Research Database

Hawthorne F, Feng S, Metlapally R, Li YJ, Tran-Viet KN, Guggenheim JA, Malecaze F, Calvas P, Rosenberg T, Mackey DA, Venturini C, Hysi PG, Hammond CJ, Young TL

Invest Ophthalmol Vis Sci. 2013 Mar 21;54(3):2076-86

Duke University - Lew R. Wasserman Merit Award

Keywords: Gene Research/Therapy, Myopia/Presbyopia

CYP1B1, MYOC, and LTBP2 mutations in primary congenital glaucoma patients in the united states.

Lim SH, Tran-Viet KN, Yanovitch TL, Freedman SF, Klemm T, Call W, Powell C, Ravichandran A, Metlapally R, Nading EB, Rozen S, Young TL

Am J Ophthalmol. 2013 Mar;155(3):508-17.e5

Duke University - Lew R. Wasserman Merit Award

Keywords: Epidemiology, Gene Research/Therapy, Glaucoma, Other: Exome Sequencing

Dorsomedial/Perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradient.

Samuels BC, Hammes NM, Johnson PL, Shekhar A, McKinnon SJ, Allingham RR

Invest Ophthalmol Vis Sci. 2012 Oct 23;53(11):7328-35

Duke University - Departmental Grant

Keywords: Glaucoma, Other: Intraocular Pressure

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.

Lu Y, Vitart V, Burdon KP, Khor CC, Bykhovskaya Y, Mirshahi A, Hewitt AW, Koehn D, Hysi PG, Ramdas WD, Zeller T, Vithana EN, Cornes BK, Tay WT, Tai ES, Cheng CY, Liu J, Foo JN, Saw SM, Thorleifsson G, Stefansson K, Dimasi DP, Mills RA, Mountain J, Ang W, Hoehn R, Verhoeven VJ, Grus F, Wolfs R, Castagne R, Lackner KJ, Springelkamp H, Yang J, Jonasson F, Leung DY, Chen LJ, Tham CC, Rudan I, Vatavuk Z, Hayward C, Gibson J, Cree AJ, MacLeod A, Ennis S, Polasek O, Campbell H, Wilson JF, Viswanathan AC, Fleck B, Li X, Siscovick D, Taylor KD, Rotter JI, Yazar S, Ulmer M, Li J, Yaspan BL, Ozel AB, Richards JE, Moroi SE, Haines JL, Kang JH, Pasquale LR, Allingham RR, Ashley-Koch A, NEIGHBOR Consortium, Mitchell P, Wang JJ, Wright AF, Pennell C, Spector TD, Young TL, Klaver CC, Martin NG, Montgomery GW, Anderson MG, Aung T, Willoughby CE, Wiggs JL, Pang CP, Thorsteinsdottir U, Lotery AJ, Hammond CJ, van Duijn CM, Hauser MA, Rabinowitz YS, Pfeiffer N, Mackey DA, Craig JE, Macgregor S, Wong TY

Nat Genet. 2013 Feb;45(2):155-63

Duke University - Lew R. Wasserman Merit Award

Keywords: Cornea, Other: Collagen, Other: Mutation, Other: Syndrome

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.

Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Hohn R, MacGregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, Kemp JP, Pourcain BS, Simpson CL, Makela KM, Lehtimaki T, Kahonen M, Paterson AD, Hosseini SM, Wong HS, Xu L, Jonas JB, Parssinen O, Wedenoja J, Yip SP, Ho DW, Pang CP, Chen LJ, Burdon KP, Craig JE, Klein BE, Klein R, Haller T, Metspalu A, Khor CC, Tai ES, Aung T, Vithana E, Tay WT, Barathi VA, Consortium for Refractive Error and Myopia (CREAM), Chen P, Li R, Liao J, Zheng Y, Ong RT, Doring A, Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Evans DM, Timpson NJ, Verkerk AJ, Meitinger T, Raitakari O, Hawthorne F, Spector TD, Karssen LC, Pirastu M, Murgia F, Ang W, Wellcome Trust Case Control Consortium 2 (WTCCC2), Mishra A, Montgomery GW, Pennell CE, Cumberland PM, Cotlarciuc I, Mitchell P, Wang JJ, Schache M, Janmahasatian S, Igo RP,Jr, Lass JH, Chew E, Iyengar SK, Fuchs' Genetics Multi-Center Study Group, Gorgels TG, Rudan I, Hayward C, Wright AF, Polasek O, Vatavuk Z, Wilson JF, Fleck B, Zeller T, Mirshahi A, Muller C, Uitterlinden AG, Rivadeneira F, Vingerling JR, Hofman A, Oostra BA, Amin N, Bergen AA, Teo YY, Rahi JS, Vitart V, Williams C, Baird PN, Wong TY, Oexle K, Pfeiffer N, Mackey DA, Young TL, van Duijn CM, Saw SM, Bailey-Wilson JE, Stambolian D, Klaver CC, Hammond CJ

Nat Genet. 2013 Mar;45(3):314-8

Duke University - Lew R. Wasserman Merit Award

Keywords: Gene Research/Therapy, Myopia/Presbyopia

Mutation in collagen II alpha 1 isoforms delineates stickler and wagner syndrome phenotypes.

Tran-Viet KN, Soler V, Quiette V, Powell C, Yanovitch T, Metlapally R, Luo X, Katsanis N, Nading E, Young TL

Mol Vis. 2013 Apr 5;19:759-66

Duke University - Lew R. Wasserman Merit Award

Keywords: Gene Research/Therapy, Other: Stickler Syndrome, Other: Wagner Syndrome

Mutations in SCO2 are associated with autosomal-dominant high-grade myopia.

Tran-Viet KN, Powell C, Barathi VA, Klemm T, Maurer-Stroh S, Limviphuvadh V, Soler V, Ho C, Yanovitch T, Schneider G, Li YJ, Nading E, Metlapally R, Saw SM, Goh L, Rozen S, Young TL

Am J Hum Genet. 2013 May 2;92(5):820-6

Duke University - Lew R. Wasserman Merit Award

Keywords: Gene Research/Therapy, Myopia/Presbyopia

Pediatric cataract, myopic astigmatism, familial exudative vitreoretinopathy and primary open-angle glaucoma co-segregating in a family.

Mackey DA, Hewitt AW, Ruddle JB, Vote B, Buttery RG, Toomes C, Metlapally R, Li YJ, Tran-Viet KN, Malecaze F, Calvas P, Rosenberg T, Guggenheim JA, Young TL

Mol Vis. 2011;17:2118-28

Duke University - Departmental Grant

Keywords: Cataracts, Genetics, Glaucoma

Refinement of the X-linked nonsyndromic high-grade myopia locus MYP1 on Xq28 and exclusion of 13 known positional candidate genes by direct sequencing.

