Research Archive

Changes in Relative Position of Choroidal Versus Retinal Vessels in Preterm Infants

Sang Jin Kim, J. Peter Campbell, Susan Ostmo, Karyn E. Jonas, R. V. Paul Chan, Michael F. Chiang, for the Imaging and Informatics in Retinopathy of Prematurity (i-ROP) Research Consortium
Invest. Ophthalmol. Vis. Sci. 2017;58(14):6334-6341

Mouse models of human ocular disease for translational research

Krebs MP, Collin GB, Hicks WL, Yu M, Charette JR, et al.
PLOS ONE 12(8): e0183837

Influence of Computer-Generated Mosaic Photographs on Retinopathy of Prematurity Diagnosis and Management

Patel SN, Klufas MA, Douglas CE, Jonas KE, Ostmo S, Berrocal A, Capone A, Martinez-Castellanos MA, Chau F, Drenser K, Ferrone P, Orlin A, Tsui I, Wu W, Gupta MP, Chiang MF, Chan RVP, for the i-ROP Research Consortium
JAMA Ophthalmol. 2016;134(11):1283-1289

Surveillance Tools Emerging from Search Engines and Social Media Data for Determining Eye Disease Patterns

Deiner MS, Lietman TM, McLeod SD, Chodosh J, Porco TC.
JAMA Ophthalmol. 2016;134(9):1024-1030

Evaluating the Validity of the Age-Related Eye Disease Study Grading Scale for Age-Related Macular DegenerationAREDS2 Report 10

Vitale S, Clemons TE, Agrón E, Ferris FL, Domalpally A, Danis RP, Chew EY, for the Age-Related Eye Disease Study 2 (AREDS2) Research Group
JAMA Ophthalmol. 2016;134(9):1041-1047

Simultaneous Recordings of Human Microsaccades and Drifts with a Contemporary Video Eye Tracker and the Search Coil Technique

McCamy MB, Otero-Millan J, Leigh RJ, King SA, Schneider RM, et al.
PLoS ONE 10(6): e0128428

Subvoxel Accurate Graph Search Using Non-Euclidean Graph Space.

Abràmoff MD, Wu X, Lee K, Tang L
PLoS ONE, October 2014, 9(10): e107763.

Collaborative Retrospective Macula Society Study of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Jennifer I. Lim, Adam R. Glassman, Lloyd Paul Aiello, Usha Chakravarthy, Christina J. Flaxel, Richard F. Spaide, Macula Society CSC Collaborative Study Group, Research and Education Committee and Website Committee
Ophthalmology - May 2014 (Vol. 121, Issue 5, Pages 1073-1078)

Characterizing Functional Complaints in Patients Seeking Outpatient Low-Vision Services in the United States

Jamie C. Brown, Judith E. Goldstein, Tiffany L. Chan, Robert Massof, Pradeep Ramulu, Low Vision Research Network Study Group*
Ophthalmology
April 2014 (10.1016/j.ophtha.2014.02.030)

Visual Acuity after Cataract Surgery in Patients with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report Number 5

Age-Related Eye Disease Study 2 Research Group, Writing Committee, Nancy Huynh, Benjamin P. Nicholson, Elvira Agrón, Traci E. Clemons, Susan B. Bressler, Philip J. Rosenfeld, Emily Y. Chew
Ophthalmology
March 2014 (10.1016/j.ophtha.2013.12.035)

Randomized Trial of a Home Monitoring System for Early Detection of Choroidal Neovascularization Home Monitoring of the Eye (HOME) Study

The AREDS2-HOME Study Research Group, Emily Y. Chew, Traci E. Clemons, Susan B. Bressler, Michael J. Elman, Ronald P. Danis, Amitha Domalpally, Jeffrey S. Heier, Judy E. Kim, Richard Garfinkel
Ophthalmology
February 2014 (Vol. 121, Issue 2, Pages 535-544)

Collaborative Retrospective Macula Society Study of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Jennifer I. Lim, Adam R. Glassman, Lloyd Paul Aiello, Usha Chakravarthy, Christina J. Flaxel, Richard F. Spaide, Macula Society CSC Collaborative Study Group, Research and Education Committee and Website Committee
Ophthalmology
January 2014 (10.1016/j.ophtha.2013.11.040)

Validity of Self-Report in Type 1 Diabetic Subjects for Laser Treatment of Retinopathy

Michael A. Grassi, Wanjie Sun, Sapna Gangaputra, Patricia A. Cleary, Larry Hubbard, John M. Lachin, Xiaoyu Gao, Szilárd Kiss, Andrew J. Barkmeier, Arghavan Almony, Matthew Davis, Ronald Klein, Ronald P. Danis, DCCT/EDIC Research Group
Ophthalmology
December 2013 (Vol. 120, Issue 12, Pages 2580-2586)

Investigation of known genetic risk factors for primary open angle glaucoma in two populations of african ancestry.

Liu Y, Hauser MA, Akafo SK, Qin X, Miura S, Gibson JR, Wheeler J, Gaasterland DE, Challa P, Herndon LW, the International Consortium of African Ancestry REsearch in Glaucoma, Ritch R, Moroi SE, Pasquale LR, Girkin CA, Budenz DL, Wiggs JL, Richards JE, Ashley-Koch AE, Allingham RR.
Investigative Ophthalmology & Visual Science 2013;54:6248-6254.

Characteristics of Incident Geographic Atrophy in the Complications of Age-Related Macular Degeneration Prevention Trial

Hilary Smolen Brader, Gui-shuang Ying, E. Revell Martin, Maureen G. Maguire, Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group
Ophthalmology
September 2013 (Vol. 120, Issue 9, Pages 1871-1879)

Risk of Elevated Intraocular Pressure and Glaucoma in Patients with Uveitis: Results of the Multicenter Uveitis Steroid Treatment Trial

David S. Friedman, Janet T. Holbrook, Husam Ansari, Judith Alexander, Alyce Burke, Susan B. Reed, Joanne Katz, Jennifer E. Thorne, Susan L. Lightman, John H. Kempen, MUST Research Group
Ophthalmology
August 2013 (Vol. 120, Issue 8, Pages 1571-1579)

Validity of Self-Report in Type 1 Diabetic Subjects for Laser Treatment of Retinopathy

Michael A. Grassi, Wanjie Sun, Sapna Gangaputra, Patricia A. Cleary, Larry Hubbard, John M. Lachin, Xiaoyu Gao, Szilárd Kiss, Andrew J. Barkmeier, Arghavan Almony, Matthew Davis, Ronald Klein, Ronald P. Danis, DCCT/EDIC Research Group
Ophthalmology
July 2013 (10.1016/j.ophtha.2013.06.002)

Risk of Elevated Intraocular Pressure and Glaucoma in Patients with Uveitis: Results of the Multicenter Uveitis Steroid Treatment Trial

David S. Friedman, Janet T. Holbrook, Husam Ansari, Judith Alexander, Alyce Burke, Susan B. Reed, Joanne Katz, Jennifer E. Thorne, Susan L. Lightman, John H. Kempen, MUST Research Group
Ophthalmology
April 2013 (10.1016/j.ophtha.2013.01.025)

Characteristics of Incident Geographic Atrophy in the Complications of Age-Related Macular Degeneration Prevention Trial

Hilary Smolen Brader, Gui-shuang Ying, E. Revell Martin, Maureen G. Maguire, Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group
Ophthalmology
April 2013 (10.1016/j.ophtha.2013.01.049)

Non-cytomegalovirus Ocular Opportunistic Infections in Patients With Acquired Immunodeficiency Syndrome

Sapna Gangaputra, Lea Drye, Vijay Vaidya, Jennifer E. Thorne, Douglas A. Jabs, Alice T. Lyon, Studies of the Ocular Complications of AIDS (SOCA) Research Group
American Journal of Ophthalmology
February 2013 (Vol. 155, Issue 2, Pages 206-212.e5)

Randomized Clinical Trial Evaluating Intravitreal Ranibizumab or Saline for Vitreous Hemorrhage From Proliferative Diabetic Retinopathy

Diabetic Retinopathy Clinical Research Network*
JAMA Ophthalmol. 2013;():1-11.

Risk Factors for Loss of Visual Acuity among Patients with Uveitis Associated with Juvenile Idiopathic Arthritis: The Systemic Immunosuppressive Therapy for Eye Diseases Study

Anthony C. Gregory, John H. Kempen, Ebenezer Daniel, R. Oktay Kaçmaz, C. Stephen Foster, Douglas A. Jabs, Grace A. Levy-Clarke, Robert B. Nussenblatt, James T. Rosenbaum, Eric B. Suhler, Jennifer E. Thorne, Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study Research Group
Ophthalmology
January 2013 (Vol. 120, Issue 1, Pages 186-192)

Risk of Cataract in Persons with Cytomegalovirus Retinitis and the Acquired Immune Deficiency Syndrome

John H. Kempen, Elizabeth A. Sugar, Alice T. Lyon, Richard Alan Lewis, Douglas A. Jabs, Murk-Hein Heinemann, James P. Dunn, Studies of Ocular Complications of AIDS Research Group
Ophthalmology
November 2012 (Vol. 119, Issue 11, Pages 2343-2350)

Non-cytomegalovirus Ocular Opportunistic Infections in Patients With AIDS

Sapna Gangaputra, Lea Drye, Vijay Vaidya, Jennifer E. Thorne, Douglas A. Jabs, Alice T. Lyon, Studies of the Ocular Complications of AIDS (SOCA) Research Group
American Journal of Ophthalmology
October 2012 (10.1016/j.ajo.2012.07.019)

The Association of Consumption of Fruits/Vegetables With Decreased Risk of Glaucoma Among Older African-American Women in the Study of Osteoporotic Fractures

Joann A. Giaconi, Fei Yu, Katie L. Stone, Kathryn L. Pedula, Kristine E. Ensrud, Jane A. Cauley, Marc C. Hochberg, Anne L. Coleman, Study of Osteoporotic Fractures Research Group
American Journal of Ophthalmology
October 2012 (Vol. 154, Issue 4, Pages 635-644)

Risk Factors for Loss of Visual Acuity among Patients with Uveitis Associated with Juvenile Idiopathic Arthritis: The Systemic Immunosuppressive Therapy for Eye Diseases Study

Anthony C. Gregory, John H. Kempen, Ebenezer Daniel, R. Oktay Kaçmaz, C. Stephen Foster, Douglas A. Jabs, Grace A. Levy-Clarke, Robert B. Nussenblatt, James T. Rosenbaum, Eric B. Suhler, Jennifer E. Thorne, Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study Research Group
Ophthalmology
October 2012 (10.1016/j.ophtha.2012.07.052)

Baseline Traits of Low Vision Patients Served by Private Outpatient Clinical Centers in the United States

Judith E. Goldstein, OD, Robert W. Massof, PhD, James T. Deremeik, CLVT, Sonya Braudway, OD, Mary Lou Jackson, MD, K. Bradley Kehler, OD, Susan A. Primo, OD, MPH, Janet S. Sunness, MD, for the Low Vision Research Network Study Group
Arch Ophthalmol. 2012;130(8):1028-1037.

