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Research to Prevent Blindness

2015 New Research - October

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Adaptive Optics Imaging of Retinal Photoreceptors Overlying Lesions in White Dot Syndrome and its Functional Correlation

Agarwal, Aniruddha et al.
American Journal of Ophthalmology, Volume 160, Issue 4, 806 - 816.e2

A Novel ImageJ Macro for Automated Cell Death Quantitation in the Retina

Daniel E. Maidana, Pavlina Tsoka, Bo Tian, Bernard Dib, Hidetaka Matsumoto, Keiko Kataoka, Haijiang Lin, Joan W. Miller, Demetrios G. Vavvas
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6701-6708

A Portable Platform for Evaluation of Visual Performance in Glaucoma Patients

Rosen PN, Boer ER, Gracitelli CPB, Abe RY, Diniz-Filho A, et al. 
PLoS ONE 10(10): e0139426

Assessment of Durability of Online and Multisensory Learning Using an Ophthalmology Model

Lippa, Linda Mottow et al.
Ophthalmology, Volume 122, Issue 10, 1960 – 1966

Association between Body Levels of Trace Metals and Glaucoma Prevalence

Lin S, Singh K, Lin SC.
JAMA Ophthalmol. 2015;133(10):1144-1150

Association between Vitamin D Status and Age-Related Macular Degeneration by Genetic Risk

Millen AE, Meyers KJ, Liu Z, et al.
JAMA Ophthalmol. 2015;133(10):1171-1179

Association of Compounded Bevacizumab with Postinjection Endophthalmitis

VanderBeek BL, Bonaffini SG, Ma L.
JAMA Ophthalmol. 2015;133(10):1159-1164

Changes in Macular Pigment Optical Density and Serum Lutein Concentration in Japanese Subjects Taking Two Different Lutein Supplements

Obana A, Tanito M, Gohto Y, Okazaki S, Gellermann W, et al. 
PLoS ONE 10(10): e0139257

Comparison among Methods of Retinopathy Assessment (CAMRA) Study

Ryan, Martha E. et al.
Ophthalmology, Volume 122, Issue 10, 2038 – 2043

Compartmental Innervation of the Superior Oblique Muscle in Mammals

Alan Le, Vadims Poukens, Howard Ying, Daniel Rootman, Robert A. Goldberg, Joseph L. Demer
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6237-6246

Cone and Rod Loss in Stargardt Disease Revealed by Adaptive Optics Scanning Light Ophthalmoscopy

Song H, Rossi EA, Latchney L, et al.
JAMA Ophthalmol. 2015;133(10):1198-1203

Contralateral Clinically Unaffected Eyes of Patients with Unilateral Infectious Keratitis Demonstrate a Sympathetic Immune Response

Andrea Cruzat, Wolfgang A. Schrems, Laura M. Schrems-Hoesl, Bernardo M. Cavalcanti, Neda Baniasadi, Deborah Witkin, Deborah Pavan-Langston, Reza Dana, Pedram Hamrah
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6612-6620

Demand for Tertiary Eye Care Services in Developing Countries

Subburaman, Ganesh-Babu B. et al.
American Journal of Ophthalmology, Volume 160, Issue 4, 619 - 627.e1

Differentiation of Diabetic Macular Edema from Pseudophakic Cystoid Macular Edema by Spectral-Domain Optical Coherence Tomography

Marion R. Munk, Lee M. Jampol, Christian Simader, Wolfgang Huf, Tamara J. Mittermüller, Glenn J. Jaffe, Ursula Schmidt-Erfurth
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6724-6733

Efficacy of VIP as Treatment for Bacteria-Induced Keratitis against Multiple Pseudomonas aeruginosa Strains

Thomas W. Carion, Cody R. McWhirter, Daiyajot K. Grewal, Elizabeth A. Berger
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6932-6940

Endothelium Expression of Bcl-2 is Essential for Normal and Pathological Ocular Vascularization

Zaitoun IS, Johnson RP, Jamali N, Almomani R, Wang S, et al. 
PLoS ONE 10(10): e0139994

Epithelial Thinning in Limbal Stem Cell Deficiency

Chan, Eric H. et al.
American Journal of Ophthalmology, Volume 160, Issue 4, 669 - 677.e4

Erp29 Attenuates Cigarette Smoke Extract–Induced Endoplasmic Reticulum Stress and Mitigates Tight Junction Damage in Retinal Pigment Epithelial Cells

Chuangxin Huang, Joshua J. Wang, Guangjun Jing, Junhua Li, Chenjin Jin, Qiang Yu, Marek W. Falkowski, Sarah X. Zhang
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6196-6207

Expression Profiling of Human Schlemm's Canal Endothelial Cells from Eyes with and without Glaucoma

Jingwen Cai, Kristin M. Perkumas, Xuejun Qin, Michael A. Hauser, W. Daniel Stamer, Yutao Liu
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6747-6753

Impact of Corneal Endothelial Dysfunctions on Intraocular Oxygen Levels in Human Eyes