Ratnamala U, Lyle R, Rawal R, Singh R, Vishnupriya S, Himabindu P, Rao V, Aggarwal S, Paluru P, Bartoloni L, Young TL, Paoloni-Giacobino A, Morris MA, Nath SK, Antonarakis SE, Radhakrishna U

Invest Ophthalmol Vis Sci. 2011 Aug 29;52(9):6814-9

Duke University - Departmental Grant

Keyword: Genetics

Retinal nerve fiber layer reflectance for early glaucoma diagnosis.

Liu S, Wang B, Yin B, Milner TE, Markey MK, McKinnon SJ, Rylander HG,3rd

J Glaucoma. 2014 Jan;23(1):e45-52

Duke University - Lew R. Wasserman Merit Award

Keywords: Glaucoma, Other: Optical Coherence Tomography, Other: Retinal Nerve Fiber Layer

Whole exome sequencing identifies a mutation for a novel form of corneal intraepithelial dyskeratosis.

Soler VJ, Tran-Viet KN, Galiacy SD, Limviphuvadh V, Klemm TP, St Germain E, Fournie PR, Guillaud C, Maurer-Stroh S, Hawthorne F, Suarez C, Kantelip B, Afshari NA, Creveaux I, Luo X, Meng W, Calvas P, Cassagne M, Arne JL, Rozen SG, Malecaze F, Young TL

J Med Genet. 2013 Apr;50(4):246-54

Duke University - Lew R. Wasserman Merit Award

Keywords: Cornea, Gene Research/Therapy, Other: Corneal Intraepithelial Dyskeratosis

Atypical idiopathic intracranial hypertension: Normal BMI and older patients.

Bruce BB, Kedar S, Van Stavern GP, Corbett JJ, Newman NJ, Biousse V

Neurology 2010;74:1827-1832

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Blood pressure threshold for abnormal ocular fundus findings is lower than expected.

Bruce BB, Lamirel C, Wright DW, Biousse V, Newman NJ

Hypertension. 2012 Feb;59(2):e8-9

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Cat scratch disease.

Fraser CL, Sanchez S, Newman NJ, Biousse V

Ophthalmology. 2012 Jul;119(7):1502-3; author reply1503

Emory University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

Exacerbation of susac syndrome retinopathy by interferon beta-1a.

Laird PW, Newman NJ, Yeh S

Arch Ophthalmol. 2012 Jun;130(6):804-6

Emory University - Departmental Grant

Keyword: Retinal Vein and Artery Occlusion

Feasibility of nonmydriatic ocular fundus photography in the emergency department: Phase I of the FOTO-ED study.

Bruce BB, Lamirel C, Biousse V, Ward A, Heilpern KL, Newman NJ, Wright DW

Acad Emerg Med. 2011 Sep;18(9):928-33

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Functional visual loss.

Beau BB, Newman NJ

Neurol Clin 2010;28:789-802

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Genetic screening for OPA1 and OPA3 mutations in patients with suspected inherited optic neuropathies.

Yu-Wai-Man P, Shankar SP, Biousse V, Miller NR, Bean LJ, Coffee B, Hegde M, Newman NJ

Ophthalmology. 2011 Mar;118(3):558-63

Emory University - Departmental Grant

Keywords: Genetics, Optic Neuropathy

Hypertension-related eye abnormalities and the risk of stroke.

Henderson AD, Bruce BB, Newman NJ, Biousse V

Rev Neurol Dis. 2011;8(1-2):1-9

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Leber hereditary optic neuropathy: Some new observations.

Newman NJ

J Neuroophthalmol. 2011 Mar;31(1):3-5

Emory University - Departmental Grant

Keyword: Optic Neuropathy

Meningoceles in idiopathic intracranial hypertension.

Bialer OY, Rueda MP, Bruce BB, Newman NJ, Biousse V, Saindane AM

AJR Am J Roentgenol. 2014 Mar;202(3):608-13

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Minocycline-induced fulminant intracranial hypertension.

Fraser CL, Biousse V, Newman NJ

Arch Neurol. 2012 Aug;69(8):1067-70

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Nonmydriatic digital ocular fundus photography on the iPhone 3G: The FOTO-ED study.

Lamirel C, Bruce BB, Wright DW, Newman NJ, Biousse V

Arch Ophthalmol. 2012 Jul 1;130(7):939-40

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Optic nerve head drusen in black patients.

Thurtell MJ, Biousse V, Bruce BB, Newman NJ

J Neuroophthalmol. 2012 Mar;32(1):13-6

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Quality of nonmydriatic digital fundus photography obtained by nurse practitioners in the emergency department: The FOTO-ED study.

Lamirel C, Bruce BB, Wright DW, Delaney KP, Newman NJ, Biousse V

Ophthalmology. 2012 Mar;119(3):617-24

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Retinal function and structure in Ant1-deficient mice.

Phillips MJ, Webb-Wood S, Faulkner AE, Jabbar SB, Biousse V, Newman NJ, Do VT, Boatright JH, Wallace DC, Pardue MT

Invest Ophthalmol Vis Sci 2010;51(12):6744-6752

Emory University - Departmental Grant

Keywords: Genetics, Neuro-Ophthalmology, Retina/Retinal Diseases

Risk factors for idiopathic intracranial hypertension in men: A case-control study.

Fraser JA, Bruce BB, Rucker J, Fraser LA, Atkins EJ, Newman NJ, Biousse V

J Neurol Sci 2010;290:86-89

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Rod-cone dystrophy in spinocerebellar ataxia type 1.

Thurtell MJ, Biousse V, Newman NJ

Arch Ophthalmol. 2011 Jul;129(7):956-8

Emory University - Departmental Grant

Keywords: Neuro-Ophthalmology, Retina/Retinal Diseases

The 12th hoyt lecture: Neuro-ophthalmology in review: Around the brain with 50 fellows.

Newman NJ

J Neuroophthalmol. 2014 Jun;34(2):206-7

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

The berlin questionnaire screens for obstructive sleep apnea in idiopathic intracranial hypertension.

Thurtell MJ, Bruce BB, Rye DB, Newman NJ, Biousse V

J Neuroophthalmol. 2011 Dec;31(4):316-9

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

The neuro-ophthalmology of mitochondrial disease.

Fraser JA, Biousse V, Newman NJ

Surv Ophthalmol 2010;55(4):299-334

Emory University - Departmental Grant

Keywords: Neuro-Ophthalmology, Optic Neuropathy

The use of retinal photography in nonophthalmic settings and its potential for neurology.

Perez MA, Bruce BB, Newman NJ, Biousse V

Neurologist. 2012 Nov;18(6):350-5

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Transverse sinus stenosis in adult patients with chiari malformation type I.

Saindane AM, Bruce BB, Desai NK, Roller LA, Newman NJ, Biousse V

AJR Am J Roentgenol. 2014 Oct;203(4):890-6

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Treatment of hereditary optic neuropathies.