Risk of Corticosteroid-Induced Hyperglycemia Requiring Medical Therapy among Patients with Inflammatory Eye Diseases

Joshua D. Udoetuk, Yang Dai, Gui-Shuang Ying, Ebenezer Daniel, Sapna Gangaputra, James T. Rosenbaum, Eric B. Suhler, Jennifer E. Thorne, C. Stephen Foster, Douglas A. Jabs, Grace A. Levy-Clarke, Robert B. Nussenblatt, John H. Kempen, Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study Research Group
Ophthalmology
August 2012 (Vol. 119, Issue 8, Pages 1569-1574)

The Association of Consumption of Fruits/Vegetables With Decreased Risk of Glaucoma Among Older African-American Women in the Study of Osteoporotic Fractures

Joann A. Giaconi, Fei Yu, Katie L. Stone, Kathryn L. Pedula, Kristine E. Ensrud, Jane A. Cauley, Marc C. Hochberg, Anne L. Coleman, Study of Osteoporotic Fractures Research Group
American Journal of Ophthalmology
July 2012 (10.1016/j.ajo.2012.03.048)

Risk of Cataract in Persons with Cytomegalovirus Retinitis and the Acquired Immune Deficiency Syndrome

John H. Kempen, Elizabeth A. Sugar, Alice T. Lyon, Richard Alan Lewis, Douglas A. Jabs, Murk-Hein Heinemann, James P. Dunn, Studies of Ocular Complications of AIDS Research Group*
Ophthalmology
July 2012 (10.1016/j.ophtha.2012.05.044)

Incidence of Cytomegalovirus Retinitis in the Era of Highly Active Antiretroviral Therapy

Elizabeth A. Sugar, Douglas A. Jabs, Alka Ahuja, Jennifer E. Thorne, Ronald P. Danis, Curtis L. Meinert, Studies of the Ocular Complications of AIDS Research Group
American Journal of Ophthalmology
June 2012 (Vol. 153, Issue 6, Pages 1016-1024.e5)

Retinal Vessel Caliber Among People With Acquired Immunodeficiency Syndrome: Relationships With Visual Function

Partho S. Kalyani, Amani A. Fawzi, Sapna Gangaputra, Mark L. van Natta, Larry D. Hubbard, Ronald P. Danis, Jennifer E. Thorne, Gary N. Holland, Studies of the Ocular Complications of AIDS Research Group
American Journal of Ophthalmology
March 2012 (Vol. 153, Issue 3, Pages 428-433.e1)

Retinal Vessel Caliber Among People With Acquired Immunodeficiency Syndrome: Relationships With Disease-Associated Factors and Mortality

Sapna Gangaputra, Partho S. Kalyani, Amani A. Fawzi, Mark L. Van Natta, Larry D. Hubbard, Ronald P. Danis, Jennifer E. Thorne, Gary N. Holland, Studies of the Ocular Complications of AIDS Research Group
American Journal of Ophthalmology
March 2012 (Vol. 153, Issue 3, Pages 434-444.e1)

Associations among Visual Acuity and Vision- and Health-Related Quality of Life among Patients in the Multicenter Uveitis Steroid Treatment Trial

Kevin D. Frick, Lea T. Drye, John H. Kempen, James P. Dunn, Gary N. Holland, Paul Latkany, Narsing A. Rao, H. Nida Sen, Elizabeth A. Sugar, Jennifer E. Thorne, Robert C. Wang, Janet T. Holbrook, and for the Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group
IOVS March 2012 53:1169-1176.

Identifying a Clinically Meaningful Threshold for Change in Uveitic Macular Edema Evaluated by Optical Coherence Tomography

Elizabeth A. Sugar, Douglas A. Jabs, Michael M. Altaweel, Sue Lightman, Nisha Acharya, Albert T. Vitale, Jennifer E. Thorne, Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group
American Journal of Ophthalmology
December 2011 (Vol. 152, Issue 6, Pages 1044-1052.e5)

New Grading Criteria Allow for Earlier Detection of Geographic Atrophy in Clinical Trials

Hilary Smolen Brader, Gui-shuang Ying, E. Revell Martin, Maureen G. Maguire, and the Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group
Invest. Ophthalmol. Vis. Sci. 2011 52:9218-9225.

Retinal Vessel Caliber Among People With Acquired Immunodeficiency Syndrome: Relationships With Visual Function

Partho S. Kalyani, Amani A. Fawzi, Sapna Gangaputra, Mark L. van Natta, Larry D. Hubbard, Ronald P. Danis, Jennifer E. Thorne, Gary N. Holland, Studies of the Ocular Complications of Aids Research Group
American Journal of Ophthalmology
October 2011 (10.1016/j.ajo.2011.08.027)

Retinal Vessel Caliber Among People With Acquired Immunodeficiency Syndrome: Relationships With Disease-Associated Factors and Mortality

Sapna Gangaputra, Partho S. Kalyani, Amani A. Fawzi, Mark L. van Natta, Larry D. Hubbard, Ronald P. Danis, Jennifer E. Thorne, Gary N. Holland, Studies of the Ocular Complications of Aids Research Group
American Journal of Ophthalmology
October 2011 (10.1016/j.ajo.2011.08.028)

Evaluation of the United States Public Health Service Guidelines for Discontinuation of Anticytomegalovirus Therapy After Immune Recovery in Patients With Cytomegalovirus Retinitis

Janet T. Holbrook, Ryan Colvin, Mark L. van Natta, Jennifer E. Thorne, Mark Bardsley, Douglas A. Jabs, Studies of Ocular Complications of AIDS (SOCA) Research Group
American Journal of Ophthalmology
October 2011 (Vol. 152, Issue 4, Pages 628-637.e1)

Randomized Comparison of Systemic Anti-inflammatory Therapy Versus Fluocinolone Acetonide Implant for Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment Trial

The Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Writing Committee, John H. Kempen, Michael M. Altaweel, Janet T. Holbrook, Douglas A. Jabs, Thomas A. Louis, Elizabeth A. Sugar, Jennifer E. Thorne
Ophthalmology
October 2011 (Vol. 118, Issue 10, Pages 1916-1926)

Understanding and Reporting Visual Acuity Measurements in Publications of Clinical Research

Mariana S. Lopes; Shiri Zayit-Soudry; Ala Moshiri; Susan B. Bressler; Neil M. Bressler
Arch Ophthalmol, Sep 2011; 129: 1228-1229.

Candidate Gene Association Study for Diabetic Retinopathy in Persons with Type 2 Diabetes: The Candidate Gene Association Resource (CARe)

Lucia Sobrin, Todd Green, Xueling Sim, Richard A. Jensen, E. Shyong Tai, Wan Ting Tay, Jie Jin Wang, Paul Mitchell, Niina Sandholm, Yiyuan Liu, Kustaa Hietala, Sudha K. Iyengar, for the Family Investigation of Nephropathy and Diabetes-Eye Research Group, Matthew Brooks, Monika Buraczynska, Natalie Van Zuydam, Albert V. Smith, Vilmundur Gudnason, Alex S. F. Doney, Andrew D. Morris, Graham P. Leese, Colin N. A. Palmer, for the Wellcome Trust Case Control Consortium 2, Anand Swaroop, Herman A. Taylor, Jr, James G. Wilson, Alan Penman, Ching J. Chen, Per-Henrik Groop, Seang-Mei Saw, Tin Aung, Barbara E. Klein, Jerome I. Rotter, David S. Siscovick, Mary Frances Cotch, Ronald Klein, Mark J. Daly, and Tien Y. Wong
Invest. Ophthalmol. Vis. Sci. 2011 52:7593-7602.

Identifying a Clinically Meaningful Threshold for Change in Uveitic Macular Edema Evaluated by Optical Coherence Tomography

Elizabeth A. Sugar, Douglas A. Jabs, Michael M. Altaweel, Sue Lightman, Nisha Acharya, Albert T. Vitale, Jennifer E. Thorne, Multicenter Uveitis Steroid Treatment (must) Trial Research Group
American Journal of Ophthalmology
August 2011 (10.1016/j.ajo.2011.05.028)

Randomized Comparison of Systemic Anti-inflammatory Therapy Versus Fluocinolone Acetonide Implant for Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment Trial

The Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Writing Committee, John H. Kempen, Michael M. Altaweel, Janet T. Holbrook, Douglas A. Jabs, Thomas A. Louis, Elizabeth A. Sugar, Jennifer E. Thorne
Ophthalmology
August 2011 (10.1016/j.ophtha.2011.07.027)

Evaluation of the United States Public Health Service Guidelines for Discontinuation of Anticytomegalovirus Therapy after Immune Recovery in Patients with Cytomegalovirus Retinitis

Janet T. Holbrook, Ryan Colvin, Mark L. van Natta, Jennifer E. Thorne, Mark Bardsley, Douglas A. Jabs, Studies of Ocular Complications of Aids (soca) Research Group
American Journal of Ophthalmology
July 2011 (10.1016/j.ajo.2011.04.007)

Corneal Dystrophies: Molecular Genetics to Therapeutic Intervention—Fifth ARVO/Pfizer Ophthalmics Research Institute Conference

Jayne S. Weiss and the Fifth ARVO/Pfizer Ophthalmics Research Institute Conference Working Group
Invest. Ophthalmol. Vis. Sci. 2010 51: 5391-5402.

Ophthalmic Drug Delivery Systems for the Treatment of Retinal Diseases: Basic Research to Clinical Applications

Henry F. Edelhauser, Cheryl L. Rowe-Rendleman, Michael R. Robinson, Daniel G. Dawson, Gerald J. Chader, Hans E. Grossniklaus, Kay D. Rittenhouse, Clive G. Wilson, David A. Weber, Baruch D. Kuppermann, Karl G. Csaky, Timothy W. Olsen, Uday B. Kompella, V. Michael Holers, Gregory S. Hageman, Brian C. Gilger, Peter A. Campochiaro, Scott M. Whitcup, and Wai T. Wong
Invest. Ophthalmol. Vis. Sci. 2010 51: 5403-5420.

Digital versus Film Fundus Photography for Research Grading of Diabetic Retinopathy Severity

Helen K. Li, Larry D. Hubbard, Ronald P. Danis, Adol Esquivel, Jose F. Florez-Arango, Nicola J. Ferrier, and Elizabeth A. Krupinski
Invest. Ophthalmol. Vis. Sci. 2010 51: 5846-5852.

In Search of the Identity of the XAP-1 Antigen: A Protein Localized to Cone Outer Segments

Suba Nookala, Rohit Gandrakota, Amira Wohabrebbi, XiaoFei Wang, Danielle Howell, Francesco Giorgianni, Sarka Beranova-Giorgianni, Dominic M. Desiderio, and Monica M. Jablonski
Invest. Ophthalmol. Vis. Sci. 2010 51: 2736-2743.