Andrew J. W. Huang, Ying-Bo Shui, Yu-Ping Han, Fang Bai, Carla J. Siegfried, David C. Beebe
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6483-6488

Inferring an Evolutionary Tree of Uveal Melanoma from Genomic Copy Number Aberrations

Nakul Singh, Arun D. Singh, Winston Hide
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6801-6809

Inner Retinal Oxygen Extraction Fraction in Response to Light Flicker Stimulation in Humans

Anthony E. Felder, Justin Wanek, Norman P. Blair, Mahnaz Shahidi
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6633-6637

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina using the ERAI Reporter Mouse

Marcel V. Alavi, Wei-Chieh Chiang, Heike Kroeger, Douglas Yasumura, Michael T. Matthes, Takao Iwawaki, Matthew M. LaVail, Douglas B. Gould, Jonathan H. Lin
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6961-6970

Just Because It's Published Doesn't Mean It's Perfect

Bartley, George B.Liesegang, Thomas J. et al.
Ophthalmology, Volume 122, Issue 10, 1958 – 1959

Limbal Basal Cell Density Decreases in Limbal Stem Cell Deficiency

Chan, Eric H. et al.
American Journal of Ophthalmology, Volume 160, Issue 4, 678 - 684.e4

Multimodal Imaging of Central Retinal Disease Progression in a 2-Year Mean Follow-up of Retinitis Pigmentosa

Sujirakul, Tharikarn et al.
American Journal of Ophthalmology, Volume 160, Issue 4, 786 - 798.e4

Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype

Plog S, Klymiuk N, Binder S, Van Hook MJ, Thoreson WB, et al. 
PLoS ONE 10(10): e0140050

Neuroprotective Effects of Voluntary Exercise in an Inherited Retinal Degeneration Mouse Model

Adam M. Hanif, Eric C. Lawson, Megan Prunty, Marissa Gogniat, Moe H. Aung, Ranjay Chakraborty, Jeffrey H. Boatright, Machelle T. Pardue
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6839-6846

Optical Coherence Tomographic Angiography of Choroidal Neovascularization Associated with Central Serous Chorioretinopathy

McClintic SM, Jia Y, Huang D, Bailey ST.
JAMA Ophthalmol. 2015;133(10):1212-1214

Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degeneration

Kuehlewein, Laura et al.
American Journal of Ophthalmology, Volume 160, Issue 4, 739 - 748.e2

Outcomes of an Algorithmic Approach to Treating Mild Ocular Alkali Burns

Al-Moujahed A, Chodosh J.
JAMA Ophthalmol. 2015;133(10):1214-1216

Pathological Effects of Mutant C1QTNF5 (S163R) Expression in Murine Retinal Pigment Epithelium

Astra Dinculescu, Seok-Hong Min, Frank M. Dyka, Wen-Tao Deng, Rachel M. Stupay, Vince Chiodo, W. Clay Smith, William W. Hauswirth
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6971-6980

Patterns of Glaucoma Medication Adherence over Four Years of Follow-Up

Newman-Casey, Paula Anne et al.
Ophthalmology, Volume 122, Issue 10, 2010 – 2021

Predicting Risk of Motor Vehicle Collisions in Patients with Glaucoma: A Longitudinal Study

Gracitelli CPB, Tatham AJ, Boer ER, Abe RY, Diniz-Filho A, et al. 
PLoS ONE 10(10): e0138288

Rare Variants in the Functional Domains of Complement Factor H are Associated with Age-Related Macular Degeneration

Michael P. Triebwasser, Elisha D. O. Roberson, Yi Yu, Elizabeth C. Schramm, Erin K. Wagner, Soumya Raychaudhuri, Johanna M. Seddon, John P. Atkinson
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6873-6878

Residual and Dynamic Range of Retinal Nerve Fiber Layer Thickness in Glaucoma: Comparison of Three OCT Platforms

Jean-Claude Mwanza, Hanna Y. Kim, Donald L. Budenz, Joshua L. Warren, Michael Margolis, Scott D. Lawrence, Pooja D. Jani, Garrett S. Thompson, Richard K. Lee
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6344-6351

Rhodopsin Forms Nanodomains in Rod Outer Segment Disc Membranes of the Cold-Blooded Xenopus laevis

Rakshit T, Senapati S, Sinha S, Whited AM, Park PS-H 
PLoS ONE 10(10): e0141114

Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice

Mao Mao, Richard S. Smith, Marcel V. Alavi, Jeffrey K. Marchant, Mihai Cosma, Richard T. Libby, Simon W. M. John, Douglas B. Gould
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6823-6831

Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice

Bruce A. Berkowitz, Timothy S. Kern, David Bissig, Priya Patel, Ankit Bhatia, Vladimir J. Kefalov, Robin Roberts
Invest. Ophthalmol. Vis. Sci. 2015;56(11):6294-6303

The Risk of Intraocular Pressure Elevation in Pediatric Noninfectious Uveitis

Kothari, Srishti et al.
Ophthalmology, Volume 122, Issue 10, 1987 – 2001

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