Research Database

Immunocytochemical evidence of Tulp1-dependent outer segment protein transport pathways in photoreceptor cells.

Grossman GH, Watson RF, Pauer GJ, Bollinger K, Hagstrom SA

Exp Eye Res. 2011 Nov;93(5):658-68

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Other: Photoreceptor, Other: Retinal Degeneration

Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.

Ding JD, Johnson LV, Herrmann R, Farsiu S, Smith SG, Groelle M, Mace BE, Sullivan P, Jamison JA, Kelly U, Harrabi O, Bollini SS, Dilley J, Kobayashi D, Kuang B, Li W, Pons J, Lin JC, Bowes Rickman C

Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):E279-87

Duke University - Departmental Grant

Keyword: AMD

Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.

Hu P, Herrmann R, Bednar A, Saloupis P, Dwyer MA, Yang P, Qi X, Thomas RS, Jaffe GJ, Boulton ME, McDonnell DP, Malek G

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):E4069-78

Duke University - Special Scholar Award - Malek, Goldis / PhD

Keywords: Retina/Retinal Diseases, Other: Oxidized Low Density Lipoprotein, Other: Retinal Pigment Epithelium, Other: Toxin Metabolism

Beta-secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.

Cai J, Qi X, Kociok N, Skosyrski S, Emilio A, Ruan Q, Han S, Liu L, Chen Z, Bowes Rickman C, Golde T, Grant MB, Saftig P, Serneels L, de Strooper B, Joussen AM, Boulton ME

EMBO Mol Med. 2012 Sep;4(9):980-91

Duke University - Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Angiogenesis, Other: Retina Pigment Epithelium

Exploring the potential role of the oxidant-activated transcription factor aryl hydrocarbon receptor in the pathogenesis of AMD.

Malek G, Dwyer M, McDonnell D

Adv Exp Med Biol. 2012;723:51-9

Duke University - Special Scholar Award - Malek, Goldis / PhD Departmental Grant

Keywords: AMD, Other: Oxidative Stress, Other: Mitochondria

A murine RP1 missense mutation causes protein mislocalization and slowly progressive photoreceptor degeneration.

Song D, Grieco S, Li Y, Hunter A, Chu S, Zhao L, Song Y, DeAngelis RA, Shi LY, Liu Q, Pierce EA, Nishina PM, Lambris JD, Dunaief JL

Am J Pathol. 2014 Oct;184(10):2721-9

Harvard Medical School - Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

Characterization of a spontaneous retinal neovascular mouse model.

Hasegawa E, Sweigard H, Husain D, Olivares AM, Chang B, Smith KE, Birsner AE, D'Amato RJ, Michaud NA, Han Y, Vavvas DG, Miller JW, Haider NB, Connor KM

PLoS One. 2014 Sep 4;9(9):e106507

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Cytochrome P450-generated metabolites derived from omega-3 fatty acids attenuate neovascularization.

Yanai R, Mulki L, Hasegawa E, Takeuchi K, Sweigard H, Suzuki J, Gaissert P, Vavvas DG, Sonoda KH, Rothe M, Schunck WH, Miller JW, Connor KM

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9603-8

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keywords: AMD, Other: Ocular Neovascularization

EGF-like-domain-7 is required for VEGF-induced Akt/ERK activation and vascular tube formation in an ex vivo angiogenesis assay.

Takeuchi K, Yanai R, Kumase F, Morizane Y, Suzuki J, Kayama M, Brodowska K, Nakazawa M, Miller JW, Connor KM, Vavvas DG

PLoS One. 2014 Mar 19;9(3):e91849

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keywords: AMD, Diabetic Retinopathy

Mammalian STE20-like kinase 2, not kinase 1, mediates photoreceptor cell death during retinal detachment.

Matsumoto H, Murakami Y, Kataoka K, Lin H, Connor KM, Miller JW, Zhou D, Avruch J, Vavvas DG

Cell Death Dis. 2014 May 29;5:e1269

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Morphology of astrocytes in a glaucomatous optic nerve.

Lye-Barthel M, Sun D, Jakobs TC

Invest Ophthalmol Vis Sci. 2013 Feb 1;54(2):909-17

Harvard Medical School - Special Scholar Award - Jakobs, Tatjana C / MD

Keyword: Glaucoma

Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium.

Farkas MH, Lew DS, Sousa ME, Bujakowska K, Chatagnon J, Bhattacharya SS, Pierce EA, Nandrot EF

Am J Pathol. 2014 Oct;184(10):2641-52

Harvard Medical School - Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

Reversible reactivity by optic nerve astrocytes.

Sun D, Qu J, Jakobs TC

Glia. 2013 Aug;61(8):1218-35

Harvard Medical School - Special Scholar Award - Jakobs, Tatjana C / MD

Keyword: Glaucoma

Strain difference in photoreceptor cell death after retinal detachment in mice.

Matsumoto H, Kataoka K, Tsoka P, Connor KM, Miller JW, Vavvas DG

Invest Ophthalmol Vis Sci. 2014 May 22;55(7):4165-74

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Physician-Scientist Award - Vavvas, Demetrios G / MD, PhD Departmental Grant

Keywords: AMD, Retina/Retinal Diseases, Retinal Detachment

The alternative complement pathway regulates pathological angiogenesis in the retina.

Sweigard JH, Yanai R, Gaissert P, Saint-Geniez M, Kataoka K, Thanos A, Stahl GL, Lambris JD, Connor KM

FASEB J. 2014 Jul;28(7):3171-82

Harvard Medical School - Special Scholar Award - Connor, Kip M / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

The time course of gene expression during reactive gliosis in the optic nerve.

Qu J, Jakobs TC

PLoS One. 2013 Jun 27;8(6):e67094

Harvard Medical School - Special Scholar Award - Jakobs, Tatjana C / MD

Keyword: Glaucoma

A cellular model for the investigation of fuchs' endothelial corneal dystrophy.

Kelliher C, Chakravarti S, Vij N, Mazur S, Stahl PJ, Engler C, Matthaei M, Yu SM, Jun AS

Exp Eye Res. 2011 Dec;93(6):880-8

Johns Hopkins University - Career Development Award Special Scholar Award

Keyword: Other: Corneal Dystrophy

Association of dry eye and inflammatory systemic diseases in a tertiary care-based sample.

Henrich CF, Ramulu PY, Akpek EK

Cornea. 2014 Aug;33(8):819-25

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keyword: Dry Eye

Association of vision loss and work status in the united states.

Sherrod CE, Vitale S, Frick KD, Ramulu PY

JAMA Ophthalmol. 2014 Oct;132(10):1239,42; quiz 1243-6

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keyword: Low Vision

Association of vision loss in glaucoma and age-related macular degeneration with IADL disability.

Hochberg C, Maul E, Chan ES, Van Landingham S, Ferrucci L, Friedman DS, Ramulu PY

Invest Ophthalmol Vis Sci. 2012 May 31;53(6):3201-6

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: AMD, Glaucoma

Associations among visual acuity and vision- and health-related quality of life among patients in the multicenter uveitis steroid treatment trial.

Frick KD, Drye LT, Kempen JH, Dunn JP, Holland GN, Latkany P, Rao NA, Sen HN, Sugar EA, Thorne JE, Wang RC, Holbrook JT, Multicenter Uveitis Steroid Treatment-MUST Trial Research Group

Invest Ophthalmol Vis Sci. 2012 Mar 9;53(3):1169-76

Johns Hopkins University - Special Scholar Award

Keywords: Uveitis/Infectious Diseases, Other: Quality of Life, Other: Visual Acuity

Association study in a south indian population supports rs1015213 as a risk factor for primary angle closure.

