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Research to Prevent Blindness

Research Database

University of California, San Diego Research, funded by RPB from 2010-2014 matching Senior Scientific Investigator Award to Zhang, Kang / MD, PhD

8 Citations, Sorted by Month and Year

July, 2013
Common variant in VEGFA and response to anti-VEGF therapy for neovascular age-related macular degeneration.

Zhao L, Grob S, Avery R, Kimura A, Pieramici D, Lee J, Rabena M, Ortiz S, Quach J, Cao G, Luo H, Zhang M, Pei M, Song Y, Tornambe P, Goldbaum M, Ferreyra H, Kozak I, Zhang K

Curr Mol Med. 2013 Jul;13(6):929-34

University of California, San Diego - Senior Scientific Investigator Award - Zhang, Kang / MD, PhD Departmental Grant

Keywords: AMD, Gene Research/Therapy, Imaging, Retina/Retinal Diseases

TCF7L2 variation and proliferative diabetic retinopathy.

Luo J, Zhao L, Chen AY, Zhang X, Zhu J, Zhao J, Ouyang H, Luo H, Song Y, Lee J, Patel SH, Shaw PX, Sadda S, Zhuo Y, Rosenfeld MG, Zhang K

Diabetes. 2013 Jul;62(7):2613-7

University of California, San Diego - Senior Scientific Investigator Award - Zhang, Kang / MD, PhD Departmental Grant

Keywords: Diabetic Retinopathy, Retinal Detachment, Other: Retinal Neovascularization

August, 2012
Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids.

Shaw PX, Zhang L, Zhang M, Du H, Zhao L, Lee C, Grob S, Lim SL, Hughes G, Lee J, Bedell M, Nelson MH, Lu F, Krupa M, Luo J, Ouyang H, Tu Z, Su Z, Zhu J, Wei X, Feng Z, Duan Y, Yang Z, Ferreyra H, Bartsch DU, Kozak I, Zhang L, Lin F, Sun H, Feng H, Zhang K

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13757-62

University of California, San Diego - Senior Scientific Investigator Award - Zhang, Kang / MD, PhD Departmental Grant

Keywords: AMD, Other: Genotype

June, 2012
A novel compound heterozygous mutation in the BEST1 gene causes autosomal recessive best vitelliform macular dystrophy.

Zhao L, Grob S, Corey R, Krupa M, Luo J, Du H, Lee C, Hughes G, Lee J, Quach J, Zhu J, Shaw PX, Kozak I, Zhang K

Eye (Lond). 2012 Jun;26(6):866-71

University of California, San Diego - Senior Scientific Investigator Award - Zhang, Kang / MD, PhD Departmental Grant

Keywords: Gene Research/Therapy, Macular Dystrophy, Other: Mutations

Ophthalmic drug discovery: Novel targets and mechanisms for retinal diseases and glaucoma.

Zhang K, Zhang L, Weinreb RN

Nat Rev Drug Discov. 2012 Jun 15;11(7):541-59

University of California, San Diego - Senior Scientific Investigator Award - Zhang, Kang / MD, PhD Departmental Grant

Keywords: AMD, Glaucoma, Other: Ophthalmic Drug

April, 2012
Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats.

Deng WT, Dinculescu A, Li Q, Boye SL, Li J, Gorbatyuk MS, Pang J, Chiodo VA, Matthes MT, Yasumura D, Liu L, Alkuraya FS, Zhang K, Vollrath D, LaVail MM, Hauswirth WW

Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904

University of California, San Diego - Senior Scientific Investigator Award - Zhang, Kang / MD, PhD Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

March, 2012
Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function.

Harkewicz R, Du H, Tong Z, Alkuraya H, Bedell M, Sun W, Wang X, Hsu YH, Esteve-Rudd J, Hughes G, Su Z, Zhang M, Lopes VS, Molday RS, Williams DS, Dennis EA, Zhang K

J Biol Chem. 2012 Mar 30;287(14):11469-80

University of California, San Diego - Senior Scientific Investigator Award - Zhang, Kang / MD, PhD Departmental Grant

Keywords: Macular Dystrophy, Retina/Retinal Diseases, Other: ELOVL4 Protein

January, 2012
High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-beta family member growth differentiation factor 6.

Zhang L, Lim SL, Du H, Zhang M, Kozak I, Hannum G, Wang X, Ouyang H, Hughes G, Zhao L, Zhu X, Lee C, Su Z, Zhou X, Shaw R, Geum D, Wei X, Zhu J, Ideker T, Oka C, Wang N, Yang Z, Shaw PX, Zhang K

J Biol Chem. 2012 Jan 6;287(2):1520-6

University of California, San Diego - Senior Scientific Investigator Award - Zhang, Kang / MD, PhD Departmental Grant

Keywords: AMD, Gene Research/Therapy, Other: Genome-wide Association Study (GWAS

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