Newman NJ

Nat Rev Neurol. 2012 Oct;8(10):545-56

Emory University - Departmental Grant

Keyword: Optic Neuropathy

Treatment of leber hereditary optic neuropathy.

Newman NJ

Brain. 2011 Sep;134(Pt 9):2447-50

Emory University - Departmental Grant

Keyword: Optic Neuropathy

Treatment of nonarteritic anterior Ischemic optic neuropathy.

Atkins EJ, Bruce BB, Newman NJ, Biousse V

Surv Ophthalmol 2010;55(1):47-63

Emory University - Departmental Grant

Keywords: Optic Neuropathy, Retinal Vein and Artery Occlusion

Underdiagnosis of posterior communicating artery aneurysm in noninvasive brain vascular studies.

Elmalem VI, Hudgins PA, Bruce BB, Newman NJ, Biousse V

J Neuroophthalmol. 2011 Jun;31(2):103-9

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Update on idiopathic intracranial hypertension.

Bruce BB, Biousse V, Newman NJ

Am J Ophthalmol. 2011 Aug;152(2):163-9

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Update on the pathophysiology and management of idiopathic intracranial hypertension.

Biousse V, Bruce BB, Newman NJ

J Neurol Neurosurg Psychiatry. 2012 May;83(5):488-94

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Updates in neuro-ophthalmology: highlights from the 37th annual meeting of the north american neuro-ophthalmology society,february 5-10, 2011, vancouver, canada.

Szewka AJ, Toffoli D, Newman NJ, Biousse V

Rev Neurol Dis. 2011;8(1-2):48-51

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Vascular neuro-ophthalmology.

Lamirel C, Newman NJ, Biousse V

Neurol Clin 2010;28:701-727

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Visual loss without papilledema in idiopathic intracranial hypertension.

Thurtell MJ, Newman NJ, Biousse V

J Neuro-Ophthalmol 2010;30:94-103

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Visual outcomes after treatment of pituitary adenomas.

Fraser CL, Biousse V, Newman NJ

Neurosurg Clin N Am. 2012 Oct;23(4):607-19

Emory University - Departmental Grant

Keyword: Neuro-Ophthalmology

Blockade of prolymphangiogenic vascular endothelial growth factor C in dry eye disease.

Goyal S, Chauhan SK, Dana R

Arch Ophthalmol. 2012 Jan;130(1):84-9

Harvard Medical School - Lew R. Wasserman Merit Award

Keyword: Dry Eye

Calpain activation in experimental glaucoma.

Huang W, Fileta J, Rawe I, Qu J, Grosskreutz CL

Invest Ophthalmol Vis Sci 2010;51(6):3049-3054

Harvard Medical School - Departmental Grant

Keyword: Glaucoma

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.

Wiggs JL, Yaspan BL, Hauser MA, Kang JH, Allingham RR, Olson LM, Abdrabou W, Fan BJ, Wang DY, Brodeur W, Budenz DL, Caprioli J, Crenshaw A, Crooks K, Delbono E, Doheny KF, Friedman DS, Gaasterland D, Gaasterland T, Laurie C, Lee RK, Lichter PR, Loomis S, Liu Y, Medeiros FA, McCarty C, Mirel D, Moroi SE, Musch DC, Realini A, Rozsa FW, Schuman JS, Scott K, Singh K, Stein JD, Trager EH, Vanveldhuisen P, Vollrath D, Wollstein G, Yoneyama S, Zhang K, Weinreb RN, Ernst J, Kellis M, Masuda T, Zack D, Richards JE, Pericak-Vance M, Pasquale LR, Haines JL

PLoS Genet. 2012;8(4):e1002654

Harvard Medical School - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia.

Ulmer M, Li J, Yaspan BL, Ozel AB, Richards JE, Moroi SE, Hawthorne F, Budenz DL, Friedman DS, Gaasterland D, Haines J, Kang JH, Lee R, Lichter P, Liu Y, Pasquale LR, Pericak-Vance M, Realini A, Schuman JS, Singh K, Vollrath D, Weinreb R, Wollstein G, Zack DJ, Zhang K, Young T, Allingham RR, Wiggs JL, Ashley-Koch A, Hauser MA

Invest Ophthalmol Vis Sci. 2012 Jul 3;53(8):4468-74

Harvard Medical School - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Coverage of vitamin A capsule programme in Bangladesh and risk factors associated with non-receipt of vitamin A.

Semba RD, de Pee S, Sun K, Akhter N, Bloem MW, Raju VK

J Health Popul Nutr 2010;28(2):143-148

Johns Hopkins University - Lew R. Wasserman Merit Award

Keywords: Pediatric, Other: Nutrition

Determinants of anemia clustering among mothers and children in indonesia.

Souganidis ES, Sun K, de Pee S, Kraemer K, Rah JH, Moench-Pfanner R, Sari M, Bloem MW, Semba RD

J Trop Pediatr. 2012 Jun;58(3):170-7

Johns Hopkins University - Lew R. Wasserman Merit Award

Keywords: Epidemiology, Other: Anemia

Household rice expenditure and maternal and child nutritional status in Bangladesh.

Campbell AA, de Pee S, Sun K, Kraemer K, Thorne-Lyman A, Moench-Pfanner R, Sari M, Akhter N, Bloem MW, Semba RD

J Nutr 2010;140(1):189S-194S

Johns Hopkins University - Lew R. Wasserman Merit Award

Keywords: Pediatric, Other: Nutrition

Iron-fortified milk and noodle consumption is associated with lower risk of anemia among children aged 6-59 mo in Indonesia.

Semba RD, Moench-Pfanner R, Sun K, de Pee S, Akhter N, Rah JH, Campbell AA, Badham J, Bloem MW, Kraemer K

Am J Clin Nutr 2010;92(1):170-176

Johns Hopkins University - Lew R. Wasserman Merit Award

Keywords: Pediatric, Other: Nutrition

Low intake of vitamin A-rich foods among children, aged 12-35 months, in India: Association with malnutrition, anemia, and missed child survival interventions.

Semba RD, de Pee S, Sun K, Campbell AA, Bloem MW, Raju VK

Nutrition 2010;26(10):958-962

Johns Hopkins University - Lew R. Wasserman Merit Award

Keywords: Pediatric, Other: Nutrition

Relationship of homestead food production with night blindness among children below 5 years of age in bangladesh.

Campbell AA, Akhter N, Sun K, de Pee S, Kraemer K, Moench-Pfanner R, Rah JH, Badham J, Bloem MW, Semba RD

Public Health Nutr. 2011 Sep;14(9):1627-31

Johns Hopkins University - Lew R. Wasserman Merit Award

Keywords: Other: Home Gardening, Other: Vitamin A, Other: Xerophthalmia

The historical evolution of thought regarding multiple micronutrient nutrition.

Semba RD

J Nutr. 2012 Jan;142(1):143S-56S

Johns Hopkins University - Lew R. Wasserman Merit Award

Keywords: Other: Micronutrients, Other: Nutrition

The role of expanded coverage of the national vitamin A program in preventing morbidity and mortality among preschool children in India.

