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Research to Prevent Blindness

Research Database

Harvard Medical School Research, funded by RPB from 2011-2014 matching Special Scholar Award

11 Citations, Sorted by Month and Year

October, 2014
A murine RP1 missense mutation causes protein mislocalization and slowly progressive photoreceptor degeneration.

Song D, Grieco S, Li Y, Hunter A, Chu S, Zhao L, Song Y, DeAngelis RA, Shi LY, Liu Q, Pierce EA, Nishina PM, Lambris JD, Dunaief JL

Am J Pathol. 2014 Oct;184(10):2721-9

Harvard Medical School - Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium.

Farkas MH, Lew DS, Sousa ME, Bujakowska K, Chatagnon J, Bhattacharya SS, Pierce EA, Nandrot EF

Am J Pathol. 2014 Oct;184(10):2641-52

Harvard Medical School - Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

September, 2014
Characterization of a spontaneous retinal neovascular mouse model.

Hasegawa E, Sweigard H, Husain D, Olivares AM, Chang B, Smith KE, Birsner AE, D'Amato RJ, Michaud NA, Han Y, Vavvas DG, Miller JW, Haider NB, Connor KM

PLoS One. 2014 Sep 4;9(9):e106507

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keyword: Retina/Retinal Diseases

July, 2014
Cytochrome P450-generated metabolites derived from omega-3 fatty acids attenuate neovascularization.

Yanai R, Mulki L, Hasegawa E, Takeuchi K, Sweigard H, Suzuki J, Gaissert P, Vavvas DG, Sonoda KH, Rothe M, Schunck WH, Miller JW, Connor KM

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9603-8

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keywords: AMD, Other: Ocular Neovascularization

The alternative complement pathway regulates pathological angiogenesis in the retina.

Sweigard JH, Yanai R, Gaissert P, Saint-Geniez M, Kataoka K, Thanos A, Stahl GL, Lambris JD, Connor KM

FASEB J. 2014 Jul;28(7):3171-82

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

May, 2014
Mammalian STE20-like kinase 2, not kinase 1, mediates photoreceptor cell death during retinal detachment.

Matsumoto H, Murakami Y, Kataoka K, Lin H, Connor KM, Miller JW, Zhou D, Avruch J, Vavvas DG

Cell Death Dis. 2014 May 29;5:e1269

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Strain difference in photoreceptor cell death after retinal detachment in mice.

Matsumoto H, Kataoka K, Tsoka P, Connor KM, Miller JW, Vavvas DG

Invest Ophthalmol Vis Sci. 2014 May 22;55(7):4165-74

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keywords: AMD, Retina/Retinal Diseases, Retinal Detachment

March, 2014
EGF-like-domain-7 is required for VEGF-induced Akt/ERK activation and vascular tube formation in an ex vivo angiogenesis assay.

Takeuchi K, Yanai R, Kumase F, Morizane Y, Suzuki J, Kayama M, Brodowska K, Nakazawa M, Miller JW, Connor KM, Vavvas DG

PLoS One. 2014 Mar 19;9(3):e91849

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keywords: AMD, Diabetic Retinopathy

August, 2013
Reversible reactivity by optic nerve astrocytes.

Sun D, Qu J, Jakobs TC

Glia. 2013 Aug;61(8):1218-35

Harvard Medical School - Special Scholar Award - Jakobs, Tatjana C / MD

Keyword: Glaucoma

June, 2013
The time course of gene expression during reactive gliosis in the optic nerve.

Qu J, Jakobs TC

PLoS One. 2013 Jun 27;8(6):e67094

Harvard Medical School - Special Scholar Award - Jakobs, Tatjana C / MD

Keyword: Glaucoma

February, 2013
Morphology of astrocytes in a glaucomatous optic nerve.

Lye-Barthel M, Sun D, Jakobs TC

Invest Ophthalmol Vis Sci. 2013 Feb 1;54(2):909-17

Harvard Medical School - Special Scholar Award - Jakobs, Tatjana C / MD

Keyword: Glaucoma

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