Research to Prevent Blindness

2017 New Research

December, 2017
November, 2017
October, 2017
September, 2017
August, 2017
July, 2017
June, 2017
May, 2017
April, 2017
March, 2017
February, 2017
January, 2017

December, 2017

AAV2-Mediated Transduction of the Mouse Retina after Optic Nerve Injury

Robert W. Nickells, Heather M. Schmitt, Margaret E. Maes, Cassandra L. Schlamp
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6091-6104

Accuracy of Diagnostic Imaging Modalities for Classifying Pediatric Eyes as Papilledema Versus Pseudopapilledema

Chang, Melinda Y. et al.
Ophthalmology, Volume 124, Issue 12, 1839 – 1848

Changes in Relative Position of Choroidal Versus Retinal Vessels in Preterm Infants

Sang Jin Kim, J. Peter Campbell, Susan Ostmo, Karyn E. Jonas, R. V. Paul Chan, Michael F. Chiang, for the Imaging and Informatics in Retinopathy of Prematurity (i-ROP) Research Consortium
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6334-6341

Clinical and Morphologic Characteristics of MEK Inhibitor–Associated Retinopathy

Francis, Jasmine H. et al.
Ophthalmology, Volume 124, Issue 12, 1788 – 1798

Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field

Zhang, Xinbo et al.
American Journal of Ophthalmology, Volume 184, 63 – 74

Crosstalk between Histone and DNA Methylation in Regulation of Retinal Matrix Metalloproteinase-9 in Diabetes

Arul J. Duraisamy, Manish Mishra, Renu A. Kowluru
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6440-6448

Detecting Visual Field Progression

Aref, Ahmad A. et al.
Ophthalmology, Volume 124, Issue 12, S51 - S56

Generational Differences in the 5-Year Incidence of Age-Related Macular Degeneration

Cruickshanks KJ, Nondahl DM, Johnson LJ, et al.
JAMA Ophthalmol 2017;135(12):1417–1423

Germ-line and somatic EPHA2 coding variants in lens aging and cataract

Bennett TM, M’Hamdi O, Hejtmancik JF, Shiels A
PLOS ONE 12(12): e0189881

Higher Contrast Requirement for Letter Recognition and Macular RGC+ Layer Thinning in Glaucoma Patients and Older Adults

Lillian Chien, Rong Liu, Christopher Girkin, MiYoung Kwon
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6221-6231

Macular Atrophy Development and Subretinal Drusenoid Deposits in Anti-Vascular Endothelial Growth Factor Treated Age-Related Macular Degeneration

Anna V. Zarubina, Orly Gal-Or, Carrie E. Huisingh, Cynthia Owsley, K. Bailey Freund
Invest. Ophthalmol. Vis. Sci.2017;58(14):6038-6045

Macular Fluid Reduces Reproducibility of Choroidal Thickness Measurements on Enhanced Depth Optical Coherence Tomography

Wong, Sophia S. et al.
American Journal of Ophthalmology, Volume 184, 108 – 114

Micro- and Nanoscale Topographies on Silk Regulate Gene Expression of Human Corneal Epithelial Cells

Kai B. Kang, Brian D. Lawrence, X. Raymond Gao, Yuncin Luo, Qiang Zhou, Aihong Liu, Victor H. Guaiquil, Mark I. Rosenblatt
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6388-6398

PI3K/Akt Pathway: A Role in δ-Opioid Receptor–Mediated RGC Neuroprotection

Shahid Husain, Anis Ahmad, Sudha Singh, Carolyn Peterseim, Yasir Abdul, Matthew J. Nutaitis
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6489-6499

Prevalence and Associations of Central-Peripheral Rivalry–Type Diplopia in Patients with Epiretinal Membrane

Veverka KK, Hatt SR, Leske DA, et al.
JAMA Ophthalmol. 2017;135(12):1303–1309

Quantitative Autofluorescence Intensities in Acute Zonal Occult Outer Retinopathy vs Healthy Eyes

Boudreault K, Schuerch K, Zhao J, et al.
JAMA Ophthalmol. 2017;135(12):1330–1338

Risk of Extraocular Extension in Eyes with Retinoblastoma Receiving Intravitreous Chemotherapy

Francis JH, Abramson DH, Ji X, et al.
JAMA Ophthalmol. 2017;135(12):1426–1429

RNA-Sequencing Gene Expression Profiling of Orbital Adipose-Derived Stem Cell Population Implicate HOX Genes and WNT Signaling Dysregulation in the Pathogenesis of Thyroid-Associated Orbitopathy

Wensi Tao, Juan A. Ayala-Haedo, Matthew G. Field, Daniel Pelaez, Sara T. Wester
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6146-6158

Skin Intrinsic Fluorescence and Age-Related Macular Degeneration: The Beaver Dam Eye Study

Ronald Klein, Kristine E. Lee, John D. Maynard, Stacy M. Meuer, Ronald E. Gangnon, Barbara E. K. Klein
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6328-6333

Tear Levels of Insulin-Like Growth Factor Binding Protein 3 Correlate with Subbasal Nerve Plexus Changes in Patients with Type 2 Diabetes Mellitus

Whitney L. Stuard, Rossella Titone, Danielle M. Robertson
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6105-6112

The Challenge of Detecting Glaucoma Progression

Tanna, Angelo P.
Ophthalmology, Volume 124, Issue 12, S49 - S50

The Magnitude and Time Course of IOP Change in Response to Body Position change in Nonhuman Primates Measured using Continuous IOP Telemetry

Daniel C. Turner, Brian C. Samuels, Carrie Huisingh, Christopher A. Girkin, J. Crawford Downs
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6232-6240

Toward the Miracle of Retinal Reanimation

Van Gelder, Russell N.
Ophthalmology, Volume 124, Issue 12, 1723 – 1725

Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1, 25(OH)2D3

Jamali N, Wang S, Darjatmoko SR, Sorenson CM, Sheibani N
PLOS ONE 12(12): e0190131

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November, 2017

Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy with Existing Ocular Hypotensive Agents

Uttio Roy Chowdhury, Tommy A. Rinkoski, Cindy K. Bahler, J. Cameron Millar, Jacques A. Bertrand, Bradley H. Holman, Joseph M. Sherwood, Darryl R. Overby, Kristen L. Stoltz, Peter I. Dosa, Michael P. Fautsch
Invest. Ophthalmol. Vis. Sci. 2017;58(13):5731-5742

Gene Therapy for Leber Hereditary Optic Neuropathy

Guy, John et al.
Ophthalmology, Volume 124, Issue 11, 1621 – 1634

In-vivo effects of intraocular and intracranial pressures on the lamina cribrosa microstructure

Wang B, Tran H, Smith MA, Kostanyan T, Schmitt SE, et al.
PLOS ONE 12(11): e0188302

Mast Cell-Derived Tryptase in Geographic Atrophy

D. Scott McLeod, Imran Bhutto, Malia M. Edwards, Manasee Gedam, Rajkumar Baldeosingh, Gerard A. Lutty
Invest. Ophthalmol. Vis. Sci. 2017;58(13):5887-5896

Myopic Choroidal Neovascularization

Cheung, Chui Ming Gemmy et al.
Ophthalmology, Volume 124, Issue 11, 1690 – 1711

Ocular Histopathologic Features of Congenital Zika Syndrome

Maria P. Fernandez, Edgar Parra Saad, Martha Ospina Martinez, Sheryl Corchuelo, Marcela Mercado Reyes, Maria Jose Herrera, Miguel Parra Saavedra, Angelica Rico, Angela M. Fernandez, Richard K. Lee, Camila V. Ventura, Audina M. Berrocal, Sander R. Dubovy
JAMA Ophthalmol. 2017;135(11):1163–1169

Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma

Jesse L. Berry, Liya Xu, A. Linn Murphree, Subramanian Krishnan, Kevin Stachelek, Emily Zolfaghari, Kathleen McGovern, Thomas C. Lee, Anders Carlsson, Peter Kuhn, Jonathan W. Kim, David Cobrinik, James Hicks
JAMA Ophthalmol. 2017;135(11):1221–1230

Progression of Stargardt Disease as Determined by Fundus Autofluorescence in the Retrospective Progression of Stargardt Disease Study (ProgStar Report No. 9)

Rupert W. Strauss, Beatriz Muñoz, Alexander Ho, Anamika Jha, Michel Michaelides, Artur V. Cideciyan, Isabelle Audo, David G. Birch, Amir H. Hariri, Muneeswar G. Nittala, SriniVas Sadda, Sheila West, Hendrik P. N. Scholl
JAMA Ophthalmol.2017;135(11):1232–1241

Projection-Resolved Optical Coherence Tomography Angiography of Macular Retinal Circulation in Glaucoma

Takusagawa, Hana L. et al.
Ophthalmology, Volume 124, Issue 11, 1589 – 1599

Retinal Vascular and Oxygen Temporal Dynamic Responses to Light Flicker in Humans

Anthony E. Felder, Justin Wanek, Norman P. Blair, Mahnaz Shahidi
Invest. Ophthalmol. Vis. Sci. 2017;58(13):5666-5672

Slow Reading in Glaucoma: Is it due to the Shrinking Visual Span in Central Vision?