Semba RD, de Pee S, Sun K, Bloem MW, Raju VK

J Nutr 2010;140(1):208S-212S

Johns Hopkins University - Lew R. Wasserman Merit Award

Keywords: Pediatric, Nutrition

Anatomic changes in Schlemm's canal and collector channels in normal and primary open-angle glaucoma eyes using low and high perfusion pressures.

Hann CR, Vercnocke AJ, Bentley MD, Jorgensen SM, Fautsch MP

Invest Ophthalmol Vis Sci. 2014 Sep;55(9):5834-41

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keyword: Glaucoma

Aqueous humor rapidly stimulates myocilin secretion from human trabecular meshwork cells.

Resch ZT, Hann CR, Cook KA, Fautsch MP

Exp Eye Res 2010;91:901-908

Mayo Medical School - Departmental Grant Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD

Keyword: Glaucoma

ATP-sensitive potassium (KATP) channel activation decreases intraocular pressure in the anterior chamber of the eye.

Chowdhury UR, Bahler CK, Hann CR, Chang M, Resch ZT, Romero MF, Fautsch MP

Invest Ophthalmol Vis Sci. 2011 Aug 16;52(9):6435-42

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keyword: Glaucoma

Body mass index has a linear relationship with cerebrospinal fluid pressure.

Berdahl JP, Fleischman D, Zaydlarova J, Stinnett S, Allingham RR, Fautsch MP

Invest Ophthalmol Vis Sci. 2012 Mar 15;53(3):1422-7

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keyword: Glaucoma

Cerebrospinal fluid pressure decreases with older age.

Fleischman D, Berdahl JP, Zaydlarova J, Stinnett S, Fautsch MP, Allingham RR

PLoS One. 2012;7(12):e52664

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keyword: Glaucoma

Effects of prostaglandin analogues on aqueous humor outflow pathways.

Winkler NS, Fautsch MP

J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):102-9

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keyword: Glaucoma

Expression profile of the matricellular protein osteopontin in primary open-angle glaucoma and the normal human eye.

Chowdhury UR, Jea SY, Oh DJ, Rhee DJ, Fautsch MP

Invest Ophthalmol Vis Sci. 2011 Aug 16;52(9):6443-51

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keyword: Glaucoma

Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT).

Hann CR, Bentley MD, Vercnocke A, Ritman EL, Fautsch MP

Exp Eye Res. 2011 Feb;92(2):104-11

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keywords: Glaucoma, Imaging

Second-generation trabecular meshwork bypass stent (iStent inject) increases outflow facility in cultured human anterior segments.

Bahler CK, Hann CR, Fjield T, Haffner D, Heitzmann H, Fautsch MP

Am J Ophthalmol. 2012 Jun;153(6):1206-13

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keyword: Glaucoma

The elastin fiber system between and adjacent to collector channels in the human juxtacanalicular tissue.

Hann CR, Fautsch MP

Invest Ophthalmol Vis Sci. 2011 Jan 5;52(1):45-50

Mayo Medical School - Lew R. Wasserman Merit Award - Fautsch, Michael P / PhD Departmental Grant

Keyword: Glaucoma

Carbonic anhydrase-related protein VIII is expressed in rod bipolar cells and alters signaling at the rod bipolar to AII-amacrine cell synapse in the mammalian retina.

Puthussery T, Gayet-Primo J, Taylor WR

Eur J Neurosci. 2011 Nov;34(9):1419-31

Oregon Health & Science University - Lew R. Wasserman Merit Award - Taylor, W. Rowland / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Direction selectivity in the retina: Symmetry and asymmetry in structure and function.

Vaney DI, Sivyer B, Taylor WR

Nat Rev Neurosci. 2012 Feb 8;13(3):194-208

Oregon Health & Science University - Lew R. Wasserman Merit Award - Taylor, W. Rowland / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Immunohistochemical identification and synaptic inputs to the diffuse bipolar cell type DB1 in macaque retina.

Puthussery T, Gayet-Primo J, Taylor WR, Haverkamp S

J Comp Neurol. 2011 Dec 15;519(18):3640-56

Oregon Health & Science University - Lew R. Wasserman Merit Award - Taylor, W. Rowland / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Inhibitory mechanisms that generate centre and surround properties in ON and OFF brisk-sustained ganglion cells in the rabbit retina.

Buldyrev I, Taylor WR

J Physiol. 2013 Jan 1;591(Pt 1):303-25

Oregon Health & Science University - Lew R. Wasserman Merit Award - Taylor, W. Rowland / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina.

Puthussery T, Venkataramani S, Gayet-Primo J, Smith RG, Taylor WR

J Neurosci. 2013 Oct 9;33(41):16045-59

Oregon Health & Science University - Lew R. Wasserman Merit Award - Taylor, W. Rowland / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Synaptic pathways that shape the excitatory drive in an OFF retinal ganglion cell.

Buldyrev I, Puthussery T, Taylor WR

J Neurophysiol. 2012 Apr;107(7):1795-807

Oregon Health & Science University - Lew R. Wasserman Merit Award - Taylor, W. Rowland / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

The role of starburst amacrine cells in visual signal processing.

Taylor WR, Smith RG

Vis Neurosci. 2012 Jan;29(1):73-81

Oregon Health & Science University - Lew R. Wasserman Merit Award - Taylor, W. Rowland / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Complement factor H genetic variant and age-related macular degeneration: Effect size, modifiers and relationship to disease subtype.

Sofat R, Casas JP, Webster AR, Bird AC, Mann SS, Yates JR, Moore AT, Sepp T, Cipriani V, Bunce C, Khan JC, Shahid H, Swaroop A, Abecasis G, Branham KE, Zareparsi S, Bergen AA, Klaver CC, Baas DC, Zhang K, Chen Y, Gibbs D, Weber BH, Keilhauer CN, Fritsche LG, Lotery A, Cree AJ, Griffiths HL, Bhattacharya SS, Chen LL, Jenkins SA, Peto T, Lathrop M, Leveillard T, Gorin MB, Weeks DE, Ortube MC, Ferrell RE, Jakobsdottir J, Conley YP, Rahu M, Seland JH, Soubrane G, Topouzis F, Vioque J, Tomazzoli L, Young I, Whittaker J, Chakravarthy U, de Jong PT, Smeeth L, Fletcher A, Hingorani AD

Int J Epidemiol. 2012 Feb;41(1):250-62

University of California, Los Angeles - Lew R. Wasserman Merit Award Senior Scientific Investigator Award

Keywords: AMD, Gene Research/Therapy

Deep intronic mutation in OFD1, identified by targeted genomic next-generation sequencing, causes a severe form of X-linked retinitis pigmentosa (RP23).

