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Research to Prevent Blindness

Research Database

University of North Carolina Research, funded by RPB from 2010-2014 matching Departmental Grant

124 Citations, Sorted by Month and Year

November, 2014
Instrument development of the UNC dry eye management scale.

Grubbs J,Jr, Huynh K, Tolleson-Rinehart S, Weaver MA, Williamson J, Lefebvre C, Davis RM

Cornea. 2014 Nov;33(11):1186-92.

University of North Carolina - Departmental Grant

Keywords: Dry Eye, Epidemiology

October, 2014
Diagnostic specificities of retinal nerve fiber layer, optic nerve head, and macular ganglion cell-inner plexiform layer measurements in myopic eyes.

Aref AA, Sayyad FE, Mwanza JC, Feuer WJ, Budenz DL

J Glaucoma. 2014 Oct-Nov;23(8):487-93.

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma.

Bailey JN, Yaspan BL, Pasquale LR, Hauser MA, Kang JH, Loomis SJ, Brilliant M, Budenz DL, Christen WG, Fingert J, Gaasterland D, Gaasterland T, Kraft P, Lee RK, Lichter PR, Liu Y, McCarty CA, Moroi SE, Richards JE, Realini T, Schuman JS, Scott WK, Singh K, Sit AJ, Vollrath D, Wollstein G, Zack DJ, Zhang K, Pericak-Vance MA, Allingham RR, Weinreb RN, Haines JL, Wiggs JL

Hum Genet. 2014 Oct;133(10):1319-30.

University of North Carolina - Departmental Grant

Keyword: Glaucoma

The cellular and molecular biology of the iris, an overlooked tissue: The iris and pseudoexfoliation glaucoma.

Borras T

J Glaucoma. 2014 Oct-Nov:S39-42.

University of North Carolina - Departmental Grant

Keyword: Glaucoma

September, 2014
An Improved Temporary Keratoprosthesis.

Park H, Fayyad F, Landers M

Retina Today. 2014 Sep;42-44.

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

Cerebrospinal fluid pressure trends in diseases associated with primary open-angle glaucoma.

Fleischman D, Berdahl J, Stinnett SS, Fautsch MP, Allingham RR

Acta Ophthalmol. 2014 Sep 10

University of North Carolina - Departmental Grant

Keywords: Epidemiology, Glaucoma

Longitudinal changes in peripapillary atrophy in the ocular hypertension treatment study: A case-control assessment.

Savatovsky E, Mwanza JC, Budenz DL, Feuer WJ, Vandenbroucke R, Schiffman JC, Anderson DR, Ocular Hypertension Treatment Study

Ophthalmology. 2014 Sep 7

University of North Carolina - Departmental Grant

Keywords: Epidemiology, Glaucoma

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.

Springelkamp H, Hohn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, Xu L, Mountain JE, Gharahkhani P, Lu Y, Amin N, Karssen LC, Sim KS, van Leeuwen EM, Iglesias AI, Verhoeven VJ, Hauser MA, Loon SC, Despriet DD, Nag A, Venturini C, Sanfilippo PG, Schillert A, Kang JH, Landers J, Jonasson F, Cree AJ, van Koolwijk LM, Rivadeneira F, Souzeau E, Jonsson V, Menon G, Blue Mountains Eye Study-GWAS group, Weinreb RN, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A, Ennis S, Thorsteinsdottir U, Burdon KP, NEIGHBORHOOD Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), Spector TD, Mirshahi A, Saw SM, Vingerling JR, Teo YY, Haines JL, Wolfs RC, Lemij HG, Tai ES, Jansonius NM, Jonas JB, Cheng CY, Aung T, Viswanathan AC, Klaver CC, Craig JE, Macgregor S, Mackey DA, Lotery AJ, Stefansson K, Bergen AA, Young TL, Wiggs JL, Pfeiffer N, Wong TY, Pasquale LR, Hewitt AW, van Duijn CM, Hammond CJ, Blue Mountains Eye Study-GWAS group, NEIGHBORHOOD Consortium, Wellcome Trust Case Control Consortium 2 WTCCC2

Nat Commun. 2014 Sep 22;5:4883.

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Serum 8,12-iso-iPF2alpha-VI isoprostane marker of oxidative damage and cognition deficits in children with konzo.

Makila-Mabe BG, Kikandau KJ, Sombo TM, Okitundu DL, Mwanza JC, Boivin MJ, Ngoyi MD, Muyembe JJ, Banea JP, Boss GR, Tshala-Katumbay D

PLoS One. 2014 Sep 15;9(9):e107191.

University of North Carolina - Departmental Grant

Keywords: Epidemiology, Pediatric

Sub-tenon triamcinolone acetonide injections for topical medication intolerance in chronic blepharokeratoconjunctivitis.

Bondalapati S, Cabrera MT

Cornea. 2014 Sep;33(9):999-1001.

University of North Carolina - Departmental Grant

Keyword: Cornea

August, 2014
Three-year treatment outcomes in the ahmed baerveldt comparison study.