The Multicenter Uveitis Steroid Treatment Trial: Rationale, Design, and Baseline Characteristics , 25 January 2010

The Multicenter Uveitis Steroid Treatment Trial Research Group
American Journal of Ophthalmology
April 2010 (Vol. 149, Issue 4, Pages 550-561.e10)

At the Frontier of Vision Research: The National Eye Institute Celebrates 40 Years

Paul A. Sieving
American Journal of Ophthalmology
1 February 2010 (Vol. 149, Issue 2, Pages 179-181)

The Multicenter Uveitis Steroid Treatment Trial: Rationale, Design, and Baseline Characteristics Corrected Proof, 25 January 2010

The Multicenter Uveitis Steroid Treatment Trial Research Group
American Journal of Ophthalmology
DOI: 10.1016/j.ajo.2009.11.019

The Association of Smoking and Alcohol Use With Age-related Macular Degeneration in the Oldest Old: The Study of Osteoporotic Fractures , 01 October 2009

Anne L. Coleman, Robin L. Seitzman, Steven R. Cummings, Fei Yu, Jane A. Cauley, Kristine E. Ensrud, Katie L. Stone, Marc C. Hochberg, Kathryn L. Pedula, Edgar L. Thomas, Carol M. Mangione, The Study Of Osteoporotic Fractures Research Group
American Journal of Ophthalmology
January 2010 (Vol. 149, Issue 1, Pages 160-169)

Statin Use and the Incidence of Advanced Age-related Macular Degeneration in the Complications of Age-related Macular Degeneration Prevention Trial , 22 October 2009

Maureen G. Maguire, Gui-shuang Ying, Colin A. McCannel, Chengcheng Liu, Yang Dai, Complications of Age-related Macular Degeneration Prevention Trial (CAPT) Research Group
Ophthalmology
December 2009 (Vol. 116, Issue 12, Pages 2381-2385)

Association Between Dietary Fat Intake and Age-Related Macular Degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS): An Ancillary Study of the Women's Health Initiative

Niyati Parekh; Rickie P. Voland; Suzen M. Moeller; Barbara A. Blodi; Cheryl Ritenbaugh; Richard J. Chappell; Robert B. Wallace; Julie A. Mares; for the CAREDS Research Study Group
Arch Ophthalmol, Nov 2009; 127: 1483 - 1493.

The Association of Smoking and Alcohol Use with Age-related Macular Degeneration in the Oldest Old: The Study of Osteoporotic Fractures Corrected Proof, 01 October 2009

Anne L. Coleman, Robin L. Seitzman, Steven R. Cummings, Fei Yu, Jane A. Cauley, Kristine E. Ensrud, Katie L. Stone, Marc C. Hochberg, Kathryn L. Pedula, Edgar L. Thomas, Carol M. Mangione, Study Of Osteoporotic Fractures Research Group
American Journal of Ophthalmology
DOI: 10.1016/j.ajo.2009.07.025

Intraocular Inflammation Associated with Ocular Toxoplasmosis: Relationships at Initial Examination

Emilio M. Dodds, Gary N. Holland, Miles R. Stanford, Fei Yu, Willie O. Siu, Kayur H. Shah, Ninette ten Dam-van Loon, Cristina Muccioli, Anna Hovakimyan, Talin Barisani-Asenbauer, International Ocular Toxoplasmosis Research Group
American Journal of Ophthalmology
December 2008 (Vol. 146, Issue 6, Pages 856-865.e2)

Drug Delivery to Posterior Intraocular Tissues: Third Annual ARVO/Pfizer Ophthalmics Research Institute Conference

Henry F. Edelhauser, Jeffrey H. Boatright, John M. Nickerson, and the Third ARVO/Pfizer Research Institute Working Group
Invest. Ophthalmol. Vis. Sci. 2008 49: 4712-4720.

Visual Fields at Follow-up in the Ischemic Optic Neuropathy Decompression Trial: Evaluation of Change in Pattern Defect and Severity Over Time , 16 May 2008

Roberta W. Scherer, Steven E. Feldon, Lori Levin, Patricia Langenberg, Joanne Katz, Penelope M. Keyl, P. David Wilson, Shalom E. Kelman, Kay Dickersin, Ischemic Optic Neuropathy Decompression Trial Research Group
Ophthalmology
October 2008 (Vol. 115, Issue 10, Pages 1809-1817)

Glaucoma Risk and the Consumption of Fruits and Vegetables Among Older Women in the Study of Osteoporotic Fractures , 27 February 2008

Anne L. Coleman, Katie L. Stone, Gergana Kodjebacheva, Fei Yu, Kathryn L. Pedula, Kris E. Ensrud, Jane A. Cauley, Marc C. Hochberg, Fotis Topouzis, Federico Badala, Carol M. Mangione, Study of Osteoporotic Fractures Research Group
American Journal of Ophthalmology
June 2008 (Vol. 145, Issue 6, Pages 1081-1089)

Retinal Precursors and the Development of Geographic Atrophy in Age-Related Macular Degeneration , 05 November 2007

Michael L. Klein, Frederick L. Ferris, Jane Armstrong, Thomas S. Hwang, Emily Y. Chew, Susan B. Bressler, Suresh R. Chandra, AREDS Research Group
Ophthalmology
June 2008 (Vol. 115, Issue 6, Pages 1026-1031)

Vision Function in HIV-Infected Individuals without Retinitis: Report of the Studies of Ocular Complications of AIDS Research Group , 27 November 2007

William R. Freeman, Mark L. Van Natta, Douglas Jabs, Pamela A. Sample, Alfredo A. Sadun, Jennifer Thorne, Kayur H. Shah, Gary N. Holland, SOCA Research Group
American Journal of Ophthalmology
March 2008 (Vol. 145, Issue 3, Pages 453-462.e1)

Retinal Precursors and the Development of Geographic Atrophy in Age-Related Macular Degeneration

Corrected Proof, 5 November 2007
Michael L. Klein, Frederick L. Ferris, Jane Armstrong, Thomas S. Hwang, Emily Y. Chew, Susan B. Bressler, Suresh R. Chandra, AREDS Research Group
Ophthalmology
DOI: 10.1016/j.ophtha.2007.08.030

Changes to euchromatin on LAT and ICP4 following reactivation are more prevalent in an efficiently reactivating strain of HSV-1

Creech CC, Neumann DM
PLoS ONE 2010;5(11):e15416 (Louisiana State Univ. Health Sciences Center School of Medicine – Unres. Grant) Keyword(s): Gene Research/Therapy, Uveitis/Infectious Diseases

Functional and behavioral restoration of vision by gene therapy in the guanylate cyclase-1 (GC1) knockout mouse

Boye SE, Boye SL, Pang J, Ryals R, Everhart D, Umino Y, Neeley AW, Besharse J, Barlow R, Hauswirth WW
PLoS ONE 2010;5(6):e11306 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy, Retina/Retinal Diseases

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL; Complications of Age-Related Macular Degeneration Prevention Trial Research Group, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris Iii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A
Proc Natl Acad Sci USA 2010;107(16):7401-7406 (Oregon Health & Science Univ. – Unres. Grant and Career Development Awd) Keyword(s): AMD, Gene Research/Therapy, Genetics

Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78

Gorbatyuk MS, Knox T, LaVail MM, Gorbatyuk OS, Noorwez SM, Hauswirth WW, Lin JH, Muzyczka N, Lewin AS
Proc Natl Acad Sci USA 2010;107(13):5961-5966 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy, Retina/Retinal Diseases

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL; Complications of Age-Related Macular Degeneration Prevention Trial Research Group, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris Iii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A
Proc Natl Acad Sci USA 2010;107(16):7401-7406 (Vanderbilt Univ. Medical Center – Unres. Grant) Keyword(s): AMD, Gene Research/Therapy, Genetics

Genetic variants near TIMP3 and high density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Yanming L, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz H, Brown WL, Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group, Brucker AJ, Orlin A, Brown G, Ho A, REgillo C, Donoso , Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BEK, Gotoh N, Yamashiro K, Ferris F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Corton M, Carracedo A, Sanchez-Salorio M, Puch EW, Doheny KF, Brion M, DeAngelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsansis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A
Proc Natl Acad Sci USA 2010;107(16):7401-7406 (Tufts Univ. - Unres. Grant) Keyword(s): AMD, Retina/Retinal Diseases

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL, Complications of Age-Related Macular Degeneration Prevention Trial Research Group, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris Iii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A
Proc Natl Acad Sci USA 2010;107(16):7401-7406 (Univ. of Miami - Unres. Grant) Keyword(s): Genetics, Retina/Retinal Diseases

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL; Complications of Age-Related Macular Degeneration Prevention Trial Research Group, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris lii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A
Proc Natl Acad Sci USA 2010;107(16):7401-7406 (Univ. of Pennsylvania – Unres Grant) Keyword(s): Gene Research/Therapy

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL; Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BEk, Gotoh N, Yamashiro K, Ferris III F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, DeAngelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR and Swaroop A
Proc Natl Acad Sci USA 2010;107(16):7401-7406 (Cleveland Clinic Lerner College of Medicine - Unres. Grant) Keyword(s): AMD, Genetics

Visual acuity in patients with leber’s congenital amaurosis and early childhood-onset retinitis pigmentosa

Walia S, Fishman GA, Jacobson SG, Aleman TS, Koenekoop RK, Traboulsi EI, Weleber RG, Pennesi ME, Heon E, Drak A, Lam BL, Allikmets R, Stone EM
Ophthalmology 2010;117(6):1190-1198 (Univ. of Pennsylvania – Unres. Grant) Keyword(s): Gene Research/Therapy

Visual acuity in patients with leber's congenital amaurosis and early childhood-onset retinitis pigmentosa

Walia S, Fishman GA, Jacobson SG, Aleman TS, Koenekoop RK, Traboulsi EI, Weleber RG, Pennesi ME, Heon E, Drack A, Lam BL, Allikmets R, Stone EM
Ophthalmology 2010;117(6):1190-1198 (Univ. of Iowa - Unres. Grant) Keyword(s): Gene Research/Therapy, Retinitis Pigmentosa

Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells

Lukiw WJ, Cui JG, Yuan LY, Bhattacharjee PS, Cockern M, Clement C, Kammerman EM, Ball MJ, Zhao Y, Sullivan PM, Hill JM
Neuroreport 2010;21(14):922-927 (Louisiana State Univ. Health Sciences Center School of Medicine – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Gene Research/Therapy, Uveitis/Infectious Diseases

Neuroprotective effect of over expression of thioredoxin on photoreceptor degeneration in tubby mice

Kong L, Zhou X, Li F, Yodoi J, McGinnis JF, Cao W
Neurobiol Dis 2010;38(3):446-455 (Univ. of Oklahoma Health Sciences Center – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): AMD, Diabetic Retinopathy, Gene Research/Therapy, Retina/Retinal Diseases, Retinitis Pigmentosa

Candidate genes for chromosomes 6 and 10 quantitative trait loci for age-related retinal degeneration in mice