MiYoung Kwon, Rong Liu, Bhavika N. Patel, Christopher Girkin
Invest. Ophthalmol. Vis. Sci. 2017;58(13):5810-5818

The Effect of Pulsing on Transverse Ultrasound Efficiency and Chatter

Wright, Alex J. et al.
American Journal of Ophthalmology, Volume 183, 107 – 110

The Relationship between High-Order Aberration and Anterior Ocular Biometry During Accommodation in Young Healthy Adults

Bilian Ke, Xinjie Mao, Hong Jiang, Jichang He, Che Liu, Min Li, Ying Yuan, Jianhua Wang
Invest. Ophthalmol. Vis. Sci. 2017;58(13):5628-5635

Time Requirements for Electronic Health Record use in an Academic Ophthalmology Center

Sarah Read-Brown, Michelle R. Hribar, Leah G. Reznick, Lorinna H. Lombardi, Mansi Parikh, Winston D. Chamberlain, Steven T. Bailey, Jessica B. Wallace, Thomas R. Yackel, Michael F. Chiang
JAMA Ophthalmol.2017;135(11):1250–1257

Treatment with solubilized Silk-Derived Protein (SDP) enhances rabbit corneal epithelial wound healing

Abdel-Naby W, Cole B, Liu A, Liu J, Wan P, et al.
PLOS ONE 12(11): e0188154

Update on the Management of Infectious Keratitis

Austin, Ariana et al.
Ophthalmology, Volume 124, Issue 11, 1678 – 1689

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October, 2017

24-2 Visual Fields Miss Central Defects Shown on 10-2 Tests in Glaucoma Suspects, Ocular Hypertensives, and Early Glaucoma

De Moraes, C. Gustavo et al.
Ophthalmology, Volume 124, Issue 10, 1449 – 1456

A Comparison of En Face Optical Coherence Tomography and Fundus Autofluorescence in Stargardt Disease

Vivienne C. Greenstein, Jason Nunez, Winston Lee, Kaspar Schuerch, Brad Fortune, Stephen H. Tsang, Rando Allikmets, Janet R. Sparrow, Donald C. Hood
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5227-5236

Assessment of Neurotrophins and Inflammatory Mediators in Vitreous of Patients with Diabetic Retinopathy

Joseph D. Boss, Pawan Kumar Singh, Hemang K. Pandya, Joaquin Tosi, Chaesik Kim, Asheesh Tewari, Mark S. Juzych, Gary W. Abrams, Ashok Kumar
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5594-5603

Association between Tumor Regression Rate and Gene Expression Profile after Iodine 125 Plaque Radiotherapy for Uveal Melanoma

Mruthyunjaya, PrithviMruthyunjaya, Prithvi et al.
Ophthalmology, Volume 124, Issue 10, 1532 – 1539

Comparison of Neovascular Lesion Area Measurements from Different Swept-Source OCT Angiographic Scan Patterns in Age-Related Macular Degeneration

Fang Zheng, Qinqin Zhang, Elie H. Motulsky, João Rafael de Oliveira Dias, Chieh-Li Chen, Zhongdi Chu, Andrew R. Miller, William Feuer, Giovanni Gregori, Sophie Kubach, Mary K. Durbin, Ruikang K. Wang, Philip J. Rosenfeld
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5098-5104

Corneal Mesenchymal Stromal Cells are Directly Antiangiogenic via PEDF and sFLT-1

Medi Eslani, Ilham Putra, Xiang Shen, Judy Hamouie, Neda Afsharkhamseh, Soroush Besharat, Mark I. Rosenblatt, Reza Dana, Peiman Hematti, Ali R. Djalilian
Invest. Ophthalmol. Vis. Sci.2017;58(12):5507-5517

Development and Evaluation of Semiautomated Quantification of Lissamine Green Staining of the Bulbar Conjunctiva from Digital Images

Vatinee Y. Bunya, Min Chen, Yuanjie Zheng, Mina Massaro-Giordano, James Gee, Ebenezer Daniel, Ryan O'Sullivan, Eli Smith, Richard A. Stone, Maureen G. Maguire
JAMA Ophthalmol. 2017;135(10):1078–1085

Effect of Body Position on Epsicleral Venous Pressure in Healthy Subjects

Nitika Arora, Jay W. McLaren, David O. Hodge, Arthur J. Sit
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5151-5156

Foveal and Peripapillary Vascular Decrement in Migraine with Aura Demonstrated by Optical Coherence Tomography Angiography

Melinda Y. Chang, Nopasak Phasukkijwatana, Sean Garrity, Stacy L. Pineles, Mansour Rahimi, David Sarraf, Mollie Johnston, Andrew Charles, Anthony C. Arnold
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5477-5484

Fully-automated segmentation of fluid regions in exudative age-related macular degeneration subjects: Kernel graph cut in neutrosophic domain

Rashno A, Nazari B, Koozekanani DD, Drayna PM, Sadri S, et al.
PLOS ONE 12(10): e0186949

Human Adipose-Derived Stem Cells Support the Growth of Limbal Stem/Progenitor Cells

Mei H, González S, Nakatsu MN, Baclagon ER, Chen FV, et al. PLOS ONE 12(10): e0186238

Imaging Lenticular Autofluorescence in Older Subjects

Jason Charng, Rose Tan, Chi D. Luu, Sam Sadigh, Dwight Stambolian, Robyn H. Guymer, Samuel G. Jacobson, Artur V. Cideciyan
Invest. Ophthalmol. Vis. Sci. 2017;58(12):4940-4947

Impact of Myopia on Corneal Biomechanics in Glaucoma and Nonglaucoma Patients

Sunee Chansangpetch, Rawiphan Panpruk, Anita Manassakorn, Visanee Tantisevi, Prin Rojanapongpun, Cameron P. Hurst, Shan C. Lin
Invest. Ophthalmol. Vis. Sci. 2017;58(12):4990-4996

Incidence and Types of Pediatric Nystagmus

Nash, David L. et al.
American Journal of Ophthalmology, Volume 182, 31 – 34

Incomitance and Eye Dominance in Intermittent Exotropia

Daniel L. Adams, John R. Economides, Jonathan C. Horton
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4049-4055

Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina

Ping Hu, Nicholas H. Hunt, Frank Arfuso, Lynn C. Shaw, Mohammad Nasir Uddin, Meidong Zhu, Raj Devasahayam, Samuel J. Adamson, Vicky L. Benson, Tailoi Chan-Ling, Maria B. Grant
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5043-5055

Optical Coherence Tomography Angiography of the Peripapillary Retina in Primary Angle-Closure Glaucoma

Zhang, Shunhua et al.
American Journal of Ophthalmology, Volume 182, 194 – 200

Pattern Recognition Analysis Reveals Unique Contrast Sensitivity Isocontours using Static Perimetry Thresholds Across the Visual Field

Jack Phu, Sieu K. Khuu, Lisa Nivison-Smith, Barbara Zangerl, Agnes Yiu Jeung Choi, Bryan W. Jones, Rebecca L. Pfeiffer, Robert E. Marc, Michael Kalloniatis
Invest. Ophthalmol. Vis. Sci. 2017;58(11):4863-4876

Performance of an iPad Application to Detect Moderate and Advanced Visual Field Loss in Nepal

Johnson, Chris A. et al.
American Journal of Ophthalmology, Volume 182, 147 – 154

Progressive Deformation of the Optic Nerve Head and Peripapillary Structures by Graded Horizontal Duction

Soh Youn Suh, Alan Le, Andrew Shin, Joseph Park, Joseph L. Demer
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5015-5021

Progressive Macula Vessel Density Loss in Primary Open-Angle Glaucoma: A Longitudinal Study

Shoji, Takuhei et al.
American Journal of Ophthalmology, Volume 182, 107 – 117

Quantifying Microvascular Abnormalities with Increasing Severity of Diabetic Retinopathy using Optical Coherence Tomography Angiography

Peter L. Nesper, Philipp K. Roberts, Alex C. Onishi, Haitao Chai, Lei Liu, Lee M. Jampol, Amani A. Fawzi; Invest. Ophthalmol. Vis. Sci. 2017;58(6):BIO307-BIO315

Retinal Oximetry and Vessel Diameter Measurements with a Commercially Available Scanning Laser Ophthalmoscope in Diabetic Retinopathy

Norman P. Blair, Justin Wanek, Anthony E. Felder, Charlotte E. Joslin, Jacob K. Kresovich, Jennifer I. Lim, Felix Y. Chau, Yannek Leiderman, Mahnaz Shahidi
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5556-5563

Retinoblastoma Vitreous Seed Clouds (Class 3)

Francis, Jasmine H. et al.
Ophthalmology, Volume 124, Issue 10, 1548 – 1555

Spectral-Domain Optical Coherence Tomographic Angiography in Children with Amblyopia

Marcela Lonngi, Federico G. Velez, Irena Tsui, Juan Pablo Davila, Mansour Rahimi, Clarissa Chan, David Sarraf, Joseph L. Demer, Stacy L. Pineles
JAMA Ophthalmol. 2017;135(10):1086–1091

Strabismus Incidence in a Danish Population-Based Cohort of Children

Tobias Torp-Pedersen, Heather A. Boyd, Line Skotte, Birgitte Haargaard, Jan Wohlfahrt, Jonathan M. Holmes, Mads Melbye
JAMA Ophthalmol. 2017;135(10):1047–1053

Surgically Induced Focal Retinal Detachment Does Not Cause Detectable SD-OCT Retinal Changes in Normal Human Retina

Kaitlin Kogachi, Jeremy D. Wolfe, Amir H. Kashani
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5270-5279

Sustaining Intravitreal Residence with L-Arginine Peptide-Conjugated Nanocarriers

Hao Li, Wenzhong Liu, Christine M. Sorenson, Nader Sheibani, Daniel M. Albert, Thulani Senanayake, Serguei Vinogradov, Jack Henkin, Hao F. Zhang
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5142-5150

The 2017 US Preventive Services Task Force Report on Preschool Vision Screening

Sean P. Donahue
JAMA Ophthalmol. 2017;135(10):1021–1022

The Nine-Step Minnesota Grading System for Eyebank Eyes with Age Related Macular Degeneration: A Systematic Approach to Study Disease Stages

Timothy W. Olsen, Albert Liao, Hershonna S. Robinson, Neal V. Palejwala, Nicholas Sprehe
Invest. Ophthalmol. Vis. Sci.2017;58(12):5497-5506

The Riddle of Intermittent Exotropia

Michael C. Brodsky
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4056

The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina

Sergio Groman-Lupa, Joseph Adewumi, Ko Uoon Park, Joseph A. Brzezinski IV
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5421-5433

Tunneling Nanotubes are Novel Cellular Structures that Communicate Signals between Trabecular Meshwork Cells

Kate E. Keller, John M. Bradley, Ying Ying Sun, Yong-Feng Yang, Ted S. Acott
Invest. Ophthalmol. Vis. Sci. 2017;58(12):5298-5307

Wide-Field OCT Angiography Investigation of the Relationship between Radial Peripapillary Capillary Plexus Density and Nerve Fiber Layer Thickness

Yali Jia, Joseph M. Simonett, Jie Wang, Xiaohui Hua, Liang Liu, Thomas S. Hwang, David Huang
Invest. Ophthalmol. Vis. Sci.2017;58(12):5188-5194

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September, 2017

Association of Vision Loss With Cognition in Older Adults

Stephanie P. Chen, Jay Bhattacharya, Suzann Pershing
JAMA Ophthalmol. 2017;135(9):963–970

Colony Stimulating Factor-1 Receptor Expressing Cells Infiltrating the Cornea Control Corneal Nerve Degeneration in Response to HSV-1 Infection