Barton K, Feuer WJ, Budenz DL, Schiffman J, Costa VP, Godfrey DG, Buys YM, Ahmed Baerveldt Comparison Study Group

Ophthalmology. 2014 Aug;121(8):1547,57.e1.

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Vitreous humor thermodynamics during phacoemulsification.

Salcedo-Villanueva G, Kon-Jara V, Harasawa M, Cervantes-Coste G, Ochoa-Contreras D, Morales-Canton V, Guerrero-Naranjo JL, Quiroz-Mercado H, Landers MB,3rd

Int Ophthalmol. 2014 Aug 7

University of North Carolina - Departmental Grant

Keywords: Cataract, Retina/Retinal Diseases

July, 2014
Evidence of early ultrastructural photoreceptor abnormalities in light-induced retinal degeneration using spectral domain optical coherence tomography.

Aziz MK, Ni A, Esserman DA, Chavala SH

Br J Ophthalmol. 2014 Jul;98(7):984-9.

University of North Carolina - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Sporadic visual acuity loss in the comparison of age-related macular degeneration treatments trials (CATT).

Kim BJ, Ying GS, Huang J, Levy NE, Maguire MG, CATT Research Group

Am J Ophthalmol. 2014 Jul;158(1):128,135.e10.

University of North Carolina - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

June, 2014
The prevalence and incidence of epiretinal membranes in eyes with inactive extramacular CMV retinitis.

Kozak I, Vaidya V, Van Natta ML, Pak JW, May KP, Thorne JE, Studies of the Ocular Complications of AIDS Research Group

Invest Ophthalmol Vis Sci. 2014 Jun 12;55(7):4304-12.

University of North Carolina - Departmental Grant

Keywords: Epidemiology, Retina/Retinal Diseases, Uveitis/Infectious Diseases

Thyroid eye disease: Therapy in the active phase.

Bhatti MT, Dutton JJ

J Neuroophthalmol. 2014 Jun;34(2):186-97.

University of North Carolina - Departmental Grant

Keyword: Thyroid Ophthalmology

Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma.

Kang JH, Loomis SJ, Yaspan BL, Bailey JC, Weinreb RN, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Gaasterland D, Gaasterland T, Friedman DS, McCarty CA, Moroi SE, Olson L, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Brilliant M, Sit AJ, Christen WG, Fingert J, Forman JP, Buys ES, Kraft P, Zhang K, Allingham RR, Pericak-Vance MA, Richards JE, Hauser MA, Haines JL, Wiggs JL, Pasquale LR

Eye (Lond). 2014 Jun;28(6):662-71.

University of North Carolina - Departmental Grant

Keyword: Glaucoma

May, 2014
Tissue necrosis following diode laser-assisted transcanalicular dacryocystorhinostomy.

McClintic SM, Yoon MK, Bidar M, Dutton JJ, Vagefi MR, Kersten RC

Ophthal Plast Reconstr Surg. 2014 May 6

University of North Carolina - Departmental Grant

Keyword: Oculoplastic

Uveal melanoma treated with iodine-125 episcleral plaque: An analysis of dose on disease control and visual outcomes.

Perez BA, Mettu P, Vajzovic L, Rivera D, Alkaissi A, Steffey BA, Cai J, Stinnett S, Dutton JJ, Buckley EG, Halperin E, Marks LB, Mruthyunjaya P, Kirsch DG

Int J Radiat Oncol Biol Phys. 2014 May 1;89(1):127-36.

University of North Carolina - Departmental Grant

Keyword: Ocular Oncology/Pterygium

VEGFA and VEGFR2 gene polymorphisms and response to anti-vascular endothelial growth factor therapy: Comparison of age-related macular degeneration treatments trials (CATT).

Hagstrom SA, Ying GS, Pauer GJ, Sturgill-Short GM, Huang J, Maguire MG, Martin DF, Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Research Group

JAMA Ophthalmol. 2014 May;132(5):521-7.

University of North Carolina - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

April, 2014
Combining frequency doubling technology perimetry and scanning laser polarimetry for glaucoma detection.

Mwanza JC, Warren JL, Hochberg JT, Budenz DL, Chang RT, Ramulu PY

J Glaucoma. 2014 Apr 25

University of North Carolina - Departmental Grant

Keywords: Glaucoma, Imaging

Determinants of self-reported barriers to glaucoma medicine administration and adherence: A multisite study.

Sleath BL, Blalock SJ, Muir KW, Carpenter DM, Lawrence SD, Giangiacomo AL, Goldsmith JA, Hartnett ME, Slota C, Robin AL

Ann Pharmacother. 2014 Apr 1;48(7):856-62.

University of North Carolina - Departmental Grant

Keywords: Epidemiology, Glaucoma

Diagnostic performance of optical coherence tomography ganglion cell-inner plexiform layer thickness measurements in early glaucoma.

Mwanza JC, Budenz DL, Godfrey DG, Neelakantan A, Sayyad FE, Chang RT, Lee RK

Ophthalmology. 2014 Apr;121(4):849-54.

