD Johns Hopkins University School of Medicine
Proposes to develop a breakthrough translational therapy for neovascular (wet) AMD, as well as a biodegradable drug delivery system that would allow sustained, 6-month release.
Catalyst Award for Innovative Research Approaches for Age-Related Macular Degeneration 2017 $300,000 AMD, Retina Sinha, Debasish / PhD University of Pittsburgh School of Medicine
Will develop a treatment for early, dry AMD that works by rejuvenating impaired lysosomal function.
Medical Student Eye Research Fellowship 2017 $30,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus, Visual Neuroscience Asanad, Samuel David Geffen School of Medicine at the University of California, Los Angeles
Conducting research at David Geffen School of Medicine, University of California, Los Angeles.
Medical Student Eye Research Fellowship 2017 $30,000 Immunology, Microbiology Heisel, Curtis The Regents of the University of Michigan School of Medicine
Conducting research at the The Regents of the University of Michigan School of Medicine.
Medical Student Eye Research Fellowship 2017 $30,000 Biochemistry, Molecular Biology, Pharmacology, Physiology, Retina, Retinal Cell Biology Jauregui, Ruben Columbia University College of Physicians & Surgeons
Conducting research at Columbia University College of Physicians & Surgeons.
Physician-Scientist Award 2017 $300,000 Glaucoma Samuels, Brian / MD, PhD University of Alabama at Birmingham School of Medicine
Will investigate optic nerve biomechanics in the tree shrew, a potential new, economical animal model for glaucoma, which overcomes many of the biological barriers found in current animal models.
Physician-Scientist Award 2017 $300,000 Retinal Cell Biology Sears, Jonathan Eliot / MD Cleveland Clinic Lerner College of Medicine of CWRU
Proposes to explore the ability of liver stimulation (via hypoxia-inducible factor stabilization) to protect blood vessels in the eye for infants with retinopathy of prematurity (ROP), a major cause of childhood blindness.
RPB/SNF International Research Collaborators Award 2017 $75,000 Anatomy, Ocular Oncology, Pathology Cobrinik, David / MD, PhD Keck School of Medicine of the University of Southern California
Proposes to determine how rod-derived cone viability factor (RdCVF) expression is regulated in developing cone photoreceptors, both to enable ways to suppress RdCVF in retinoblastoma (an ocular cancer most common in childhood) and to develop approaches to sustain RdCVF expression in patients with retinal degenerations.
Special Grant 2017 $34,000 The Heed Ophthalmic Foundation
Residents Retreat, 2017 and 2018. Encourage and facilitate talented residents to pursue a career in academic ophthalmology.
Stein Innovation Award 2017 $300,000 Cell Biology, Genetics, Retinal Cell Biology, Systems Biology Katsanis, Nicholas / PhD Duke University School of Medicine
Proposes to test a new therapeutic target (which consists of suppressing gene USP35) for retinal degenerative diseases, such as retinitis pigmentosa (RP), using cell-based screens in zebrafish.
Stein Innovation Award 2017 $300,000 Anatomy, Cell Biology, Glaucoma, Ocular Oncology, Pathology, Pharmacology, Physiology, Retinal Cell Biology Nedergaard, Maiken / MD, DMSc University of Rochester School of Medicine & Dentistry
Will characterize the biology and ocular physiology of the glymphatic system, a recently discovered macroscopic waste clearance system for the central nervous system that is required for normal brain function, but also has a critical role in neurodegenerative disease.
Stein Innovation Award 2017 $300,000 Genetics, Systems Biology Neuringer, Martha / PhD Oregon Health & Science University School of Medicine
Will utilize new genetic technology to create monkey models of human-like retinal degenerative diseases, such as achromatopsia, a disabling disease affecting daylight vision, visual acuity and color vision.
Stein Innovation Award 2017 $300,000 Pharmacology, Physiology Semenza, Gregg L. / MD, PhD Johns Hopkins University School of Medicine
Proposes to treat excessive blood vessel grown (as seen in age-related macular degeneration and diabetic macular edema) by developing more potent and specific small molecule hypoxia-inducible factor (HIF) inhibitors in long-lasting formulations.
