netbook
desktop
mobile
tablet-landscape
tablet
phone-landscape
phone
Research to Prevent Blindness

Could An Eye Exam Reveal Alzheimer’s Disease?

According to a news report from Duke Eye Center, a study of more than 200 people (reported in the journal Ophthalmology Retinasuggests that loss of blood vessels in the retina could signal Alzheimer’s disease. The research was supported in part by an RPB unrestricted grant to the Duke University Department of Ophthalmology.

In people with healthy brains, microscopic blood vessels form a dense web at the back of the eye inside the retina, as seen in 133 participants in a control group.

In the eyes of 39 people with Alzheimer’s disease, that web was less dense and even sparse in places. The differences in density were statistically significant after researchers controlled for factors including age, sex, and level of education, said Duke ophthalmologist and retinal surgeon Sharon Fekrat, MD, the study’s senior author.

“We’re measuring blood vessels that can’t be seen during a regular eye exam and we’re doing that with relatively new noninvasive technology that takes high-resolution images of very small blood vessels within the retina in just a few minutes,” she said. “It’s possible that these changes in blood vessel density in the retina could mirror what’s going on in the tiny blood vessels in the brain, perhaps before we are able to detect any changes in cognition.” 

Read the full news item from Duke Eye Center here

Related News: Feature Story, Neuro-Ophthalmology, Retina Disorders , Top Story

rpb logo

Research to Prevent Blindness and American Academy of Ophthalmology Award Grants for Big Data Research to Improve Patient Care

Award recipients to use IRIS Registry database to improve diagnosis and treatment of eye disease

Read More

 
RPB logo

Research to Prevent Blindness and Association of University Professors of Ophthalmology Announce 2022 Recipient of RPB David F. Weeks Award for Outstanding Vision Research

Donald Zack, MD, PhD, is recognized for ground-breaking contributions to the field of vision research.

Read More

 
William vanden Heuvel

In Memoriam: William J. vanden Heuvel

The RPB Board Member, who was a U.S. Ambassador, lawyer, and champion of human rights, worked tirelessly for causes he believed in.

Read More

 
Photo of eye
Watch The Video

RPB HOSTS VIRTUAL EVENT ON LOW VISION

The online event featured RPB grantees and is now available to view on demand.

Read More

 
RPB logo

Research to Prevent Blindness and The Glaucoma Foundation Offer Critical Funding for Early-Career Vision Scientists

The Career Advancement Awards—one focused specifically on glaucoma research—support novel science related to eye diseases by up-and-coming researchers.

Read More

 
Event photo
Watch The Video

RPB Hosts Virtual Event On Diabetic Retinopathy

RPB grantees provide expert advice on DR as part of the "Lunch & Learn" series.

Read More

 

Subscribe

Get our email updates filled with the latest news from our researchers about preventing vision loss, treating eye disease and even restoring sight. Unsubscribe at any time. Under our privacy policy, we'll never share your contact information with a third party.