University of North Carolina - Departmental Grant

Keywords: Glaucoma, Imaging

March, 2014
An eye for the eye: Seeing art in medicine.

Huynh K, Grubbs J,Jr, Davis RM

J Gen Intern Med. 2014 Mar;29(3):547-8.

University of North Carolina - Departmental Grant

Keyword: Other: Graphic Arts

Chronic, recurrent dacryocystitis from a BB in the lacrimal sac.

Lee LB, Dutton JJ

Ophthal Plast Reconstr Surg. 2014 Mar-Apr;30(2):e40-1.

University of North Carolina - Departmental Grant

Keyword: Oculoplastic

Hemorrhagic unilateral retinopathy.

Kon Graversen VA, Jampol LM, Meredith T, Landers M,3rd, Slakter J, Brucker AJ, Rabb M

Retina. 2014 Mar;34(3):483-9.

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

New options for combined cataract and glaucoma surgery.

Budenz DL, Gedde SJ

Curr Opin Ophthalmol. 2014 Mar;25(2):141-7.

University of North Carolina - Departmental Grant

Keywords: Cataract, Glaucoma

Perceptions of dry eye disease management in current clinical practice.

Williamson JF, Huynh K, Weaver MA, Davis RM

Eye Contact Lens. 2014 Mar;40(2):111-5.

University of North Carolina - Departmental Grant

Keyword: Dry Eye

Sustained drug delivery in glaucoma.

Knight OJ, Lawrence SD

Curr Opin Ophthalmol. 2014 Mar;25(2):112-7.

University of North Carolina - Departmental Grant

Keywords: Glaucoma, Nanotechnology/Drug Delivery

The effects of myocilin expression on functionally relevant trabecular meshwork genes: A mini-review.

Borras T

J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):202-12.

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Topical nepafenac after intravitreal injection: A prospective double-masked randomized controlled trial.

Ulrich JN

Retina. 2014 Mar;34(3):509-11.

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

February, 2014
A review of quality of life measures in dry eye questionnaires.

Grubbs JR,Jr, Tolleson-Rinehart S, Huynh K, Davis RM

Cornea. 2014 Feb;33(2):215-8.

University of North Carolina - Departmental Grant

Keywords: Dry Eye, Epidemiology

Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss.

Loomis SJ, Kang JH, Weinreb RN, Yaspan BL, Cooke Bailey JN, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, McCarty CA, Moroi SE, Olson L, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Brilliant M, Sit AJ, Christen WG, Fingert J, Kraft P, Zhang K, Allingham RR, Pericak-Vance MA, Richards JE, Hauser MA, Haines JL, Pasquale LR, Wiggs JL

Ophthalmology. 2014 Feb;121(2):508-16.

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

K137R mutation on adeno-associated viral capsids had minimal effect on enhancing gene delivery in vivo.

Qiao C, Li C, Zhao C, Li J, Bian T, Grieger J, Li J, Samulski RJ, Xiao X

Hum Gene Ther Methods. 2014 Feb;25(1):33-9.

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Normative values and predictors of retinal oxygen saturation.

Jani PD, Mwanza JC, Billow KB, Waters AM, Moyer S, Garg S

Retina. 2014 Feb;34(2):394-401.

University of North Carolina - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

January, 2014
AAV-mediated gene editing via double-strand break repair.

Hirsch ML, Samulski RJ

Methods Mol Biol. 2014;1114:291-307.

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Autoimmunity in the pathogenesis and treatment of keratoconjunctivitis sicca.

Liu KC, Huynh K, Grubbs J,Jr, Davis RM

Curr Allergy Asthma Rep. 2014 Jan;14(1):403,013-0403-7.

University of North Carolina - Departmental Grant

Keywords: Cornea, Epidemiology

Posterior scleral biomechanics and the translaminar pressure difference.

Fleischman D, Berdahl JP

Int Ophthalmol Clin. 2014 Winter;54(1):73-94.

University of North Carolina - Departmental Grant

Keywords: Glaucoma, Other: Sclera

Promyelocytic leukemia protein is a cell-intrinsic factor inhibiting parvovirus DNA replication.

Mitchell AM, Hirsch ML, Li C, Samulski RJ

J Virol. 2014 Jan;88(2):925-36.

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

December, 2013
Combining spectral domain optical coherence tomography structural parameters for the diagnosis of glaucoma with early visual field loss.

Mwanza J, Warren JL, Budenz DL

Invest Ophthalmol Vis Sci. 2013 Dec 30;54(13):8393-400

University of North Carolina - Departmental Grant

Keywords: Glaucoma, Imaging

Oversized AAV transductifon is mediated via a DNA-PKcs-independent, Rad51C-dependent repair pathway.

Hirsch ML, Li C, Bellon I, Yin C, Chavala S, Pryadkina M, Richard I, Samulski RJ

Mol Ther. 2013 Dec;21(12):2205-16

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

November, 2013
Retinal arteriolar tortuosity and artery occlusion.