Webb TR, Parfitt DA, Gardner JC, Martinez A, Bevilacqua D, Davidson AE, Zito I, Thiselton DL, Ressa JH, Apergi M, Schwarz N, Kanuga N, Michaelides M, Cheetham ME, Gorin MB, Hardcastle AJ

Hum Mol Genet. 2012 Aug 15;21(16):3647-54

University of California, Los Angeles - Lew R. Wasserman Merit Award Senior Scientific Investigator Award

Keywords: Gene Research/Therapy, Retina/Retinal Diseases, Retinitis Pigmentosa

Genetic insights into age-related macular degeneration: Controversies addressing risk, causality, and therapeutics.

Gorin MB

Mol Aspects Med. 2012 Aug;33(4):467-86

University of California, Los Angeles - Lew R. Wasserman Merit Award Senior Scientific Investigator Award

Keywords: AMD, Gene Research/Therapy

Intrinsically photosensitive retinal ganglion cells are the primary but not exclusive circuit for light aversion.

Matynia A, Parikh S, Chen B, Kim P, McNeill DS, Nusinowitz S, Evans C, Gorin MB

Exp Eye Res. 2012 Dec;105:60-9

University of California, Los Angeles - Lew R. Wasserman Merit Award Senior Scientific Investigator Award

Keywords: Neuro-Ophthalmology, Other: Light Aversion, Other: Ocular Pain

Molecular diagnosis of putative stargardt disease probands by exome sequencing.

Strom SP, Gao YQ, Martinez A, Ortube C, Chen Z, Nelson SF, Nusinowitz S, Farber DB, Gorin MB

BMC Med Genet. 2012 Aug 3;13:67

University of California, Los Angeles - Lew R. Wasserman Merit Award Senior Scientific Investigator Award

Keywords: Gene Research/Therapy, Retina/Retinal Diseases

A watertight acrylic-free titanium recording chamber for electrophysiology in behaving monkeys.

Adams DL, Economides JR, Jocson CM, Parker JM, Horton JC

J Neurophysiol. 2011 Sep;106(3):1581-90

University of California, San Francisco - Disney Award for Amblyopia Research - Horton, Jonathan C / MD, PhD Departmental Grant

Keyword: Neuro-Ophthalmology

Clinical signs in dematiaceous and hyaline fungal keratitis.

Oldenburg CE, Prajna VN, Prajna L, Krishnan T, Mascarenhas J, Vaitilingam CM, Srinivasan M, See CW, Cevallos V, Zegans ME, Acharya NR, Lietman TM

Br J Ophthalmol. 2011 May; 95(5):750-1

University of California, San Francisco - Departmental Grant

Keyword: Cornea

Orientation tuning of cytochrome oxidase patches in macaque primary visual cortex.

Economides JR, SincichLC, Adams DL, Horton JC

Nat Neurosci. 2011 Nov 6;14(12):1574-80

University of California, San Francisco - Disney Award for Amblyopia Research - Horton, Jonathan C / MD, PhD Departmental Grant

Keyword: Neuro-Ophthalmology

Topical fluoroquinolone use as a risk factor for in vitro fluoroquinolone resistance in ocular cultures.

Fintelmann R, Hoskins E, Lietman T, Keenan J, Gaynor B, Cevallos V, Acharya NR

Arch Ophthalmol. 2011 Apr;129(4):399-402

University of California, San Francisco - Career Development Award - Keenan, Jeremy / MD, MPH Departmental Grant

Keyword: Uveitis/Infectious Diseases

Interaction of arrestin with enolase1 in photoreceptors.

Smith WC, Bolch S, Dugger DR, Li J, Esquenazi I, Arendt A, Benzenhafer D, McDowell JH

Invest Ophthalmol Vis Sci. 2011 Mar 29;52(3):1832-40

University of Florida - Lew R. Wasserman Merit Award - Smith, W. Clay / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

A role for heparan sulfate in viral surfing.

Oh MJ, Akhtar J, Desai P, Shukla D

Biochem Biophys Res Commun 2010;391:176-181

University of Illinois - Lew R. Wasserman Merit Award

Keyword: Cornea

Corneal latency and transmission of herpes simplex virus-1.

Farooq AV, Shukla D

Future Virol. 2011 Jan;6(1):101-8

University of Illinois - Lew R. Wasserman Merit Award Medical Student Eye Research Fellowship

Keyword: Other: Herpes Simplex Virus

Early events in herpes simplex virus lifecycle with implications for an infection of lifetime.

Salameh S, Sheth U, Shukla D

Open Virol J. 2012;6:1-6

University of Illinois - Lew R. Wasserman Merit Award

Keywords: Cornea, Other: Herpes Simplex Virus

Herpes simplex epithelial and stromal keratitis: An epidemiologic update.

Farooq AV, Shukla D

Surv Ophthalmol. 2012 Sep;57(5):448-62

University of Illinois - Lew R. Wasserman Merit Award Medical Student Eye Research Fellowship

Keywords: Cornea, Other: Herpes Simplex Virus

In vitro antiviral activity of neem (Azardirachta indica L.) bark extract against herpes simplex virus type-1infection.

Tiwari V, Darmani NA, Yue BY, Shukla D

Phytother Res 2010;24:1132-1140

University of Illinois - Lew R. Wasserman Merit Award

Keyword: Cornea

Nonprofessional phagocytosis can facilitate herpesvirus entry into ocular cells.

Tiwari V, Shukla D

Clin Dev Immunol. 2012;2012:651691

University of Illinois - Lew R. Wasserman Merit Award

Keywords: Cornea, Other: Herpes Simplex Virus

A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel loci.

Scheetz TE, Fingert JH, Wang K, Kuehn MH, Knudtson KL, Alward WL, Boldt HC, Russell SR, Folk JC, Casavant TL, Braun TA, Clark AF, Stone EM, Sheffield VC

PLoS One. 2013;8(3):e58657

University of Iowa - Career Development Award Lew R. Wasserman Merit Award

Keywords: AMD, Gene Research/Therapy, Glaucoma

Chromatic pupillometry in patients with retinitis pigmentosa.

Kardon R, Anderson SC, Damarjian TG, Grace EM, Stone E, Kawasaki A

Ophthalmology. 2011 Feb;118(2):376-81

University of Iowa - Departmental Grant

Keywords: Neuro-Ophthalmology, Retinitis Pigmentosa

Copy number variations and primary open-angle glaucoma.

Davis LK, Meyer KJ, Schindler EI, Beck JS, Rudd DS, Grundstad AJ, Scheetz TE, Braun TA, Fingert JH, Alward WL, Kwon YH, Folk JC, Russell SR, Wassink TH, Sheffield VC, Stone EM

Invest Ophthalmol Vis Sci. 2011 Sep 9;52(10):7122-33

University of Iowa - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Genome-wide analysis of copy number variants in age-related macular degeneration.

