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Research to Prevent Blindness

Research Database

University of Michigan Research, funded by RPB in 2014 matching Departmental Grant

19 Citations, Sorted by Month and Year

October, 2014
Hypothesis-independent pathway analysis implicates GABA and Acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma.

Bailey JN, Yaspan BL, Pasquale LR, Hauser MA, Kang JH, Loomis SJ, Brilliant M, Budenz DL, Christen WG, Fingert J, Gaasterland D, Gaasterland T, Kraft P, Lee RK, Lichter PR, Liu Y, McCarty CA, Moroi SE, Richards JE, Realini T, Schuman JS, Scott WK, Singh K, Sit AJ, Vollrath D, Wollstein G, Zack DJ, Zhang K, Pericak-Vance MA, Allingham RR, Weinreb RN, Haines JL, Wiggs JL

Hum Genet. 2014 Oct;133(10):1319-30

University of Michigan - Departmental Grant

Keyword: Glaucoma

Risk factors associated with developing branch retinal vein occlusion among enrollees in a united states managed care plan.

Newman-Casey PA, Stem M, Talwar N, Musch DC, Besirli CG, Stein JD

Ophthalmology. 2014 Oct;121(10):1939-48

University of Michigan - Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Health Services Research

September, 2014
PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: Modulation by PTEN.

Li B, Smith TJ

J Clin Endocrinol Metab. 2014 Sep;99(9):3363-72

University of Michigan - Departmental Grant

Keyword: Thyroid Ophthalmology

Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes.

Chen H, Mester T, Raychaudhuri N, Kauh CY, Gupta S, Smith TJ, Douglas RS

J Clin Endocrinol Metab. 2014 Sep;99(9):1635-40

University of Michigan - Departmental Grant

Keyword: Thyroid Ophthalmology

July, 2014
Expression of thyrotropin receptor, thyroglobulin, sodium-iodide symporter, and thyroperoxidase by fibrocytes depends on AIRE.

Fernando R, Lu Y, Atkins SJ, Mester T, Branham K, Smith TJ

J Clin Endocrinol Metab. 2014 Jul;99(7):E1236-44

University of Michigan - Departmental Grant

Keyword: Thyroid Ophthalmology

Molecular Diagnostic Testing by eyeGENE(R).

Alapati AN, Goetz K, Suk J, Navani M, Al-Tarouti A, Jayasundera KT, Lee P, Tumminia SJ, Ayyagari R

Analysis of patients with hereditary retinal dystrophy phenotype involving central vision loss. Invest Ophthalmol Vis Sci. 2014 Jul;55(9):5510-21

University of Michigan - Departmental Grant

Keywords: Retina/Retinal Diseases, Gene Research/Therapy, AMD, Other: Genetics

Rituximab (Rituxan(R)) therapy for severe thyroid associated ophthalmopathy diminishes IGF-1R T cells.

McCoy AN, Kim DS, Gillespie E, Atkins S, Smith TJ, Douglas RS

J Clin Endocrinol Metab. 2014 Jul;99(7):E1294-9

University of Michigan - Departmental Grant

Keyword: Thyroid Ophthalmology

June, 2014
Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma.

Kang JH, Loomis SJ, Yaspan BL, Bailey JC, Weinreb RN, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Gaasterland D, Gaasterland T, Friedman DS, McCarty CA, Moroi SE, Olson L, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Brilliant M, Sit AJ, Christen WG, Fingert J, Forman JP, Buys ES, Kraft P, Zhang K, Allingham RR, Pericak-Vance MA, Richards JE, Hauser MA, Haines JL, Wiggs JL, Pasquale LR

Eye (Lond). 2014 Jun;28(6):662-71

University of Michigan - Departmental Grant

Keywords: Glaucoma, Gene Research/Therapy, Other: Genetics

May, 2014
Advances in understanding autoimmune pituitary disease: standardized methods for autoantibody detection.

Smith TJ

J Clin Endocrinol Metab. 2014 May;99(5):1589-92

University of Michigan - Departmental Grant

Keywords: Thyroid Ophthalmology, Other: Autoimmune

Human fibrocytes express multiple antigens associated with autoimmune endocrine diseases.