Stein Professorship/Extension 2017 $250,000 Retinal Cell Biology Perkins, Brian / PhD Cleveland Clinic Lerner College of Medicine of CWRU
Will use zebrafish research to identify the contribution of specific micro-ribonucleic acids (mi-RNAs)—building blocks of life that help to code, regulate and express genes—to photoreceptor survival, as well as provide a unique collection of mutant zebrafish that can be used to determine the role of each mi-RNA in regulating cellular pathways.
Disney Award for Amblyopia Research 2017 $100,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Pharmacology, Physiology, Strabismus, Visual Neuroscience Aton, Sara / PhD The Regents of the University of Michigan School of Medicine
Investigating the role of sleep in modifying plasticity of the visual system, based on results of previous research.
Career Development Award 2017 $300,000 Biochemistry, Molecular Biology, Pharmacology, Physiology, Retina, Retinal Cell Biology, Visual Neuroscience Duan, Xin / PhD University of California, San Francisco, School of Medicine
Gain a deep understanding of optic nerve regeneration via synapse formation and neural circuit mapping.
Career Development Award 2017 $300,000 Immunology, Microbiology Pepple, Kathryn L. / MD, PhD University of Washington School of Medicine
Developing an unbiased, non-invasive, quantitative, in vivo assay for uveitis, using bioluminescence.
Low Vision Research Award 2017 $300,000 Low Vision Gardner, Justin / PhD Stanford University School of Medicine
Measuring and tracking visual and auditory sensory performance following sight-restoring surgery, such as cataract removal or corneal replacement, for adult humans.
Low Vision Research Award 2017 $100,000 Low Vision Luo, Gang / PhD Harvard Medical School
Designing a mobile application to perform keyword searches in real-world environments to enhance the visual search capabilities of persons with low vision.
Medical Student Eye Research Fellowship 2017 $30,000 Clinical, Epidemiologic Liu, Tianyu University of Pennsylvania School of Medicine
Conducting research at the University of Pennsylvania School of Medicine.
Medical Student Eye Research Fellowship 2017 $30,000 Clinical, Optic Neuropathy Udeh, Adanna University of Miami Miller School of Medicine
Conducting research at the University of Miami Miller School of Medicine.
RPB/SNF International Research Collaborators Award 2017 $75,000 Glaucoma, Retina, Retinal Cell Biology Mandal, Nawajes / PhD University of Tennessee Health Science Center
Testing whether anti-ceramide gene therapy, delivered through a specific model, will be protective in four different animal models of retinal degeneration.
Special Grant 2017 $165,000 Association of University Professors of Ophthalmology
AUPO is a key ally in RPB's commitment to enrich the development of the Chairs, Directors of Research, and other leaders from departments of ophthalmology.
Special Grant 2017 $55,000 Drug Delivery Ensign, Laura / PhD Johns Hopkins University School of Medicine
Investigating delivery of drug microcrystals to the suprachoroidal space, thereby avoiding potential complications with intravitreal injections.
Special Scholar Award 2017 $25,000 Biochemistry, Molecular Biology, Retina, Retinal Cell Biology Chen, Jing / PhD Harvard Medical School
Investigating the role of a novel redox (reduction/oxidation) sensitive nuclear receptor in mediating oxidative stress-dependent RPE (retinal pigment epithelium) and retinal dysfunction, which contributes to the pathogenesis of age-related macular degeneration (AMD).
Special Scholar Award 2017 $55,000 Drug Delivery Ensign, Laura / PhD Johns Hopkins University School of Medicine
Investigating delivery of drug microcrystals to the suprachoroidal space, thereby avoiding potential complications with intravitreal injections.
Special Scholar Award 2017 $75,000 Retina Hunter, Jennifer J. / PhD University of Rochester School of Medicine & Dentistry
Establishing a research program in 2-photon fluorescence imaging of the retina using an adaptive optics scanning light ophthalmoscope (AOSLO). Also proposing to add fluorescent lifetime imaging (FLIM) capability to an AOSLO, thereby allowing measurement of lipofuscin composition in retinal pigment epithelial cells, which is relevant to age-related macula degeneration, Stargardt disease, and other macular diseases.