Duvesh R, Verma A, Venkatesh R, Kavitha S, Ramulu PY, Wojciechowski R, Sundaresan P

Invest Ophthalmol Vis Sci. 2013 Aug 19;54(8):5624-8

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Gene Research/Therapy, Glaucoma

Barriers to attending an eye examination after vision screening referral within a vulnerable population.

Gower EW, Silverman E, Cassard SD, Williams SK, Baldonado K, Friedman DS

J Health Care Poor Underserved. 2013 Aug;24(3):1042-52

Johns Hopkins University - Special Scholar Award

Keyword: Other: Vision Screening

Cataract surgery among medicare beneficiaries.

Schein OD, Cassard SD, Tielsch JM, Gower EW

Ophthalmic Epidemiol. 2012 Oct;19(5):257-64

Johns Hopkins University - Special Scholar Award

Keywords: Cataract, Epidemiology

Clinical and microbiological characteristics of fungal keratitis in the united states, 2001-2007: A multicenter study.

Keay LJ, Gower EW, Iovieno A, Oechsler RA, Alfonso EC, Matoba A, Colby K, Tuli SS, Hammersmith K, Cavanagh D, Lee SM, Irvine J, Stulting RD, Mauger TF, Schein OD

Ophthalmology. 2011 May;118(5):920-6

Johns Hopkins University - Special Scholar Award

Keywords: Cornea, Other: Ocular Infections

Clinical features and incidence rate of ocular complications in punctate inner choroidopathy.

Leung TG, Moradi A, Liu D, Nguyen QD, Dunn JP, Burkholder B, Butler NJ, Ostheimer T, Thorne JE

Retina. 2014 Aug;34(8):1666-74

Johns Hopkins University - Special Scholar Award

Keyword: Retina/Retinal Diseases

Clinical outcomes in patients with cytomegalovirus retinitis treated with ganciclovir implant.

Oktavec KC, Nolan K, Brown DM, Dunn JP, Livingston AG, Thorne JE

Am J Ophthalmol. 2012 Apr;153(4):728-33.e1-2

Johns Hopkins University - Special Scholar Award

Keyword: Retina/Retinal Diseases

Cost-effectiveness of fluocinolone acetonide implant versus systemic therapy for noninfectious intermediate, posterior, and panuveitis.

Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Sugar EA, Holbrook JT, Kempen JH, Burke AE, Drye LT, Thorne JE, Louis TA, Jabs DA, Altaweel MM, Frick KD

Ophthalmology. 2014 Oct;121(10):1855-62

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Current status of HIV infection and ocular disease.

Butler NJ, Thorne JE

Curr Opin Ophthalmol. 2012 Nov;23(6):517-22

Johns Hopkins University - Special Scholar Award

Keywords: Retina/Retinal Diseases, Other: AIDS

Definitions and standardization of a new grading scheme for eyelid contour abnormalities after trichiasis surgery.

Gower EW, West SK, Cassard SD, Munoz BE, Harding JC, Merbs SL

PLoS Negl Trop Dis. 2012;6(6):e1713

Johns Hopkins University - Special Scholar Award Senior Scientific Investigator Award

Keywords: Epidemiology, Other: Trachoma

Description and validation of a test to evaluate sustained silent reading.

Ramulu PY, Swenor BK, Jefferys JL, Rubin GS

Invest Ophthalmol Vis Sci. 2013 Jan 23;54(1):673-80

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Glaucoma, Other: Reading Tests

Detection of new-onset choroidal neovascularization using optical coherence tomography: The AMD DOC study.

Do DV, Gower EW, Cassard SD, Boyer D, Bressler NM, Bressler SB, Heier JS, Jefferys JL, Singerman LJ, Solomon SD

Ophthalmology. 2012 Apr;119(4):771-8

Johns Hopkins University - Special Scholar Award

Keywords: AMD, Imaging

Difficulty with out-loud and silent reading in glaucoma.

Ramulu PY, Swenor BK, Jefferys JL, Friedman DS, Rubin GS

Invest Ophthalmol Vis Sci. 2013 Jan 23;54(1):666-72

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Glaucoma, Other: Reading Tests

Driving habits in older patients with central vision loss.

Sengupta S, van Landingham SW, Solomon SD, Do DV, Friedman DS, Ramulu PY

Ophthalmology. 2014 Mar;121(3):727-32

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keyword: Low Vision

Driving patterns in older adults with glaucoma.

van Landingham SW, Hochberg C, Massof RW, Chan E, Friedman DS, Ramulu PY

BMC Ophthalmol. 2013 Feb 21;13:4,2415-13-4

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Glaucoma, Other: Driving

Evaluation of the united states public health service guidelines for discontinuation of anticytomegalovirus therapy after immune recovery in patients with cytomegalovirus retinitis.

Holbrook JT, Colvin R, van Natta ML, Thorne JE, Bardsley M, Jabs DA, Studies of Ocular Complications of AIDS (SOCA) Research Group

Am J Ophthalmol. 2011 Oct;152(4):628,637.e1

Johns Hopkins University - Special Scholar Award

Keywords: Retina/Retinal Diseases, Uveitis/Infectious Diseases

Factors predictive of remission of new-onset anterior uveitis.

Artornsombudh P, Pistilli M, Foster CS, Pujari SS, Gangaputra SS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Kempen JH

Ophthalmology. 2014 Mar;121(3):778-84

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Fear of falling and visual field loss from glaucoma.

Ramulu PY, van Landingham SW, Massof RW, Chan ES, Ferrucci L, Friedman DS

Ophthalmology. 2012 Jul;119(7):1352-8

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keyword: Glaucoma

Fear of falling in age-related macular degeneration.

van Landingham SW, Massof RW, Chan E, Friedman DS, Ramulu PY

BMC Ophthalmol. 2014 Jan 28;14:10,2415-14-10

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: AMD, Low Vision

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death.

Welsbie DS, Yang Z, Ge Y, Mitchell KL, Zhou X, Martin SE, Berlinicke CA, Hackler L,Jr, Fuller J, Fu J, Cao LH, Han B, Auld D, Xue T, Hirai S, Germain L, Simard-Bisson C, Blouin R, Nguyen JV, Davis CH, Enke RA, Boye SL, Merbs SL, Marsh-Armstrong N, Hauswirth WW, DiAntonio A, Nickells RW, Inglese J, Hanes J, Yau KW, Quigley HA, Zack DJ

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4045-50

Johns Hopkins University - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Functional improvement after one- and two-eye cataract surgery in the salisbury eye evaluation.

Lee BS, Munoz BE, West SK, Gower EW

Ophthalmology. 2013 May;120(5):949-55

Johns Hopkins University - Special Scholar Award Senior Scientific Investigator Award

Keyword: Cataract

Glaucomatous visual field loss associated with less travel from home.

Ramulu PY, Hochberg C, Maul EA, Chan ES, Ferrucci L, Friedman DS

Optom Vis Sci. 2014 Feb;91(2):187-93

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Glaucoma, Low Vision

High-dose intravenous corticosteroids for ocular inflammatory diseases.

Charkoudian LD, Ying GS, Pujari SS, Gangaputra S, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Kempen JH

Ocul Immunol Inflamm. 2012 Apr;20(2):91-9

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Identifying a clinically meaningful threshold for change in uveitic macular edema evaluated by optical coherence tomography.

Sugar EA, Jabs DA, Altaweel MM, Lightman S, Acharya N, Vitale AT, Thorne JE, Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group

Am J Ophthalmol. 2011 Dec;152(6):1044,1052.e5

Johns Hopkins University - Special Scholar Award

Keywords: Imaging, Uveitis/Infectious Diseases

Incidence of cytomegalovirus retinitis in the era of highly active antiretroviral therapy.