Fernando R, Vonberg A, Atkins SJ, Pietropaolo S, Pietropaolo M, Smith TJ

J Clin Endocrinol Metab. 2014 May;99(5):E796-803

University of Michigan - Departmental Grant

Keyword: Thyroid Ophthalmology

Thyrotropin receptor and CD40 mediate interleukin-8 expression in fibrocytes: implications for thyroid associated ophthalmopathy.

Douglas RS, Mester T, Ginter A, Kim D

Trans Am Ophthalmol Soc. 2014 May;112:26-37

University of Michigan - Lew R. Wasserman Merit Award - Douglas, Raymond S / MD, PhD Departmental Grant

Keyword: Thyroid Ophthalmology

April, 2014
Circadian and non-circadian modulation of autophagy in photoreceptors and retinal pigment epithelium.

Yao J, Jia L, Shelby SJ, Ganios AM, Feathers K, Thompson DA, Zacks DN

Invest Ophthalmol Vis Sci. 2014 Apr;55(5):3237-46

University of Michigan - Departmental Grant

Keywords: Retina/Retinal Diseases, AMD, Retinitis Pigmentosa

Cost-effectiveness of bevacizumab and ranibizumab for newly diagnosed neovascular macular degeneration.

Stein JD, Newman-Casey PA, Mrinalini T, Lee PP, Hutton DW

Ophthalmology. 2014 Apr;121(4):936-45

University of Michigan - Physician-Scientist Award - Stein, Joshua D / MD, MS Departmental Grant

Keywords: Retina/Retinal Diseases, AMD, Other: Health Services Research

Regulation of IL-1 receptor antagonist by TSH in fibrocytes and orbital fibroblasts.

Li B, Smith TJ

J Clin Endocrinol Metab. 2014 Apr;99(4):E625-33

University of Michigan - Departmental Grant

Keyword: Thyroid Ophthalmology

March, 2014
Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.

Wang Y, Smith TJ

Invest Ophthalmol Vis Sci. 2014 Mar;55(3):1735-48

University of Michigan - Departmental Grant

Keyword: Thyroid Ophthalmology

The potential association between postmenopausal hormone use and primary open-angle glaucoma.

Newman-Casey PA, Talwar N, Nan B, Musch DC, Pasquale LR, Stein JD

JAMA Ophthalmol. 2014 Mar;132(3):298-303

University of Michigan - Departmental Grant

Keyword: Glaucoma

February, 2014
Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss.

Loomis SJ, Kang JH, Weinreb RN, Yaspan BL, Cooke Bailey JN, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, McCarty CA, Moroi SE, Olson L, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Brilliant M, Sit AJ, Christen WG, Fingert J, Kraft P, Zhang K, Allingham RR, Pericak-Vance MA, Richards JE, Hauser MA, Haines JL, Pasquale LR, Wiggs JL

Ophthalmology. 2014 Feb;121(2):508-16

University of Michigan - Departmental Grant

Keywords: Glaucoma, Gene Research/Therapy, Imaging

January, 2014
Congenital cataracts: De novo gene conversion event in CRYBB2.

Garnai SJ, Huyghe JR, Reed DM, Scott KM, Liebmann JM, Boehnke M, Richards JE, Ritch R, Pawar H

Mol Vision. 2014 20:1579-93

University of Michigan - Departmental Grant

Keywords: Cataract, Gene Research/Therapy, Other: Genetics

Genome-wide association study and meta-analysis of intraocular pressure.

Ozel AB, Moroi SE, Reed DM, Nika M, Schmidt CM, Akbari S, Scott K, Rozsa F, Pawar H, Musch DC, Lichter PR, Gaasterland D, Branham K, Gilbert J, Garnai SJ, Chen W, Othman M, Heckenlively J, Swaroop A, Abecasis G, Friedman DS, Zack D, Ashley-Koch A, Ulmer M, Kang JH, Liu Y, Yaspan BL, Haines J, Allingham RR, Hauser MA, Pasquale L, Wiggs J, Richards JE, Li JZ

Hum Genet. 2014 Jan;133(1):41-57

University of Michigan - Departmental Grant

Keywords: Glaucoma, Gene Research/Therapy, Other: Genetics

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