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Research to Prevent Blindness

2015 New Research - December

Browse or search other Recent Research.

Angiopoietin-like 4 as an Emerging Therapeutic Target for Diabetic Eye Disease

Sodhi A, Montaner S.
JAMA Ophthalmol.2015;133(12):1375-1376

Arrestin 1 and Cone Arrestin 4 have Unique Roles in Visual Function in an All-Cone Mouse Retina

Janise D. Deming, Joseph S. Pak, Jung-a Shin, Bruce M. Brown, Moon K. Kim, Moe H. Aung, Eun-Jin Lee, Machelle T. Pardue, Cheryl Mae Craft
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7618-7628

Cobalamin C Deficiency Shows a Rapidly Progressing Maculopathy with Severe Photoreceptor and Ganglion Cell Loss

Lucas Bonafede, Can H. Ficicioglu, Leona Serrano, Grace Han, Jessica I. W. Morgan, Monte D. Mills, Brian J. Forbes, Stefanie L. Davidson, Gil Binenbaum, Paige B. Kaplan, Charles W. Nichols, Patrick Verloo, Bart P. Leroy, Albert M. Maguire, Tomas S. Aleman
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7875-7887

Comparative Proteomic Analysis of Two Uveitis Models in Lewis Rats

Kathryn L. Pepple, Lauren Rotkis, Leslie Wilson, Angela Sandt, Russell N. Van Gelder
Invest. Ophthalmol. Vis. Sci. 2015;56(13):8449-8456

Corneal Expression of SLURP-1 by Age, Sex, Genetic Strain, and Ocular Surface Health

Sudha Swamynathan, Emili E. Delp, Stephen A. K. Harvey, Chelsea L. Loughner, Leela Raju, Shivalingappa K. Swamynathan
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7888-7896

Correlation of Severity of Fuchs Endothelial Corneal Dystrophy with Triplet Repeat Expansion in TCF4 

Soliman AZ, Xing C, Radwan SH, Gong X, Mootha V.
JAMA Ophthalmol 2015;133(12):1386-1391

Enface Thickness Mapping and Reflectance Imaging of Retinal Layers in Diabetic Retinopathy

Francis AW, Wanek J, Lim JI, Shahidi M 
PLoS ONE 10(12): e0145628

Evidence in Ophthalmology: Are We Doing Better?

Bojikian, Karine D. et al.
Ophthalmology, Volume 122, Issue 12, 2584 – 2586

Factors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial

Kempen, John H.Jaffe, Glenn J. et al.
American Journal of Ophthalmology, Volume 160, Issue 6, 1133 - 1141.e9

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration

Allison E. Songstad, Luke A. Wiley, Khahn Duong, Emily Kaalberg, Miles J. Flamme-Wiese, Cathryn M. Cranston, Megan J. Riker, Dana Levasseur, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker
Invest. Ophthalmol. Vis. Sci. 2015;56(13):8258-8267

High-Magnitude and/or High-Frequency Mechanical Strain Promotes Peripapillary Scleral Myofibroblast Differentiation

Jing Qu, Huaping Chen, Lanyan Zhu, Namasivayam Ambalavanan, Christopher A. Girkin, Joanne E. Murphy-Ullrich, J. Crawford Downs, Yong Zhou
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7821-7830

Hyperosmolar Tears Induce Functional and Structural Alterations of Corneal Nerves: Electrophysiological and Anatomical Evidence toward Neurotoxicity

Harumitsu Hirata, Kamila Mizerska, Carl F. Marfurt, Mark I. Rosenblatt
Invest. Ophthalmol. Vis. Sci. 2015;56(13):8125-8140

Induction of Neuronal Morphology in the 661W Cone Photoreceptor Cell Line with Staurosporine

Thompson AF, Crowe ME, Lieven CJ, Levin LA.
PLoS ONE 10(12): e0145270

Keratoplasty in the United States

Park, Choul Yong et al.
Ophthalmology, Volume 122, Issue 12, 2432 – 2442

Lens Position Parameters as Predictors of Intraocular Pressure Reduction after Cataract Surgery in Nonglaucomatous Patients with Open Angles

Chi-Hsin Hsu, Caitlin L. Kakigi, Shuai-Chun Lin, Yuan-Hung Wang, Travis Porco, Shan C. Lin
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7807-7813

Light-Regulated Thyroid Hormone Signaling Is Required for Rod Photoreceptor Development in the Mouse Retina

Onkar Sawant, Amanda M. Horton, Meenal Shukla, Mary E. Rayborn, Neal S. Peachey, Joe G. Hollyfield, Sujata Rao
Invest. Ophthalmol. Vis. Sci. 2015;56(13):8248-8257

Location of Initial Visual Field Defects in Glaucoma and Their Modes of Deterioration