Sugar EA, Jabs DA, Ahuja A, Thorne JE, Danis RP, Meinert CL, Studies of the Ocular Complications of AIDS Research Group

Am J Ophthalmol. 2012 Jun;153(6):1016-24.e5

Johns Hopkins University - Special Scholar Award

Keyword: Retina/Retinal Diseases

Incidence of visual improvement in uveitis cases with visual impairment caused by macular edema.

Levin MH, Pistilli M, Daniel E, Gangaputra SS, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Kempen JH, Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study

Ophthalmology. 2014 Feb;121(2):588,95.e1

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Non-cytomegalovirus ocular opportunistic infections in patients with acquired immunodeficiency syndrome.

Gangaputra S, Drye L, Vaidya V, Thorne JE, Jabs DA, Lyon AT, Studies of the Ocular Complications of AIDS (SOCA) Research Group

Am J Ophthalmol. 2013 Feb;155(2):206-12.e5

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Outcomes of a vision screening program for underserved populations in the united states.

Friedman DS, Cassard SD, Williams SK, Baldonado K, O'Brien RW, Gower EW

Ophthalmic Epidemiol. 2013 Aug;20(4):201-11

Johns Hopkins University - Special Scholar Award

Keywords: Epidemiology, Other: Vision Screening

Periocular triamcinolone acetonide injections for control of intraocular inflammation associated with uveitis.

Salek SS, Leder HA, Butler NJ, Gan TJ, Dunn JP, Thorne JE

Ocul Immunol Inflamm. 2013 Aug;21(4):257-63

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Periocular triamcinolone acetonide injections for cystoid macular edema complicating noninfectious uveitis.

Leder HA, Jabs DA, Galor A, Dunn JP, Thorne JE

Am J Ophthalmol. 2011 Sep;152(3):441,448.e2

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Postcataract surgery endophthalmitis in the united states: Analysis of the complete 2003 to 2004 medicare database of cataract surgeries.

Keay L, Gower EW, Cassard SD, Tielsch JM, Schein OD

Ophthalmology. 2012 May;119(5):914-22

Johns Hopkins University - Special Scholar Award

Keywords: Cataract, Epidemiology, Other: Endophthalmitis

Postoperative outcomes after fluocinolone acetonide implant surgery in patients with birdshot chorioretinitis and other types of posterior and panuveitis.

Burkholder BM, Wang J, Dunn JP, Nguyen QD, Thorne JE

Retina. 2013 Sep;33(8):1684-93

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: The multicenter uveitis steroid treatment trial.

Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Kempen JH, Altaweel MM, Holbrook JT, Jabs DA, Louis TA, Sugar EA, Thorne JE

Ophthalmology. 2011 Oct;118(10):1916-26

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Rates and risk factors for unfavorable outcomes 6 weeks after trichiasis surgery.

Gower EW, Merbs SL, Munoz BE, Kello AB, Alemayehu W, Imeru A, West SK

Invest Ophthalmol Vis Sci. 2011 Apr 25;52(5):2704-11

Johns Hopkins University - Special Scholar Award

Keyword: Other: Trichiasis

Reading ability and reading engagement in older adults with glaucoma.

Nguyen AM, van Landingham SW, Massof RW, Rubin GS, Ramulu PY

Invest Ophthalmol Vis Sci. 2014 Jul 22;55(8):5284-90

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Glaucoma, Low Vision

Real-world assessment of physical activity in glaucoma using an accelerometer.

Ramulu PY, Maul E, Hochberg C, Chan ES, Ferrucci L, Friedman DS

Ophthalmology. 2012 Jun;119(6):1159-66

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keyword: Glaucoma

Regional variations and trends in the prevalence of diagnosed glaucoma in the medicare population.

Cassard SD, Quigley HA, Gower EW, Friedman DS, Ramulu PY, Jampel HD

Ophthalmology. 2012 Jul;119(7):1342-51

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Epidemiology, Glaucoma

Relationship between immediate post-operative appearance and 6-week operative outcome in trichiasis surgery.

Merbs SL, Harding JC, Cassard SD, Munoz BE, West SK, Gower EW

PLoS Negl Trop Dis. 2012;6(7):e1718

Johns Hopkins University - Special Scholar Award Senior Scientific Investigator Award

Keywords: Epidemiology, Other: Trachoma

Response of pediatric uveitis to tumor necrosis factor-alpha inhibitors.

Lerman MA, Burnham JM, Chang PY, Daniel E, Foster CS, Hennessy S, Jabs DA, Joffe MM, Kacmaz RO, Levy-Clarke GA, Mills MD, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Kempen JH

J Rheumatol. 2013 Aug;40(8):1394-403

Johns Hopkins University - Special Scholar Award

Keywords: Pediatric, Uveitis/Infectious Diseases

Retinal vessel caliber among people with acquired immunodeficiency syndrome: Relationships with disease-associated factors and mortality.

Gangaputra S, Kalyani PS, Fawzi AA, Van Natta ML, Hubbard LD, Danis RP, Thorne JE, Holland GN, Studies of the Ocular Complications of AIDS Research Group

Am J Ophthalmol. 2012 Mar;153(3):434-44.e1

Johns Hopkins University - Special Scholar Award

Keyword: Retina/Retinal Diseases

Retinal vessel caliber among people with acquired immunodeficiency syndrome: Relationships with visual function.

Kalyani PS, Fawzi AA, Gangaputra S, van Natta ML, Hubbard LD, Danis RP, Thorne JE, Holland GN, Studies of the Ocular Complications of AIDS Research Group

Am J Ophthalmol. 2012 Mar;153(3):428-33.e1

Johns Hopkins University - Special Scholar Award

Keyword: Retina/Retinal Diseases

Risk factors for loss of visual acuity among patients with uveitis associated with juvenile idiopathic arthritis: The systemic immunosuppressive therapy for eye diseases study.

Gregory AC,2nd, Kempen JH, Daniel E, Kacmaz RO, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study Research Group

Ophthalmology. 2013 Jan;120(1):186-92

Johns Hopkins University - Special Scholar Award

Keywords: Uveitis/Infectious Diseases, Other: Visual Acuity

Risk of choroidal neovascularization among the uveitides.

Baxter SL, Pistilli M, Pujari SS, Liesegang TL, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Kempen JH

Am J Ophthalmol. 2013 Sep;156(3):468-77.e2

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Risk of corticosteroid-induced hyperglycemia requiring medical therapy among patients with inflammatory eye diseases.

Udoetuk JD, Dai Y, Ying GS, Daniel E, Gangaputra S, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Kempen JH, Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study Research Group

Ophthalmology. 2012 Aug;119(8):1569-74

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Risk of elevated intraocular pressure and glaucoma in patients with uveitis: Results of the multicenter uveitis steroid treatment trial.

Friedman DS, Holbrook JT, Ansari H, Alexander J, Burke A, Reed SB, Katz J, Thorne JE, Lightman SL, Kempen JH, MUST Research Group

Ophthalmology. 2013 Aug;120(8):1571-9

Johns Hopkins University - Special Scholar Award

Keywords: Glaucoma, Uveitis/Infectious Diseases

Risk of hypotony in noninfectious uveitis.

Daniel E, Pistilli M, Pujari SS, Kacmaz RO, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Kempen JH

Ophthalmology. 2012 Nov;119(11):2377-85

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Risk of relapse in primary acute anterior uveitis.