Ana J. Chucair-Elliott, Hem R. Gurung, Meghan M. Carr, Daniel J. J. Carr
Invest. Ophthalmol. Vis. Sci. 2017;58(11):4670-4682

Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

Philip A. Ruzycki, Courtney D. Linne, Anne K. Hennig, Shiming Chen
Invest. Ophthalmol. Vis. Sci. 2017;58(11):4644-4653

Fuchs' Endothelial Corneal Dystrophy and RNA Foci in Patients with Myotonic Dystrophy

V. Vinod Mootha, Brock Hansen, Ziye Rong, Pradeep P. Mammen, Zhengyang Zhou, Chao Xing, Xin Gong
Invest. Ophthalmol. Vis. Sci. 2017;58(11):4579-4585

Handheld Optical Coherence Tomography Angiography and Ultra–Wide-Field Optical Coherence Tomography in Retinopathy of Prematurity

J. Peter Campbell, Eric Nudleman, Jianlong Yang, Ou Tan, R. V. Paul Chan, Michael F. Chiang, David Huang, Gangjun Liu
JAMA Ophthalmol. 2017;135(9):977–981

Hypoxia-Inducible Factor-Dependent Expression of Angiopoietin-Like 4 by Conjunctival Epithelial Cells Promotes the Angiogenic Phenotype of Pterygia

Qianli Meng, Yaowu Qin, Monika Deshpande, Fabiana Kashiwabuchi, Murilo Rodrigues, Qiaozhi Lu, Hui Ren, Jennifer H. Elisseeff, Gregg L. Semenza, Silvia V. Montaner, Akrit Sodhi
Invest. Ophthalmol. Vis. Sci. 2017;58(11):4514-4523

Impact of Normal Aging and Progression Definitions on the Specificity of Detecting Retinal Nerve Fiber Layer Thinning

Wu, Zhichao et al.
American Journal of Ophthalmology , Volume 181 , 106 - 113

Intraretinal Correlates of Reticular Pseudodrusen Revealed by Autofluorescence and En Face OCT

Maarjaliis Paavo, Winston Lee, John Merriam, Srilaxmi Bearelly, Stephen Tsang, Stanley Chang, Janet R. Sparrow
Invest. Ophthalmol. Vis. Sci. 2017;58(11):4769-4777

Light entrainment of the murine intraocular pressure circadian rhythm utilizes non-local mechanisms

Tsuchiya S, Buhr ED, Higashide T, Sugiyama K, Van Gelder RN
PLOS ONE 12(9): e0184790

Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis

Maes ME, Schlamp CL, Nickells RW
PLOS ONE 12(9): e0184434

Metrics and Acquisition Modes for Fixation Stability as a Visual Function Biomarker

Etienne M. Schönbach, Mohamed A. Ibrahim, Xiangrong Kong, Rupert W. Strauss, Beatriz Muñoz, David G. Birch, Janet S. Sunness, Sheila K. West, Hendrik P. N. Scholl
Invest. Ophthalmol. Vis. Sci.2017;58(6):BIO268-BIO276

Multidimensional Functional and Structural Evaluation Reveals Neuroretinal Impairment in Early Diabetic Retinopathy

Katherine A. Joltikov, Vinicius M. de Castro, Jose R. Davila, Rohit Anand, Sami M. Khan, Neil Farbman, Gregory R. Jackson, Chris A. Johnson, Thomas W. Gardner
Invest. Ophthalmol. Vis. Sci. 2017;58(6):BIO277-BIO290

Peptide Nucleic Acid–Fluorescence In Situ Hybridization for Detection of Staphylococci From Endophthalmitis Isolates: A Proof-of-Concept Study

Nimesh Patel, Darlene Miller, Nidhi Relhan, Harry W. Flynn 
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4307-4309

Philadelphia Telemedicine Glaucoma Detection and Follow-up Study: Methods and Screening Results

Hark, Lisa A. et al.
American Journal of Ophthalmology , Volume 181 , 114 - 124

Photoreceptor-Based Biomarkers in AOSLO Retinal Imaging

Katie M. Litts, Robert F. Cooper, Jacque L. Duncan, Joseph Carroll
Invest. Ophthalmol. Vis. Sci. 2017;58(6):BIO255-BIO267

Predictors of Corneal Perforation or Need for Therapeutic Keratoplasty in Severe Fungal KeratitisA Secondary Analysis of the Mycotic Ulcer Treatment Trial II

N. Venkatesh Prajna, Tiruvengada Krishnan, Revathi Rajaraman, Sushila Patel, Ranjeet Shah, Muthiah Srinivasan, Manoranjan Das, Kathryn J. Ray, Catherine E. Oldenburg, Stephen D. McLeod, Michael E. Zegans, Nisha R. Acharya, Thomas M. Lietman, Jennifer Rose-Nussbaumer
JAMA Ophthalmol. 2017;135(9):987–991

Rates of Local Retinal Nerve Fiber Layer Thinning before and after Disc Hemorrhage in Glaucoma

Akagi, Tadamichi et al.
Ophthalmology , Volume 124 , Issue 9 , 1403 - 1411

Retinal thinning in amyotrophic lateral sclerosis patients without ophthalmic disease

Mukherjee N, McBurney-Lin S, Kuo A, Bedlack R, Tseng H
PLOS ONE 12(9): e0185242

Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas

Chelsea L. Loughner, Anil Tiwari, Doreswamy Kenchegowda, Sudha Swamynathan, Shivalingappa K. Swamynathan
Invest. Ophthalmol. Vis. Sci.2017;58(11):4683-4693

Structural Changes Associated with Delayed Dark Adaptation in Age-Related Macular Degeneration

Laíns, Inês et al.
Ophthalmology , Volume 124 , Issue 9 , 1340 - 1352

Structure-Function Relationships in Perimetric Glaucoma: Comparison of Minimum-Rim Width and Retinal Nerve Fiber Layer Parameters

Navid Amini, Ramin Daneshvar, Farideh Sharifipour, Pablo Romero, Sharon Henry, Joseph Caprioli, Kouros Nouri-Mahdavi
Invest. Ophthalmol. Vis. Sci. 2017;58(11):4623-4631

The effect of electronic health record software design on resident documentation and compliance with evidence-based medicine

Rodriguez Torres Y, Huang J, Mihlstin M, Juzych MS, Kromrei H, et al.
PLOS ONE 12(9): e0185052

The Evolution of Outer Retinal Tubulation, a Neurodegeneration and Gliosis Prominent in Macular Diseases

Dolz-Marco, Rosa et al.
Ophthalmology , Volume 124 , Issue 9 , 1353 - 1367

Vertical Macular Asymmetry Measures Derived From SD-OCT for Detection of Early Glaucoma

Farideh Sharifipour, Esteban Morales, Ji Woong Lee, JoAnn Giaconi, Abdelmonem A. Afifi, Fei Yu, Joseph Caprioli, Kouros Nouri-Mahdavi
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4310-4317

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August, 2017

Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration

Christine A. Curcio, Emma C. Zanzottera, Thomas Ach, Chandrakumar Balaratnasingam, K. Bailey Freund
Invest. Ophthalmol. Vis. Sci.2017;58(6):BIO211-BIO226

Age-Related Alterations in the Retinal Microvasculature, Microcirculation, and Microstructure

Yantao Wei, Hong Jiang, Yingying Shi, Dongyi Qu, Giovanni Gregori, Fang Zheng, Tatjana Rundek, Jianhua Wang
Invest. Ophthalmol. Vis. Sci. 2017;58(9):3804-3817

Characterization of a variant of gap junction protein ?8 identified in a family with hereditary cataract

Kuo DS, Sokol JT, Minogue PJ, Berthoud VM, Slavotinek AM, et al.
PLOS ONE 12(8): e0183438

Characterization of lincRNA expression in the human retinal pigment epithelium and differentiated induced pluripotent stem cells

Au ED, Fernandez-Godino R, Kaczynksi TJ, Sousa ME, Farkas MH
PLOS ONE 12(8): e0183939

Chondroitin Sulfate–Based Biocompatible Crosslinker Restores Corneal Mechanics and Collagen Alignment

Xiaokun Wang, Shoumyo Majumdar, Garret Ma, Jeeyeon Sohn, Samuel C. Yiu, Walter Stark, Awad Al-Qarni, Deepak P. Edward, Jennifer H. Elisseeff
Invest. Ophthalmol. Vis. Sci. 2017;58(10):3887-3895

Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina

Mills TS, Eliseeva T, Bersie SM, Randazzo G, Nahreini J, et al.
PLOS ONE 12(8): e0176905

Conditional, Genetically Encoded, Small Molecule–Regulated Inhibition of NF?B Signaling in RPE Cells

Khiem T. Vu, Fang Zhang, John D. Hulleman
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4126-4137

Conditional Müller Cell Ablation Leads to Retinal Iron Accumulation

Bailey Baumann, Jacob Sterling, Ying Song, Delu Song, Marcus Fruttiger, Mark Gillies, Weiyong Shen, Joshua L. Dunaief
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4223-4234

Disparities in delivery of ophthalmic care; An exploration of public Medicare data

Lee CS, Su GL, Baughman DM, Wu Y, Lee AY
PLOS ONE 12(8): e0182598

Effects of Vitrectomy and Lensectomy on Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, and Aqueous Humor Dynamics

Carla J. Siegfried, Ying-Bo Shui, Baohe Tian, T. Michael Nork, Gregg A. Heatley, Paul L. Kaufman
Invest. Ophthalmol. Vis. Sci.2017;58(10):4003-4014

Evaluating Structural Progression of Retinitis Pigmentosa After Cataract Surgery

De Rojas, Joaquin O. et al.
American Journal of Ophthalmology , Volume 180 , 117 - 123

Evaluation of Femtosecond Laser Intrastromal Incision Location Using Optical Coherence Tomography

Wang, Li et al.
Ophthalmology , Volume 124 , Issue 8 , 1120 - 1125

Evaluation of Therapeutic Tissue Crosslinking (TXL) for Myopia using Second Harmonic Generation Signal Microscopy in Rabbit Sclera

Mariya Zyablitskaya, Anna Takaoka, Emilia L. Munteanu, Takayuki Nagasaki, Stephen L. Trokel, David C. Paik
Invest. Ophthalmol. Vis. Sci.2017;58(1):21-29

Expression of the angiogenic mediator, angiopoietin-like 4, in the eyes of patients with proliferative sickle retinopathy

