Research to Prevent Blindness

2016 New Research - July

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African Descent and Glaucoma Evaluation Study (ADAGES)

Skaat, Alon et al.
Ophthalmology, Volume 123, Issue 7, 1476 – 1483

Alterations in Retinal Layer Thickness and Reflectance at Different Stages of Diabetic Retinopathy by En Face Optical Coherence Tomography

Justin Wanek, Norman P. Blair, Felix Y. Chau, Jennifer I. Lim, Yannek I. Leiderman, Mahnaz Shahidi Invest. Ophthalmol. Vis. Sci.2016;57(9):OCT341-OCT347

Aqueous Flow Measured by Fluorophotometry in the Mouse

Carol B. Toris, Shan Fan, Thomas V. Johnson, Lucinda J. Camras, Cassandra L. Hays, Hong Liu, Bruce M. Ishimoto
Invest. Ophthalmol. Vis. Sci. 2016;57(8):3844-3852

A Review of Adaptive Optics Optical Coherence Tomography: Technical Advances, Scientific Applications, and the Future

Ravi S. Jonnal, Omer P. Kocaoglu, Robert J. Zawadzki, Zhuolin Liu, Donald T. Miller, John S. Werner
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT51-OCT68

Autophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients

Want A, Gillespie SR, Wang Z, Gordon R, Iomini C, et al.
PLoS ONE 11(7): e0157404

Changes in Course of Retinopathy of Prematurity from 1986 to 2013

Quinn, Graham E. et al.
Ophthalmology, Volume 123, Issue 7, 1595 – 1600

Comparison of Newer IOL Power Calculation Methods for Eyes with Previous Radial Keratotomy

Jack X. Ma, Maolong Tang, Li Wang, Mitchell P. Weikert, David Huang, Douglas D. Koch 
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT162-OCT168

Cone Photoreceptor Structure in Patients with X-Linked Cone Dysfunction and Red-Green Color Vision Deficiency

Emily J. Patterson, Melissa Wilk, Christopher S. Langlo, Melissa Kasilian, Michael Ring, Robert B. Hufnagel, Adam M. Dubis, James J. Tee, Angelos Kalitzeos, Jessica C. Gardner, Zubair M. Ahmed, Robert A. Sisk, Michael Larsen, Stacy Sjoberg, Thomas B. Connor, Alfredo Dubra, Jay Neitz, Alison J. Hardcastle, Maureen Neitz, Michel Michaelides, Joseph Carroll
Invest. Ophthalmol. Vis. Sci. 2016;57(8):3853-3863

Cortical Representation of a Myopic Peripapillary Crescent

Adams, Daniel L. et al.
Ophthalmology, Volume 123, Issue 7, 1494 – 1499

CrxRdy Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis

Laurence M. Occelli, Nicholas M. Tran, Kristina Narfström, Shiming Chen, Simon M. Petersen-Jones Invest. Ophthalmol. Vis. Sci. 2016;57(8):3780-3792

Descemet Stripping Endothelial Keratoplasty

Price, Marianne O. et al.
Ophthalmology, Volume 123, Issue 7, 1421 – 1427

Driver Mutations in Uveal Melanoma Associations with Gene Expression Profile and Patient Outcomes

Decatur CL, Ong E, Garg N, Anbunathan H, Bowcock AM, Field MG, Harbour JW.
JAMA Ophthalmol.2016;134(7):728-733

Epidemiology of Herpes Zoster Ophthalmicus

Tran, Kimberly D. et al.
Ophthalmology, Volume 123, Issue 7, 1469 – 1475

Evaluating Polypoidal Choroidal Vasculopathy with Optical Coherence Tomography Angiography

Min Wang, Yao Zhou, Simon S. Gao, Wei Liu, Yongheng Huang, David Huang, Yali Jia
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT526-OCT532

Glaucoma and Driving: On-Road Driving Characteristics

Wood JM, Black AA, Mallon K, Thomas R, Owsley C.
PLoS ONE 11(7): e0158318

Glaucoma Increases Retinal Surface Contour Variability as Measured by Optical Coherence Tomography

Ou Tan, Liang Liu, Xinbo Zhang, John C. Morrison, David Huang
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT438-OCT443