Grunwald L, Newcomb CW, Daniel E, Kacmaz RO, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Kempen JH, Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study

Ophthalmology. 2011 Oct;118(10):1911-5

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

Subnormal cytokine profile in the tear fluid of keratoconus patients.

Jun AS, Cope L, Speck C, Feng X, Lee S, Meng H, Hamad A, Chakravarti S

PLoS One. 2011 Jan 27;6(1):e16437

Johns Hopkins University - Special Scholar Award

Keyword: Other: Keratoconus

Tattoo-associated uveitis.

Ostheimer TA, Burkholder BM, Leung TG, Butler NJ, Dunn JP, Thorne JE

Am J Ophthalmol. 2014 Sep;158(3):637-43.e1

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

The prevalence of concurrent hearing and vision impairment in the united states.

Swenor BK, Ramulu PY, Willis JR, Friedman D, Lin FR

JAMA Intern Med. 2013 Feb 25;173(4):312-3

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Epidemiology, Other: Hearing Loss, Other: Visual Impairment

The role of gender in juvenile idiopathic arthritis-associated uveitis.

Moradi A, Amin RM, Thorne JE

J Ophthalmol. 2014;2014:461078

Johns Hopkins University - Special Scholar Award

Keyword: Uveitis/Infectious Diseases

The role of the immune response in age-related macular degeneration.

Whitcup SM, Sodhi A, Atkinson JP, Holers VM, Sinha D, Rohrer B, Dick AD

Int J Inflam. 2013;2013:348092

Johns Hopkins University - Special Scholar Award - Sinha, Debasish / PhD

Keyword: AMD

Trachomatous trichiasis clamp vs standard bilamellar tarsal rotation instrumentation for trichiasis surgery: Results of a randomized clinical trial.

Gower EW, West SK, Harding JC, Cassard SD, Munoz BE, Othman MS, Kello AB, Merbs SL

JAMA Ophthalmol. 2013 Mar;131(3):294-301

Johns Hopkins University - Special Scholar Award Senior Scientific Investigator Award

Keywords: Uveitis/Infectious Diseases, Other: Trachoma

Transforming growth factor-beta signaling pathway activation in keratoconus.

Engler C, Chakravarti S, Doyle J, Eberhart CG, Meng H, Stark WJ, Kelliher C, Jun AS

Am J Ophthalmol. 2011 May;151(5):752,759.e2

Johns Hopkins University - Special Scholar Award

Keyword: Cornea

Transforming growth factor beta and insulin signal changes in stromal fibroblasts of individual keratoconus patients.

Foster J, Wu WH, Scott SG, Bassi M, Mohan D, Daoud Y, Stark WJ, Jun AS, Chakravarti S

PLoS One. 2014 Sep 23;9(9):e106556

Johns Hopkins University - Special Scholar Award

Keyword: Cornea

Treatment of sjogren's syndrome-associated dry eye an evidence-based review.

Akpek EK, Lindsley KB, Adyanthaya RS, Swamy R, Baer AN, McDonnell PJ

Ophthalmology. 2011 Jul;118(7):1242-52

Johns Hopkins University - Departmental Grant

Keyword: Dry Eye

Trends over time and regional variations in the rate of laser trabeculoplasty in the medicare population.

Jampel HD, Cassard SD, Friedman DS, Shekhawat NS, Whiteside-de Vos J, Quigley HA, Gower EW

JAMA Ophthalmol. 2014 Jun;132(6):685-90

Johns Hopkins University - Special Scholar Award

Keyword: Glaucoma

Visual characteristics of elderly night drivers in the salisbury eye evaluation driving study.

Kaleem MA, Munoz BE, Munro CA, Gower EW, West SK

Invest Ophthalmol Vis Sci. 2012 Aug 3;53(9):5161-7

Johns Hopkins University - Special Scholar Award

Keywords: Low Vision, Other: Driving

Visual impairment, uncorrected refractive error, and accelerometer-defined physical activity in the united states.

Willis JR, Jefferys JL, Vitale S, Ramulu PY

Arch Ophthalmol. 2012 Mar;130(3):329-35

Johns Hopkins University - Special Scholar Award - Ramulu, Pradeep Y / MD, MHS, PhD

Keywords: Epidemiology, Other: Visual Acuity

Adjustment versus no adjustment when using adjustable sutures in strabismus surgery.

Liebermann L, Hatt SR, Leske DA, Holmes JM

J AAPOS. 2013 Feb;17(1):38-42

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

A novel method for computerized measurement of episcleral venous pressure in humans.

Sit AJ, Ekdawi NS, Malihi M, McLaren JW

Exp Eye Res. 2011 Jun;92(6):537-44

Mayo Medical School - Departmental Grant

Keyword: Glaucoma

Anterior corneal aberrations after descemet's stripping endothelial keratoplasty for fuchs' endothelial dystrophy.

Patel SV, Baratz KH, Maguire LJ, Hodge DO, McLaren JW

Ophthalmology. 2012 Aug;119(8):1522-9

Mayo Medical School - Departmental Grant

Keyword: Cornea

Anterior keratocyte depletion in fuchs endothelial dystrophy.

Hecker LA, McLaren JW, Bachman LA, Patel SV

Arch Ophthalmol. 2011 May;129(5):555-61

Mayo Medical School - Departmental Grant

Keyword: Cornea

Assessing divergence in children with intermittent exotropia.

Liebermann L, Hatt SR, Leske DA, Yamada T, Mohney BG, Brodsky MC, Holmes JM

Strabismus. 2012 Mar;20(1):11-6

Mayo Medical School - Departmental Grant

Keywords: Pediatric, Strabismus/Amblyopia/Eye Movement Disorders

Atropine vs patching for treatment of moderate amblyopia: follow-up at 15 years of age of a randomized clinical trial.

Repka MX, Kraker RT, Holmes JM, Summers AI, Glaser SR, Barnhardt CN, Tien DR

JAMA Ophthalmol. 2014 Jul;132(7):799-805

Mayo Medical School - Departmental Grant

Keywords: Pediatric, Strabismus/Amblyopia/Eye Movement Disorders

Bourne WM, Patel SV.

Trousdale ER, Hodge DO, Baratz KH, Maguire LJ

Vision-related quality of life before and after keratoplasty for Fuchs’ endothelial dystrophy. 2014 Nov;121(11):2147-52

Mayo Medical School - Departmental Grant

Keyword: Cornea

Changes in health-related quality of life 1 year following strabismus surgery.

Hatt SR, Leske DA, Liebermann L, Holmes JM

Am J Ophthalmol. 2012 Apr;153(4):614-9

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Circadian variation of aqueous humor dynamics in older healthy adults.

Nau CB, Malihi M, McLaren JW, Hodge DO, Sit AJ

Invest Ophthalmol Vis Sci. 2013 Nov 15;54(12):7623-9

Mayo Medical School - Special Scholar Award

Keyword: Glaucoma

Clinical results of ab interno trabeculotomy using the trabectome for open-angle glaucoma: The mayo clinic series in rochester, minnesota.

Ahuja Y, Ma Khin Pyi S, Malihi M, Hodge DO, Sit AJ

Am J Ophthalmol. 2013 Nov;156(5):927-35.e2

Mayo Medical School - Departmental Grant

Keyword: Glaucoma

Comparing outcome criteria performance in adult strabismus surgery.

Hatt SR, Leske DA, Liebermann L, Holmes JM

Ophthalmology. 2012 Sep;119(9):1930-6

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Comprehensive assessment of genetic variants within TCF4 in Fuchs' endothelial corneal dystrophy.