Meyer KJ, Davis LK, Schindler EI, Beck JS, Rudd DS, Grundstad AJ, Scheetz TE, Braun TA, Fingert JH, Alward WL, Kwon YH, Folk JC, Russell SR, Wassink TH, Stone EM, Sheffield VC

Hum Genet. 2011 Jan;129(1):91-100

University of Iowa - Departmental Grant

Keywords: AMD, Gene Research/Therapy

Pupillographic Investigation of the relative afferent pupillary defect associated with a midbrain lesion.

Kawasaki A, Miller NR, Kardon R

Ophthalmology 2010;117(1):175-179

University of Iowa - Departmental Grant

Keyword: Neuro-Ophthalmology

Quantitative trait loci associated with murine central corneal thickness.

Lively GD, Koehn D, Hedberg-Buenz A, Wang K, Anderson MG

Physiol Genomics 2010;42(2):281-286

University of Iowa - Lew R. Wasserman Merit Award

Keywords: Cornea, Genetics

Anti-CD3 antibody ameliorates experimental autoimmune uveitis by inducing both IL-10 and TGF-beta dependent regulatory T cells.

Ke Y, Jiang G, Sun D, Kaplan HJ, Shao H

Clin Immunol. 2011 Mar;138(3):311-20

University of Louisville - Lew R. Wasserman Merit Award - Shao, Hui / MD, PhD Departmental Grant

Keyword: Uveitis/Infectious Diseases

Exosomes from retinal astrocytes contain antiangiogenic components that inhibit laser-induced choroidal neovascularization.

Hajrasouliha AR, Jiang G, Lu Q, Lu H, Kaplan HJ, Zhang HG, Shao H

J Biol Chem. 2013 Sep 27;288(39):28058-67

University of Louisville - Lew R. Wasserman Merit Award - Shao, Hui / MD, PhD Departmental Grant

Keyword: Retina/Retinal Diseases

HMGB1 is an early and critical mediator in an animal model of uveitis induced by IRBP-specific T cells.

Jiang G, Sun D, Yang H, Lu Q, Kaplan HJ, Shao H

J Leukoc Biol. 2014 Apr;95(4):599-607.

University of Louisville - Lew R. Wasserman Merit Award - Shao, Hui / MD, PhD Departmental Grant

Keywords: Uveitis/Infectious Diseases, Other: autoimmune disease, Other: autoreactive T cells, Other: damage-associated molecular patterns, Other: immunoregulation, Other: pathogen recognition receptors

IL-22-induced regulatory CD11b+ APCs suppress experimental autoimmune uveitis.

Ke Y, Sun D, Jiang G, Kaplan HJ, Shao H

J Immunol. 2011 Sep 1;187(5):2130-9

University of Louisville - Lew R. Wasserman Merit Award - Shao, Hui / MD, PhD Departmental Grant

Keyword: Uveitis/Infectious Diseases

Activation of P2X receptors induces apoptosis in human retinal pigment epithelium.

Yang D, Elner SG, Clark AJ, Hughes BA, Petty HR, Elner VM

Invest Ophthalmol Vis Sci. 2011 Mar 18;52(3):1522-30

University of Michigan - Lew R. Wasserman Merit Award

Keyword: Retina/Retinal Diseases

Advances in the management of thyroid eye disease.

Briceno CA, Gupta S, Douglas RS

Int Ophthalmol Clin. 2013 Summer;53(3):93-101

University of Michigan - Lew R. Wasserman Merit Award - Douglas, Raymond S / MD, PhD

Keyword: Thyroid Ophthalmology

Can topical ketorolac 0.5% improve the function of ahmed(R) glaucoma drainage devices?

Scott GR, Weizer JS, Moroi SE, Bruno CA, Musch DC, Niziol LM, Lee PP, Stein JD

Ophthalmic Surg Lasers Imaging. 2011 May-Jun;42(3):190-5

University of Michigan - Departmental Grant

Keyword: Glaucoma

Characterization of the R162W Kir7.1 mutation associated with snowflake vitreoretinopathy.

Zhang W, Zhang X, Wang H, Sharma AK, Edwards AO, Hughes BA

Am J Physiol Cell Physiol. 2013 Mar 1;304(5):C440-9

University of Michigan - Lew R. Wasserman Merit Award

Keyword: Retina/Retinal Diseases

Clinical characteristics of newly diagnosed primary, pigmentary and pseudoexfoliative open-angle glaucoma in the collaborative initial glaucoma treatment study.

Musch DC, Shimizu T, Niziol LM, Gillespie BW, Cashwell LF, Lichter PR

Br J Ophthalmol. 2012 Sep;96(9):1180-4

University of Michigan - Departmental Grant

Keyword: Glaucoma

Clinical phenotypes and prognostic full-field electroretinographic findings in stargardt disease.

Zahid S, Jayasundera T, Rhoades W, Branham K, Khan N, Niziol LM, Musch DC, Heckenlively JR

Am J Ophthalmol. 2013 Mar;155(3):465-73.e3

University of Michigan - Lew R. Wasserman Merit Award

Keyword: Retina/Retinal Diseases

Diabetes and nonrefractive visual impairment: The young have it.

Musch DC, Gardner TW

JAMA. 2012 Dec 12;308(22):2403-4

University of Michigan - Physician-Scientist Award - Gardner, Thomas W / MD, MS Departmental Grant

Keyword: Diabetic Retinopathy

Effect of gestational age and birth weight on the risk of strabismus among premature infants.

Gulati S, Andrews CA, Apkarian AO, Musch DC, Lee PP, Stein JD

JAMA Pediatr. 2014 Sep;168(9):850-6

University of Michigan - Physician-Scientist Award - Stein, Joshua D / MD, MS

Keywords: Strabismus/Amblyopia/Eye Movement Disorders, Epidemiology, Other: Health Services Research

Effects of KCNQ channel modulators on the M-type potassium current in primate retinal pigment epithelium.

Pattnaik BR, Hughes BA

Am J Physiol Cell Physiol. 2012 Mar 1;302(5):C821-33

University of Michigan - Lew R. Wasserman Merit Award

Keyword: Retina/Retinal Diseases

Identification of persons with incident ocular diseases using health care claims databases.

Stein JD, Blachley TS, Musch DC

Am J Ophthalmol. 2013 Dec;156(6):1169-75.e3

University of Michigan - Physician-Scientist Award - Stein, Joshua D / MD, MS

Keyword: Other: Health Services Research

Incidence of, risk factors for, and combined mechanism of late-onset open-angle glaucoma after vitrectomy.

Koreen L, Yoshida N, Escariao P, Niziol LM, Koreen IV, Musch DC, Chang S

Retina. 2012 Jan;32(1):160-7

University of Michigan - Departmental Grant

Keyword: Glaucoma

Increased expression of TSH receptor by fibrocytes in thyroid-associated ophthalmopathy leads to chemokine production.