Gut Microbial Alterations Associated with Protection from Autoimmune Uveitis

Yukiko K. Nakamura, Christina Metea, Lisa Karstens, Mark Asquith, Henry Gruner, Cathleen Moscibrocki, Iris Lee, Colin J. Brislawn, Janet K. Jansson, James T. Rosenbaum, Phoebe Lin
Invest. Ophthalmol. Vis. Sci. 2016;57(8):3747-3758

Impact of Microscope-Integrated OCT on Ophthalmology Resident Performance of Anterior Segment Surgical Maneuvers in Model Eyes

Bozho Todorich, Christine Shieh, Philip J. DeSouza, Oscar M. Carrasco-Zevallos, David L. Cunefare, Sandra S. Stinnett, Joseph A. Izatt, Sina Farsiu, Privthi Mruthyunjaya, Anthony N. Kuo, Cynthia A. Toth Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT146-OCT153

Intracameral Antibiotics and Cataract Surgery: Endophthalmitis Rates, Costs, and Stewardship

Schwartz, Stephen G.Flynn, Harry W.Grzybowski, AndrzejRelhan, NidhiFerris, Frederick L. et al.
Ophthalmology, Volume 123, Issue 7, 1411 – 1413

In Vivo Imaging of Corneal Endothelial Dystrophy in Boston Terriers: A Spontaneous, Canine Model for Fuchs' Endothelial Corneal Dystrophy

Sara M. Thomasy, Dennis E. Cortes, Alyssa L. Hoehn, Allison C. Calderon, Jennifer Y. Li, Christopher J. Murphy
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT495-OCT503

Long-Term Protection of Retinal Ganglion Cells and Visual Function by Brain-Derived Neurotrophic Factor in Mice with Ocular Hypertension

Liang Feng, Hui Chen, Ji Yi, John B. Troy, Hao F. Zhang, Xiaorong Liu 
Invest. Ophthalmol. Vis. Sci. 2016;57(8):3793-3802

Manifestations of Complement-Mediated and Immune Complex-Mediated Membranoproliferative Glomerulonephritis

Dalvin, Lauren A. et al.
Ophthalmology, Volume 123, Issue 7, 1588 – 1594

Molecular and Clinical Findings in Patients with Knobloch Syndrome

Hull S, Arno G, Ku CA, Ge Z, Waseem N, Chandra A, Webster AR, Robson AG, Michaelides M, Weleber RG, Davagnanam I, Chen R, Holder GE, Pennesi ME, Moore AT.
JAMA Ophthalmol. 2016;134(7):753-762

Mortality in Older Persons with Retinopathy and Concomitant Health Conditions

Fisher, Diana E. et al.
Ophthalmology, Volume 123, Issue 7, 1570 – 1580

Optical Coherence Tomography Angiography

Simon S. Gao, Yali Jia, Miao Zhang, Johnny P. Su, Gangjun Liu, Thomas S. Hwang, Steven T. Bailey, David Huang
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT27-OCT36

Optic Nerve Head Measurements with Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

Anant Agrawal, Jigesh Baxi, William Calhoun, Chieh-Li Chen, Hiroshi Ishikawa, Joel S. Schuman, Gadi Wollstein, Daniel X. Hammer
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT413-OCT420

Outer Retinal Changes Including the Ellipsoid Zone Band in Usher Syndrome 1B due to MYO7A Mutations

Alexander Sumaroka, Rodrigo Matsui, Artur V. Cideciyan, David B. McGuigan, III, Rebecca Sheplock, Sharon B. Schwartz, Samuel G. Jacobson
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT253-OCT261

Posterior Eye Shape Measurement with Retinal OCT Compared to MRI

Anthony N. Kuo, Pavan K. Verkicharla, Ryan P. McNabb, Carol Y. Cheung, Saima Hilal, Sina Farsiu, Christopher Chen, Tien Y. Wong, M. Kamran Ikram, Ching Y. Cheng, Terri L. Young, Seang M. Saw, Joseph A. Izatt
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT196-OCT203

Prevalence and Causes of Visual Impairment and Blindness in Chinese American Adults: The Chinese American Eye Study

Varma R, Kim JS, Burkemper BS, Wen G, Torres M, Hsu C, Choudhury F, Azen SP, McKean-Cowdin R. JAMA Ophthalmol. 2016;134(7):785-793

Prognostic Implications of Tumor Diameter in Association with Gene Expression Profile for Uveal Melanoma

Walter SD, Chao DL, Feuer W, Schiffman J, Char DH, Harbour JW.
JAMA Ophthalmol. 2016;134(7):734-740