Wieben ED, Aleff RA, Eckloff BW, Atkinson EJ, Baheti S, Middha S, Brown WL, Patel SV, Kocher JP, Baratz KH

Invest Ophthalmol Vis Sci 2014. Aug;55(9):6101-7

Mayo Medical School - Departmental Grant

Keyword: Cornea

Corneal abnormalities early in the course of Fuchs’ endothelial dystrophy.

Amin SR, Baratz KH, McLaren JW, Patel SV

Ophthalmology. 2014 Dec;121(12):2325-33

Mayo Medical School - Departmental Grant

Keyword: Cornea

Corneal endothelial cell changes 5 years after laser in situ keratomileusis: Femtosecond laser versus mechanical microkeratome.

Klingler KN, McLaren JW, Bourne WM, Patel SV

J Cataract Refract Surg. 2012 Dec;38(12):2125-30

Mayo Medical School - Departmental Grant

Keyword: Cornea

Corneal haze determined by confocal microscopy 2 years after descemet stripping with endothelial keratoplasty for fuchs corneal dystrophy.

Baratz KH, McLaren JW, Maguire LJ, Patel SV

Arch Ophthalmol. 2012 Jul 1;130(7):868-74

Mayo Medical School - Departmental Grant

Keyword: Cornea

Corneal sensitivity, blink rate, and corneal nerve density in progressive supranuclear palsy and parkinson disease.

Reddy VC, Patel SV, Hodge DO, Leavitt JA

Cornea. 2013 May;32(5):631-5

Mayo Medical School - Departmental Grant

Keyword: Cornea

Decreased corneal sensitivity and abnormal corneal nerves in fuchs endothelial dystrophy.

Ahuja Y, Baratz KH, McLaren JW, Bourne WM, Patel SV

Cornea. 2012 Nov;31(11):1257-63

Mayo Medical School - Departmental Grant

Keyword: Cornea

Delayed-onset symptomatic hyphema after ab interno trabeculotomy surgery.

Ahuja Y, Malihi M, Sit AJ

Am J Ophthalmol. 2012 Sep;154(3):476-80.e2

Mayo Medical School - Departmental Grant

Keyword: Glaucoma

Depressive symptoms associated with poor health-related quality of life in adults with strabismus.

Hatt SR, Leske DA, Liebermann L, Philbrick KL, Holmes JM

Ophthalmology. 2014 Oct;121(10):2070-1

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Distance versus near visual acuity in amblyopia.

Christoff A, Repka MX, Kaminski BM, Holmes JM, Pediatric Eye Disease Investigator Group

J AAPOS. 2011 Aug;15(4):342-4

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye

Effect of age on response to amblyopia treatment in children.

Holmes JM, Lazar EL, Melia BM, Astle WF, Dagi LR, Donahue SP, Frazier MG, Hertle RW, Repka MX, Quinn GE, Weise KK, Pediatric Eye Disease Investigator Group

Arch Ophthalmol. 2011 Nov;129(11):1451-7

Mayo Medical School - Departmental Grant

Keywords: Pediatric, Strabismus/Amblyopia/Eye

Effect of head and body position on intraocular pressure.

Malihi M, Sit AJ

Ophthalmology. 2012 May;119(5):987-91

Mayo Medical School - Departmental Grant

Keyword: Glaucoma

Endothelial image quality after descemet stripping with endothelial keratoplasty: A comparison of three microscopy techniques.

Raecker ME, McLaren JW, Kittleson KM, Patel SV

Eye Contact Lens. 2011 Jan;37(1):6-10

Mayo Medical School - Departmental Grant

Keyword: Cornea

Evaluation of the adult strabismus-20 (AS-20) questionnaire using rasch analysis.

Leske DA, Hatt SR, Liebermann L, Holmes JM

Invest Ophthalmol Vis Sci. 2012 May 4;53(6):2630-9

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Femtosecond laser versus mechanical microkeratome laser in situ keratomileusis for myopia: Metaanalysis of randomized controlled trials.

Zhang ZH, Jin HY, Suo Y, Patel SV, Montes-Mico R, Manche EE, Xu X

J Cataract Refract Surg. 2011 Dec;37(12):2151-9

Mayo Medical School - Special Scholar Award

Keyword: Cornea

Fusional convergence in childhood intermittent exotropia.

Hatt SR, Leske DA, Mohney BG, Brodsky MC, Holmes JM

Am J Ophthalmol. 2011 Aug;152(2):314-9

Mayo Medical School - Departmental Grant

Keywords: Pediatric, Strabismus/Amblyopia/Eye

Graft survival after penetrating keratoplasty.

Patel SV

Am J Ophthalmol. 2011 Mar;151(3):397-8

Mayo Medical School - Special Scholar Award

Keyword: Cornea Transplants

Graft survival and endothelial outcomes in the new era of endothelial keratoplasty.

Patel SV

Exp Eye Res. 2012 Feb;95(1):40-7

Mayo Medical School - Departmental Grant

Keyword: Cornea

Graft thickness, graft folds, and aberrations after descemet stripping endothelial keratoplasty for fuchs dystrophy.

Seery LS, Nau CB, McLaren JW, Baratz KH, Patel SV

Am J Ophthalmol. 2011 Dec;152(6):910-6

Mayo Medical School - Departmental Grant

Keyword: Cornea

Health-related quality of life in parents of children with intermittent exotropia.

Yamada T, Hatt SR, Leske DA, Holmes JM

J AAPOS. 2011 Apr;15(2):135-9

Mayo Medical School - Departmental Grant

Keywords: Strabismus/Amblyopia/Eye, Other: Intermittent Exotropia

Identifying masked superior oblique involvement in thyroid eye disease to avoid postoperative A-pattern exotropia and intorsion.

Holmes JM, Hatt SR, Bradley EA

J AAPOS. 2012 Jun;16(3):280-5

Mayo Medical School - Departmental Grant

Keywords: Strabismus/Amblyopia/Eye Movement Disorders, Thyroid Ophthalmology

Improved assessment of control in intermittent exotropia using multiple measures.

Hatt SR, Liebermann L, Leske DA, Mohney BG, Holmes JM

Am J Ophthalmol. 2011 Nov;152(5):872-6

Mayo Medical School - Departmental Grant

Keywords: Pediatric, Strabismus/Amblyopia/Eye

Improvement in specific function-related quality-of-life concerns after strabismus surgery in nondiplopic adults.

Liebermann L, Hatt SR, Leske DA, Holmes JM

J AAPOS. 2014 Apr;18(2):105-9

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Incidence, types, and lifetime risk of adult-onset strabismus.

Martinez-Thompson JM, Diehl NN, Holmes JM, Mohney BG

Ophthalmology. 2014 Apr;121(4):877-82

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Intraocular pressure variations: Causes and clinical significance.

Sit AJ

Can J Ophthalmol. 2014 Dec;49(6):484-8

Mayo Medical School - Departmental Grant

Keyword: Glaucoma

Intraoperative monitoring of torsion to prevent vertical deviations during augmented vertical rectus transposition surgery.

Holmes JM, Hatt SR, Leske DA

J AAPOS. 2012 Apr;16(2):136-40

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

In vivo confocal microscopy of fuchs endothelial dystrophy before and after endothelial keratoplasty.

Patel SV, McLaren JW

JAMA Ophthalmol. 2013 May;131(5):611-8

Mayo Medical School - Departmental Grant

Keyword: Cornea

In vivo confocal microscopy of the ocular surface: from bench to bedside.

Villani E, Baudouin C, Efron N, Hamrah P, Kojima T, Patel SV, Pflugfelder SC, Zhivov A, Dogru M

Curr Eye Res. 2014 Mar;39(3):213-31

Mayo Medical School - Departmental Grant

Keyword: Cornea

Lessons from the amblyopia treatment studies.