Jee K, Rodrigues M, Kashiwabuchi F, Applewhite BP, Han I, et al.
PLOS ONE 12(8): e0183320

Fundus Autofluorescence Findings in Eyes with Birdshot Chorioretinitis

Christian Böni, Jennifer E. Thorne, Richard F. Spaide, Trucian A. Ostheimer, David Sarraf, Ralph D. Levinson, Debra A. Goldstein, Lana M. Rifkin, Albert T. Vitale, Glenn J. Jaffe, Gary N. Holland
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4015-4025

Magnetic Resonance Imaging of Optic Nerve Traction During Adduction in Primary Open-Angle Glaucoma with Normal Intraocular Pressure

Joseph L. Demer, Robert A. Clark, Soh Youn Suh, JoAnn A. Giaconi, Kouros Nouri-Mahdavi, Simon K. Law, Laura Bonelli, Anne L. Coleman, Joseph Caprioli
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4114-4125

Mouse models of human ocular disease for translational research

Krebs MP, Collin GB, Hicks WL, Yu M, Charette JR, et al.
PLOS ONE 12(8): e0183837

Oxidative Stress–Related Molecular Biomarker Candidates for Glaucoma

Gözde Hondur, Emre Gökta?, Xiangjun Yang, Lama Al-Aswad, James D. Auran, Dana M. Blumberg, George A. Cioffi, Jeffrey M. Liebmann, Leejee H. Suh, Danielle Trief, Gülgün Tezel
Invest. Ophthalmol. Vis. Sci. 2017;58(10):4078-4088

Peripapillary retinal splitting visualized on OCT in glaucoma and glaucoma suspect patients

Grewal DS, Merlau DJ, Giri P, Munk MR, Fawzi AA, et al.
PLOS ONE 12(8): e0182816

Physical Activity and Age-related Macular Degeneration: A Systematic Literature Review and Meta-analysis

McGuinness, Myra B. et al.
American Journal of Ophthalmology , Volume 180 , 29 - 38

Population activity structure of excitatory and inhibitory neurons

Bittner SR, Williamson RC, Snyder AC, Litwin-Kumar A, Doiron B, et al.
PLOS ONE 12(8): e0181773

Protective effect of clusterin on rod photoreceptor in rat model of retinitis pigmentosa

Vargas A, Kim HS, Baral E, Yu WQ, Craft CM, et al.
PLOS ONE 12(8): e0182389

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July, 2017

Analysis of Retinal Architectural Changes Using Intraoperative OCT Following Surgical Manipulations With Membrane Flex Loop in the DISCOVER Study

Atsuro Uchida, Sunil K. Srivastava, Justis P. Ehlers
Invest. Ophthalmol. Vis. Sci. 2017;58(9):3440-3444

A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs

Jeffrey Tran, Caroline Craven, Kathy Wabner, Jenn Schmit, Brock Matter, Uday Kompella, Hans E. Grossniklaus, Timothy W. Olsen
Invest. Ophthalmol. Vis. Sci.2017;58(9):3732-3740

Assessment of a Tele-education System to Enhance Retinopathy of Prematurity Training by International Ophthalmologists-in-Training in Mexico

Patel, Samir N.Chan, R.V. PaulChiang, Michael F. et al.
Ophthalmology, Volume 124, Issue 7, 953 – 961

Association Between Undetected 10-2 Visual Field Damage and Vision-Related Quality of Life in Patients with Glaucoma

Dana M. Blumberg, Carlos Gustavo De Moraes, Alisa J. Prager, Qi Yu, Lama Al-Aswad, George A. Cioffi, Jeffrey M. Liebmann, Donald C. Hood
JAMA Ophthalmol. 2017;135(7):742–747

Association of Glaucoma-Related, Optical Coherence Tomography–Measured Macular Damage With Vision-Related Quality of Life

Alisa J. Prager, Donald C. Hood, Jeffrey M. Liebmann, C. Gustavo De Moraes, Lama A. Al-Aswad, Qi Yu, George A. Cioffi, Dana M. Blumberg
JAMA Ophthalmol. 2017;135(7):783–788

Causes of Diplopia in Patients With Epiretinal Membranes

Veverka, Kevin K. et al.
American Journal of Ophthalmology, Volume 179, 39 – 45

Comparison of Alternative Tumor Size Classifications for Posterior Uveal Melanomas

Cassandra C. Skinner, James J. Augsburger, Bret D. Augsburger, Zelia M. Correa
Invest. Ophthalmol. Vis. Sci. 2017;58(9):3335-3342

Correlations Between Macular, Skin, and Serum Carotenoids

Christopher D. Conrady, James P. Bell, Brian M. Besch, Aruna Gorusupudi, Kelliann Farnsworth, Igor Ermakov, Mohsen Sharifzadeh, Maia Ermakova, Werner Gellermann, Paul S. Bernstein
Invest. Ophthalmol. Vis. Sci.2017;58(9):3616-3627

De novo assembly and annotation of the retinal transcriptome for the Nile grass rat (Arvicanthis ansorgei)

Liu MM, Farkas M, Spinnhirny P, Pevet P, Pierce E, et al.
PLOS ONE 12(7): e017906

Detailed Clinical Phenotype and Molecular Genetic Findings in CLN3-Associated Isolated Retinal Degeneration

Cristy A. Ku, Sarah Hull, Gavin Arno, Ajoy Vincent, Keren Carss, Robert Kayton, Douglas Weeks, Glenn W. Anderson, Ryan Geraets, Camille Parker, David A. Pearce, Michel Michaelides, Robert E. MacLaren, Anthony G. Robson, Graham E. Holder, Elise Heon, F. Lucy Raymond, Anthony T. Moore, Andrew R. Webster, Mark E. Pennesi
JAMA Ophthalmol. 2017;135(7):749–760

Effects of Pathogenic Variations in the Human Rhodopsin Gene (hRHO) on the Predicted Accessibility for a Lead Candidate Ribozyme

Beau R. Froebel, Alexandria J. Trujillo, Jack M. Sullivan
Invest. Ophthalmol. Vis. Sci. 2017;58(9):3576-3591

Establishing a Regional Glaucoma Physician Collaborative to Improve Quality of Care

Ehrlich, Joshua R. et al.
American Journal of Ophthalmology, Volume 179, 145 – 150

Functional Reading Independence (FRI) Index: A New Patient-Reported Outcome Measure for Patients With Geographic Atrophy

Miriam Kimel, Nancy Kline Leidy, Elizabeth Tschosik, Chantal Dolan, Eric H. Souied, Rohit Varma, Neil M. Bressler
Invest. Ophthalmol. Vis. Sci.2017;57(14):6298-6304

Incidence of Atrophic Lesions in Stargardt Disease in the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) StudyReport No. 5

Rupert W. Strauss, Beatriz Muñoz, Alex Ho, Anamika Jha, Michel Michaelides, Saddek Mohand-Said, Artur V. Cideciyan, David Birch, Amir H. Hariri, Muneeswar G. Nittala, SriniVas Sadda, Hendrik P. N. Scholl
JAMA Ophthalmol. 2017;135(7):687–695

In Vivo Imaging of Retinal Hypoxia Using HYPOX-4-Dependent Fluorescence in a Mouse Model of Laser-Induced Retinal Vein Occlusion (RVO)

Md. Imam Uddin, Ashwath Jayagopal, Gary W. McCollum, Rong Yang, John S. Penn
Invest. Ophthalmol. Vis. Sci. 2017;58(9):3818-3824

OCT Angiography and Ellipsoid Zone Mapping of Macular Telangiectasia Type 2 From the AVATAR Study

Anne P. Runkle, Peter K. Kaiser, Sunil K. Srivastava, Andrew P. Schachat, Jamie L. Reese, Justis P. Ehlers
Invest. Ophthalmol. Vis. Sci. 2017;58(9):3683-3689

Ocular Determinants of Refractive Error and Its Age- and Sex-Related Variations in the Chinese American Eye Study

Grace M. Richter, Mingwu Wang, Xuejuan Jiang, Shuang Wu, Dandan Wang, Mina Torres, Farzana Choudhury, Rohit Varma
JAMA Ophthalmol. 2017;135(7):724–732

Quality-of-Life Outcomes from a Randomized Clinical Trial Comparing Antimetabolites for Intermediate, Posterior, and Panuveitis

Niemeyer, Katherine M. et al.
American Journal of Ophthalmology, Volume 179, 10 – 17

Report From the NEI/FDA Endpoints Workshop on Age-Related Macular Degeneration and Inherited Retinal Diseases

Karl Csaky, Frederick Ferris, Emily Y. Chew, Prashant Nair, Janet K. Cheetham, Jacque L. Duncan Invest. Ophthalmol. Vis. Sci. 2017;58(9):3456-3463

Self-reported Receipt of Dilated Fundus Examinations Among Patients with Diabetes: Medicare Expenditure Panel Survey, 2002–2013

Tran, Elaine My Tien et al.
American Journal of Ophthalmology, Volume 179, 18 – 24

Structural and Functional Characterization of Human Stem-Cell-Derived Retinal Organoids by Live Imaging

Andrew W. Browne, Cosimo Arnesano, Narine Harutyunyan, Thien Khuu, Juan Carlos Martinez, Harvey A. Pollack, David S. Koos, Thomas C. Lee, Scott E. Fraser, Rex A. Moats, Jennifer G. Aparicio, David Cobrinik
Invest. Ophthalmol. Vis. Sci. 2017;58(9):3311-3318

Variation in the Three-Dimensional Histomorphometry of the Normal Human Optic Nerve Head With Age and Race: Lamina Cribrosa and Peripapillary Scleral Thickness and Position

Christopher A. Girkin, Massimo A. Fazio, Hongli Yang, Juan Reynaud, Claude F. Burgoyne, Brandon Smith, Lan Wang, J. Crawford Downs
Invest. Ophthalmol. Vis. Sci. 2017;58(9):3759-3769

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June, 2017

Adjunctive Oral Voriconazole Treatment of Fusarium KeratitisA Secondary Analysis From the Mycotic Ulcer Treatment Trial II

N. Venkatesh Prajna, Tiruvengada Krishnan, Revathi Rajaraman, Sushila Patel, Ranjeet Shah, Muthiah Srinivasan, Lumbini Devi, Manoranjan Das, Kathryn J. Ray, Kieran S. O'Brien, Catherine E. Oldenburg, Stephen D. McLeod, Michael E. Zegans, Nisha R Acharya, Thomas M. Lietman, Jennifer Rose-Nussbaumer
JAMA Ophthalmol. 2017;135(6):520–525