Joon Mo Kim, Haksu Kyung, Seong Hee Shim, Parham Azarbod, Joseph Caprioli
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7956-7962

Measuring In Vivo Free Radical Production by the Outer Retina

Bruce A. Berkowitz, Bryce X. Bredell, Christopher Davis, Marijana Samardzija, Christian Grimm, Robin Roberts
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7931-7938

MicroRNA Expression in the Glaucomatous Retina

Hari Jayaram, William O. Cepurna, Elaine C. Johnson, John C. Morrison
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7971-7982

Ocular Safety of Intravitreal Propranolol and Its Efficacy in Attenuation of Choroidal Neovascularization

Ramin Nourinia, Mozhgan Rezaei Kanavi, Amir Kaharkaboudi, Seyed Iman Taghavi, Seyed Javid Aldavood, Soesiawati R. Darjatmoko, Shoujian Wang, Zafer Gurel, Jeremy A. Lavine, Sare Safi, Hamid Ahmadieh, Narsis Daftarian, Nader Sheibani
Invest. Ophthalmol. Vis. Sci. 2015;56(13):8228-8235

Physical Factors Affecting Outflow Facility Measurements in Mice

Alexandra Boussommier-Calleja, Guorong Li, Amanda Wilson, Tal Ziskind, Oana Elena Scinteie, Nicole E. Ashpole, Joseph M. Sherwood, Sina Farsiu, Pratap Challa, Pedro Gonzalez, J. Crawford Downs, C. Ross Ethier, W. Daniel Stamer, Darryl R. Overby
Invest. Ophthalmol. Vis. Sci. 2015;56(13):8331-8339

Primed Mycobacterial Uveitis (PMU): Histologic and Cytokine Characterization of a Model of Uveitis in Rats

Kathryn L. Pepple, Lauren Rotkis, Jennifer Van Grol, Leslie Wilson, Angela Sandt, Deborah L. Lam, Eric Carlson, Russell N. Van Gelder
Invest. Ophthalmol. Vis. Sci. 2015;56(13):8438-8448

Qualifying to Use a Home Monitoring Device for Detection of Neovascular Age-Related Macular Degeneration

Thomas M, Wolfson Y, Zayit-Soudry S, Bressler SB, Bressler NM.
JAMA Ophthalmol.2015;133(12):1425-1430

Retinal Architecture in RGS9 - and R9AP- Associated Retinal Dysfunction (Bradyopsia)

Strauss, Rupert W. et al.
American Journal of Ophthalmology, Volume 160, Issue 6, 1269 - 1275.e1

Simulation Surgical Teaching in Ophthalmology

McCannel, Colin A.
Ophthalmology, Volume 122, Issue 12, 2371 – 2372

Subconjunctivally Implanted Hydrogels for Sustained Insulin Release to Reduce Retinal Cell Apoptosis in Diabetic Rats

Hisanori Imai, Gauri P. Misra, Linfeng Wu, Dileep R. Janagam, Thomas W. Gardner, Tao L. Lowe Invest. Ophthalmol. Vis. Sci. 2015;56(13):7839-7846

Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma

Berry RH, Qu J, John SWM, Howell GR, Jakobs TC.
PLoS ONE 10(12):e0144341

Tear Production after Bilateral Main Lacrimal Gland Resection in Rabbits

Dhruva Bhattacharya, Yuan Ning, Fangkun Zhao, William Stevenson, Rongji Chen, Jinsong Zhang, Mingwu Wang
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7774-7783

Ten-Year Follow-up of a Blind Patient Chronically Implanted with Epiretinal Prosthesis Argus I

Yue, Lan et al.
Ophthalmology, Volume 122, Issue 12, 2545 - 2552.e1

The Connective Tissue Components of Optic Nerve Head Cupping in Monkey Experimental Glaucoma Part 1: Global Change

Hongli Yang, Ruojin Ren, Howard Lockwood, Galen Williams, Vincent Libertiaux, Crawford Downs, Stuart K. Gardiner, Claude F. Burgoyne
Invest. Ophthalmol. Vis. Sci. 2015;56(13):7661-7678

Thinner Retinal Nerve Fiber Layer in Very Preterm Versus Term Infants and Relationship to Brain Anatomy and Neurodevelopment

Rothman, Adam L. et al.
American Journal of Ophthalmology, Volume 160, Issue 6, 1296 - 1308.e2

Thrombomodulin Protects Against Bacterial Keratitis, Is Anti-Inflammatory, but Not Angiogenic

Sharon A. McClellan, Sandamali A. Ekanayaka, Cui Li, Xiaoyu Jiang, Ronald P. Barrett, Linda D. Hazlett Invest. Ophthalmol. Vis. Sci. 2015;56(13):8091-8100

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