Proptosis in a Healthy Young Woman

Francis AW, Setabutr P, Aakalu V.
JAMA Ophthalmol. 2016;134(7):837-838

Quantifying Microvascular Density and Morphology in Diabetic Retinopathy Using Spectral-Domain Optical Coherence Tomography Angiography

Alice Y. Kim, Zhongdi Chu, Anoush Shahidzadeh, Ruikang K. Wang, Carmen A. Puliafito, Amir H. Kashani
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT362-OCT370

Quantitative Analysis of the Displacement of the Anterior Visual Pathway by Pituitary Lesions and the Associated Visual Field Loss

Michael V. Boland, In Ho Lee, Elcin Zan, David M. Yousem, Neil R. Miller
Invest. Ophthalmol. Vis. Sci. 2016;57(8):3576-3580

Quantitative Assessment of Anterior Segment Inflammation in a Rat Model of Uveitis Using Spectral-Domain Optical Coherence Tomography

Kathryn L. Pepple, Woo June Choi, Leslie Wilson, Russell N. Van Gelder, Ruikang K. Wang
Invest. Ophthalmol. Vis. Sci.2016;57(8):3567-3575

Relationship between Retinal Perfusion and Retinal Thickness in Healthy Subjects: An Optical Coherence Tomography Angiography Study

Jian Yu, Ruiping Gu, Yuan Zong, Huan Xu, Xiaolei Wang, Xinghuai Sun, Chunhui Jiang, Bing Xie, Yali Jia, David Huang
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT204-OCT210

Retinal Blood Flow Response to Hyperoxia Measured with En Face Doppler Optical Coherence Tomography

Alex D. Pechauer, Ou Tan, Liang Liu, Yali Jia, Vivian Hou, William Hills, David Huang
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT141-OCT145

Retinal Ganglion Cell Layer Thinning within One Month of Presentation for Non-Arteritic Anterior Ischemic Optic Neuropathy

Mark J. Kupersmith, Mona K. Garvin, Jui-Kai Wang, Mary Durbin, Randy Kardon
Invest. Ophthalmol. Vis. Sci. 2016;57(8):3588-3593

Retinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-Antagonist

Coyner AS, Ryals RC, Ku CA, Fischer CM, Patel RC, et al.
PLoS ONE 11(7): e0159776

Structural Change can be Detected in Advanced-Glaucoma Eyes

Akram Belghith, Felipe A. Medeiros, Christopher Bowd, Jeffrey M. Liebmann, Christopher A. Girkin, Robert N. Weinreb, Linda M. Zangwill
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT511-OCT518

The Feasibility of Spectral-Domain Optical Coherence Tomography Grading of Anterior Chamber Inflammation in a Rabbit Model of Anterior Uveitis

Michaela Edmond, Alex Yuan, Brent A. Bell, Amit Sharma, Rose M. DiCicco, Lauren Tucker, James Bena, Yuankai K. Tao, Sunil K. Srivastava
Invest. Ophthalmol. Vis. Sci. 2016;57(9):OCT184-OCT188

The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma

Ricardo Y. Abe, Alberto Diniz-Filho, Linda M. Zangwill, Carolina P. B. Gracitelli, Amir H. Marvasti, Robert N. Weinreb, Saif Baig, Felipe A. Medeiros
Invest. Ophthalmol. Vis. Sci.2016;57(9):OCT421-OCT428

Topical 5-Fluorouracil 1% as Primary Treatment for Ocular Surface Squamous Neoplasia

Joag, Madhura G. et al.
Ophthalmology, Volume 123, Issue 7, 1442 – 1448

Ultrafast Ultrasound Imaging of Ocular Anatomy and Blood Flow

Raksha Urs, Jeffrey A. Ketterling, Ronald H. Silverman
Invest. Ophthalmol. Vis. Sci. 2016;57(8):3810-3816

UV-A Protection from Auto Glass, Cataracts, and the Ophthalmologist

Weiss JS.
JAMA Ophthalmol.2016;134(7):776-777

Visual Impairment and Blindness in Adults in the United States: Demographic and Geographic Variations from 2015 to 2050

Varma R, Vajaranant TS, Burkemper B, Wu S, Torres M, Hsu C, Choudhury F, McKean-Cowdin R.
JAMA Ophthalmol. 2016;134(7):802-809


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