Repka MX, Holmes JM

Ophthalmology. 2012 Apr;119(4):657-8

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Long-term trends in glaucoma-related blindness in Olmsted County, Minnesota.

Malihi M, Moura Filho ER, Hodge DO, Sit AJ

Ophthalmology. 2014 Jan;121(1):134-41

Mayo Medical School - Departmental Grant

Keyword: Glaucoma

Measurement of episcleral venous pressure.

Sit AJ, McLaren JW

Exp Eye Res. 2011 Sep;93(3):291-8

Mayo Medical School - Special Scholar Award

Keyword: Glaucoma

Modeling the effect of forward scatter and aberrations on visual acuity after endothelial keratoplasty.

McLaren JW, Patel SV

Invest Ophthalmol Vis Sci. 2012 Aug 15;53(9):5545-51

Mayo Medical School - Departmental Grant

Keyword: Cornea

Objective assessment of the corneal endothelium in Fuchs' endothelial dystrophy.

McLaren JW, Bachman LA, Kane KM, Patel SV

Invest Ophthalmol Vis Sci. 2014 Feb;55(2):1184-90

Mayo Medical School - Departmental Grant

Keyword: Cornea

Quality of vision in patients with fuchs endothelial dystrophy and after descemet stripping endothelial keratoplasty.

van der Meulen IJ, Patel SV, Lapid-Gortzak R, Nieuwendaal CP, McLaren JW, van den Berg TJ

Arch Ophthalmol. 2011 Dec;129(12):1537-42

Mayo Medical School - Departmental Grant

Keyword: Cornea

Quantifying diplopia with a questionnaire.

Holmes JM, Liebermann L, Hatt SR, Smith SJ, Leske DA

Ophthalmology. 2013 Jul;120(7):1492-6

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Retinal point-spread function after corneal transplantation for fuchs' dystrophy.

Seery LS, McLaren JW, Kittleson KM, Patel SV

Invest Ophthalmol Vis Sci. 2011 Feb 22;52(2):1003-8

Mayo Medical School - Departmental Grant

Keyword: Cornea Transplants

Scleral lenses in the management of ocular surface disease.

Schornack MM, Pyle J, Patel SV

Ophthalmology. 2014 Jul;121(7):1398-405

Mayo Medical School - Departmental Grant

Keyword: Cornea

Silica hybrid for corneal replacement: Optical, biomechanical, and ex vivo biocompatibility studies.

DiVito MD, Rudisill SG, Stein A, Patel SV, McLaren JW, Hubel A

Invest Ophthalmol Vis Sci. 2012 Dec 13;53(13):8192-9

Mayo Medical School - Departmental Grant

Keyword: Cornea

Specific health-related quality of life concerns in children with intermittent exotropia.

Yamada T, Hatt SR, Leske DA, Holmes JM

Strabismus. 2012 Dec;20(4):145-51

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Spectacle wear in children reduces parental health-related quality of life.

Yamada T, Hatt SR, Leske DA, Holmes JM

J AAPOS. 2011 Feb;15(1):24-8

Mayo Medical School - Departmental Grant

Keywords: Strabismus/Amblyopia/Eye, Other: Intermittent Exotropia

Stability of near stereoacuity in childhood intermittent exotropia.

Holmes JM, Leske DA, Hatt SR, Brodsky MC, Mohney BG

J AAPOS. 2011 Oct;15(5):462-7

Mayo Medical School - Departmental Grant

Keywords: Strabismus/Amblyopia/Eye, Other: Intermittent Exotropia

Stereoacuity thresholds before and after visual acuity testing.

Smith SJ, Leske DA, Hatt SR, Holmes JM

Ophthalmology. 2012 Jan;119(1):164-9

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Successful treatment of diplopia with prism improves health-related quality of life.

Hatt SR, Leske DA, Liebermann L, Holmes JM

Am J Ophthalmol. 2014 Jun;157(6):1209-13

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Sustained improvement of reading symptoms following botulinum toxin A injection for convergence insufficiency.

Saunte JP, Holmes JM

Strabismus. 2014 Sep;22(3):95-9

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Torsional augmentation for the treatment of lateropulsion and torticollis in partial ocular tilt reaction.

Brodsky MC, Holmes JM

J AAPOS. 2012 Apr;16(2):141-4

Mayo Medical School - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Variability of angle of deviation measurements in children with intermittent exotropia.

Hatt SR, Leske DA, Liebermann L, Mohney BG, Holmes JM

J AAPOS. 2012 Apr;16(2):120-4

Mayo Medical School - Departmental Grant

Keywords: Pediatric, Strabismus/Amblyopia/Eye Movement Disorders

Differential effects of rapamycin on rods and cones during light-induced stress in albino mice.

Kunchithapautham K, Coughlin B, Lemasters JJ, Rohrer B

Invest Ophthalmol Vis Sci. 2011 May;52(6):2967-75

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

Gene therapy rescues cone structure and function in the three-month-old rd12 mouse: A model for mid-course RPE65 Leber congenital amaurosis.

Li X, Li W, Dai X, Kong F, Zeng Q, Zhou X, Lü F, Chang B, Rohrer B, Hauswirth WW, Qu J, Pang JJ

Invest Ophthalmol Vis Sci. 2011 Jan;52(1):7-15

Medical University of South Carolina - Departmental Grant

Keyword: Other: Leber Congenital Amaurosis

Matrix metalloproteinase activity creates pro-angiogenic environment in primary human retinal pigment epithelial cells exposed to complement.

Bandyopadhyay M, Rohrer B

Invest Ophthalmol Vis Sci. 2012 Apr 18;53(4):1953-61

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive VEGF secretion in retinal pigment epithelium monolayers.

Kunchithapautham K, Rohrer B

J Biol Chem. 2011 Jul;286(27):23717-24

Medical University of South Carolina - Departmental Grant

Keyword: AMD

Systemic human CR2-targeted complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal neovascularization.

Rohrer B, Coughlin B, Bandyopadhyay M, Holers VM

J Ocul Pharmacol Ther. 2012 Aug;28(4):402-9

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization.

Rohrer B, Coughlin B, Kunchithapautham K, Long Q, Tomlinson S, Takahashi K, Holers VM

Mol Immunol. 2011 Mar;48(6-7):e1-8

Medical University of South Carolina - Departmental Grant

Keyword: AMD

Sustained ocular hypertension induces dendritic degeneration of mouse retinal ganglion cells that depends on cell type and location.

Feng L, Zhao Y, Yoshida M, Chen H, Yang JF, Kim TS, Cang J, Troy JB, Liu X

Invest Ophthalmol Vis Sci. 2013 Feb 7;54(2):1106-17

Northwestern University - Special Scholar Award - Liu, Xiaorong / PhD Departmental Grant

Keyword: Glaucoma

Differential effects of caveolin-1 and -2 knockdown on aqueous outflow and altered extracellular matrix turnover in caveolin-silenced trabecular meshwork cells.

Aga M, Bradley JM, Wanchu R, Yang YF, Acott TS, Keller KE

Invest Ophthalmol Vis Sci. 2014 Aug 7;55(9):5497-509.

Oregon Health & Science University - Special Scholar Award - Keller, Kate E / PhD Departmental Grant

Keyword: Glaucoma

Interleukin-20 receptor expression in the trabecular meshwork and its implication in glaucoma.

Keller KE, Yang YF, Sun YY, Sykes R, Gaudette ND, Samples JR, Acott TS, Wirtz MK

J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):267-76.