Ogando DG, Dahlquist KD, Alizadeh M, Kunchithapautham K, Li J, Yu N, LaVail MM, Rohrer B, Vollrath D, Danciger M
Mol Vis 2010;16:1004-1018 (Medical Univ. of South Carolina – Unres. Grant and Olga Keith Weiss Scholar) Keyword(s): AMD, Gene Research/Therapy

Vector delivery technique affects gene transfer in the cornea in vivo

Mohan RR, Sharma A, Cebulko TC, Tandon A
Mol Vis 2010;16:2494-2501 (Univ. of Missouri – Unres. Grant) Keyword(s): Cornea, Gene Research/Therapy

Expression characteristics of dual-promoter lentiviral vectors targeting retinal photoreceptors and müller cells

Semple-Rowland SL, Coggin WE, Geesey M, Eccles KS, Abraham L, Pachigar K, Ludlow R, Khani SC, Smith WC
Mol Vis 2010;16:916-934 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy

Gene therapy for leber’s congential amaurosis is safe and effective through 1.5 years after vector administration

Simonelli F, Maguire AM, Testa F, Pierce EA, Mingozzi F, Bennicelli JL, Rossi S, Marshall K, Banfi S, Surace EM, Sun J, Redmond TM, Zhu X, Shindler KS, Ying GS, Ziviello C, Acerra C, Wright JF, McDonnell JW, High KA, Bennett J, Auricchio A
Mol Ther 2010;18(3):643-650 (Univ. of Pennsylvania – Unres. Grant, Sr. Scientific Inv. Awd and Career Development Awd) Keyword(s): Gene Research/Therapy

A mutation in canine PPT1 causes early onset neuronal ceroid lipofuscinosis in a dachshund

Sanders DN, Farias FH, Johnson GS, Chiang V, Cook JR, O’Brien DP, Hofmann SL, Lu JY, Katz ML
Mol Genetics Metab 2010;100(4):349-356 (Univ. of Missouri – Unres. Grant) Keyword(s): Retina/Retinal Diseases, Gene Research/Therapy

Voltage-gated Na channels in aII amacrine cells accelerate scotopic light responses mediated by the rod bipolar cell pathway

Tian M, Jarsky T, Murphy GJ, Rieke F, Singer JH
J Neurosci 2010;30(13):4650-4659 (Northwestern Univ. – Unres. Grant) Keyword(s): Gene Research/Therapy

Nanodomain control of exocytosis is responsible for the signaling capability of a retinal ribbon synapse

Jarsky T, Tian M, Singer JH
J Neurosci 2010;30(36):11885-11895 (Northwestern Univ. – Unres. Grant) Keyword(s): Gene Research/Therapy

Knockdown of zebrafish lumican gene (zlum) causes scleral thinning and increased size of scleral coats

Yeh LK, Liu CY, Kao WWY, Huang CJ, Hu FR, Chien CL, Wang IJ
J Biol Chem 2010;285(36):28141-28155 (Univ. of Cincinnati – Unres. Grant) Keyword(s): Cornea, Gene Research/Therapy

The use of best visual acuity over several encounters as an outcome variable: An analysis of systematic bias

Koozekanani D, Covert DJ, Weinberg DV
Invest Ophthalmol Vis Sci 2010;51(8):3909-3912 (Medical College of Wisconsin – Unres. Grant) Keyword(s): Other: Clinical Research Methodology

Corneal dystrophies: Molecular genetics to therapeutic intervention--fifth ARVO/Pfizer ophthalmics research institute conference

Weiss JS
Invest Ophthalmol Vis Sci 2010;51(11):5391-5402 (Wayne State Univ. – Unres. Grant) Keyword(s): Cornea, Genetics

Inverse association of female hormone replacement therapy with age-related macular degeneration and interactions with ARMS2 polymorphisms

Edwards DR, Gallins P, Polk M, Ayala-Haedo J, Schwartz SG, Kovach JL, Spencer K, Wang G, Agarwal A, Postel EA, Haines JL, Pericak-Vance M, Scott WK
Invest Ophthalmol Vis Sci 2010;51(4):1873-1879 (Vanderbilt Univ. Medical Center – Unres. Grant) Keyword(s): AMD, Gene Research/Therapy, Genetics

In search of the identity of the XAP-1 antigen: A protein localized to cone outer segments

Nookla S, Gandrakota R, Wohabrebbi A, Wang XF, Howell D, Giorgianni F, Beranova-Giorgianni S, Desiderio DM, Jablonski MM
Invest Ophthalmol Vis Sci 2010;51(5):2736-2743 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): Retina/Retinal Diseases

Retinal cell responses to elevated intraocular pressure: A gene array comparison between the whole retina and retinal ganglion cell layer

Guo Y, Cepurna WO, Dyck JA, Doser TA, Johnson EC, Morrison JC
Invest Ophthalmol Vis Sci 2010;51(6):3003-3018 (Oregon Health & Science Univ. – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Gene Research/Therapy, Glaucoma

Cell transplantation to arrest early changes in an ush2a animal model

Lu B, Wang S, Francis PJ, Li T, Gamm DM, Capowski EE, Lund RD
Invest Ophthalmol Vis Sci 2010;51(4):2269-2276 (Oregon Health & Science Univ. – Unres. Grant and Career Development Awd) Keyword(s): Gene Research/Therapy

Treatment of sheep steroid Induced ocular hypertension with a glucocorticoid-inducible MMP1 gene therapy virus

Gerometta R, Spiga M, Borrás T, Candia OA
Invest Ophthalmol Vis Sci 2010;51(6):3042-3048 (Univ. of North Carolina – Unres. Grant) Keyword(s): Gene Research/Therapy, Glaucoma

Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma

Spiga M, Borrás T
Invest Ophthalmol Vis Sci 2010;51(6):3029-3041 (Univ. of North Carolina – Unres. Grant) Keyword(s): Gene Research/Therapy, Glaucoma

Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys

Buie LK, Rasmussen CA, Porterfield EC, Ramgolam VS, Choi VW, Markovic-Plese S, Samulski RJ, Kaufman PL, Borrás T
Invest Ophthalmol Vis Sci 2010;51(1):236-248 (Univ. of North Carolina – Unres. Grant) Keyword(s): Gene Research/Therapy, Glaucoma

Treatment of sheep steroid-induced ocular hypertension with a glucocorticoid-inducible MMP1 gene therapy virus

Gerometta R, Spiga MG, Borras T, Candia OA
Invest Ophthalmol Vis Sci 2010;51(6):3042-3048 (Mount Sinai School of Medicine, New York - Unres. Grant) Keyword(s): Gene Research/Therapy, Glaucoma

Effect of high versus low oral doses of valacyclovir on herpes simplex virus-1 DNA shedding into tears of latently infected rabbits

Kumar M, Kaufman HE, Clement C, Bhattacharjee PS, Huq T, Varnell ED, Thompson HW, Hill JM
Invest Ophthalmol Vis Sci 2010;51(9):4703-4706 (Louisiana State Univ. Health Sciences Center School of Medicine – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Gene Research/Therapy, Uveitis/Infectious Diseases

Diabetic eNOS-knockout mice develop accelerated retinopathy

Li Q, Verma A, Han PY, Nakagawa T, Johnson RJ, Grant MB, Campbell-Thompson M, Jarajapu YP, Lei B, Hauswirth WW
Invest Ophthalmol Vis Sci 2010;51(10):5240-5246 (Univ. of Florida – Unres. Grant) Keyword(s): Diabetic Retinopathy, Gene Research/Therapy, Retina/Retinal Diseases

Ophthalmic drug delivery systems for the treatment of retinal diseases: Basic research to clinical applications

Edelhauser HF, Rowe-Rendleman CL, Robinson MR, Dawson DG, Chader GJ, Grossniklaus HE, Rittenhouse KD, Wilson CG, Weber DA, Kuppermann BD, Csaky KG, Olsen TW, Kompella UB, Holers VM, Hageman GS, Gilger BC, Campochiaro PA, Whitcup SM, Wong WT
Invest Ophthalmol Vis Sci 2010;51(11):5403-5420 (Emory Univ. Eye Center - Unres. Grant) Keyword(s): AMD, Glaucoma, Macular Dystrophy, Retinal/Retinal Diseases, Other: Ocular Drug Delivery

Monoallelic expression of Krt12 gene during corneal-type epithelium differentiation of limbal stem cells

Hayashi Y, Call MK, Liu CY, Hayashi M, Babcock G, Ohashi Y, Kao WWY
Invest Ophthalmol Vis Sci 2010;51(9):4562-4568 (Univ. of Cincinnati – Unres. Grant) Keyword(s): Cornea, Gene Research/Therapy

Digital versus film fundus photography for research grading of diabetic retinopathy severity

Li HK, Hubbard LD, Danis RP, Esquivel A, Florez-Arango JF, Ferrier NJ, Krupinski EA
Invest Ophthalmol Vis Sci 2010;51(11):5846-5852 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Diabetic Retinopathy

COCH transgene expression in cultured human trabecular meshwork cells and its effect on outflow facility in monkey organ cultured anterior segments

Lee ES, Gabelt BT, Faralli JA, Peters DM, Brandt CR, Kaufman PL, Bhattacharya SK
Invest Ophthalmol Vis Sci 2010;51(4): 2060-2066 (Univ. of Wisconsin – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Gene Research/Therapy, Glaucoma

Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys

Buie LK, Rasmussen CA, Porterfield EC, Ramgolam VS, Choi VW, Markovic-Plese S, Samulski RJ, Kaufman PL, Borras T
Invest Ophthalmol Vis Sci 2010;51(1):236-248 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Gene Research/Therapy, Glaucoma

Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration

Wang G, Spencer KL, Scott WK, Whitehead P, Court BL, Ayala-Haedo J, Mayo P, Schwartz SG, Kovach JL, Gallins P, Polk M, Agarwal A, Postel EA, Haines JL, Pericak-Vance MA
Hum Genet 2010;127(5):595-602 (Vanderbilt Univ. Medical Center – Unres. Grant) Keyword(s): AMD, Gene Research/Therapy, Genetics

Self-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency

Pang J, Boye SE, Lei B, Boye SL, Everhart D, Ryals R, Umino Y, Rohrer B, Alexander J, Li J, Dai X, Li Q, Chang B, Barlow R, Hauswirth WW
Gene Ther 2010;17(7):815-826 (Medical Univ. of South Carolina – Unres. Grant) Keyword(s): Gene Research/Therapy; Other: LCA

Self-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency

Pang J, Boye SE, Lei B, Boye SL, Everhart D, Ryals R, Umino Y, Rohrer B, Alexander J, Li J, Dai X, Li Q, Chang B, Barlow R, Hauswirth WW
Gene Ther 2010;17:815-826 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy, Retina/Retinal Diseases

Oxidative damage of mitochondrial DNA in diabetes and its protection by manganese superoxide dismutase

Madsen-Bouterse SA, Zhong Q, Mohammad G, Ho YS, Kowluru RA
Free Rad Research 2010;44(3):313-321 (Wayne State Univ. – Unres. Grant) Keyword(s): Diabetic Retinopathy

Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa

Cai X, Conley SM, Nash Z, Fliesler SJ, Cooper MJ, Naash MI
FASEB J 2010;24(4):1178-1191 (State Univ. of New York at Buffalo – Unres. Grant) Keyword(s): Gene Research/Therapy, Retina/Retinal Diseases, Retinitis Pigmentosa

Variations in the rheostat model of apoptosis: What studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins

Nickells RW
Exp Eye Res 2010;91(1):2-8 (Univ. of Wisconsin – Unres. Grant and Lew R. Wasserman Merit Awd) Keyword(s): Gene Research/Therapy, Glaucoma

AAV serotype influences gene transfer in corneal stroma in vivo

Sharma A, Tovey JCK, Ghosh A, Mohan RR
Exp Eye Res 2010;91(3):440-448 (Univ. of Missouri – Unres. Grant) Keyword(s): Cornea, Gene Research/Therapy

Decorin transfection suppresses profibrogenic genes and myofibroblast formation in human corneal fibroblasts

Mohan RR, Gupta R, Mehan MK, Cowden JW, Sinha S
Exp Eye Res 2010;91(2):238-245 (Univ. of Missouri – Unres. Grant) Keyword(s): Cornea, Gene Research/Therapy

Gene therapy for the cornea, conjunctiva and lacrimal gland

Sharma A, Ghosh A, Siddappa C, Mohan RR
Encyclopedia Eye 2010;2:185-194 (Univ. of Missouri – Unres. Grant) Keyword(s): Gene Research/Therapy

Confirmation of changes in human meibum lipid infrared spectra with age using principal component analysis

Borchman, D, Foulks GN, Yappert MC
Current Eye Research 2010;35(9):778-786 (Univ. of Louisville – Unres. Grant) Keyword(s): Dry Eye

Castroviejo Lecture 2009: 40 years in search of the perfect contact lens

Cavanagh HD, Robertson DM, Petroll WM, JV Jester
Cornea 2010;29(10):1075-1085 (Univ. of Texas, Southwestern at Dallas – Unres. Grant) Keyword(s): Other: Contact Lens

Castroviejo lecture 2009: 40 years in search of the perfect contact lens

Cavanaugh HD, Robertson DM, Petroll WM, Jester JV
Cornea 2010;29(10):1075-1085 (Univ. of California, Irvine – Challenge Grant) Keyword(s): Cornea, Dry Eye

Induction of corneal myofibroblasts by lens-derived transforming growth factor β1 (TGFβ1): A transgenic mouse model

Reneker LW, Bloch A, Xie L, Overbeek PA, Ash JD
Brain Research Bulletin 2010;81(2-3):287-296 (Univ. of Oklahoma Health Sciences Center – Unres. Grant) Keyword(s): Cornea, Other: Diabetic Complications

Transduction efficiency of AAV 2/6, 2/8 and 2/9 vectors for delivering genes in human corneal fibroblasts

Sharma A, Ghosh A, Hansen ET, Newman JM, Mohan RR
Brain Res Bull 2010;81(2-3):273-278 (Univ. of Missouri – Unres. Grant) Keyword(s): Cornea, Gene Research/Therapy

Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis

Pelzel HR, Schlamp CL, Nickells RW
BMC Neurosci 2010;11:62 (Univ. of Wisconsin – Unres. Grant and Lew R. Wasserman Merit Awd) Keyword(s): Gene Research/Therapy, Glaucoma

The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein

Semaan SJ, Nickells RW
BMC Cancer 2010;10(1):554 (Univ. of Wisconsin – Unres. Grant and Lew R. Wasserman Merit Awd) Keyword(s): Gene Research/Therapy

Feasibility of high-throughput genome-wide genotyping using DNA from stored buccal cell samples

Loomis SJ, Olson LM, Pasquale LR, Wiggs J, Mirel D, Crenshaw A, Parkin M, Rahhal B, Tetreault S, Kraft P, Tworoger SS, Haines JL, Kang JH
Biomark Insights 2010;5:49-55 (Harvard Medical School – Unres. Grant and Physician-Scientist Awd) Keyword(s): Gene Research/Therapy

Induction of rapid and highly efficient expression of the human ND4 complex I subunit in the mouse visual system by self-complementary adeno-associated virus

Koilkonda RD, Chou TH, Porciatti V, Hauswirth WW, Guy J
Arch Ophthalmol 2010;128(7):876-883 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy, Optic Neuropathy

Leber hereditary optic neuropathy gene therapy clinical trial recruitment: Year 1

Lam BL, Feuer WJ, Abukhalil F, Porciatti V, Hauswirth WW, Guy J
Arch Ophthalmol 2010;128(9):1129-1135 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy, Optic Neuropathy

The multicenter uveitis steroid treatment trial: Rationale, design, and baseline characteristics

The Multicenter Uveitis Steroid Treatment Trial Research Group
Am J Ophthalmol 2010;149(4):550-561 (Univ. of Pennsylvania – Unres. Grant and James S. Adams Scholar) Keyword(s): Uveitis/Infectious Diseases

Differential effects of cytokines and corticosteroids on Toll-like receptor 2 expression and activity in human airway epithelia

Winder AA, Wohlford-Lenane C, Scheetz TE, Nardy BN, Manzel LJ, Look DC, McCray Jr PB
Respir Res 2009;10:96 (Univ. of Iowa – Unres. Grant and Career Development Awd) Keyword(s): Gene Research/Therapy, Inflammatory Disease

Curcio CA, Johnson M, Huang JD, Rudolf M
Progress in Retinal & Eye Research 2009;28:393-422 (Univ. of Alabama at Birmingham – Unres. Grant) Keyword(s): Retina/Retinal Diseases

Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells

Cicero SA, Johnson D, Reyntjens S, Frase S, Connell S, Chow LML, Baker SJ, Sorrentino BP, Dyer MA
PNAS 2009;106(16);6685-6690 (Univ. of Tennessee Health Science Center – Unres. Grant and Lew R. Wasserman Merit Awd) Keyword(s): Gene Research/Therapy

Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis

Awano T, Johnson GS, Wade CM, Katz ML, Johnson GC, Taylor JF, Perloski M, Biagi T, Baranowska I, Long S, March PA, Olby NJ, Shelton D, Khan S, O’Brien DP, Lindblad-Toh K, Coates JR
Proc Natl Acad Sci USA 2009;106:2794-2799 (Univ. of Missouri – Unres. Grant) Keyword(s): Gene Research/Therapy

A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles

Cai X, Nash Z, Conley SM, Fliesler SJ, Cooper MJ, Naash MI
PLoS One 2009;4(4):e5290 (State Univ. of New York at Buffalo – Unres. Grant). Keyword(s): Gene Research/Therapy

Autofluorescence and infrared retinal imaging in patients and obligate carriers with neuronal ceroid lipofuscinosis

Kelly J, Rowell G, Weiss A, Seigel GM
Ophthal Genet 2009;30(4):190-198 (State Univ. of New York at Buffalo – Unres. Grant and Sybil Harrington Research Scholar Awd) Keyword(s): Pediatric

Gene therapy for red-green colour blindness in adult primates

Mancuso K, Hauswirth WW, Li Q, Connor TB, Kuchenbecker JA, Mauck MC, Neitz J, Neitz M
Nature 2009;461:784-787 (Medical College of Wisconsin – Unres. Grant) Keyword(s): Gene Research/Therapy

Gene therapy for red-green colour blindness in adult primates

Mancuso K, Hauswirth WW, Li Q, Connor TB, Kuchenbecker JA, Mauck MC, Neitz J, Neitz M
Nature 2009;461:784-787 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy

Adeno-associated virus serotype-0 efficiently transduces the retinal outer plexiform layer

Lei B, Zhang K, Yue Y, Ghosh A, Duan D
Mol Vis 2009;15:1374-1382 (Univ. of Missouri – Unres. Grant) Keyword(s): Gene Research/Therapy

Comparison of non-viral methods to genetically modify and enrich populations of primary human corneal endothelial cells

Engler C, Kelliher C, Wahlin KJ, Speck CL, Jun AS
Mol Vis 2009;15:629-637 (Johns Hopkins Univ. – Unres. Grant and Dolly Green Scholar) Keyword(s): Cornea, Gene Research/Therapy

AAV retinal transduction in a large animal model species: Comparison of a self-complementary AAV2/5 with a single-stranded AAV2/5 vector

Petersen-Jones SM, Bartoe JT, Fischer AJ, Scott M, Boye SL, ChiodoV, Hauswirth WW
Mol Vis 2009;15:1835-1842 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy

Gene therapy following subretinal AAV5 vector delivery is not affected by previous intravitreal AAV5 vector administration in the partner eye

Li W, Kong F, Li X, Dai X, Liu X, Zheng Q, Wu R, Zhou X, Lü F, Chang B, Li Q, Hauswirth WW, Qu J, Pang JJ
Mol Vis 2009;15:267-275 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy

High efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

Petrs-Silva H, Dinculescu A, Li Q, Min S, Chiodo V, Pang JJ, Zhong L, Zolotukhin S, Srivastava A, Lewin AS, Hauswirth WW
Mol Ther 2009;17:463-471 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy

NeuroD regulates proliferation of photoreceptor progenitors in the retina of the zebrafish

Ochocinska M, Hitchcock PF
Mech Dev 2009;126:128-41 (Univ. of Michigan – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina/Retinal Diseases, Gene Research/Therapy

Age-dependent effects of RPE65 gene therapy for Leber’s congenital Amaurosis: a phase 1 dose-escalation trial

Maguire AM, High KA, Auricchio A, Wright JF, Pierce EA, Test F, Mingozzi F, Bennicelli JL, Ying GS, Rossi S, Fulton A, Marshall KA, Banfi S, Chung DC, Morgan JIW, Hauck B, Zelenaia O, Zhu X, Raffini L, Coppieters F, DeBaere E, Shindler KS, Volpe NJ, Surace EM, Acerra C, Lyubarsky A, Redmond TM, Stone E, Sun J, McDonnell JW, Leroy BP, Simonelli F, Bennett J
The Lancet 2009;374:1597-1605 (Univ. of Pennsylvania – Unres. Grant, Sr. Scientific Inv. Awd, Physician-Scientist Awd, Research Sabbatical Grant and Career Development Awd) Keyword(s): Gene Therapy

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: A phase 1 dose-escalation trial

Maguire AM, High KA, Auricchio A, Wright JF, Pierce EA, Testa F, Mingozzi F, Bennicelli JL, Ying G-S, Rossi S, Fulton A, Marshall KA, Banfi S, Chung DC, Morgan JIW, Hauck B, Zelenaia O, Zhu X, Raffini L, Coppieters F, Baere ED, Shindler KS, Volpe NJ, Surace EM, Acerra C, Lyubarsky A, Redmond TM, Stone E, Sun J, McDonnell JW, Leroy BP, Simonelli F, Gauderman JB
Lancet 2009;374:1597-605 (Univ. of Iowa - Unres. Grant) Keyword(s): Gene Research/Therapy