Adjustable Bilateral Superior Oblique Tendon Advancement for Bilateral Fourth Nerve Palsy

Bata, Bashar M. et al.
American Journal of Ophthalmology, Volume 178, 115 – 121

Association Between Thyroid Disease and UveitisResults From the Pacific Ocular Inflammation Study

Durga S. Borkar, Gelareh Homayounfar, Vivien M. Tham, Kathryn J. Ray, Aleli C. Vinoya, Aileen Uchida, Nisha R. Acharya
JAMA Ophthalmol. 2017;135(6):594–599

Association of Diabetic Macular Edema and Proliferative Diabetic Retinopathy With Cardiovascular DiseaseA Systematic Review and Meta-analysis

Jing Xie, M. Kamran Ikram, Mary Frances Cotch, Barbara Klein, Rohit Varma, Jonathan E. Shaw, Ronald Klein, Paul Mitchell, Ecosse L. Lamoureux, Tien Yin Wong
JAMA Ophthalmol. 2017;135(6):586–593

Association of Structural and Functional Measures With Contrast Sensitivity in Glaucoma

Fatehi, Nima et al.
American Journal of Ophthalmology, Volume 178, 129 – 139

Baseline Factors Associated With 6-Month Visual Acuity and Retinal Thickness Outcomes in Patients With Macular Edema Secondary to Central Retinal Vein Occlusion or Hemiretinal Vein OcclusionSCORE2 Study Report 4

Ingrid U. Scott, Paul C. VanVeldhuisen, Michael S. Ip, Barbara A. Blodi, Neal L. Oden, Jacqueline King, Andrew N. Antoszyk, Mark A. Peters, Michael Tolentino
JAMA Ophthalmol.2017;135(6):639–649

Comparison of MicroRNA Expression in Aqueous Humor of Normal and Primary Open-Angle Glaucoma Patients Using PCR Arrays: A Pilot Study

Hari Jayaram, Jay I. Phillips, Diana C. Lozano, Tiffany E. Choe, William O. Cepurna, Elaine C. Johnson, John C. Morrison, Devin M. Gattey, Julie A. Saugstad, Kate E. Keller
Invest. Ophthalmol. Vis. Sci. 2017;58(7):2884-2890

Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells

Ping Yang, Nikolai P. Skiba, Grace M. Tewkesbury, Victoria M. Treboschi, Peter Baciu, Glenn J. Jaffe
Invest. Ophthalmol. Vis. Sci. 2017;58(7):3073-3085

De novo assembly and annotation of the retinal transcriptome for the Nile grass rat (Arvicanthis ansorgei)

Liu MM, Farkas M, Spinnhirny P, Pevet P, Pierce E, et al.
PLOS ONE 12(7): e0179061

Genotypic and Phenotypic Characteristics of CRB1-Associated Retinal Dystrophies

Talib, Mays et al.
Ophthalmology, Volume 124, Issue 6, 884 – 895

High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy

Thomas Tien, Joyce Zhang, Tetsuya Muto, Dongjoon Kim, Vijay P. Sarthy, Sayon Roy
Invest. Ophthalmol. Vis. Sci. 2017;58(7):2915-2921

Intraoperative Findings in Consecutive Exotropia with and without Adduction Deficit

Hatt, Sarah R. et al.
Ophthalmology, Volume 124, Issue 6, 828 – 834

In Vivo Characteristics of Corneal Endothelium/Descemet Membrane Complex for the Diagnosis of Corneal Graft Rejection

Abou Shousha, Mohamed et al.
American Journal of Ophthalmology, Volume 178, 27 - 37

ISG15 in Host Defense Against Candida albicans Infection in a Mouse Model of Fungal Keratitis

Chen Dong, Nan Gao, Bing X. Ross, Fu-Shin X. Yu
Invest. Ophthalmol. Vis. Sci. 2017;58(7):2948-2958

Marshall M. Parks Memorial Lecture: Ocular Motor Misbehavior in Children

Brodsky, Michael C.
Ophthalmology, Volume 124, Issue 6, 835 – 842

Mutant Fibulin-3 Causes Proteoglycan Accumulation and Impaired Diffusion Across Bruch's Membrane

Astrid Zayas-Santiago, Samuel D. Cross, James B. Stanton, Alan D. Marmorstein, Lihua Y. Marmorstein
Invest. Ophthalmol. Vis. Sci. 2017;58(7):3046-3054

Myopic Shift 5 Years after Intraocular Lens Implantation in the Infant Aphakia Treatment Study

Weakley, David R. et al.
Ophthalmology, Volume 124, Issue 6, 822 – 827

Pattern Recognition Analysis of Age-Related Retinal Ganglion Cell Signatures in the Human Eye

Nayuta Yoshioka, Barbara Zangerl, Lisa Nivison-Smith, Sieu K. Khuu, Bryan W. Jones, Rebecca L. Pfeiffer, Robert E. Marc, Michael Kalloniatis
Invest. Ophthalmol. Vis. Sci. 2017;58(7):3086-3099

Performance of the Spot Vision Screener in Children Younger Than 3 Years of Age

Forcina, Blake D. et al.
American Journal of Ophthalmology, Volume 178, 79 – 83

PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma

Gülçin Gezgin, Sietse J. Luk, Jinfeng Cao, Mehmet Dogrusöz, Dirk M. van der Steen, Renate S. Hagedoorn, Daniëlle Krijgsman, Pieter A. van der Velden, Matthew G. Field, Gregorius P. M. Luyten, Karoly Szuhai, J. William Harbour, Ekaterina S. Jordanova, Mirjam H. M. Heemskerk, Martine J. Jager. JAMA Ophthalmol. 2017;135(6):541–549

Prevalence of Undiagnosed Age-Related Macular Degeneration in Primary Eye Care

David C. Neely, Kevin J. Bray, Carrie E. Huisingh, Mark E. Clark, Gerald McGwin, Cynthia Owsley
JAMA Ophthalmol.2017;135(6):570–575

Pupillary Light Reflexes in Severe Photoreceptor Blindness Isolate the Melanopic Component of Intrinsically Photosensitive Retinal Ganglion Cells

Jason Charng, Samuel G. Jacobson, Elise Heon, Alejandro J. Roman, David B. McGuigan, Rebecca Sheplock, Mychajlo S. Kosyk, Malgorzata Swider, Artur V. Cideciyan
Invest. Ophthalmol. Vis. Sci. 2017;58(7):3215-3224

Specific Alleles of CLN7/MFSD8, a Protein that Localizes to Photoreceptor Synaptic Terminals, Cause a Spectrum of Nonsyndromic Retinal Dystrophy

Kamron N. Khan, Mohammed E. El-Asrag, Cristy A. Ku, Graham E. Holder, Martin McKibbin, Gavin Arno, James A. Poulter, Keren Carss, Tejaswi Bommireddy, Saghar Bagheri, Benjamin Bakall, Hendrik P. Scholl, F. Lucy Raymond, Carmel Toomes, Chris F. Inglehearn, Mark E. Pennesi, Anthony T. Moore, Michel Michaelides, Andrew R. Webster, Manir Ali
Invest. Ophthalmol. Vis. Sci. 2017;58(7):2906-2914

The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

Jessica V. Jasien, Carrie Huisingh, Christopher A. Girkin, J. Crawford Downs
Invest. Ophthalmol. Vis. Sci. 2017;58(7):3225-3230

The Utility of Repeat Culture in Fungal Corneal Ulcer Management: A Secondary Analysis of the MUTT-I Randomized Clinical Trial

Ray, Kathryn J. et al.
American Journal of Ophthalmology, Volume 178, 157 – 162

Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy

Doug D. Chung, Ricardo F. Frausto, Benjamin R. Lin, Evelyn M. Hanser, Zack Cohen, Anthony J. Aldave
Invest. Ophthalmol. Vis. Sci. 2017;58(7):3202-3214

VEGF as a Paracrine Regulator of Conventional Outflow Facility

Ester Reina-Torres, Joanne C. Wen, Katy C. Liu, Guorong Li, Joseph M. Sherwood, Jason Y. H. Chang, Pratap Challa, Cassandra M. Flügel-Koch, W. Daniel Stamer, R. Rand Allingham, Darryl R. Overby Invest. Ophthalmol. Vis. Sci. 2017;58(3):1899-1908

Visual Impairment in Preschool Children in the United StatesDemographic and Geographic Variations From 2015 to 2060

Rohit Varma, Kristina Tarczy-Hornoch, Xuejuan Jiang
JAMA Ophthalmol.2017;135(6):610–616

Visual Sensory and Visual-Cognitive Function and Rate of Crash and Near-Crash Involvement among Older Drivers Using Naturalistic Driving Data

Carrie Huisingh, Emily B. Levitan, Marguerite R. Irvin, Paul MacLennan, Virginia Wadley, Cynthia Owsley Invest. Ophthalmol. Vis. Sci.2017;58(7):2959-2967

β-Zone Parapapillary Atrophy and Rates of Glaucomatous Visual Field ProgressionAfrican Descent and Glaucoma Evaluation Study

C. Gustavo De Moraes, James T. Murphy, Chad M. Kaplan, Jeremy J. Reimann, Alon Skaat, Dana M. Blumberg, Lama Al-Aswad, George A. Cioffi, Christopher A. Girkin, Felipe A. Medeiros, Robert N. Weinreb, Linda Zangwill, Jeffrey M. Liebmann
JAMA Ophthalmol. 2017;135(6):617–623

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May, 2017

Acute Zonal Cone Photoreceptor outer Segment Loss

Aleman TS, Sandhu HS, Serrano LW, Traband A, Lau MK, Adamus G, Avery RA.
JAMA Ophthalmol. 2017;135(5):487-490

A Novel Dominant Mutation in SAG, the Arrestin-1 Gene, Is a Common Cause of Retinitis Pigmentosa in Hispanic Families in the Southwestern United States

Lori S. Sullivan, Sara J. Bowne, Daniel C. Koboldt, Elizabeth L. Cadena, John R. Heckenlively, Kari E. Branham, Dianna H. Wheaton, Kaylie D. Jones, Richard S. Ruiz, Mark E. Pennesi, Paul Yang, David Davis-Boozer, Hope Northrup, Vsevold V. Gurevich, Rui Chen, Mingchu Xu, Yumei Li, David G. Birch, Stephen P. Daiger
Invest. Ophthalmol. Vis. Sci. 2017;58(5):2774-2784

Bim Expression in Endothelial Cells and Pericytes is Essential for Regression of the Fetal Ocular Vasculature

Wang S, Zaitoun IS, Johnson RP, Jamali N, Gurel Z, et al.
PLOS ONE 12(5): e0178198

Biometry Characteristics in Adults and Children with Marfan Syndrome: From the Marfan Eye Consortium of Chicago

Kinori, Michael et al.
American Journal of Ophthalmology, Volume 177, 144 – 149

Defining Outcomes for Clinical Trials of Leber Congenital Amaurosis Caused by GUCY2D Mutations

Jacobson, Samuel G. et al.
American Journal of Ophthalmology, Volume 177, 44 – 57

Factors Affecting Visits to the Emergency Department for Urgent and Nonurgent Ocular Conditions

Stagg, Brian C. et al.
Ophthalmology, Volume 124, Issue 5, 720 – 729

Globe Axial Length Growth at Age 5 Years in the Infant Aphakia Treatment Study

Wilson, M. Edward et al.
Ophthalmology, Volume 124, Issue 5 , 730 – 733

Inferior Rectus Transposition: A Novel Procedure for Abducens Palsy

Velez, Federico G. et al.
American Journal of Ophthalmology, Volume 177, 126 – 130

Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients with Neovascular Age-Related Macular Degeneration.