Chavala SH, Williamson JF

Lancet. 2013 Nov 16;382(9905):1655

University of North Carolina - Career Development Award - Chavala, Sai H / MD Departmental Grant

Keyword: Retinal Vein and Artery Occlusion

October, 2013
Increasing intraocular pressure as treatment for papilledema.

Fleischman D, Berdahl JP, Fautsch MP, Chesnutt DA, Allingham RR

Exp Eye Res. 2013 Oct;115:278

University of North Carolina - Departmental Grant

Keyword: Other: Papilledema

Racial variation in optic nerve head parameters quantified in healthy newborns by handheld spectral domain optical coherence tomography.

Allingham MJ, Cabrera MT, O'Connell RV, Maldonado RS, Tran-Viet D, Toth CA, Freedman SF, El-Dairi MA

J AAPOS. 2013 Oct;17(5):501-6

University of North Carolina - Departmental Grant

Keywords: Imaging, Pediatric

Retinal angiogenesis suppression through small molecule activation of p53.

Chavala SH, Kim Y, Tudisco L, Cicatiello V, Milde T, Kerur N, Claros N, Yanni S, Guaiquil VH, Hauswirth WW, Penn JS, Rafii S, De Falco S, Lee TC, Ambati J

J Clin Invest. 2013 Oct 1;123(10):4170-81

University of North Carolina - Career Development Award - Chavala, Sai H / MD Departmental Grant

Keywords: Retina/Retinal Diseases, Stem Cell Research/Therapy

The impact of surgical intraocular pressure reduction on visual function using various criteria to define visual field progression.

Bhardwaj N, Niles PI, Greenfield DS, Hymowitz M, Sehi M, Feuer WJ, Budenz DL

J Glaucoma. 2013 Oct-Nov;22(8):632-7

University of North Carolina - Departmental Grant

Keyword: Glaucoma

September, 2013
Facile and efficient reprogramming of ciliary body epithelial cells into induced pluripotent stem cells.

Ni A, Wu MJ, Nakanishi Y, Chavala SH

Stem Cells Dev. 2013 Sep 15;22(18):2543-50

University of North Carolina - Career Development Award - Chavala, Sai H / MD Departmental Grant

Keyword: Stem Cell Research/Therapy

Institutional review boards, declaration of helsinki, and HIPAA regulations.

Dutton JJ

Ophthal Plast Reconstr Surg. 2013 Sep;29(5):335-40

University of North Carolina - Departmental Grant

Keyword: Other: Ethics

Investigation of known genetic risk factors for primary open angle glaucoma in two populations of african ancestry.

Liu Y, Hauser MA, Akafo SK, Qin X, Miura S, Gibson JR, Wheeler J, Gaasterland DE, Challa P, Herndon LW, International Consortium of African Ancestry REsearch in Glaucoma, Ritch R, Moroi SE, Pasquale LR, Girkin CA, Budenz DL, Wiggs JL, Richards JE, Ashley-Koch AE, Allingham RR

Invest Ophthalmol Vis Sci. 2013 Sep 17;54(9):6248-54

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Macular findings in healthy full-term hispanic newborns observed by hand-held spectral-domain optical coherence tomography.

Cabrera MT, O'Connell RV, Toth CA, Maldonado RS, Tran-Viet D, Allingham MJ, Chiu SJ, Farsiu S, Maradiaga Panayotti GM, Swamy GK, Freedman SF

Ophthalmic Surg Lasers Imaging Retina. 2013 Sep-Oct;44(5):448-54

University of North Carolina - Departmental Grant

Keywords: Imaging, Pediatric

Perineural optic nerve enhancement on magnetic resonance imaging in giant cell arteritis.

Liu KC, Chesnutt DA

J Neuroophthalmol. 2013 Sep;33(3):279-81

University of North Carolina - Departmental Grant

Keywords: Imaging, Neuro-Ophthalmology

Peripheral retinal nonperfusion in fellow eyes in coats disease.

Blair MP, Ulrich JN, Elizabeth Hartnett M, Shapiro MJ

Retina. 2013 Sep;33(8):1694-9

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

Solitary fibrous tumor of the orbit with multiple cavities.

Polomsky M, Sines DT, Dutton JJ

Ophthal Plast Reconstr Surg. 2013 Sep;29(5):e117-9

University of North Carolina - Departmental Grant

Keyword: Plastic Surgery

The NEIGHBOR consortium primary open-angle glaucoma genome-wide association study: Rationale, study design, and clinical variables.

Wiggs JL, Hauser MA, Abdrabou W, Allingham RR, Budenz DL, Delbono E, Friedman DS, Kang JH, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Loomis S, Liu Y, McCarty C, Medeiros FA, Moroi SE, Olson LM, Realini A, Richards JE, Rozsa FW, Schuman JS, Singh K, Stein JD, Vollrath D, Weinreb RN, Wollstein G, Yaspan BL, Yoneyama S, Zack D, Zhang K, Pericak-Vance M, Pasquale LR, Haines JL

J Glaucoma. 2013 Sep;22(7):517-25

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

August, 2013
Aqueous shunt exposure: A retrospective review of repair outcome.