Structural insights into the inhibited states of the Mer receptor tyrosine kinase

Huang X, Finerty Jr P, Walker JR, Butler-Cole C, Vedadi M, Schapira M, Parker SA, Turk BE, Thompson DA, and Dhe-Paganon S
J Struct Biol 2009;165:88-96 (Univ. of Michigan – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Genetics, Gene Research/Therapy

Women's health initiative diet intervention did not increase macular pigment optical density in an ancillary study of a subsample of the women's health initiative

Moeller SM, Voland R, Sarto GE, Gobel VL, Streicher SL, Mares JA
J Nutr 2009;139(9):1692-9 (Univ. of Wisconsin – Unres. Grant and Research Sabbatical Grant) Keyword(s): Macular Pigment

Trafficking of membrane proteins to cone but not rod outer segments is dependent on heterotrimeric kinesin-II

Avasthi P, Watt CB, Williams DS, Le YZ, Li S, Chen CK, Marc RE, Frederick JM, Baehr W
J Neurosci 2009;29(45):14287-14298 (Univ. of Utah - Unres. Grant) Keyword(s): Gene Research/Therapy, Retinitis Pigmentosa

Genetic dissection of rod and cone pathways in the dark-adapted mouse retina

Abd-El-Barr MM, Pennesi ME, Saszik SM, Barrow AJ, Lem J, Bramblett DE, Paul DL, Frishlman LJ, Wu SM
J Neurophysiol 2009;102:1945-1955 (Baylor College of Medicine – Unres. Grant) Keyword(s): Gene Research, Retina/Retinal Diseases

The cellular expression of Midkine-a and -b during retinal development and photoreceptor regeneration

Calinescu AA, Vihtelic T, Hyde D, Hitchcock PF
J Comp Neurol 2009;514:1-10 (Univ. of Michigan – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina/Retinal Diseases, Gene Research/Therapy

Quantitative AP-1 gene regulation by oxidative stress in the human retinal pigment epithelium

Chaum E, Yin J, Yang H, Thomas F, Land JC
J Cell Biochem 2009;108:1280-1291 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): AMD, Gene Research

Loss of NF-κB control and repression of Prdx6 gene transcription by reactive oxygen species-driven SMAD3-mediated transforming growth factor β signaling

Fatma N, Kubo E, Takamura Y, Ishihara K, Garcia C, Beebe DC, Singh DP
J Biol Chem 2009;284:22758-22772 (Univ. of Nebraska – Unres. Grant) Keyword(s): Gene Research/Therapy

RDH12 activity and effects on retinoid processing in the murine retina

Chrispell JD, Feathers K, Kane M, Brooks M, Khanna R, Kurth I, Hübner C, Gal A, Mears A, Swaroop A, Napoli JL, Sparrow JR, Thompson DA
J Biol Chem 2009;284:21468-21477 (Univ. of Michigan – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina/Retinal Diseases, AMD, Gene Research/Therapy

Light Responses in Rods of Vitamin A-Deprived Xenopus

Solessio E, Umino Y, Cameron D, Loew E, Engbretson GA, Knox BE, Barlow RB
Invest Ophthalmol Vis Sci 2009;50:4477-86 (SUNY Upstate Medical Univ. – Unres. Grant) Keyword(s): Gene Research/Therapy

Subretinal transplantation of forebrain progenitor cells in nonhuman primates: survival and intact retinal function

Francis PJ, Wang S, Zhang Y, Brown A, Hwang T, McFarland TJ, Jeffrey BG, Lu B, Wright L, Appukuttan B, Wilson DJ, Stout JT, Neuringer M, Gamm DM, Lund RD
Invest Ophthalmol Vis Sci 2009;50(7):3425-3431 (Oregon Health & Science Univ. – Unres. Grant and Career Development Awd) Keyword(s): Gene Research/Therapy, Retina/Retinal Diseases

Harmonin in the murine retina and the retinal phenotypes of Ush1c-mutant mice and human USH1C

Williams D, Aleman T, Lillo C, Lopes VS, Hughes LC, Stone EM, Jacobson SG
Invest Ophthalmol Vis Sci 2009;50:3881-9 (Univ. of Iowa - Unres. Grant) Keyword(s): Gene Research/Therapy, Retina/Retinal Diseases

Defining the residual vision in Leber congenital amaurosis caused by RPE65 mutations

Jacobson SG, Aleman T, Cideciyan AV, Roman AJ, Sumaroka A, Windsor EA, Schwartz SB, Heon E, Stone EM
Invest Ophthalmol Vis Sci 2009;50:2368-75 (Univ. of Iowa - Unres. Grant) Keyword(s): Gene Research/Therapy

Efficiency and safety of AAV-mediated gene delivery of the human ND4 Complex I subunit in the mouse visual system

Guy J, Qi X, Koilkonda RD, Arguello T, Chou TH, Ruggeri M, Porciatti V, Lewin AS, Hauswirth WW
Invest Ophthalmol Vis Sci 2009;50:4205-4214 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy

Effect of CNTF on retinal ganglion cell survival in experimental glaucoma

Pease ME, Zack DJ, Berlinicke CA, Bloom KM, Cone FE, Wang Y, Klein RL, Hauswirth WW, Quigley HA
Invest Ophthal Vis Sci 2009;50:2194-2200 (Univ. of Florida – Unres. Grant) Keyword(s): Gene Research/Therapy; Optic Neuropathy; Retina/Retinal Diseases; Glaucoma

Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina

Fuhrmann S, Riesenberg A, Mathiesen AM, Brown EC, Vetter ML, Chen S, Brown NL
IOVS 2009;50(1):432-440 (Univ. of Utah – Unres. Grant) Keyword(s): Genetics, Gene Research/Therapy

Heat-induced reactivation of HSV-1 in latently infected mice: Upregulation in the trigeminal ganglia of predominantly CD83 and other immune response genes and their potential role in the viral LAT-ICP0 locus

Clement C, Bhattacharjee PS, Kaufman HE, Hill JM
Invest Ophthalmol Vis Sci 2009;50:2855-2861 (Louisiana State Univ. Health Sciences Center School of Medicine - Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Gene Research/Therapy

Nanoparticles in ophthalmic medicine

Qazi Y, Stagg B, Ambati B
Intl J Nanotech Biol 2009;1:B3-B8 (Univ. of Utah – Unres. Grant and Physician-Scientist Awd) Keyword(s): Gene Research/Therapy

Immunoreactivity of ICAM-1 in human tumors, metastases and normal tissues

Hayes SH, Seigel GM
Int. J Clin Exp Path 2009;2(6):553-560 (State Univ. of New York at Buffalo – Unres. Grant and Sybil Harrington Research Scholar Awd) Keyword(s): Retinoblastoma

Predicting the pathogenicity of RPE65 mutations

Philpa AR, Jin M, Li S, Schindler EI, Iannaccone A, Lam BL, Weleber RG, Fishman GA, Jacobson SG, Mullins RF, Travis GH, Stone EM
Human Mutation 2009;30(8)1183-1188 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): Gene Research/Therapy, Genetics, Retinitis Pigmentosa

ABCA4 disease progression and a proposed strategy for gene therapy

Cideciyan AV, Swider M, Aleman TS, Tsybovsky Y, Schwartz SB, Windsor EAM, Roman AJ, Sumaroka A, Steinberg JD, Jacobson SG, Stone EM, Palczewski K
Hum Mol Genet 2009;18:931-41 (Univ. of Iowa - Unres. Grant) Keyword(s): Gene Research/Therapy

Developing SDOCT to Assess Donor Human Eyes Prior to Tissue Sectioning for Research

Brown N, Koreishi A, McCall M, Izatt J, Bowes Rickman C, Toth CA
Graefes Arch Clin Exp Ophthal 2009;247(8):1069-80 (Duke Univ. – Unres. Grant and Wm & Mary Greve Scholar) Keyword(s): AMD

Diabetic macular edema: a growing global problem, in search of a leaner and clearer vision for the future

Lauer AK, Dhoot D
Expert Reviews of Ophthalmology 2009;4(3):215-218 (Oregon Health & Science Univ. – Unres. Grant) Keyword(s): Retina/Retinal Diseases

Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse

Rex TS, Wong Y, Kodali K, Merry S
Exp Eye Res 2009;89:735-740 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): Retina/Retinal Diseases, Gene Research/Therapy

Age-related changes in the meibomian gland

Nien CJ, Paugh JR, Massei S, Wahlert AJ, Kao WW, Jester JV
Exp Eye Res 2009;89(6):1021-7 (Univ. of Cincinnati College of Medicine – Unres. Grant) Keyword(s): Genetics, Gene Research/Therapy, Imaging, Dry Eye

Electrically assisted delivery of macromolecules into the corneal epithelium

Hao J, Li SK, Liu CY, Kao WW
Exp Eye Res 2009;89(6):934-41 (Univ. of Cincinnati College of Medicine – Unres. Grant) Keyword(s): Cornea, Gene Research/Therapy

Development of lead hammerhead ribozyme candidates against human rod opsin for retinal degeneration therapy

Abdelmaksoud H, Yau EH, Zuker M, Sullivan JM
Exp Eye Res 2009;88(5):859-879 (State Univ. of New York at Buffalo – Unres. Grant) Keyword(s): Gene Research/Therapy

A human apolipoprotein E mimetic peptide effectively inhibits HSV-1 TK-positive and TK-negative acute epithelial keratitis in rabbits

Bhattacharjee PS, Neumann DM, Hill JM
Curr Eye Res 2009;34:99-102 (Louisiana State Univ. Health Sciences Center School of Medicine- Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Gene Research/Therapy

Autofluorescence Imaging and Phenotypic variance in a Sibling pair with Early Onset Retinal Dystrophy due to defective CRB1 function

Tosi J, Tsui I, Lima L, Wang NK, Tsang SH
Curr Eye Res 2009;34:395-400 (Columbia Univ. – Unres. Grant) Keyword(s): Gene Research/Therapy

Clinical and research applications of anterior segment optical coherence tomography - a review

Ramos JL, Li Y, Huang D
Clin Experiment Ophthalmol 2009;37:81-89 (Univ. of Southern California – Unres. Grant) Keyword(s): Imaging

Association between dietary fat intake and age-related macular degeneration in the carotenoids in age-related eye disease study (CAREDS): an ancillary study of the women's health initiative

Parekh N, Voland RP, Moeller SM, Blodi BA, Ritenbaugh C, Chappell RJ, Wallace RB, Mares JA; CAREDS Research Study Group
Arch Ophthalmol 2009;127(11):1483-93 (Univ. of Wisconsin – Unres. Grant and Research Sabbatical Grant) Keyword(s): AMD

Treatment of adult-onset acute macular retinoschisis in enhanced S-cone syndrome with oral acetazolamide

Iannaccone A, Fung KH, Eyestone ME, Stone EM
Am J Ophthalmol 2009;147(2)307-312.e2 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): Gene Research/Therapy, Macular Dystrophy, Retinitis Pigmentosa, Imaging