Joanne C. Wen, Ester Reina-Torres, Joseph M. Sherwood, Pratap Challa, Katy C. Liu, Guorong Li, Jason Y. H. Chang, Scott W. Cousins, Stefanie G. Schuman, Priyatham S. Mettu, W. Daniel Stamer, Darryl R. Overby, R. Rand Allingham
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1893-1898

KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial–Mesenchymal Transition

Anil Tiwari, Chelsea L. Loughner, Sudha Swamynathan, Shivalingappa K. Swamynathan
Invest. Ophthalmol. Vis. Sci. 2017;58(5):2785-2795

Ophthalmic Screening Patterns among Youths with Diabetes Enrolled in a Large US Managed Care Network

Wang SY, Andrews CA, Gardner TW, Wood M, Singer K, Stein JD.
JAMA Ophthalmol. 2017;135(5):432-438

Outcome Measures for Clinical Trials of Leber Congenital Amaurosis Caused by the Intronic Mutation in the CEP290 Gene

Samuel G. Jacobson, Artur V. Cideciyan, Alexander Sumaroka, Alejandro J. Roman, Jason Charng, Monica Lu, Windy Choi, Rebecca Sheplock, Malgorzata Swider, Mychajlo S. Kosyk, Sharon B. Schwartz, Edwin M. Stone, Gerald A. Fishman
Invest. Ophthalmol. Vis. Sci. 2017;58(5):2609-2622

Peripapillary and Macular Vessel Density in Patients with Glaucoma and Single-Hemifield Visual Field Defect

Yarmohammadi, Adeleh et al.
Ophthalmology, Volume 124, Issue 5, 709 – 719

Peripapillary Retinal Nerve Fiber Layer Vascular Microcirculation in Eyes with Glaucoma and Single-Hemifield Visual Field Loss

Chen C, Bojikian KD, Wen JC, Zhang Q, Xin C, Mudumbai RC, Johnstone MA, Chen PP, Wang RK. JAMA Ophthalmol. 2017;135(5):461-468

Peripapillary Retinal Pigment Epithelium Layer Shape Changes from Acetazolamide Treatment in the Idiopathic Intracranial Hypertension Treatment Trial

Jui-Kai Wang, Randy H. Kardon, Johannes Ledolter, Patrick A. Sibony, Mark J. Kupersmith, Mona K. Garvin, for the OCT Sub-Study Committee and the NORDIC Idiopathic Intracranial Hypertension Study Group
Invest. Ophthalmol. Vis. Sci. 2017;58(5):2554-2565

Quantitative Association between Peripapillary Bruch's Membrane Shape and Intracranial Pressure

Amulya Gampa, Gautam Vangipuram, Zainab Shirazi, Heather E. Moss
Invest. Ophthalmol. Vis. Sci. 2017;58(5):2739-2745

Re-evaluating the Incidence of Idiopathic Intracranial Hypertension in an Era of Increasing Obesity

Kilgore, Khin P. et al.
Ophthalmology, Volume 124, Issue 5 , 697 – 700

Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule that Is Necessary for the Intraocular Pressure–Lowering Effects of Latanoprost

Gavin W. Roddy, Kimberly B. Viker, Nelson S. Winkler, Cindy K. Bahler, Bradley H. Holman, David Sheikh-Hamad, Uttio Roy Chowdhury, W. Daniel Stamer, Michael P. Fautsch
Invest. Ophthalmol. Vis. Sci. 2017;58(5):2715-2724

The Growing “Stem Cell Clinic” Problem

Kuriyan, Ajay E. et al.
American Journal of Ophthalmology, Volume 177, xix – xx

Tumor Necrosis Factor Alpha (TNF-α) Disrupts Kir4.1 Channel Expression Resulting in Müller Cell Dysfunction in the Retina

Iraj Hassan, Qianyi Luo, Sreeparna Majumdar, James M. Dominguez, II, Julia V. Busik, Ashay D. Bhatwadekar
Invest. Ophthalmol. Vis. Sci. 2017;58(5):2473-2482

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April, 2017

Accuracy of Optical Coherence Tomography Measurements of Rectus Muscle Insertions in Adult Patients Undergoing Strabismus Surgery

Rossetto, Julia D. et al.
American Journal of Ophthalmology, Volume 176, 236 – 243

Acute Hypoxia Influences Collagen and Matrix Metalloproteinase Expression by Human Keratoconus Cells in vitro

McKay TB, Hjortdal J, Priyadarsini S, Karamichos D.
PLOS ONE 12(4): e0176017

Capturing the Moment of Fusion Loss in Intermittent Exotropia

Economides, John R. et al.
Ophthalmology, Volume 124, Issue 4, 496 – 504

Comparison between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

Andrew R. Miller, Luiz Roisman, Qinqin Zhang, Fang Zheng, Joao Rafael de Oliveira Dias, Zohar Yehoshua, Karen B. Schaal, William Feuer, Giovanni Gregori, Zhongdi Chu, Chieh-Li Chen, Sophie Kubach, Lin An, Paul F. Stetson, Mary K. Durbin, Ruikang K. Wang, Philip J. Rosenfeld
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1499-1505

Comprehensive Characterization of DNA Methylation Changes in Fuchs Endothelial Corneal Dystrophy

Khuc E, Bainer R, Wolf M, Clay SM, Weisenberger DJ, et al.
PLOS ONE 12(4): e0175112

Efficacy and Toxicity of Intravitreous Chemotherapy for Retinoblastoma: Four-Year Experience

Francis, Jasmine H. et al.
Ophthalmology, Volume 124, Issue 4, 488 – 495

Evaluation of Optical Coherence Tomography to Detect Elevated Intracranial Pressure in Children

Swanson JW, Aleman TS, Xu W, Ying G, Pan W, Liu GT, Lang S, Heuer GG, Storm PB, Bartlett SP, Katowitz WR, Taylor JA.
JAMA Ophthalmol. 2017;135(4):320-328

Exome Sequence Analysis of 14 Families with High Myopia

Bethany A. Kloss, Stuart W. Tompson, Kristina N. Whisenhunt, Krystina L. Quow, Samuel J. Huang, Derek M. Pavelec, Thomas Rosenberg, Terri L. Young
Invest. Ophthalmol. Vis. Sci. 2017;58(4):1982-1990

Five-Year Pooled Data Analysis of the Ahmed Baerveldt Comparison Study and the Ahmed Versus Baerveldt Study

Christakis, Panos G. et al.
American Journal of Ophthalmology, Volume 176, 118 – 126

High-Resolution Imaging of Intraretinal Structures in Active and Resolved Central Serous Chorioretinopathy

Ryan N. Vogel, Christopher S. Langlo, Drew Scoles, Joseph Carroll, David V. Weinberg, Judy E. Kim Invest. Ophthalmol. Vis. Sci. 2017;58(1):42-49

Incidence of and Risk Factors for Developing Idiopathic Macular Hole among a Diverse Group of Patients throughout the United States

Ali FS, Stein JD, Blachley TS, Ackley S, Stewart JM.
JAMA Ophthalmol. 2017;135(4):299-305

Intravitreal Bevacizumab for the Treatment of Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy

Parikh, Rupin N. et al.
American Journal of Ophthalmology, Volume 176, 194 – 202

Multimodal Fundus Imaging of Sodium Iodate-Treated Mice Informs RPE Susceptibility and Origins of Increased Fundus Autofluorescence

Jin Zhao, Hye Jin Kim, Janet R. Sparrow
Invest. Ophthalmol. Vis. Sci. 2017;58(4):2152-2159

Plus Disease in Retinopathy of Prematurity: Diagnostic Trends in 2016 Versus 2007

Moleta, ChaceChiang, Michael F. et al.
American Journal of Ophthalmology, Volume 176, 70 – 76

Prevalence of Antiretinal Antibodies in Acute Zonal Occult Outer Retinopathy: A Comprehensive Review of 25 Cases

Qian, Cynthia X. et al.
American Journal of Ophthalmology, Volume 176, 210 – 218

Prominin-1 Is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium

Sujoy Bhattacharya, Jinggang Yin, Christina S. Winborn, Qiuhua Zhang, Junming Yue, Edward Chaum
Invest. Ophthalmol. Vis. Sci. 2017;58(4):2366-2387

Quality of Life in the Tube Versus Trabeculectomy Study

Kotecha, Aachal et al.
American Journal of Ophthalmology, Volume 176, 228 – 235

Quantitative Microvascular Analysis of Retinal Venous Occlusions by Spectral Domain Optical Coherence Tomography Angiography

Koulisis N, Kim AY, Chu Z, Shahidzadeh A, Burkemper B, et al.
PLOS ONE 12(4): e0176404

Reflectance Spectrum and Birefringence of the Retinal Nerve Fiber Layer with Hypertensive Damage of Axonal Cytoskeleton

Xiang-Run Huang, Robert W. Knighton, Ye Z. Spector, Jianzhong Qiao, Wei Kong, Qi Zhao
Invest. Ophthalmol. Vis. Sci. 2017;58(4):2118-2129