Huddleston SM, Feldman RM, Budenz DL, Bell NP, Lee DA, Chuang AZ, Mankiewicz KA, Koval MS, Truong E, Moraczewski A

J Glaucoma. 2013 Aug;22(6):433-8

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Development of a model of elevated intraocular pressure in rats by gene transfer of bone morphogenetic protein 2.

Buie LK, Karim MZ, Smith MH, Borras T

Invest Ophthalmol Vis Sci. 2013 Aug 13;54(8):5441-55

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Effect of pupil dilation on macular choroidal thickness measured with spectral domain optical coherence tomography in normal and glaucomatous eyes.

Mwanza JC, Sayyad FE, Banitt MR, Budenz DL

Int Ophthalmol. 2013 Aug;33(4):335-41

University of North Carolina - Departmental Grant

Keywords: Glaucoma, Imaging

Effect of radiation therapy on intraocular pressure in patients with graves' orbitopathy.

Russell DJ, Dutton JJ, Baca RL

Orbit. 2013 Aug;32(4):219-24

University of North Carolina - Departmental Grant

Keyword: Thyroid Ophthalmology

External beam radiotherapy for head and neck cancers is associated with increased variability in retinal vascular oxygenation.

Higginson DS, Sahgal A, Lawrence MV, Moyer S, Stefanescu M, Willson AK, Qaqish B, Zanation A, Marks LB, Garg S, Chera BS

PLoS One. 2013 Aug 6;8(8):e69657

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

Tissue plasminogen activator in trabecular meshwork attenuates steroid induced outflow resistance in mice.

Kumar S, Shah S, Tang HM, Smith M, Borras T, Danias J

PLoS One. 2013 Aug 19;8(8):e72447

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

July, 2013
Bilateral exudative retinal detachments in sturge-weber syndrome.

Chavala SH, Williamson JF

Lancet. 2013 Jul 20;382(9888):259

University of North Carolina - Career Development Award - Chavala, Sai H / MD Departmental Grant

Keyword: Retina/Retinal Diseases

Estrogen pathway polymorphisms in relation to primary open angle glaucoma: An analysis accounting for gender from the united states.

Pasquale LR, Loomis SJ, Weinreb RN, Kang JH, Yaspan BL, Bailey JC, Gaasterland D, Gaasterland T, Lee RK, Scott WK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, McCarty CA, Moroi SE, Olson L, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Brilliant M, Sit AJ, Christen WG, Fingert J, Kraft P, Zhang K, Allingham RR, Pericak-Vance MA, Richards JE, Hauser MA, Haines JL, Wiggs JL

Mol Vis. 2013 Jul 12;19:1471-81

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Focal choroidal excavation associated with polypoidal choroidal vasculopathy.

Say EA, Jani PD, Appenzeller MF, Houghton OM

Ophthalmic Surg Lasers Imaging Retina. 2013 Jul-Aug;44(4):409-11

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

Immediate hyphema after intravitreal injections of ranibizumab.

Kon GV, Meredith T, Landers M, Garg S

Retinal Cases and Brief Reports. 2013 Summer;7(3):242-4

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

Pars plana vitrectomy for rhegmatogenous retinal detachment associated with benign retinal tumors.

Say EA, Jani PD, Ulrich JN

Ophthalmic Surg Lasers Imaging Retina. 2013 Jul-Aug;44(4):412-4

University of North Carolina - Departmental Grant

Keyword: Retinal Detachment

June, 2013
Choroid development and feasibility of choroidal imaging in the preterm and term infants utilizing SD-OCT.

Moreno TA, O'Connell RV, Chiu SJ, Farsiu S, Cabrera MT, Maldonado RS, Tran-Viet D, Freedman SF, Wallace DK, Toth CA

Invest Ophthalmol Vis Sci. 2013 Jun 14;54(6):4140-7

University of North Carolina - Departmental Grant

Keywords: Imaging, Pediatric

Gamma-irradiated cornea allograft for glaucoma surgery.

Lawrence SD, Netland PA

J Glaucoma. 2013 Jun-Jul;22(5):355-7

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Ptosis, erythema, and rapidly decreasing vision.

Zanation A, Fleischman D, Chavala SH

JAMA. 2013 Jun 12;309(22):2382-3

University of North Carolina - Career Development Award - Chavala, Sai H / MD Departmental Grant

Keyword: Plastic Surgery

May, 2013
Age-related changes in the pediatric human orbit on CT.

Escaravage GK,Jr, Dutton JJ

Ophthal Plast Reconstr Surg. 2013 May-Jun;29(3):150-6

University of North Carolina - Departmental Grant

Keywords: Imaging, Pediatric

APRONES: Neurology research and education in the democratic republic of the congo.

Luabeya MK, Mwanza JC, Mukendi KM, Tshala-Katumbay D

Neurology. 2013 May 7;80(19):1806-7

University of North Carolina - Departmental Grant

Keyword: Other: Neurology

Gene therapy and neurodevelopmental disorders.