Relation of response to treatment with dorzolamide in X-linked retinoschisis to the mechanism of functional loss in retinoschisin

Walia S, Fishman GA, Molday RS, Dyka FM, Kumar NM, Ehlinger MA, Stone EM
Am J Ophthalmol 2009;147:111-5 (Univ. of Iowa - Unres. Grant) Keyword(s): Gene Research/Therapy, Retina/Retinal Diseases

Light regulation of Ca2+ in the cone photoreceptor synaptic terminal

Choi SY, Jackman S, Thoreson WB, Kramer RH
Vis Neurosci 2008;25:693-700 (Univ. of Nebraska – Unres. Grant and Research Sabbatical Grant) Keyword(s): Cone, Photoreceptor

Barriers for retinal gene therapy: separating fact from fiction

Kumar-Singh R
Vision Research 2008; 48:1671-1680 (Tufts Univ. - Challenge Grant) Keyword(s): Gene Therapy

Derivation of neurons with functional properties from adult limbal epithelium: implications in autologous cell therapy for photoreceptor degeneration

Zhao X, Das AV, Bhattacharya S, Thoreson WB, Rodriguez Sierra J, Mallya K, Ahmad I
Stem Cells 2008;26:939-949 (Univ. of Nebraska – Unres. Grant and Research Sabbatical Grant) Keyword(s): Stem Cells, Retina

Rat models for glaucoma research

Morrison JC, Johnson E, Cepurna WO
Prog Brain Res 2008;173:285-301 (Oregon Health & Science Univ. – Unres. Grant) Keyword(s): Glaucoma

Retinal precursors and the development of geographic atrophy in age-related macular degeneration

Klein ML, Ferris FL 3rd, Armstrong J, Hwang TS, Chew EY, Bressler SB, Chandra SR; AREDS Research Group
Ophthalmology 2008;115(6):1026-31 (Univ. of Wisconsin – Unres. Grant) Keyword(s): AMD

MultiPriDe: automated batch development of quantitative real-time PCR primers

Ziesel AC, Chrenek MA, Wong PW
Nucleic Acids Research 2008;36;9:3095-3100 (Emory Univ. Eye Center - Unres. Grant) Keyword(s): AMD

NEIBank: Genomics and bioinformatics resources for vision research

Wistow G, Peterson K, Gao J, Buchoff P, Jaworski C, Bowes Rickman C, Ebright JN, Hauser MA, Hoover D
Mol Vision 2008;14:1327-1337 (Duke Univ. School of Medicine - Unres. Grant and Wm. and Mary Greve Scholar) Keyword(s): AMD

Diabetes regulates small molecular weight G-protein, H-Ras, in the microvasculature of the retina: Implication in the development of retinopathy

Kanwar M, Kowluru RA
Microvascular Research 2008;76:189-193 (Wayne State Univ. – Unres. Grant) Keyword(s): Diabetic Retinopathy

7-Ketocholesterol activates caspases-3/7, -8, and -12 in human microvascular endothelial cells in vitro

Luthra S, Dong J, Gramajo A, Chwa M, Kim D, Neekhra A, Kuppermann B, Kenney M
Microvascular Research 2008;75:343-350 (Univ. of California Irvine – Challenge Grant) Keyword(s): AMD

In-vivo xenograft urine human uveal melanoma model develops hepatic micrometastases

Yang H, Fang G, Huang X, Yu J, Hsieh C, Grossniklaus Hans
Melanoma Research 2008;18:95-103 (Emory Univ. Eye Center - Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Ocular Melanoma

Depletion of calcium stores regulates calcium influx and signal transmission in rod photoreceptors

Szikra T, Cusato K, Thoreson WB, Barabas P, Bartoletti TM, Krizaj D
J Physiol 2008;586:4859-4875 (Univ. of Nebraska – Unres. Grant and Research Sabbatical Grant) Keyword(s): Retina, Photoreceptors

Drug delivery to posterior intraocular tissues: Third Annual ARVO/Pfizer Ophthalmics Research Institute Conference

Edelhauser HF, Boatright JH, Nickerson JM, The Third ARVO/Pfizer Research Institute Working Group
Invest Ophthalmol Vis Sci. 2008;11;49:4712-4720 (Emory Univ. Eye Center - Unres. Grant) Keyword(s): Drug Delivery

Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search

Garvin MK, Abramoff MD, Kardon R, Russell SR, Wu X, Sonka M
IEEE Trans Med Imaging 2008;27:1495-505 (Univ. of Iowa - Unres. Grant) Keyword(s): AMD

Mechanisms involved in A2E oxidation

Kim SR, Jockusch S, Itagaki Y, Turro NJ, Sparrow JR
Exp Eye Research 2008;86:975-982 (Columbia Univ. – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Macular Dystrophy

Low-density lipoprotein has an enormous capacity to bind (E)-4-hydroxynon-2-enal (HNE):detection and characterization of lysyl and histidyl adducts containing multiple molecules of HNE

Annangudi SP, Deng Y, Gu X, Zhang W, Crabb JW, Salomon RG
Chemical Research in Toxicology. 2008;21(7):1384-95 (Cleveland Clinic Lerner College of Medicine – Challenge Grant and Sr. Scientific Inv. Awd) Keyword(s): AMD

Vision function in HIV-infected individuals without retinitis. Report of the Studies of Ocular Complications of AIDS Research Group

Freeman WR, Van Natta ML, Jabs DA, Sample PA, Sadun AA, Thorne J, Shah KH, Holland GN for the SOCA Research Group
Am J Ophthalmol 2008;145:453-462 (Baylor College of Medicine – Unres. Grant) Keyword(s): Low Vision

Two mouse retinal degenerations caused by missense mutations in the β-subunit of rod cGMP phosphodiesterase gene

Chang B, Hawes NL, Pardue MT, German AM, Hurd RE, Davisson MT, Nusinowitz S, Rengarajan K, Boyd AP, Sidney SS, Phillips MJ, Steward RE, Chaudhury R, Nickerson JN, Heckenlively JR, Boatright JB
Vision Research 2007;47:624-633 (Emory Univ. – Unres. Grant ) Keyword(s): Gene Therapy

The length of Henle fibers in the human retina and a model of ganglion receptive field density in the visual field

Drasdo N, Millican CL, Katholi CR, Curcio CA
Vis Research 2007;47:2901-2911 (Univ. of Alabama – Unres. Grant) Keyword(s): Glaucoma

Crystallins in the eye: function and pathology

Andley UP
Progress in Retina and Eye Research 2007;1:78-98 (Washington Univ. - Unres. Grant) Keyword(s): Cataract

Lipids of human meibum: mass-spectrometric analysis and structural elucidation

Butovich I, Uchiyama E, McCulley J
Journal of Lipid Research 2007;48:2220-2235 (Univ. of Texas, Southwestern - Unres. Grant) Keyword(s): Tear Film Lipid Layer

Knowledge, attitudes, and beliefs about dilated eye examinations among African-Americans

Ellish NJ, Royak-Schaler R, Passmore SR, Higginbotham EJ
Invest Ophthalmol Vis Sci 2007;48:1989-1994 (Univ. of Maryland – Unres. Grant) Keyword(s): Health Services Research, Epidemiology

Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death

Vasireddy V, Uchida Y, Salem N Jr, Kim SY, Mandal MN, Reddy GB, Bodepudi R, Alderson NL, Brown JC, Hama H, Dlugosz A, Elias PM, Holleran WM, Ayyagari R
Hum Mol Genet. 2007;16:471-82 (Univ. of Michigan – Unres. Grant and Int’l Research Scholar) Keyword(s): Macular Dystrophy

Heterotypic RPE cell contact increases choroidal endothelial cell transmigration through PI 3-kinase and rac1

EXPERIMENTAL EYE RESEARCH Peterson LJ, Wittchen E, Geisen P, Burridge K, Hartnett ME
Exp Eye Res 2007;84:737-744 (Univ. of North Carolina – Challenge Grant and Physician-Scientist Award) Keyword(s): AMD

Molecular testing for hereditary retinal disease as part of clinical care

Downs K, Zacks DN, Caruso R, Karoukis AJ, Branham K, Yashar BM, Haimann MH, Trzupek K, Meltzer M, Blain D, Richards JE, Weleber RG, Heckenlively JR, Sieving PA, Ayyagari R
Arch Ophthalmol. 2007;125:252-8 (Univ. of Michigan – Unres. Grant and Int’l Research Scholar) Keyword(s): Retinal Dystrophies

Cone Phototransduction and Growth of the ERG b-wave During Light Adaptation

Alexander KR, Raghuram A, Rajagopalan AS
Vision Research 2006;46:3941-8 (Univ. of Illinois at Chicago – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina and Retinal Disease

Activation Phase of Cone Phototransduction and the Flicker Electroretinogram in Retinitis Pigmentosa

Alexander KR, Rajagopalan AS, Raghuram A, Fishman GA
Vision Research 2006;46:2773-85 (Univ. of Illinois at Chicago – Unres. Grant) Keyword(s): Retinitis Pigmentosa

Contrast Sensitivity for Letter Optotypes Vs

McAnany JJ, Alexander KR
Gratings under Conditions Biased Toward Parvocellular and Magnocellular Pathways. Vision Research 2006;46:1574-84 (Univ. of Illinois at Chicago – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina and Retinal Disease

Cortical Visual Function in the rd12 Mouse Model of Leber Congenital Amarousis (LCA) after Gene Replacement Therapy to Restore Retinal Function

Nusinowitz S, Ridder WH III, Pang JJ, Chang B, Noorwez SM, Kaushal S, Hauswirth WW, Heckenlively JR
Vision Research 2006;46:3926-3934 (Univ. of California, Los Angeles – Unres. Grant) Keyword(s): Retina, Gene Replacement Therapy

Impact Of Aging And Age-Related Maculopathy On Inactivation Of The A-Wave Of The Rod-Mediated Electroretinogram

Jackson GR, McGwin G Jr, Phillips JM, Klein R, Owsley
Vision Research 2006;46:1422-1431 (Univ. of Alabama at Birmingham – Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): AMD

Studies of Ocular Complications of AIDS Research Group: Causes of Visual Acuity Loss Among Patients with AIDS and Cytomegalovirus Retinitis in the Era of Highly Active Antiretroviral Therapy

Thorne JE, Jabs DA, Kempen JH, Holbrook JT, Nichols C, Meinert CL
Ophthalmology 2006;113:1441-1445 (Johns Hopkins Univ. - Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina and Retinal Diseases

Studies of Ocular Complications of AIDS Research Group

Thorne JE, Jabs DA, Kempen JH, Holbrook JT, Nichols C, Meinert CL
Incidence of and Risk Factors for Visual Acuity Loss among Patients with AIDS and Cytomegalovirus Retinitis in the Era of Highly Active Antiretroviral Therapy. Ophthalmology 2006;113:1432-1440 (Johns Hopkins Univ. -Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina and Retinal Diseases

Risk of Immune Recovery Uveitis in Patients with AIDS and Cytomegalovirus Retinitis