Self-reported use of Eye Care Among Adult Chinese Americans: The Chinese American Eye Study

Jiang, Xuejuan et al.
American Journal of Ophthalmology, Volume 176, 183 – 193

The Effect of Treatment of Idiopathic Intracranial Hypertension on Prevalence of Retinal and Choroidal Folds

Kupersmith, Mark J. et al.
American Journal of Ophthalmology, Volume 176, 77 – 86

The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy

Anna C. S. Tan, Polina Astroz, Kunal K. Dansingani, Jason S. Slakter, Lawrence A. Yannuzzi, Christine A. Curcio, K. Bailey Freund
Invest. Ophthalmol. Vis. Sci. 2017;58(4):2349-2358

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March, 2017

Agreement of Ocular Symptom Reporting between Patient-Reported Outcomes and Medical Records 

Valikodath NG, Newman-Casey PA, Lee PP, Musch DC, Niziol LM, Woodward MA.
JAMA Ophthalmol. 2017;135(3):225-231

A Novel Flexible Microfluidic Meshwork to Reduce Fibrosis in Glaucoma Surgery

Amoozgar B, Wei X, Hui Lee J, Bloomer M, Zhao Z, et al.
PLOS ONE 12(3): e0172556

Arap1 Deficiency Causes Photoreceptor Degeneration in Mice

Ala Moshiri, Devin Humpal, Brian C. Leonard, Denise M. Imai, Addy Tham, Lynette Bower, Dave Clary, Thomas M. Glaser, K. C. Kent Lloyd, Christopher J. Murphy
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1709-1718

Automated Quantitation of Choroidal Neovascularization: A Comparison Study between Spectral-Domain and Swept-Source OCT Angiograms

Qinqin Zhang, Chieh-Li Chen, Zhongdi Chu, Fang Zheng, Andrew Miller, Luiz Roisman, Joao Rafael de Oliveira Dias, Zohar Yehoshua, Karen B. Schaal, William Feuer, Giovanni Gregori, Sophie Kubach, Lin An, Paul F. Stetson, Mary K. Durbin, Philip J. Rosenfeld, Ruikang K. Wang
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1506-1513

Corneal Stromal Stem Cells Reduce Corneal Scarring by Mediating Neutrophil Infiltration After Wounding

Hertsenberg AJ, Shojaati G, Funderburgh ML, Mann MM, Du Y, et al.
PLOS ONE 12(3): e0171712

Deletion of Efemp1 Is Protective Against the Development of Sub-RPE Deposits in Mouse Eyes

James B. Stanton, Alan D. Marmorstein, Youwen Zhang, Lihua Y. Marmorstein
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1455-1461

Differences in Clinical Activity and Medicare Payments for Female vs Male Ophthalmologists

Reddy AK, Bounds GW, Bakri SJ, Gordon LK, Smith JR, Haller JA, Berrocal AM, Thorne JE.
JAMA Ophthalmol. 2017;135(3):205-213

Editing Is Fun but Change Is Good

Bartley, George B.
Ophthalmology, Volume 124, Issue 3, 276 – 277

Gene Augmentation Therapy for a Missense Substitution in the cGMP-Binding Domain of Ovine CNGA3 Gene Restores Vision in Day-Blind Sheep

Elisha Gootwine, Mazen Abu-Siam, Alexey Obolensky, Alex Rosov, Hen Honig, Tali Nitzan, Andrey Shirak, Raaya Ezra-Elia, Esther Yamin, Eyal Banin, Edward Averbukh, William W. Hauswirth, Ron Ofri, Eyal Seroussi
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1577-1584

High-Speed Adaptive Optics Line Scan Confocal Retinal Imaging for Human Eye

Lu J, Gu B, Wang X, Zhang Y.
PLOS ONE 12(3): e0169358

Intraocular Delivery of miR-146 Inhibits Diabetes-Induced Retinal Functional Defects in Diabetic Rat Model

Pei Zhuang, Chithra K. Muraleedharan, Shunbin Xu
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1646-1655

In Vivo Bioluminescence Imaging for Longitudinal Monitoring of Inflammation in Animal Models of Uveitis

Michal B. Gutowski, Leslie Wilson, Russell N. Van Gelder, Kathryn L. Pepple
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1521-1528

Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats using Spectral-Domain Optical Coherence Tomography

Renee C. Ryals, Michael D. Andrews, Shreya Datta, Aaron S. Coyner, Cody M. Fischer, Yuquan Wen, Mark E. Pennesi, Trevor J. McGill
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1378-1386

Mechanism of Action of Selective Laser Trabeculoplasty and Predictors of Response

Vikas Gulati, Shan Fan, Bret J. Gardner, Shane J. Havens, Marie T. Schaaf, Donna G. Neely, Carol B. Toris
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1462-1468

Multimodal MR-Imaging Reveals Large-Scale Structural and Functional Connectivity Changes in Profound Early Blindness

Bauer CM, Hirsch GV, Zajac L, Koo BB, Collignon O, et al.
PLOS ONE 12(3): e0173064

Natural History of the Central Structural Abnormalities in Choroideremia

Aleman, Tomas S. et al.
Ophthalmology, Volume 124, Issue 3, 359 – 373

Nonarteritic Anterior Ischemic Optic Neuropathy and Intraocular Surgery

McCulley, Timothy J. et al.
American Journal of Ophthalmology, Volume 175, xiv – xvi

Prevalence and Risk Factors for Refractive Error in Adult Chinese Americans: The Chinese American Eye Study

Varma, RohitVarma, Rohit et al.
American Journal of Ophthalmology, Volume 175, 201 – 212

Protective Effect of Met12, a Small Peptide Inhibitor of Fas, on the Retinal Pigment Epithelium and Photoreceptor after Sodium Iodate Injury

Jianhui Xiao, Jingyu Yao, Lin Jia, Chengmao Lin, David N. Zacks 
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1801-1810

Quantifying Fundus Autofluorescence in Patients with Retinitis Pigmentosa

Kaspar Schuerch, Russell L. Woods, Winston Lee, Tobias Duncker, François C. Delori, Rando Allikmets, Stephen H. Tsang, Janet R. Sparrow
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1843-1855

Silk-Derived Protein Enhances Corneal Epithelial Migration, Adhesion, and Proliferation

Waleed Abdel-Naby, Brigette Cole, Aihong Liu, Jingbo Liu, Pengxia Wan, Victor H. Guaiquil, Ryan Schreiner, David Infanger, Brian D. Lawrence, Mark I. Rosenblatt
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1425-1433

Subretinal Glial Membranes in Eyes with Geographic Atrophy

Malia M. Edwards, D. Scott McLeod, Imran A. Bhutto, Rhonda Grebe, Maeve Duffy, Gerard A. Lutty
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1352-1367

Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration

Perciliz L. Tan, Melanie E. Garrett, Jason R. Willer, Peter A. Campochiaro, Betsy Campochiaro, Donald J. Zack, Allison E. Ashley-Koch, Nicholas Katsanis
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1570-1576

Tangent Screen Perimetry in the Evaluation of Visual Field Defects Associated with Ptosis and Dermatochalasis

Fuller ML, Briceño CA, Nelson CC, Bradley EA
PLOS ONE 12(3): e0174607

Thick Prelaminar Tissue Decreases Lamina Cribrosa Visibility

Katie A. Lucy, Bo Wang, Joel S. Schuman, Richard A. Bilonick, Yun Ling, Larry Kagemann, Ian A. Sigal, Ireneusz Grulkowski, Jonathan J. Liu, James G. Fujimoto, Hiroshi Ishikawa, Gadi Wollstein
Invest. Ophthalmol. Vis. Sci. 2017;58(3):1751-1757

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February, 2017

Assessment of feedback modalities for wearable visual aids in blind mobility

Adebiyi A, Sorrentino P, Bohlool S, Zhang C, Arditti M, et al.
PLOS ONE 12(2): e0170531

Association of Pediatric Choroidal Neovascular Membranes at the Temporal Edge of Optic Nerve and Retinochoroidal Coloboma

Grewal, Dilraj Singh et al.
American Journal of Ophthalmology , Volume 174 , 104 - 112

Astrocytes in the Optic Nerve Head of Glaucomatous Mice Display a Characteristic Reactive Phenotype

Rui Wang, Philip Seifert, Tatjana C. Jakobs
Invest. Ophthalmol. Vis. Sci. 2017;58(2):924-932

Clinical Characterization of CNGB1-Related Autosomal Recessive Retinitis Pigmentosa

Hull S, Attanasio M, Arno G, Carss K, Robson AG, Thompson DA, Plagnol V, Michaelides M, Holder GE, Henderson RH, Raymond FL, Moore AT, Webster AR.
JAMA Ophthalmol. 2017;135(2):137-144

Comparison of Bruch's Membrane Opening Minimum Rim Width Among Those With Normal Ocular Health by Race

Rhodes, Lindsay A. et al.
American Journal of Ophthalmology , Volume 174 , 113 – 118

Connective tissue growth factor is not necessary for haze formation in excimer laser wounded mouse corneas

Feng X, Pi L, Sriram S, Schultz GS, Gibson DJ
PLOS ONE 12(2): e0172304

Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid–Independent Pathway

Antionette L. Williams, Jessica Eason, Bahaar Chawla, Brenda L. Bohnsack
Invest. Ophthalmol. Vis. Sci. 2017;58(2):1084-1097

Dacryocystorhinostomy for Acquired Nasolacrimal Duct Stenosis in the Elderly (≥80 Years of Age)

Tooley, Andrea A. et al.
Ophthalmology, Volume 124, Issue 2, 263 – 267

Deformation of Optic Nerve Head and Peripapillary Tissues by Horizontal Duction

Chang, Melinda Y. et al.
American Journal of Ophthalmology , Volume 174 , 85 - 94

Diplopia in Medically and Surgically Treated Patients with Glaucoma

Sun, Philip Y. et al.
Ophthalmology, Volume 124, Issue 2, 257 – 262

Endophthalmitis After Clear Corneal Cataract Surgery: Outcomes Over Two Decades

Yannuzzi, Nicolas A. et al.
American Journal of Ophthalmology , Volume 174 , 155 - 159

En Face Optical Coherence Tomography Imaging for the Detection of Nascent Geographic Atrophy

Schaal, Karen B. et al.
American Journal of Ophthalmology , Volume 174 , 145 - 154

Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina

Ko Uoon Park, Grace Randazzo, Kenneth L. Jones, Joseph A. Brzezinski, IV
Invest. Ophthalmol. Vis. Sci. 2017;58(2):1137-1150

Increased Retinal Oxygen Metabolism Precedes Microvascular Alterations in Type 1 Diabetic Mice

Wenzhong Liu, Shoujian Wang, Brian Soetikno, Ji Yi, Kevin Zhang, Siyu Chen, Robert A. Linsenmeier, Christine M. Sorenson, Nader Sheibani, Hao F. Zhang
Invest. Ophthalmol. Vis. Sci. 2017;58(2):981-989

Longitudinal Examination of Frequency of and Risk Factors for Severe Dry Eye Symptoms in US Veterans

Ong ES, Alghamdi YA, Levitt RC, McClellan AL, Lewis G, Sarantopoulos CD, Felix ER, Galor A.
JAMA Ophthalmol. 2017;135(2):116-123

Measuring Trachomatous Inflammation-Intense (TI) when Prevalence is Low Provides Data on Infection with Chlamydia trachomatis

Andrea I. Zambrano, Beatriz E. Muñoz, Harran Mkocha, Laura Dize, Charlotte A. Gaydos, Thomas Quinn, Sheila K. West
Invest. Ophthalmol. Vis. Sci. 2017;58(2):997-1000

Ophthalmic Manifestations and Causes of Vision Impairment in Ebola Virus Disease Survivors in Monrovia, Liberia

Shantha, Jessica G. et al.
Ophthalmology, Volume 124, Issue 2, 170 – 177

Optical Coherence Tomography Angiography Characteristics of Iris Melanocytic Tumors

Skalet, Alison H. et al.
Ophthalmology, Volume 124, Issue 2, 197 – 204

Perioperative Retinal Artery Occlusion

Calway, Tyler et al.
Ophthalmology, Volume 124, Issue 2, 189 – 196

Postretinal Structure and Function in Severe Congenital Photoreceptor Blindness Caused by Mutations in the GUCY2D Gene

Geoffrey K. Aguirre, Omar H. Butt, Ritobrato Datta, Alejandro J. Roman, Alexander Sumaroka, Sharon B. Schwartz, Artur V. Cideciyan, Samuel G. Jacobson
Invest. Ophthalmol. Vis. Sci. 2017;58(2):959-973

Retinal Microvascular Network and Microcirculation Assessments in High Myopia

Li, Min et al.
American Journal of Ophthalmology , Volume 174 , 56 – 67

Retinopathy of prematurity: A comprehensive risk analysis for prevention and prediction of disease

Owen LA, Morrison MA, Hoffman RO, Yoder BA, DeAngelis MM
PLOS ONE 12(2): e017146

Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model

Matthew G. Pilgrim, Imre Lengyel, Antonio Lanzirotti, Matt Newville, Sarah Fearn, Eszter Emri, Jonathan C. Knowles, Jeffrey D. Messinger, Russell W. Read, Clyde Guidry, Christine A. Curcio
Invest. Ophthalmol. Vis. Sci. 2017;58(2):708-719

The relation between exercise and glaucoma in a South Korean population-based sample

Lin SC, Wang SY, Pasquale LR, Singh K, Lin SC
PLOS ONE 12(2): e0171441

Thirteen-Year Follow-up of Optic Disc Hemorrhages in the Ocular Hypertension Treatment Study

Budenz, Donald L. et al.
American Journal of Ophthalmology , Volume 174 , 126 - 133

Use of a Supplemental Oxygen Protocol to Suppress Progression of Retinopathy of Prematurity

Tarah T. Colaizy, Susannah Longmuir, Kevin Gertsch, Michael David Abràmoff, Jonathan M. Klein
Invest. Ophthalmol. Vis. Sci. 2017;58(2):887-891

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January, 2017

Comparison of Aqueous Outflow Facility Measurement by Pneumatonography and Digital Schiøtz Tonography

Arash Kazemi, Jay W. McLaren, Shuai-Chun Lin, Carol B. Toris, Vikas Gulati, Sayoko E. Moroi, Arthur J. Sit
Invest. Ophthalmol. Vis. Sci. 2017;58(1):204-210

Compound 49b Regulates ZO-1 and Occludin Levels in Human Retinal Endothelial Cells and in Mouse Retinal Vasculature

Youde Jiang, Li Liu, Jena J. Steinle
Invest. Ophthalmol. Vis. Sci. 2017;58(1):185-189

Confirmation of the OVOL2 Promoter Mutation c.-307T>C in Posterior Polymorphous Corneal Dystrophy 1

Chung DD, Frausto RF, Cervantes AE, Gee KM, Zakharevich M, et al.
PLOS ONE 12(1): e0169215

Effect of Corneal Nerve Ablation on Immune Tolerance Induced by Corneal Allografts, Oral Immunization, or Anterior Chamber Injection of Antigens

Juan Mo, Sudha Neelam, Jessamee Mellon, Joseph R. Brown, Jerry Y. Niederkorn
Invest. Ophthalmol. Vis. Sci. 2017;58(1):137-148

Estimating the Osmolarities of Tears During Evaporation through the “Eyes” of the Corneal Nerves

Harumitsu Hirata, Kamila Mizerska, Valentina Dallacasagrande, Mark I. Rosenblatt
Invest. Ophthalmol. Vis. Sci. 2017;58(1):168-178

Evaluation of Therapeutic Tissue Crosslinking (TXL) for Myopia using Second Harmonic Generation Signal Microscopy in Rabbit Sclera

Mariya Zyablitskaya, Anna Takaoka, Emilia L. Munteanu, Takayuki Nagasaki, Stephen L. Trokel, David C. Paik
Invest. Ophthalmol. Vis. Sci. 2017;58(1):21-29

Exposure Stress Induces Reversible Corneal Graft Opacity in Recipients with Herpes Simplex Virus-1 Infections

Alexander M. Rowe, Hongmin Yun, Robert L. Hendricks
Invest. Ophthalmol. Vis. Sci. 2017;58(1):35-41

Formation and Clearance of All-Trans-Retinol in Rods Investigated in the Living Primate Eye with Two-Photon Ophthalmoscopy

Robin Sharma, Christina Schwarz, Jennifer J. Hunter, Grazyna Palczewska, Krzysztof Palczewski, David R. Williams
Invest. Ophthalmol. Vis. Sci. 2017;58(1):604-613

Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

Wei-Sheng Chen*, Zhiyi Cao, Hakon Leffler, Ulf J. Nilsson, Noorjahan Panjwani
Invest. Ophthalmol. Vis. Sci. 2017;58(1):9-20

High-Resolution Imaging of Intraretinal Structures in Active and Resolved Central Serous Chorioretinopathy

Ryan N. Vogel, Christopher S. Langlo, Drew Scoles, Joseph Carroll, David V. Weinberg, Judy E. Kim; Invest. Ophthalmol. Vis. Sci. 2017;58(1):42-49

Incidence and Etiologies of Acquired Third Nerve Palsy using a Population-Based Method

Fang C, Leavitt JA, Hodge DO, Holmes JM, Mohney BG, Chen JJ.
JAMA Ophthalmol. 2017;135(1):23-28

Proteomic Analysis of the Bovine and Human Ciliary Zonule

Alicia De Maria, Phillip A. Wilmarth, Larry L. David, Steven Bassnett
Invest. Ophthalmol. Vis. Sci. 2017;58(1):573-585

Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation in a Murine Model of Sjögren's Syndrome

Mihir Shah, Maria C. Edman, Srikanth Reddy Janga, Frances Yarber, Zhen Meng, Wannita Klinngam, Jonathan Bushman, Tao Ma, Siyu Liu, Stan Louie, Arjun Mehta, Chuanqing Ding, J. Andrew MacKay, Sarah F. Hamm-Alvarez
Invest. Ophthalmol. Vis. Sci. 2017;58(1):372-385

Recent-Onset Bilateral Blurred Vision

Soin K, Feinstein EG, Guo J.
JAMA Ophthalmol. 2017;135(1):71-72

Safety of Concurrent Boston Type I Keratoprosthesis and Glaucoma Drainage Device Implantation

Lenis, Tamara L. et al.
Ophthalmology, Volume 124, Issue 1, 12 – 19

The Ciliopathy Gene ahi1 is Required for Zebrafish Cone Photoreceptor Outer Segment Morphogenesis and Survival

Emma M. Lessieur, Joseph Fogerty, Robert J. Gaivin, Ping Song, Brian D. Perkins 
Invest. Ophthalmol. Vis. Sci. 2017;58(1):448-460

The Pattern of Retinal Ganglion Cell Loss in OPA1-Related Autosomal Dominant Optic Atrophy Inferred from Temporal, Spatial, and Chromatic Sensitivity Losses

Anna Majander, Catarina João, Andrew T. Rider, G. Bruce Henning, Marcela Votruba, Anthony T. Moore, Patrick Yu-Wai-Man, Andrew Stockman
Invest. Ophthalmol. Vis. Sci. 2017;58(1):502-516

Trinucleotide Repeat Expansion in the Transcription Factor 4 (TCF4) Gene Leads to Widespread mRNA Splicing Changes in Fuchs' Endothelial Corneal Dystrophy

Eric D. Wieben, Ross A. Aleff, Xiaojia Tang, Malinda L. Butz, Krishna R. Kalari, Edward W. Highsmith, Jin Jen, George Vasmatzis, Sanjay V. Patel, Leo J. Maguire, Keith H. Baratz, Michael P. Fautsch
Invest. Ophthalmol. Vis. Sci. 2017;58(1):343-352

Vision Loss in a Teenage Girl With Postconcussion Syndrome

Al-khersan H, Hain T, Grassi MA.
JAMA Ophthalmol. 2017;135(1):75-76

Visual Outcomes after Vitrectomy for Terson Syndrome Secondary to Traumatic Brain Injury

Narayanan, Raja et al.
Ophthalmology , Volume 124 , Issue 1 , 118 - 122

β2–Adrenergic Receptor Antagonism Attenuates CNV through Inhibition of VEGF and IL-6 Expression

Jeremy A. Lavine, Mitra Farnoodian, Shoujian Wang, Soesiawati R. Darjatmoko, Lynda S. Wright, David M. Gamm, Michael S. Ip, Christine M. Sorenson, Nader Sheibani
Invest. Ophthalmol. Vis. Sci. 2017;58(1):299-308


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