Special Scholar Award 2017 $60,000 Imaging, Retina Jia, Yali / PhD Oregon Health & Science University School of Medicine
Developing wide-field and projection-resolved optical coherence tomography angiography (OCTA) and apply them to the diagnosis and evaluation of inherited retinal diseases.
Stein Innovation Award 2017 $300,000 Cornea Funderburgh, James L. / PhD University of Pittsburgh School of Medicine
Define roles for stem cell-derived extracellular vesicles and the mechanism by which they induce corneal regeneration and explore the potential to replace therapy involving live stem cells with a defined mixture of bio-molecules.
Stein Innovation Award 2017 $300,000 Anatomy, Biochemistry, Cell Biology, Molecular Biology, Ocular Oncology, Pathology, Pharmacology, Physiology, Retina, Retinal Cell Biology Sheibani, Nader / PhD University of Wisconsin-Madison School of Medicine & Public Health
Investigating the role of mitochondrial carbonic anhydrase and its inhibition on pericytes loss.
Career Development Award 2016 $300,000 Biochemistry, Molecular Biology, Retina Rajagopal, Rithwick / MD, PhD Washington University in Saint Louis School of Medicine
Will use animal models of diabetic eye disease to learn how fenofibrate, a drug clinically-approved to treat cholesterol, protects the eye from diabetes-related damage, as well as identify alternative therapeutic pathways that have fewer serious side effects.
Career Development Award 2016 $300,000 Physiological Optics, Visual Psychophysics Sabesan, Ramkumar / PhD University of Washington School of Medicine
Proposes to develop a specialized camera to capture how the retina’s rods and cones (responsible for turning light energy into shapes and colors) work in health and how they fail in diseases.
Medical Student Eye Research Fellowship 2016 $30,000 Retina Sears, Connie M. David Geffen School of Medicine at the University of California, Los Angeles
Conducting research at the University of California, Los Angeles.
Medical Student Eye Research Fellowship 2016 $30,000 Retinal Cell Biology Vo, Thomas University of California, Irvine, School of Medicine
Conducting research at the University of California, Irvine, School of Medicine.
Nelson Trust Award for Retinitis Pigmentosa 2016 $50,000 Retina Apte, Rajendra S. / MD, PhD Washington University in Saint Louis School of Medicine
Proposes to investigate whether a specific cause of metabolic dysfunction plays a role in photoreceptor and vision loss across types of retinitis pigmentosa.
Nelson Trust Award for Retinitis Pigmentosa 2016 $100,000 Retina Vandenberghe, Luk H. / PhD Harvard Medical School
Proposes to create a method for safe and efficient gene transfer (a proven treatment for retinitis pigmentosa) to the retina via an intravitreal route of injection, thereby avoiding the issues associated with the current and more invasive standard, subretinal injection.
RPB/SNF International Research Collaborators Award 2016 $75,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Pharmacology, Physiological Optics, Physiology, Strabismus, Visual Neuroscience, Visual Psychophysics Kohn, Adam / PhD Albert Einstein College of Medicine
Propose a collaborative effort to discover how feedback signals change the activity of nerve cells in the visual cortex, and therefore how they might influence our capacity to see.
Stein Innovation Award 2016 $300,000 Immunology, Microbiology Britton, Robert / PhD Baylor College of Medicine
Will explore the mechanisms by which intestinal tract bacteria impact the health of the eye, as well as identify specific bacteria that can be used therapeutically for dry eye and/or uveitis.
Stein Innovation Award 2016 $300,000 Glaucoma Jiang, Hongrui / PhD, MS University of Wisconsin-Madison School of Medicine & Public Health
Will develop micro-scale devices to measure real-time pressure at the optic nerve head and choroidal tension during accommodation—two processes thought to be potentially responsible for damage related to glaucoma.