Kempen JH, Min YI, Freeman WR, Holland GN, Friedberg DN, Dieterich DT, Jabs DA Studies of Ocular Complications of AIDS Research Group
Ophthalmology 2006;113:684-694 (Johns Hopkins Univ. – Unres. Grant, Sr. Scientific Inv. Awd and UCLA-Physician-Scientist Awd) Keyword(s): Uveitis

Risk of Immune Recovery Uveitis in Patients with AIDS and Cytomegalovirus Retinitis

Kempen JH, Min YI, Freeman WR, Holland GN, Friedberg DN, Dieterich DT, Jabs DA; Studies of Ocular Complications of AIDS Research Group
Ophthalmology 2006;113(4):684-694 (Univ. of California, Los Angeles – Unres. Grant and Physician-Scientist Awd) Keyword(s): Uveitis, AIDS

Trends of Penetrating Keratoplasty in the United States from 1980 to 2004

Darlington JK, Adrean SD, Schwab IR
Ophthalmology 2006;113:2171-2175 (Univ. of California, Davis – Unres. Grant and Research Sabbatical Grant) Keyword(s): Cornea Transplants, Cornea

Enhanced Proangiogenic Signaling In Thrombospondin-1-Deficient Retinal Endothelial Cells

Wang Y, Wang S, Sheibani N
Microvascular Research 2006;71:143-151 (Univ. of Wisconsin – Unres. Grant and Career Development Awd) Keyword(s): Retinal Vasculature

Synthesis And Characterization Of A Novel Class Of Reducing Agents That Are Highly Neuroprotective For Retinal Ganglion Cells

Schlieve CR, Tam A, Nilsson BL, Lieven CJ, Raines RT, Levin LA
Experimental Eye Research 2006;82:1252-1259 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Optic Neuropathy

Monkey Organ-Cultured Anterior Segments: Technique And Response To H-7

Hu Y, Gabelt BT, Kaufman PL
Experimental Eye Research 2006;82:1100-1108 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Outflow Facility

Choroidal Innervation And Optic Neuropathy In Macacque Monkeys With Laser- Or Anterior Chamber Perfusion-Induced Short Term Elevation Of Intraocular Pressure

May CA, Kaufman PL, Lütjen-Drecoll E, Scholz M
Experimental Eye Research 2006;82:1060-1067 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Optic Neuropathy, Glaucoma

Androgen Receptor And Nfkb Expression In Human Normal And Glaucomatous Optic Nerve Head Astrocytes In Vitro And In Experimental Glaucoma

Agapova OA, Kaufman PL, Hernandez MR
Experimental Eye Research 2006;82:1053-1059 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Glaucoma

Caldesmon Effects On The Actin Cytoskeleton And Cell Adhesion In Cultured HTM Cells

Grosheva I, Vittitow JL, Goichberg P, Gabelt BT, Kaufman PL, Borrás T, Geiger B, Bershadsky AD
Experimental Eye Research 2006;82:945-958 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Gene Therapy

Caldesmon Transgene Expression Disrupts Focal Adhesions In HTM Cells And Increases Outflow Facility In Organ-Cultured Human And Monkey Anterior Segments

Gabelt BT, Hu Y, Vittitow JL, Rasmussen CR, Grosheva I, Bershadsky AD, Geiger B, Borrás T, Kaufman PL
Experimental Eye Research 2006;82:935-944 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Gene Therapy

Latrunculin B Effects On Trabecular Meshwork And Corneal Endothelial Morphology In Monkeys

Sabanay I, Tian B, Gabelt BT, Geiger B, Kaufman PL
Experimental Eye Research 2006;82:236-246 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Cornea

Thymosin B4 Inhibits Benzalkonium Chloride-Mediate Apoptosis in Corneal and Conjunctival Epithelial Cells In Vitro

Sosne G, Albeiruti A-R, Hollis B, Siddiqi A, Ellenberg D, Kurpakus-Wheater M
Experimental Eye Research 2006;83:502-507 (Wayne State Univ. – Unres. Grant and Career Development Awd) Keyword(s): Cornea

Predictability and Limitations of Non-Invasive Murine Tonometry: Comparison of Two Devices

Filippopoulos T, Matsubara A, Danias J, Huang W, Dobberfuhl A, Ren L, Mittag T, Miller JW, Grosskreutz CL
Experimental Eye Research 2006;83:194-201 (Harvard Medical School – Unres. Grant and Career Development Awd) Keyword(s): Glaucoma

Quantitative Assessment Of Local Collagen Matrix Remodeling In 3-D Culture: The Role Of Rho Kinase

Kim A, Lakshman N, Petroll WM
Experimental Cell Research 2006;312:3683-3692 (Univ. of Texas Southwestern - Unres. Grant and Lew R. Wasserman Merit Awd) Keyword(s): Cornea and Wound Healing

Effect of H-7 and Lat-B on Retinal Physiology

Kiland Jam, Miller CL, Kim CBY, Ver Hoeve JN, Gabelt BT, Peterson J, Nork TM, Kaufman PL
Current Eye Research 2006;31:441-445 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Retinal Vascular Permeability

Characterization Of Barrier Properties And Inducible Vegf Expression Of Several Types Of Retinal Pigment Epithelium In Medium-Term Culture

Geisen P, McColm JR, King B, Hartnett ME
Current Eye Research 2006;31(9):739-48 (Univ. of North Carolina – Challenge Grant and Physician-Scientist Awd) Keyword(s): Retina and Retinal Diseases

A Method for Chorioretinal Oxygen Tension Measurement

Shahidi M, Shakoor A, Blair NP, Mori M, Shonat RD
Current Eye Research 2006;31:357-66 (Univ. of Illinois at Chicago - Unres. Grant) Keyword(s): Retinal Vein & Artery Occlusion

Development and Validation of a Computerized Expert System for Evaluation of Automated Visual Fields from the Ischemic Optic Neuropathy Decompression Trial

Feldon SE, Levin L, Scherer RW, Arnold A, Chung SM, Johnson LN, Kosmorsky G, Newman SA, Katz J, Langenberg P, Wilson PD, Kelman SE, Dickersin K and members of the Ischemic Optic Neuropathy Decompression Trial Research Group
BMC Ophthal 2006;6:34 (Saint Louis Univ. – Challenge Grant) Keyword(s): Neuro-Ophthalmology, Optic Neuropathy

Associations Between Intermediate Age-Related Macular Degeneration and Lutein and Zeaxanthin in the Carotenoids in Age- Related Eye Disease Study (CAREDS)

Moeller SM, Parekh N, Tinker L, Rittenbaugh C, Blodi B, Wallace RB, Mares JA, Careds Research Study Group
Arch Ophthalmol 2006;124(8):1151-1162 (Univ. of Wisconsin – Unres. Grant) Keyword(s): AMD

HIPAA AND Research: How Have the First Two Years Gone?

Friedman DS
Am J Ophthalmol 2006;141:543-546 (Johns Hopkins Univ. – Unres. Grant and Robert E. McCormick Scholar) Keyword(s): Federal Legislation, Clinical Research

Contrast Sensitivity and Color Vision in HIV-Infected Individuals without Infectious Retinopathy

Shah KH, Holland GN, Yu F, Van Natta M, Nusinowitz S; Studies of Ocular Complications of AIDS (SOCA) Research Group
Am J Ophthalmol 2006;142(2):284-292 (Univ. of California, Los Angeles – Unres. Grant and Physician-Scientist Awd) Keyword(s): Uveitis, AIDS

Research Criteria for the Diagnosis of Birdshot Chorioretinopathy: Results of an International Consensus Conference

Levinson RD, Brezin A, Rothova A, Accorinti M, Holland GN
Am J Ophthalmol 2006;141(1):185-187 (Univ. of California, Los Angeles – Unres. Grant and Physician-Scientist Awd) Keyword(s): Uveitis, Retina

The Watercolor Effect: Quantitative Evidence for Luminance-Dependent Mechanisms of Long-Range Color Assimilation

Devinck F, Delahunt PB, Hardy JL, Spillmann L, Werner JS
Vision Research 2005;45:1413-1424 (Univ. of California, Davis – Unres. Grant and Jules & Doris Stein RPB Prof.) Keyword(s): Other - Color Vision

Imaging Maculopathy in Post-Mortem Human Eyes

Curcio C
Vision Research 2005;5:3496-3503 (Univ. of Alabama - Unres. Grant and Lew R. Wasserman Merit Awd.) Keyword(s): Ageing, Degeneration, Drusen, Electron Microscopy, Fundoscopy, Histochemistry, Maculopathy

Risk Factors for Mortality in Patients with AIDS in the Era of Highly Active Antiretroviral Therapy

Jabs DA, Holbrook JT, Van Natta ML, Clark R, Jacobson MA, Kempen JH, Murphy RL, for the Studies of Ocular Complications of AIDS Research Group
Ophthalmology 2005;112:771-779 (Johns Hopkins Univ. – Unres. Grant and Sr. Scientific Inv. Awd.) Keyword(s): AIDS, Retina and Retinal Diseases

Clinician Versus Reading Center Assessment of Cytomegalovirus Retinitis Lesion Size

Weinberg DV, Holbrook JT, Hubbard LD, Davis MD, Jabs DA, Holland GN, for the Studies of Ocular Complications of AIDS Research Group
Ophthalmology 2005;112:559-566 (Johns Hopkins Univ., Northwestern Univ., Univ. of Wisconsin and Univ. of California, Los Angeles – Unres. Grants and Sr. Scientific Inv. Awd.) Keyword(s): Retina and Retinal Diseases

Risk Factors for Mortality in Patients with AIDS in the Era of Highly Active Antiretroviral Therapy

Jabs DA, Holbrook JT, Van Natta ML, Clark R, Jacobson MA, Kempen JH, Murphy RL, for the Studies of Ocular Complications of AIDS Research Group
Ophthalmology 2005;112:771-779 (Baylor College of Medicine and Johns Hopkins Univ. – Unres. Grants and Sr. Scientific Inv. Awd.) Keyword(s): Retina and Retinal Diseases

The Search for the Retinoblastoma Cell of Origin

Dyer MA, Bremner R
Nature Rev 2005;5:91-101 (Univ. of Tennessee – Unres. Grant) Keyword(s): Other: Gene Expression

Simultaneous Contribution of Two Rod Pathways to AII Amacrine and Cone Bipolar Cell Light Responses

Trexler E, Li W, Massey S
J Neurophysiol 2005;93:1476–1485 (Univ. of Texas, Houston – Unres. Grant and Research Sabbatical Grant) Keyword(s): Retina

Chronically Elevated Glucose-Induced Apoptosis is Mediated by Inactivation of Akt in Cultured Müller Cells

Xi X, Gao L, Hatala DA, Smith DG, Codispoti MC, Gong B, Kern TS, Zhang J
Biochemical and Biophysical Research Communications 2005; 326:548-553. (Case Western Reserve Univ. – Unres. Grant) Keyword(s): Akt; Elevated glucose; Apoptosis; Müller cell; Diabetic retinopathy

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