Gillespie EF, Papageorgiou KI, Fernando R, Raychaudhuri N, Cockerham KP, Charara LK, Goncalves AC, Zhao SX, Ginter A, Lu Y, Smith TJ, Douglas RS

J Clin Endocrinol Metab. 2012 May;97(5):E740-6

University of Michigan - Lew R. Wasserman Merit Award - Douglas, Raymond S / MD, PhD Departmental Grant

Keyword: Thyroid Ophthalmology

Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: Involvement of akt and NF-kappaB.

Gillespie EF, Raychaudhuri N, Papageorgiou KI, Atkins SJ, Lu Y, Charara LK, Mester T, Smith TJ, Douglas RS

Invest Ophthalmol Vis Sci. 2012 Nov 21;53(12):7746-53

University of Michigan - Lew R. Wasserman Merit Award - Douglas, Raymond S / MD, PhD Departmental Grant

Keyword: Thyroid Ophthalmology

KCNQ5/K(v)7.5 potassium channel expression and subcellular localization in primate retinal pigment epithelium and neural retina.

Zhang X, Yang D, Hughes BA

Am J Physiol Cell Physiol. 2011 Nov;301(5):C1017-26

University of Michigan - Lew R. Wasserman Merit Award

Keyword: Retina/Retinal Diseases

Long-term outcomes in patients who received a corneal graft for keratoconus between 1980 and 1986.

Niziol LM, Musch DC, Gillespie BW, Marcotte LM, Sugar A

Am J Ophthalmol. 2013 Feb;155(2):213-9.e3

University of Michigan - Lew R. Wasserman Merit Award

Keyword: Cornea

Multifocal visual evoked potentials for early glaucoma detection.

Weizer JS, Musch DC, Niziol LM, Khan NW

Ophthalmic Surg Lasers Imaging. 2012 Jul 1;43(4):335-40

University of Michigan - Departmental Grant

Keyword: Glaucoma

Rates of nonexudative and exudative age-related macular degeneration among asian american ethnic groups.

Stein JD, Vanderbeek BL, Talwar N, Nan B, Musch DC, Zacks DN

Invest Ophthalmol Vis Sci. 2011 Aug 29;52(9):6842-8

University of Michigan - Departmental Grant

Keywords: AMD, Other: Epidemiology

Reliability of simultaneous visual field testing.

Kramer BC, Musch DC, Niziol LM, Weizer JS

Ophthalmology. 2012 Feb;119(2):304-7

University of Michigan - Departmental Grant

Keyword: Glaucoma

Risk of endophthalmitis and other long-term complications of trabeculectomy in the collaborative initial glaucoma treatment study (CIGTS).

Zahid S, Musch DC, Niziol LM, Lichter PR, Collaborative Initial Glaucoma Treatment Study Group

Am J Ophthalmol. 2013 Apr;155(4):674-80.e1

University of Michigan - Lew R. Wasserman Merit Award

Keyword: Glaucoma

Thyrotropin receptor and CD40 mediate interleukin-8 expression in fibrocytes: implications for thyroid associated ophthalmopathy.

Douglas RS, Mester T, Ginter A, Kim D

Trans Am Ophthalmol Soc. 2014 May;112:26-37

University of Michigan - Lew R. Wasserman Merit Award - Douglas, Raymond S / MD, PhD Departmental Grant

Keyword: Thyroid Ophthalmology

Contribution of mucoviscosity-associated gene A (magA) to virulence in experimental klebsiella pneumoniae endophthalmitis.

Hunt JJ, Wang JT, Callegan MC

Invest Ophthalmol Vis Sci. 2011 Aug 29;52(9):6860-6

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Uveitis/Infectious Diseases

The diabetic ocular environment facilitates the development of endogenous bacterial endophthalmitis.

Coburn PS, Wiskur BJ, Christy E, Callegan MC

Invest Ophthalmol Vis Sci. 2012 Nov 1;53(12):7426-31

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Retina/Retinal Diseases, Uveitis/Infectious Diseases

A robust procedure for distinctively visualizing zebrafish retinal cell nuclei under bright field light microscopy.

Fu J, Fang W, Zou J, Sun M, Lathrop K, Su G, Wei X

J Histochem Cytochem. 2013 Mar;61(3):248-56

University of Pittsburgh - Lew R. Wasserman Merit Award - Wei, Xiangyun / PhD Departmental Grant

Keywords: Gene Research/Therapy, Retina/Retinal Diseases

Characterization of transgenic zebrafish lines that express GFP in the retina, pineal gland, olfactory bulb, hatching gland, and optic tectum.

Fang W, Bonaffini S, Zou J, Wang X, Zhang C, Tsujimura T, Kawamura S, Wei X

Gene Expr Patterns. 2013 Jun-Jul;13(5-6):150-9

University of Pittsburgh - Lew R. Wasserman Merit Award - Wei, Xiangyun / PhD Departmental Grant

Keywords: Gene Research/Therapy, Retina/Retinal Diseases

Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains.

Zou J, Wang X, Wei X

Dev Cell. 2012 Jun 12;22(6):1261-74

University of Pittsburgh - Lew R. Wasserman Merit Award - Wei, Xiangyun / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Spatial-temporal expressions of crumbs and nagie oko and their interdependence in zebrafish central nervous system during early development.

Zou J, Wen Y, Yang X, Wei X

Int J Dev Neurosci. 2013 Dec;31(8):770-82

University of Pittsburgh - Lew R. Wasserman Merit Award - Wei, Xiangyun / PhD Departmental Grant

Keywords: Gene Research/Therapy, Retina/Retinal Diseases

Differential impact of partial cortical blindness on gaze strategies when sitting and walking - an immersive virtual reality study.

Iorizzo DB, Riley ME, Hayhoe M, Huxlin KR

Vision Res. 2011 May 25;51(10):1173-84

University of Rochester - Lew R. Wasserman Merit Award - Huxlin, Krystel R / PhD Departmental Grant

Keywords: Low Vision, Neuro-Ophthalmology

Different properties of visual relearning after damage to early versus higher-level visual cortical areas.

Das A, Demagistris M, Huxlin KR

J Neurosci. 2012 Apr 18;32(16):5414-25

University of Rochester - Lew R. Wasserman Merit Award - Huxlin, Krystel R / PhD Departmental Grant

Keyword: Low Vision

First demonstration of ocular refractive change using blue-IRIS in live cats.

Savage DE, Brooks DR, DeMagistris M, Xu L, MacRae S, Ellis JD, Knox WH, Huxlin KR

Invest Ophthalmol Vis Sci. 2014 Jul;55(7):4603-12.

University of Rochester - Lew R. Wasserman Merit Award - Huxlin, Krystel R / PhD Departmental Grant

Keywords: Cornea, Myopia/Presbyopia

High-resolution, noninvasive, two-photon fluorescence measurement of molecular concentrations in corneal tissue.