Gray SJ

Neuropharmacology. 2013 May;68:136-42

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Kinetics of adeno-associated virus serotype 2 (AAV2) and AAV8 capsid antigen presentation in vivo are identical.

He Y, Weinberg MS, Hirsch M, Johnson MC, Tisch R, Samulski RJ, Li C

Hum Gene Ther. 2013 May;24(5):545-53

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Prevalence of glaucoma in an urban west african population: The tema eye survey.

Budenz DL, Barton K, Whiteside-de Vos J, Schiffman J, Bandi J, Nolan W, Herndon L, Kim H, Hay-Smith G, Tielsch JM, Tema Eye Survey Study Group

JAMA Ophthalmol. 2013 May;131(5):651-8

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Progress in gene therapy for neurological disorders.

Simonato M, Bennett J, Boulis NM, Castro MG, Fink DJ, Goins WF, Gray SJ, Lowenstein PR, Vandenberghe LH, Wilson TJ, Wolfe JH, Glorioso JC

Nat Rev Neurol. 2013 May;9(5):277-91

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

April, 2013
Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates.

Gray SJ, Nagabhushan Kalburgi S, McCown TJ, Jude Samulski R

Gene Ther. 2013 Apr;20(4):450-9

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Ocular disease, knowledge and technology applications in patients with diabetes.

Threatt J, Williamson JF, Huynh K, Davis RM

Am J Med Sci. 2013 Apr;345(4):266-70

University of North Carolina - Departmental Grant

Keyword: Diabetic Retinopathy

The role of cerebrospinal fluid pressure in glaucoma and other ophthalmic diseases: A review.

Fleischman D, Allingham RR

Saudi J Ophthalmol. 2013 Apr;27(2):97-106

University of North Carolina - Departmental Grant

Keyword: Glaucoma

March, 2013
Adeno-associated virus capsid antigen presentation is dependent on endosomal escape.

Li C, He Y, Nicolson S, Hirsch M, Weinberg MS, Zhang P, Kafri T, Samulski RJ

J Clin Invest. 2013 Mar 1;123(3):1390-401

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype.

Ellis BL, Hirsch ML, Barker JC, Connelly JP, Steininger RJ,3rd, Porteus MH

Virol J. 2013 Mar 6;10:74

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Dematiaceous fungi mimicking a conjunctival melanoma.

Moss HB, Fowler WC, Schell WA, Perfect JR, Zedek DC

Ophthal Plast Reconstr Surg. 2013 Mar-Apr;29(2):e65-6

University of North Carolina - Departmental Grant

Keyword: Cornea

Do all candidemic patients need an ophthalmic examination?

Vinikoor MJ, Zoghby J, Cohen KL, Tucker JD

Int J Infect Dis. 2013 Mar;17(3):e146-8

University of North Carolina - Departmental Grant

Keyword: Cornea

February, 2013
Optimization of scAAVIL-1ra in vitro and in vivo to deliver high levels of therapeutic protein for treatment of osteoarthritis.

Goodrich LR, Phillips JN, McIlwraith CW, Foti SB, Grieger JC, Gray SJ, Samulski RJ

Mol Ther Nucleic Acids. 2013 Feb 5;2:e70

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Recent gene therapy advancements for neurological diseases.

Nagabhushan Kalburgi S, Khan NN, Gray SJ

Discov Med. 2013 Feb;15(81):111-9

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Restoration of cytoskeleton homeostasis after gigaxonin gene transfer for giant axonal neuropathy.

Mussche S, Devreese B, Nagabhushan Kalburgi S, Bachaboina L, Fox JC, Shih HJ, Van Coster R, Samulski RJ, Gray SJ

Hum Gene Ther. 2013 Feb;24(2):209-19

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

January, 2013
Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice.

Gadalla KK, Bailey ME, Spike RC, Ross PD, Woodard KT, Kalburgi SN, Bachaboina L, Deng JV, West AE, Samulski RJ, Gray SJ, Cobb SR

Mol Ther. 2013 Jan;21(1):18-30

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

In cellulo examination of a beta-alpha hybrid construct of beta-hexosaminidase A subunits, reported to interact with the GM2 activator protein and hydrolyze GM2 ganglioside.

Sinici I, Yonekawa S, Tkachyova I, Gray SJ, Samulski RJ, Wakarchuk W, Mark BL, Mahuran DJ

PLoS One. 2013;8(3):e57908

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

Molecular biomarkers in glaucoma.

Bhattacharya SK, Lee RK, Grus FH, Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):121-31

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Oversized AAV transductifon is mediated via a DNA-PKcs-independent, Rad51C-dependent repair pathway.

Matthew LH, Li C, Bellon I, Yin C, Chavala S, Pryadkina M, Richard I, Richard JS

Mol Ther. 2013;21(12):2205-16

University of North Carolina - Departmental Grant

Keyword: Gene Research/Therapy

December, 2012
Cerebrospinal fluid pressure decreases with older age.