Stein Innovation Award 2016 $300,000 Pharmacology, Physiology Malik, Asrar B. / PhD University of Illinois at Chicago College of Medicine
Proposes to address mechanisms regulating the overgrowth of retinal blood vessels in age-related macular degeneration (AMD) using eye drops instead of injections.
Career Development Award 2016 $300,000 Anatomy, Ocular Oncology, Pathology Daniels, Anthony Brent / MD, MSc Vanderbilt University School of Medicine
Seeking less toxic chemotherapeutic alternatives to currently-used regimens in the treatment of retinoblastoma (an eye cancer that develops in babies) in a rabbit model.
Career Development Award 2016 $300,000 Immunology, Microbiology Doan, Thuy A. / MD, PhD University of California, San Francisco, School of Medicine
Will use next-generation sequencing to comprehensively assess bacteria and viruses on and in the eye in normal health and disease and during treatment with antibiotics.
Career Development Award 2016 $300,000 Glaucoma Newman-Casey, Paula Anne / MD The Regents of the University of Michigan School of Medicine
Seeking to optimize implementation of behavioral interventions into current clinical operations in the treatment of glaucoma, with the goal of increasing medication adherence.
Disney Award for Amblyopia Research 2016 $100,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus Kiorpes, Lynne / PhD New York University School of Medicine
Will use psychophysical paradigms (stimulus-perception techniques) to explore attentional deficits in amblyopic children and to develop strategies that will improve not only visual acuity but also non-visual acuity perceptual deficits in amblyopia treatment.
Disney Award for Amblyopia Research 2016 $100,000 Amblyopia, Eye Movements, Neuro-Ophthalmology, Strabismus McGee, Aaron W. / PhD University of Louisville School of Medicine
Seeks to establish optimal, gene-inhibiting, drug intervention targets in the development of the visual pathway (in mice) in order to prolong the period of visual plasticity in the visual system – a sensitive period which is related to amblyopia in humans.
International Research Scholar Award 2016 $1,295 Biochemistry, Cornea, Immunology, Microbiology Schenke-Layland, Katja / PhD, MSc Keck School of Medicine of the University of Southern California
Develop a novel stem cell-based tissue engineering strategy to regenerate lacrimal glands that are damaged by the autoimmune inflammation associated with Sjögren’s syndrome.
Low Vision Research Award 2016 $100,000 Manduchi, Roberto / PhD University of California, Santa Cruz
Developing an economical and easy-to-use low vision screen magnifier that will enable scrolling control by means of the viewer’s own gaze, rather than using a mouse or trackpad.
Low Vision Research Award 2016 $300,000 Merabet, Lotfi B. / OD, PhD, MPH Harvard Medical School
Seeking to establish linkages between observed perceptual deficits and the underlying neurophysiology in cortical visual impairment (CVI), a leading cause of pediatric low vision.
Medical Student Eye Research Fellowship 2016 $30,000 Retina Gupta, Priya Rani Harvard Medical School
Conducting research at Harvard Medical School / MEEI.
Medical Student Eye Research Fellowship 2016 $30,000 Biochemistry, Pharmacology, Physiology, Retina, Retinal Cell Biology Sengillo, Jesse D. Columbia University College of Physicians & Surgeons
Conducting research at Columbia University College of Physicians & Surgeons.
Physician-Scientist Award 2016 $300,000 Cornea Chan, Matilda F. / MD, PhD University of California, San Francisco, School of Medicine
Investigating the hypothesis that a specific form of DNA modification—DNA methylation—plays a significant role in the development of Fuchs Endothelial Corneal Dystrophy (FECD); testing an FDA-approved drug that is able to reverse DNA methylation in cancer cells to reverse it also in the cornea.
Physician-Scientist Award 2016 $300,000 Retina Sun, Jennifer K. / MD, MPH Harvard Medical School
Using noninvasive optical coherence tomography angiography to establish changes in the retinal capillary network as biomarkers that predict retinal neural damage leading to vision loss or the worsening of diabetic retinopathy over time.