Oregon Health & Science University - Special Scholar Award - Keller, Kate E / PhD Departmental Grant

Keyword: Glaucoma

Intraocular pressure homeostasis: Maintaining balance in a high-pressure environment.

Acott TS, Kelley MJ, Keller KE, Vranka JA, Abu-Hassan DW, Li X, Aga M, Bradley JM

J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):94-101.

Oregon Health & Science University - Special Scholar Award - Keller, Kate E / PhD Departmental Grant

Keyword: Glaucoma

IKK2 inhibition attenuates laser-induced choroidal neovascularization.

Lu H, Lu Q, Gaddipati S, Kasetti RB, Wang W, Pasparakis M, Kaplan HJ, Li Q

PloS One. 2014 Jan;9(1):e87530.

University of Louisville - Special Scholar Award - Li, Qiutang / PhD Special Scholar Award - Lu, Qingxian / PhD Departmental Grant

Keyword: Other: Neovascularization

TAM receptor knockout mice are susceptible to retinal autoimmune induction.

Ye F, Li Q, Ke Y, Lu Q, Han L, Kaplan HJ, Shao H, Lu Q

Invest Ophthalmol Vis Sci. 2011 Jun 16;52(7):4239-46

University of Louisville - Special Scholar Award - Lu, Qingxian / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Caspase inhibition with XIAP as an adjunct to AAV vector gene-replacement therapy: Improving efficacy and prolonging the treatment window.

Yao J, Jia L, Khan N, Zheng QD, Moncrief A, Hauswirth WW, Thompson DA, Zacks DN

PLoS One. 2012;7(5):e37197

University of Michigan - Departmental Grant

Keywords: Gene Research/Therapy, Retina/Retinal Diseases

Cell and gene therapy.

Rao RC, Zacks DN

Dev Ophthalmol. 2014 53:167-77

University of Michigan - Special Scholar Award

Keyword: Gene Research/Therapy

Circadian and non-circadian modulation of autophagy in photoreceptors and retinal pigment epithelium.

Yao J, Jia L, Shelby SJ, Ganios AM, Feathers K, Thompson DA, Zacks DN

Invest Ophthalmol Vis Sci. 2014 Apr;55(5):3237-46

University of Michigan - Departmental Grant

Keywords: Retina/Retinal Diseases, AMD, Retinitis Pigmentosa

Control of photoreceptor autophagy after retinal detachment: the switch from survival to death.

Chinskey ND, Zheng QD, Zacks DN

Invest Ophthalmol Vis Sci. 2014 Feb;55(2):688-95

University of Michigan - Special Scholar Award

Keywords: Retina/Retinal Diseases, Retinal Detachment

Rates of nonexudative and exudative age-related macular degeneration among asian american ethnic groups.

Stein JD, Vanderbeek BL, Talwar N, Nan B, Musch DC, Zacks DN

Invest Ophthalmol Vis Sci. 2011 Aug 29;52(9):6842-8

University of Michigan - Departmental Grant

Keywords: AMD, Other: Epidemiology

Retinal cell death and current strategies in retinal neuroprotection.

Chinskey ND, Besirli CG, Zacks DN

Curr Opin Ophthalmol. 2014 May;25(3):228-33

University of Michigan - Special Scholar Award

Keywords: Retina/Retinal Diseases, Retinal Detachment

Beyond the cherry-red spot: Ocular manifestations of sphingolipid-mediated neurodegenerative and inflammatory disorders.

Chen H, Chan AY, Stone DU, Mandal NA

Surv Ophthalmol. 2014 Jan; 59(1):64-76.

University of Oklahoma Health Sciences Center - Special Scholar Award - Mandal, Nawajes / PhD

Keywords: Retina/Retinal Diseases, Gene Research/Therapy, AMD, Diabetic Retinopathy

Caveolin-1 increases proinflammatory chemoattractants and blood-retinal barrier breakdown but decreases leukocyte recruitment in inflammation.

Li X, Gu X, Boyce TM, Zheng M, Reagan AM, Qi H, Mandal N, Cohen AW, Callegan MC, Carr, DJ, Elliott MH

Invest Ophthalmol Vis Sci 2014 Oct;55(10): 6224-6234.

University of Oklahoma Health Sciences Center - Special Scholar Award - Mandal, Nawajes / PhD Special Scholar Award - Elliott, Michael H / PhD Departmental Grant

Keywords: AMD, Diabetic Retinopathy, Uveitis/Infectious Diseases

In vivo effect of mutant ELOVL4 on the expression and function of wild-type ELOVL4.

Mandal NA, Tran JT, Zheng L, Wilkerson JL, Brush RS, McRae J, Agbaga MP, Zhang K, Petrukhin K, Ayyagari R, Anderson RE

Invest Ophthalmol Vis Sci. 2014 Apr;55(4):2705-13.

University of Oklahoma Health Sciences Center - Special Scholar Award - Mandal, Nawajes / PhD

Keywords: Retina/Retinal Diseases, Gene Research/Therapy, AMD

Leukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium.

Chucair-Elliott AJ, Elliott MH, Wang J, Moiseyev GP, Ma JX, Politi LE, Rotstein NP, Akira S, Uematsu S, Ash JD

J Biol Chem. 2012 Jul 13;287(29):24092-102

University of Oklahoma Health Sciences Center - Special Scholar Award - Elliott, Michael H / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Loss of caveolin-1 causes blood-retinal barrier breakdown, venous enlargement, and mural cell alteration.

Gu X, Fliesler SJ, Zhao Y, Stallcup WB, Cohen AW, Elliott MH

Am J Path. 2014 Feb;184(2):541-555.

University of Oklahoma Health Sciences Center - Special Scholar Award - Elliott, Michael H / PhD Departmental Grant

Keywords: Diabetic Retinopathy, Glaucoma, Retinal Vein and Artery Occlusion

Loss of caveolin-1 impairs retinal function due to disturbance of subretinal microenvironment.

Li X, McClellan ME, Tanito M, Garteiser P, Towner R, Bissig D, Berkowitz BA, Fliesler SJ, Woodruff ML, Fain GL, Birch DG, Khan MS, Ash JD, Elliott MH

J Biol Chem. 2012 May 11;287(20):16424-34

University of Oklahoma Health Sciences Center - Special Scholar Award - Elliott, Michael H / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Baseline risk factors that predict the development of open-angle glaucoma in a population: The los angeles latino eye study.

Jiang X, Varma R, Wu S, Torres M, Azen SP, Francis BA, Chopra V, Nguyen BB, Los Angeles Latino Eye Study Group

Ophthalmology. 2012 Nov;119(11):2245-53

University of Southern California - Special Scholar Award

Keyword: Glaucoma

Four-year incidence of open-angle glaucoma and ocular hypertension: The los angeles latino eye study.

Varma R, Wang D, Wu C, Francis BA, Nguyen BB, Chopra V, Memarzadeh F, Torres M, Azen SP, Los Angeles Latino Eye Study Group

Am J Ophthalmol. 2012 Aug;154(2):315,325.e1

University of Southern California - Special Scholar Award

Keyword: Glaucoma

General health-related quality of life in preschool children with strabismus or amblyopia.

Wen G, McKean-Cowdin R, Varma R, Tarczy-Hornoch K, Cotter SA, Borchert M, Azen S, Multi-ethnic Pediatric Eye Disease Study Group

Ophthalmology. 2011 Mar;118(3):574-80

University of Southern California - Departmental Grant

Keyword: Pediatric

Prevalence of astigmatism in 6- to 72-month-old african american and hispanic children: The multi-ethnic pediatric eye disease study.