Fleischman D, Berdahl JP, Zaydlarova J, Stinnett S, Fautsch MP, Allingham RR

PLoS One. 2012 Dec 26;7(12):e52664

University of North Carolina - Departmental Grant

Keyword: Glaucoma

November, 2012
Rates of abnormal retinal nerve fiber layer and ganglion cell layer OCT scans in healthy myopic eyes: Cirrus versus RTVue.

Mwanza J, Sayyad F, Aref A, Budenz D

Ophthalmic Surg Lasers Imaging. 2012 Nov/Dec;43(6):S67-74

University of North Carolina - Departmental Grant

Keyword: Imaging

Telemedicine and retinal imaging for improving diabetic retinopathy evaluation.

Garg S, Jani P, Kshirsagar A, King B, Chaum E

Arch Intern Med. 2012 Nov 26;172(21):1677-80

University of North Carolina - Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

Trabeculectomy versus combined trabeculotomy-trabeculectomy in pediatric glaucoma.

Lawrence SD, Netland PA

J Pediatr Ophthalmol Strabismus. 2012 Nov/Dec;49(6):359-65

University of North Carolina - Departmental Grant

Keywords: Glaucoma, Pediatric

September, 2012
Choroidal thickness in unilateral advanced glaucoma.

Mwanza JC, Sayyad FE, Budenz DL

Invest Ophthalmol Vis Sci. 2012 Sep 28;53(10):6695-701

University of North Carolina - Departmental Grant

Keyword: Glaucoma

August, 2012
Multimodality diagnostic imaging in a case of sympathetic ophthalmia.

Fleischman D, Say EA, Wright JD, Landers MB

Ocul Immunol Inflamm. 2012 Aug;20(4):300-2

University of North Carolina - Departmental Grant

Keyword: Imaging

July, 2012
Epithelioid hemangioma responsive to oral propranolol.

Moss HB, Sines DT, Blatt J, Dutton JJ, Proia AD

Ophthal Plast Reconstr Surg. 2012 Jul-Aug;28(4):e88-90

University of North Carolina - Departmental Grant

Keyword: Plastic Surgery

June, 2012
Cholinesterase inhibition and depression of the photic after discharge of flash evoked potentials following acute or repeated exposures to a mixture of carbaryl and propoxur.

Mwanza JC, Lyke DF, Hertzberg RC, Haber L, Kohrman-Vincent M, Li R, Pan Y, Lyles RH, Simmons JE, Macmillan DK, Zehr RD, Swank AE, Herr DW

Neurotoxicology. 2012 Jun;33(3):332-46

University of North Carolina - Departmental Grant

Keyword: Other: Neurophysiology

Glaucoma diagnostic accuracy of ganglion cell-inner plexiform layer thickness: Comparison with nerve fiber layer and optic nerve head.

Mwanza JC, Durbin MK, Budenz DL, Sayyad FE, Chang RT, Neelakantan A, Godfrey DG, Carter R, Crandall AS

Ophthalmology. 2012 Jun;119(6):1151-8

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Metastatic B-cell lymphoma masquerading as infectious retinitis and vasculitis.

Say EA, Knupp CL, Gertsch KR, Chavala SH

Oncol Lett. 2012 Jun;3(6):1245-8

University of North Carolina - Departmental Grant

Keywords: Ocular Oncology/Pterygium, Retina/Retinal Diseases

May, 2012
Advances in glaucoma treatment and management: Gene therapy.

Borras T

Invest Ophthalmol Vis Sci. 2012 May 4;53(5):2506-10

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma.

Moss HB, Chavala S, Say E, Miller MB

J Clin Microbiol. 2012 May;50(5):1796-9

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

April, 2012
Automated segmentation of intraretinal cystoid fluid in optical coherence tomography.

Wilkins GR, Houghton OM, Oldenburg AL

IEEE Trans Biomed Eng. 2012 Apr;59(4):1109-14

University of North Carolina - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

March, 2012
Body mass index has a linear relationship with cerebrospinal fluid pressure.

Berdahl JP, Fleischman D, Zaydlarova J, Stinnett S, Allingham RR, Fautsch MP

Invest Ophthalmol Vis Sci. 2012 Mar 15;53(3):1422-7

University of North Carolina - Departmental Grant

Keyword: Neuro-Ophthalmology

What's new in laser treatment for glaucoma?

Meyer JJ, Lawrence SD

Curr Opin Ophthalmol. 2012 Mar;23(2):111-7

University of North Carolina - Departmental Grant

Keyword: Glaucoma

February, 2012
Exploratory dijkstra forest based automatic vessel segmentation: Applications in video indirect ophthalmoscopy (VIO).

Estrada R, Tomasi C, Cabrera MT, Wallace DK, Freedman SF, Farsiu S

Biomed Opt Express. 2012 Feb 1;3(2):327-39

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

January, 2012
Cystatin a, a potential common link for mutant myocilin causative glaucoma.

Kennedy KD, AnithaChristy SA, Buie LK, Borras T

PLoS One. 2012;7(5):e36301

University of North Carolina - Departmental Grant

Keyword: Glaucoma

Determination of retinal and vitreous temperature in vitrectomy.