Special Grant 2016 $125,000 Association of University Professors of Ophthalmology
AUPO is a key ally in RPB's commitment to enrich the development of the Chairs, Directors of Research, and other leaders from departments of ophthalmology.
Special Scholar Award 2016 $75,000 Retina Lad, Eleonora / MD, PhD Duke University School of Medicine
Understanding the role of monocytes (type of white blood cell) in dry AMD in order to support the concept that monocytes should be investigated as therapeutic targets for treatment of dry AMD.
Special Scholar Award 2016 $25,000 Physiological Optics, Visual Psychophysics McAnany, J. Jason / PhD University of Illinois at Chicago College of Medicine
Developing a “multi-modal functional assay” for complete characterization of early neural changes in patients with diabetic retinopathy (DR), with the goal of early detection and diagnosis in at-risk populations.
Special Scholar Award 2016 $55,000 Retina, Retinal Cell Biology McGill, Trevor / PhD Oregon Health & Science University School of Medicine
Developing a novel contrast agent and cell viability marker for use with optical coherence tomography to document the survival, migration, and integration of transplanted, therapeutic stem cells in the treatment of retinal degenerative diseases.
Special Scholar Award 2016 $60,000 Pharmacology, Physiology, Retina, Visual Neuroscience Wong, Kwoon Y. / PhD The Regents of the University of Michigan School of Medicine
Seeking to learn how intrinsically photosensitive retinal ganglion cells (ipRGCs) respond to light and interact with other retinal cells in order to potentially improve the visual capability of blind and low-vision patients.
Stein Innovation Award 2016 $300,000 Pharmacology, Physiology Puro, Donald G. / MD, PhD The Regents of the University of Michigan School of Medicine
Exploring the role of ion channels in the response of tear-film-stabilizing goblet cells to changes in the salt content of tears as a potentially new avenue to develop more effective therapeutic strategies to combat dry eye.
Stein Innovation Award 2016 $300,000 Retina Schwartz, Daniel M. / MD University of California, San Francisco, School of Medicine
Developing and testing a novel light-activated drug that potentially can arrest progressive ocular growth and macular stretching that occurs in degenerative myopia.
Stein Innovation Award 2016 $300,000 Cell Biology, Retina, Retinal Cell Biology Sung, Ching-Hwa / PhD Weill Cornell Medical College
Testing the hypothesis that manipulating signals to structures on the surface of cultured retinal progenitor cells can generate specific types of retinal neurons essential to cell replacement therapy for damaged retinas.
Departmental Grant 2016 $115,000 Cleveland Clinic Lerner College of Medicine of CWRU
Departmental Grant 2016 $115,000 Emory University School of Medicine
Departmental Grant 2016 $115,000 Harvard Medical School
Departmental Grant 2016 $115,000 Indiana University School of Medicine
Departmental Grant 2016 $115,000 Johns Hopkins University School of Medicine
Departmental Grant 2016 $115,000 Keck School of Medicine of the University of Southern California
Departmental Grant 2016 $115,000 Louisiana State University Health Sciences Center in New Orleans
Departmental Grant 2016 $115,000 Mayo Clinic, College of Medicine
Departmental Grant 2016 $115,000 Oregon Health & Science University School of Medicine
Departmental Grant 2016 $115,000 University of California, San Francisco, School of Medicine
Departmental Grant 2016 $115,000 University of Nebraska Medical Center
Departmental Grant 2016 $115,000 University of Oklahoma Health Sciences Center
Departmental Grant 2016 $115,000 University of Pittsburgh School of Medicine
Departmental Grant 2016 $115,000 University of Wisconsin-Madison School of Medicine & Public Health
Departmental Grant 2016 $115,000 Vanderbilt University School of Medicine
Departmental Grant 2016 $115,000 Washington University in Saint Louis School of Medicine
Departmental Grant 2016 $115,000 Weill Cornell Medical College
Special Grant 2016 $32,000 The Heed Ophthalmic Foundation
Resident Retreats, 2016 and 2017. Encourage and facilitate talented residents to pursue a career in academic ophthalmology.

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