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Research to Prevent Blindness

Research Database

Case Western Reserve University Research, funded by RPB in 2014 matching Departmental Grant

9 Citations, Sorted by Month and Year

August, 2014
DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.

Sundermeier TR, Zhang N, Vinberg F, Mustafi D, Kohno H, Golczak M, Bai X, Maeda A, Kefalov VJ, Palczewski K

FASEB J. 2014 Aug;28(8):3780-91

Case Western Reserve University - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

June, 2014
All-trans-retinal induces bax activation via DNA damage to mediate retinal cell apoptosis.

Sawada O, Perusek L, Kohno H, Howell SJ, Maeda A, Matsuyama S, Maeda T

Exp Eye Res. 2014 Jun;123:27-36

Case Western Reserve University - Departmental Grant

Keyword: Retina/Retinal Diseases

UVA light-excited kynurenines oxidize ascorbate and modify lens proteins through the formation of advanced glycation end products: Implications for human lens aging and cataract formation.

Linetsky M, Raghavan CT, Johar K, Fan X, Monnier VM, Vasavada AR, Nagaraj RH

J Biol Chem. 2014 Jun 13;289(24):17111-23

Case Western Reserve University - Departmental Grant

Keyword: Cataract

April, 2014
Aspergillus and fusarium corneal infections are regulated by Th17 cells and IL-17-producing neutrophils.

Taylor PR, Leal SM,Jr, Sun Y, Pearlman E

J Immunol. 2014 Apr 1;192(7):3319-27

Case Western Reserve University - Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.

Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A

J Immunol. 2014 Apr 15;192(8):3816-27

Case Western Reserve University - Departmental Grant

Keyword: Retina/Retinal Diseases

Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice.

Maeda A, Palczewska G, Golczak M, Kohno H, Dong Z, Maeda T, Palczewski K

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1428-37

Case Western Reserve University - Departmental Grant

Keyword: Retina/Retinal Diseases

February, 2014
Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORgammat and dectin-2.

Taylor PR, Roy S, Leal SM,Jr, Sun Y, Howell SJ, Cobb BA, Li X, Pearlman E

Nat Immunol. 2014 Feb;15(2):143-51

Case Western Reserve University - Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

Pro-inflammatory cytokines downregulate Hsp27 and cause apoptosis of human retinal capillary endothelial cells.

Nahomi RB, Palmer A, Green KM, Fort PE, Nagaraj RH

Biochim Biophys Acta. 2014 Feb;1842(2):164-74

Case Western Reserve University - Departmental Grant

Keyword: Retina/Retinal Diseases

January, 2014

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