Fozailoff A, Tarczy-Hornoch K, Cotter S, Wen G, Lin J, Borchert M, Azen S, Varma R, Writing Committee for the MEPEDS Study Group

Ophthalmology. 2011 Feb;118(2):284-93

University of Southern California - Departmental Grant

Keyword: Pediatric

Risk factors associated with childhood strabismus: The multi-ethnic pediatric eye disease and baltimore pediatric eye disease studies.

Cotter SA, Varma R, Tarczy-Hornoch K, McKean-Cowdin R, Lin J, Wen G, Wei J, Borchert M, Azen SP, Torres M, Tielsch JM, Friedman DS, Repka MX, Katz J, Ibironke J, Giordano L, The Joint Writing Committee for the Multi-Ethnic Pediatric Eye Disease Study and the Baltimore Pediatric Eye Disease Study Groups

Ophthalmology. 2011 Nov;118(11):2251-61

University of Southern California - Departmental Grant

Keywords: Pediatric, Strabismus/Amblyopia/Eye

Risk factors for astigmatism in preschool children: The multi-ethnic pediatric eye disease and baltimore pediatric eye disease studies.

McKean-Cowdin R, Varma R, Cotter SA, Tarczy-Hornoch K, Borchert MS, Lin JH, Wen G, Azen SP, Torres M, Tielsch JM, Friedman DS, Repka MX, Katz J, Ibironke J, Giordano L, Multi-Ethnic Pediatric Eye Disease Study and the Baltimore Pediatric Eye Disease Study Groups

Ophthalmology. 2011 Oct;118(10):1974-81

University of Southern California - Departmental Grant

Keyword: Pediatric

Risk factors for cortical, nuclear, posterior subcapsular, and mixed lens opacities: The los angeles latino eye study.

Richter GM, Torres M, Choudhury F, Azen SP, Varma R, Los Angeles Latino Eye Study Group

Ophthalmology. 2012 Mar;119(3):547-54

University of Southern California - Special Scholar Award

Keywords: Cataract, Glaucoma

Risk factors for decreased visual acuity in preschool children: The multi-ethnic pediatric eye disease and baltimore pediatric eye disease studies.

Tarczy-Hornoch K, Varma R, Cotter SA, McKean-Cowdin R, Lin JH, Borchert MS, Torres M, Wen G, Azen SP, Tielsch JM, Friedman DS, Repka MX, Katz J, Ibironke J, Giordano L, Joint Writing Committee for the Multi-Ethnic Pediatric Eye Disease Study and the Baltimore Pediatric Eye Disease Study Groups

Ophthalmology. 2011 Nov;118(11):2262-73

University of Southern California - Departmental Grant

Keyword: Pediatric

Risk factors for four-year incidence and progression of age-related macular degeneration: The los angeles latino eye study.

Choudhury F, Varma R, McKean-Cowdin R, Klein R, Azen SP, Los Angeles Latino Eye Study Group

Am J Ophthalmol. 2011 Sep;152(3):385-95

University of Southern California - Departmental Grant

Keyword: AMD

Risk factors for four-year incident visual impairment and blindness: The los angeles latino eye study.

Yonekawa Y, Varma R, Choudhury F, Torres M, Azen SP, Los Angeles Latino Eye Study Group

Ophthalmology. 2011 Sep;118(9):1790-7

University of Southern California - Departmental Grant

Keyword: Low Vision

Risk factors for hyperopia and myopia in preschool children the multi-ethnic pediatric eye disease and baltimore pediatric eye disease studies.

Borchert MS, Varma R, Cotter SA, Tarczy-Hornoch K, McKean-Cowdin R, Lin JH, Wen G, Azen SP, Torres M, Tielsch JM, Friedman DS, Repka MX, Katz J, Ibironke J, Giordano L, Multi-Ethnic Pediatric Eye Disease Study and the Baltimore Pediatric Eye Disease Study Groups

Ophthalmology. 2011 Oct;118(10):1966-73

University of Southern California - Departmental Grant

Keyword: Pediatric

Risk factors for incident cortical, nuclear, posterior subcapsular, and mixed lens opacities: The los angeles latino eye study.

Richter GM, Choudhury F, Torres M, Azen SP, Varma R, Los Angeles Latino Eye Study Group

Ophthalmology. 2012 Oct;119(10):2040-7

University of Southern California - Special Scholar Award

Keywords: Cataract, Glaucoma

Severity of diabetic retinopathy and health-related quality of life: The los angeles latino eye study.

Mazhar K, Varma R, Choudhury F, McKean-Cowdin R, Shtir CJ, Azen SP, Los Angeles Latino Eye Study Group

Ophthalmology. 2011 Apr;118(4):649-55

University of Southern California - Departmental Grant

Keyword: Diabetic Retinopathy

The impact of change in visual field on health-related quality of life: The los angeles latino eye study.

Patino CM, Varma R, Azen SP, Conti DV, Nichol MB, McKean-Cowdin R, Los Angeles Latino Eye Study Group

Ophthalmology. 2011 Jul;118(7):1310-7

University of Southern California - Departmental Grant

Keyword: Low Vision

Validity of self-reported eye disease and treatment in a population-based study: The los angeles latino eye study.

Patty L, Wu C, Torres M, Azen S, Varma R, Los Angeles Latino Eye Study Group

Ophthalmology. 2012 Sep;119(9):1725-30

University of Southern California - Special Scholar Award

Keywords: AMD, Cataract, Glaucoma

Cyclin D1 inactivation extends proliferation and alters histogenesis in the postnatal mouse retina.

Das G, Clark AM, Levine EM

Dev Dyn. 2012 May;241(5):941-52

University of Utah - Departmental Grant

Keyword: Retina/Retinal Diseases

Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function.

Vazquez-Chona FR, Swan A, Ferrell WD, Jiang L, Baehr W, Chien W, Fero M, Marc RE, Levine EM

BMC Neurosci. 2011;12:98

University of Utah - Departmental Grant

Keyword: Retina/Retinal Diseases

Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding.

Zou C, Levine EM

PLoS Genet. 2012 Sep;8(9):e1002924

University of Utah - Departmental Grant

Keywords: Stem Cell Research/Therapy, Other: Ocular Birth Defects-Microphthalmia and Anophthalmia

Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment.

Meyer JS, Howden SE, Wallace KA, Verhoeven AD, Wright LS, Capowski EE, Pinilla I, Martin JM, Tian S, Stewart R, Pattnaik B, Thomson JA, Gamm DM

Stem Cells. 2011 Aug;29(8):1206-18

University of Wisconsin - Special Scholar Award

Keyword: Retina/Retinal Diseases

Ascorbic acid prevents high glucose-induced apoptosis in human brain pericytes.

May JM, Jayagopal A, Qu ZC, Parker WH

Biochem Biophys Res Commun. 2014 Sep 12;452(1):112-7.

Vanderbilt University - Special Scholar Award - Jayagopal, Ashwath / PhD Departmental Grant

Keyword: Nanotechnology/Drug Delivery

Bves modulates tight junction associated signaling.

Russ PK, Pino CJ, Williams CS, Bader DM, Haselton FR, Chang MS

PLoS One. 20116(1):e14563

Vanderbilt University - Departmental Grant

Keyword: Cornea

BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma.

Williams CS, Zhang B, Smith JJ, Jayagopal A, Barrett CW, Pino C, Russ P, Presley SH, Peng D, Rosenblatt DO, Haselton FR, Yang JL, Washington MK, Chen X, Eschrich S, Yeatman TJ, El-Rifai W, Beauchamp RD, Chang MS

J Clin Invest. 2011 Oct 3;121(10):4056-69

Vanderbilt University - Departmental Grant

Keyword: Cornea