Research to Prevent Blindness

2016 New Research - October

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Analysis of Cerebrospinal Fluid Pressure Estimation using Formulae Derived from Clinical Data

David Fleischman, Amanda K. Bicket, Sandra S. Stinnett, John P. Berdahl, Jost B. Jonas, Ning Li Wang, Michael P. Fautsch, R. Rand Allingham
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5625-5630

Associations Between Retinal Pigment Epithelium and Drusen Volume Changes During the Lifecycle of Large Drusenoid Pigment Epithelial Detachments

Chandrakumar Balaratnasingam, Lawrence A. Yannuzzi, Christine A. Curcio, William H. Morgan, Giuseppe Querques, Vittorio Capuano, Eric Souied, Jesse Jung, K. Bailey Freund
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5479-5489

Automated Quantification of Nonperfusion in Three Retinal Plexuses using Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy

Miao Zhang, Thomas S. Hwang, Changlei Dongye, David J. Wilson, David Huang, Yali Jia
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5101-5106

Characterization of Chorioretinopathy Associated with Mitochondrial Trifunctional Protein Disorders

Boese, Erin A. et al.
Ophthalmology, Volume 123, Issue 10, 2183 – 2195

Chorioretinal Lesions in a Case of Melanoma-Associated Retinopathy Treated with Pembrolizumab

Roberts P, Fishman GA, Joshi K, Jampol LM.
JAMA Ophthalmol. 2016;134(10):1184-1188

Circadian and Dopaminergic Regulation of Fatty Acid Oxidation Pathway Genes in Retina and Photoreceptor Cells

Vancura P, Wolloscheck T, Baba K, Tosini G, Iuvone PM, et al.
PLOS ONE 11(10): e0164665

Comparison of Outcomes of Laser Trabeculoplasty Performed by Optometrists vs. Ophthalmologists in Oklahoma

Stein JD, Zhao PY, Andrews C, Skuta GL.
JAMA Ophthalmol. 2016;134(10):1095-1101

Details of the Collagen and Elastin Architecture in the Human Limbal Conjunctiva, Tenon's Capsule and Sclera Revealed by Two-Photon Excited Fluorescence Microscopy

Choul Yong Park, Catherine M. Marando, Jason A. Liao, Jimmy K. Lee, Jiwon Kwon, Roy S. Chuck; Invest. Ophthalmol. Vis. Sci. 2016;57(13):5602-5610

Diagnostic Utility of Ocular Symptoms and Vision for Cytomegalovirus Retinitis

Liu Y, Chen AS, Kamphaengkham S, Leenasirimakul P, Jirawison C, et al.
PLOS ONE 11(10): e0165564

Evaluation of Postoperative Povidone-Iodine in Adjustable Suture Strabismus Surgery to Reduce Suture Colonization: A Randomized Clinical Trial

Rossetto JD, Suwannaraj S, Cavuoto KM, Spierer O, Miller D, McKeown CA, Capo H. 
JAMA Ophthalmol. 2016;134(10):1151-1155

Extraocular Muscle Compartments in Superior Oblique Palsy

Soh Youn Suh, Robert A. Clark, Alan Le, Joseph L. Demer
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5535-5540

Fundus Camera-Delivered Light-Induced Retinal Degeneration in Mice with the RPE65 Leu450Met Variant is Associated with Oxidative Stress and Apoptosis

Xin Zhong, Bogale Aredo, Yi Ding, Kaiyan Zhang, Cynthia X. Zhao, Rafael L. Ufret-Vincenty
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5558-5567

Gene Therapy and Stem Cell Transplantation in Retinal Disease: The New Frontier

MacLaren, Robert E. et al.
Ophthalmology, Volume 123, Issue 10, S98 - S106

Glycyrrhizin Reduces HMGB1 and Bacterial Load in Pseudomonas aeruginosa Keratitis

Sandamali A. Ekanayaka, Sharon A. McClellan, Ronald P. Barrett, Shikhil Kharotia, Linda D. Hazlett
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5799-5809

Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione

Matsunaga D, Sreekumar PG, Ishikawa K, Terasaki H, Barron E, et al.
PLOS ONE 11(10): e0165150

Improved Automated Detection of Diabetic Retinopathy on a Publicly Available Dataset through Integration of Deep Learning

Michael David Abràmoff, Yiyue Lou, Ali Erginay, Warren Clarida, Ryan Amelon, James C. Folk, Meindert Niemeijer
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5200-5206