Cui L, Huxlin KR, Xu L, MacRae S, Knox WH

Invest Ophthalmol Vis Sci. 2011 Apr 20;52(5):2556-64

University of Rochester - Lew R. Wasserman Merit Award - Huxlin, Krystel R / PhD Departmental Grant

Keywords: Cornea, Imaging

Inhibitory effects of PPARgamma ligands on TGF-beta1-induced corneal myofibroblast transformation.

Jeon KI, Kulkarni A, Woeller CF, Phipps RP, Sime PJ, Hindman HB, Huxlin KR

Am J Pathol. 2014 May;184(5):1429-45.

University of Rochester - Lew R. Wasserman Merit Award - Huxlin, Krystel R / PhD Departmental Grant

Keyword: Cornea

Keratocyte apoptosis and not myofibroblast differentiation mark the graft/host interface at early time-points post-DSAEK in a cat model.

Weis AJ, Huxlin KR, Callan CL, DeMagistris MA, Hindman HB

PLoS One. 2013 Sep 30;8(9):e75623

University of Rochester - Lew R. Wasserman Merit Award - Huxlin, Krystel R / PhD Departmental Grant

Keyword: Cornea

Phantom study of tear film dynamics with optical coherence tomography and maximum-likelihood estimation.

Huang J, Lee KS, Clarkson E, Kupinski M, Maki KL, Ross DS, Aquavella JV, Rolland JP

Opt Lett. 2013 May 15;38(10):1721-3

University of Rochester - Lew R. Wasserman Merit Award

Keyword: Gene Research/Therapy

Topical rosiglitazone is an effective anti-scarring agent in the cornea.

Huxlin KR, Hindman HB, Jeon KI, Buhren J, MacRae S, DeMagistris M, Ciufo D, Sime PJ, Phipps RP

PLoS One. 2013 Aug 5;8(8):e70785

University of Rochester - Lew R. Wasserman Merit Award - Huxlin, Krystel R / PhD

Keyword: Cornea

Serum carboxymethyllysine, an advanced glycation end product, and age-related macular degeneration: The age, gene/environment susceptibility-reykjavik study.

Semba RD, Cotch MF, Gudnason V, Eiriksdottir G, Harris TB, Sun K, Klein R, Jonasson F, Ferrucci L, Schaumberg DA

JAMA Ophthalmol. 2014 Apr;132(4):464-70

University of Utah - Departmental Grant

Keywords: AMD, Epidemiology

A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death.

Semaan SJ, Li Y, Nickells RW

ASN Neuro 2010;2(2):e00032

University of Wisconsin - Departmental Grant Lew R. Wasserman Merit Award

Keywords: Genetics, Glaucoma

Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis.

Pelzel HR, Schlamp CL, Nickells RW

BMC Neurosci 2010;11:62

University of Wisconsin - Departmental Grant Lew R. Wasserman Merit Award

Keywords: Gene Research/Therapy, Glaucoma

The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein.

Semaan SJ, Nickells RW

BMC Cancer 2010;10(1):554

University of Wisconsin - Departmental Grant Lew R. Wasserman Merit Award

Keyword: Gene Research/Therapy

Variations in the rheostat model of apoptosis: What studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins.

Nickells RW

Exp Eye Res 2010;91(1):2-8

University of Wisconsin - Departmental Grant Lew R. Wasserman Merit Award

Keywords: Gene Research/Therapy, Glaucoma

The microbead occlusion model: A paradigm for induced ocular hypertension in rats and mice.

Sappington RM, Carlson BJ, Crish SD, Calkins DJ

Invest Ophthalmol Vis Sci 2010;51(1):207-216

Vanderbilt University - Departmental Grant Career Development Award - Sappington, Rebecca M / PhD

Keywords: Glaucoma, Optic Neuropathy

Active opsin loci adopt intrachromosomal loops that depend on the photoreceptor transcriptionfactor network.

Peng G-H, Chen S

Proc Natl Acad Sci U S A. 2011;108:17821-6

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

A role for epha2 in cell migration and refractive organization of the ocular lens.

Shi Y, De Maria A, Bennett T, Shiels A, Bassnett S

Invest Ophthalmol Vis Sci. 2012 Feb 1;53(2):551-9

Washington University - Departmental Grant

Keyword: Cataract

Biological glass: Structural determinants of eye lens transparency.

Bassnett S, Shi Y, Vrensen GF

Philos Trans R Soc Lond B Biol Sci. 2011;366:1250-64

Washington University - Departmental Grant

Keyword: Cataract

Cadm1 expression and function in the mouse lens.

De Maria AB, Shi Y, Luo X, Van Der Weyden L, Bassnett S

Invest Ophthalmol Vis Sci. 2011;52:2293-9

Washington University - Departmental Grant

Keyword: Cataract

Further analysis of the lens phenotype in Lim2-deficient mice.

Shi Y, De Maria AB, Wang H, Mathias RT, Fitzgerald PG, Bassnett S

Invest Ophthalmol Vis Sci. 2011;52:7332-9

Washington University - Departmental Grant

Keyword: Cataract

Mechanisms of blindness: Animal models provide insight into distinct CRX-associated retinopathies.

Tran NM, Chen S

Dev Dyn. 2014 Oct;243(10):1153-66

Washington University - Departmental Grant

Keywords: Retina/Retinal Diseases, Macular Dystrophy, Gene Research/Therapy

Mechanistically distinct mouse models for CRX-associated retinopathy.

Tran NM, Zhang A, Zhang X, Huecker JB, Hennig AK, and Chen S

PLoS Genet. 2014 Feb;10(2):e1004111

Washington University - Departmental Grant

Keywords: Retina/Retinal Diseases, Macular Dystrophy, Gene Research/Therapy

Revealing looping organization of mammalian photoreceptor genes using chromosome conformation capture (3C) assays.

Peng GH, Chen S

Methods Mol Biol. 2012;884:305-18

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

The orphan nuclear hormone receptor ERRβ controls rod photoreceptor survival.

Onishi A, Peng GH, Poth EM, Lee DA, Chen J, Alexis U, de Melo J, Chen S, Blackshaw S

Proc Natl Acad Sci USA 2010;107(25):11579-11584

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

The spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons.

de Melo J, Peng GH, Chen S, Blackshaw S

Development. 2011;138:2325-36

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

The transcription factor GTF2IRD1 regulates the topology and function of photoreceptors by modulating photoreceptor gene expression across the retina.

Masuda T, Zhang X, Berlinicke C, Wan J, Yerrabelli A, Conner EA, Kjellstrom S, Bush R, Thorgeirsson SS, Swaroop A, Chen S, Zack DJ

J Neurosci. 2014 Nov 12;34(46):15356-68

Washington University - Departmental Grant

Keywords: Retina/Retinal Diseases, Macular Dystrophy, Gene Research/Therapy

Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression.

Hennig AK, Peng GH, Chen S

PLoS One. 2013 Jul 26;8(7):e69721

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

Research Database

Research funded by RPB from 2010-2014 matching Lew R. Wasserman Merit Award