Landers MB,3rd, Watson JS, Ulrich JN, Quiroz-Mercado H

Retina. 2012 Jan;32(1):172-6

University of North Carolina - Departmental Grant

Keyword: Retina/Retinal Diseases

Keratouveitis from euphorbia cyparissias exposure is a temporal phenomenon.

Fleischman D, Meyer JJ, Fowler WC

Clin Ophthalmol. 2012;6:851-3

University of North Carolina - Departmental Grant

Keyword: Uveitis/Infectious Diseases

Subfoveal fluid in healthy full-term newborns observed by handheld spectral-domain optical coherence tomography.

Cabrera MT, Maldonado RS, Toth CA, O'Connell RV, Chen BB, Chiu SJ, Farsiu S, Wallace DK, Stinnett SS, Panayotti GM, Swamy GK, Freedman SF

Am J Ophthalmol. 2012 Jan;153(1):167-75.e3

University of North Carolina - Departmental Grant

Keywords: Pediatric, Retina/Retinal Diseases

November, 2011
Lipoblastomatosis: Case report and review of the literature.

Dutton JJ, Escaravage GK,Jr, Fowler AM, Wright JD

Ophthal Plast Reconstr Surg. 2011 Nov;27(6):417-21

University of North Carolina - Departmental Grant

Keyword: Plastic Surgery

October, 2011
A health insurance portability and accountability act-compliant ocular telehealth network for the remote diagnosis and management of diabetic retinopathy.

Li Y, Karnowski TP, Tobin KW, Giancardo L, Morris S, Sparrow SE, Garg S, Fox K, Chaum E

Telemed J E Health. 2011 Oct;17(8):627-34

University of North Carolina - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Gene therapy strategies in glaucoma and application for steroid-induced hypertension.

Borrás T

Saudi Journal of Ophthalmology. 2011 Oct 1;25(4):353-62

University of North Carolina - Departmental Grant

Keyword: Glaucoma

August, 2011
The landers trunkless temporary keratoprosthesis.

Watson JS, Tran TT, Landers MB,3rd

Arch Ophthalmol. 2011 Aug;129(8):1067-9

University of North Carolina - Departmental Grant

Keyword: Artificial Vision

June, 2011
Maintaining a watertight globe while operating with a temporary keratoprosthesis.

Watson JS, Tran TT, Porfilio WL, Landers MB,3rd

Retina. 2011 Jun;31(6):1118-21

University of North Carolina - Departmental Grant

Keyword: Artificial Vision

OCT-documented incision features and natural history of clear corneal incisions used for bimanual microincision cataract surgery.

Lyles GW, Cohen KL, Lam D

Cornea. 2011 Jun;30(6):681-6

University of North Carolina - Departmental Grant

Keywords: Cataracts, Cornea

May, 2011
Bilateral spontaneous subperiosteal orbital hemorrhages following endoscopic retrograde cholangiopancreatography.

Russell DJ, Dutton JJ

Ophthal Plast Reconstr Surg. 2011 May-Jun;27(3):e49-50

University of North Carolina - Departmental Grant

Keyword: Plastic Surgery

February, 2011
Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: Implications for glaucoma.

Comes N, Buie LK, Borras T

Genes Cells. 2011 Feb;16(2):243-59

University of North Carolina - Departmental Grant

Keyword: Glaucoma

January, 2010
Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma.

Spiga M, Borrás T

Invest Ophthalmol Vis Sci 2010;51(6):3029-3041

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Floppy eyelid syndrome as a subset of lax eyelid conditions: Relationships and clinical relevance (an ASOPRS thesis).

Fowler AM, Dutton JJ

Ophthal Plast Reconstr Surg 2010;26(3):195-204

University of North Carolina - Departmental Grant

Keyword: Plastic Surgery

Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys.

Buie LK, Rasmussen CA, Porterfield EC, Ramgolam VS, Choi VW, Markovic-Plese S, Samulski RJ, Kaufman PL, Borrás T

Invest Ophthalmol Vis Sci 2010;51(1):236-248

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Treatment of sheep steroid Induced ocular hypertension with a glucocorticoid-inducible MMP1 gene therapy virus.

Gerometta R, Spiga M, Borrás T, Candia OA

Invest Ophthalmol Vis Sci 2010;51(6):3042-3048

University of North Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Glaucoma

Uterine papillary serous carcinoma metastatic to the choroid.

Lawrence SD, Netland PA, Morris WR, Smiley L, Wilson MW

Retinal Cases & Brief Reports 2010;4(1):62-64

University of North Carolina - Departmental Grant

Keyword: Other: Uterine Papillary Serous Carcinoma

Visante™ OCT measurement of central corneal thickness following descemet’s stripping endothelial keratoplasty.

Lyles GW, Cohen KL

Ophthalmic Surg Lasers Imaging 2010;41:e1-e3

University of North Carolina - Departmental Grant

Keyword: Cornea

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