Latanoprost-Eluting Contact Lenses in Glaucomatous Monkeys

Ciolino, Joseph B. et al.
Ophthalmology, Volume 123, Issue 10, 2085 – 2092

Lid Wiper Microvascular Responses as an Indicator of Contact Lens Discomfort

Deng, Zhihong et al.
American Journal of Ophthalmology, Volume 170, 197 – 205

Long-term Follow-up of Patients with Retinitis Pigmentosa Receiving Intraocular Ciliary Neurotrophic Factor Implants

Birch, David G. et al.
American Journal of Ophthalmology, Volume 170, 10 – 14

Loss of Axin2 Causes Ocular Defects During Mouse Eye Development

Ashley Alldredge, Sabine Fuhrmann
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5253-5262

Melanopsin Phototransduction Contributes to Light-Evoked Choroidal Expansion and Rod L-Type Calcium Channel Function In Vivo

Bruce A. Berkowitz, Tiffany Schmidt, Robert H. Podolsky, Robin Roberts
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5314-5319

Optical Coherence Tomography Angiography Analysis of Perfused Peripapillary Capillaries in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma

Nicole K. Scripsema, Patricia M. Garcia, Richard D. Bavier, Toco Y. P. Chui, Brian D. Krawitz, Shelley Mo, Steven A. Agemy, Luna Xu, Yijie B. Lin, Joseph F. Panarelli, Paul A. Sidoti, James C. Tsai, Richard B. Rosen
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT611-OCT620

Oxygen Saturation of Retinal Vessels in All Stages of Diabetic Retinopathy and Correlation to Ultra-Wide Field Fluorescein Angiography

Abhilash Guduru, Teresa G. Martz, Alexa Waters, Abhijit V. Kshirsagar, Seema Garg
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5278-5284

p16 Expression Is Not a Surrogate Marker for High-Risk Human Papillomavirus Infection in Periocular Sebaceous Carcinoma

Stagner, Anna M. et al.
American Journal of Ophthalmology, Volume 170, 168 – 175

Patterns of Laboratory Testing Utilization Among Uveitis Specialists

Lee, Cecilia S. et al.
American Journal of Ophthalmology, Volume 170, 161 – 167

Paucibacterial Microbiome and Resident DNA Virome of the Healthy Conjunctiva

Thuy Doan, Lakshmi Akileswaran, Dallin Andersen, Benjamin Johnson, Narae Ko, Angira Shrestha, Valery Shestopalov, Cecilia S. Lee, Aaron Y. Lee, Russell N. Van Gelder
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5116-5126

Public Attitudes About Eye and Vision Health

Scott AW, Bressler NM, Ffolkes S, Wittenborn JS, Jorkasky J.
JAMA Ophthalmol. 2016;134(10):1111-1118

Retinal Diseases Caused by Mutations in Genes Not Specifically Associated with the Clinical Diagnosis

Wang X, Feng Y, Li J, Zhang W, Wang J, et al.
PLOS ONE 11(10): e0165405

Same-site Trabeculectomy Revision for Failed Trabeculectomy: Outcomes and Risk Factors for Failure

Hirunpatravong, Pradtana et al.
American Journal of Ophthalmology, Volume 170, 110 – 118

The Ahmed Versus Baerveldt Study

Christakis, Panos G. et al.
Ophthalmology, Volume 123, Issue 10, 2093 – 2102

The Bionic Eye

Humayun, Mark S. et al.
Ophthalmology, Volume 123, Issue 10, S89 - S97

The Effects of Diabetic Retinopathy Stage and Light Flicker on Inner Retinal Oxygen Extraction Fraction

Anthony E. Felder, Justin Wanek, Norman P. Blair, Charlotte E. Joslin, Katherine C. Brewer, Felix Y. Chau, Jennifer I. Lim, Yannek I. Leiderman, Mahnaz Shahidi
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5586-5592

The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated with the Continued Progression of Diabetic Retinopathy

Manish Mishra, Renu A. Kowluru
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5748-5757

The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions

Jacey H. Ma, Joshua J. Wang, Junhua Li, Bruce A. Pfeffer, Yiming Zhong, Sarah X. Zhang
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5244-5252

Thy-1 Regulates VEGF-Mediated Choroidal Endothelial Cell Activation and Migration: Implications in Neovascular Age-Related Macular Degeneration

Haibo Wang, Xiaokun Han, Eric Kunz, M. Elizabeth Hartnett
Invest. Ophthalmol. Vis. Sci. 2016;57(13):5525-5534


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