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Research to Prevent Blindness

Research Database

University of California, San Diego Research, funded by RPB in 2014 matching Departmental Grant

34 Citations, Sorted by Month and Year

December, 2014
Relationship between ganglion cell layer thickness and estimated retinal ganglion cell counts in the glaucomatous macula.

Zhang C, Tatham AJ, Weinreb RN, Zangwill LM, Yang Z, Zhang JZ, Medeiros FA

Ophthalmology. 2014 Dec;121(12):2371-9

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Imaging

Retinal ganglion cell polarization using immobilized guidance cues on a tissue-engineered scaffold.

Kador KE, Alsehli HS, Zindell AN, Lau LW, Andreopoulos FM, Watson BD, Goldberg JL

Acta Biomater. 2014 Dec;10(12):4939-46

University of California, San Diego - Departmental Grant

Keyword: Glaucoma

The role of soluble adenylyl cyclase in neurite outgrowth.

Stiles TL, Kapiloff MS, Goldberg JL

Biochim Biophys Acta. 2014 Dec;1842(12 Pt B):2561-8

University of California, San Diego - Departmental Grant

Keywords: Cornea, Imaging

November, 2014
Glaucomatous retinal nerve fiber layer thickness loss is associated with slower reaction times under a divided attention task.

Tatham AJ, Boer ER, Rosen PN, Della Penna M, Meira-Freitas D, Weinreb RN, Zangwill LM, Medeiros FA

Am J Ophthalmol. 2014 Nov;158(5):1008-17

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Neuro-Ophthalmology

October, 2014
Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma.

Bailey JN, Yaspan BL, Pasquale LR, Hauser MA, Kang JH, Loomis SJ, Brilliant M, Budenz DL, Christen WG, Fingert J, Gaasterland D, Gaasterland T, Kraft P, Lee RK, Lichter PR, Liu Y, McCarty CA, Moroi SE, Richards JE, Realini T, Schuman JS, Scott WK, Singh K, Sit AJ, Vollrath D, Wollstein G, Zack DJ, Zhang K, Pericak-Vance MA, Allingham RR, Weinreb RN, Haines JL, Wiggs JL

Hum Genet. 2014 Oct;133(10):1319-30

University of California, San Diego - Departmental Grant

Keyword: Glaucoma

September, 2014
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.

Springelkamp H, Hohn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, Xu L, Mountain JE, Gharahkhani P, Lu Y, Amin N, Karssen LC, Sim KS, van Leeuwen EM, Iglesias AI, Verhoeven VJ, Hauser MA, Loon SC, Despriet DD, Nag A, Venturini C, Sanfilippo PG, Schillert A, Kang JH, Landers J, Jonasson F, Cree AJ, van Koolwijk LM, Rivadeneira F, Souzeau E, Jonsson V, Menon G, Blue Mountains Eye Study-GWAS group, Weinreb RN, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A, Ennis S, Thorsteinsdottir U, Burdon KP, NEIGHBORHOOD Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), Spector TD, Mirshahi A, Saw SM, Vingerling JR, Teo YY, Haines JL, Wolfs RC, Lemij HG, Tai ES, Jansonius NM, Jonas JB, Cheng CY, Aung T, Viswanathan AC, Klaver CC, Craig JE, Macgregor S, Mackey DA, Lotery AJ, Stefansson K, Bergen AA, Young TL, Wiggs JL, Pfeiffer N, Wong TY, Pasquale LR, Hewitt AW, van Duijn CM, Hammond CJ

Nat Commun. 2014 Sep 22;5:4883

University of California, San Diego - Departmental Grant

Keywords: Cornea, Glaucoma, Optic Neuropathy

Primary cilia signaling mediates intraocular pressure sensation.

Luo N, Conwell MD, Chen X, Kettenhofen CI, Westlake CJ, Cantor LB, Wells CD, Weinreb RN, Corson TW, Spandau DF, Joos KM, Iomini C, Obukhov AG, Sun Y

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12871-6

University of California, San Diego - Departmental Grant

Keywords: Cataract, Glaucoma, Retinitis Pigmentosa

August, 2014
Estimated rates of retinal ganglion cell loss in glaucomatous eyes with and without optic disc hemorrhages.

Gracitelli CP, Tatham AJ, Zangwill LM, Weinreb RN, Liu T, Medeiros FA

PLoS One. 2014 Aug 26;9(8):e105611

University of California, San Diego - Departmental Grant

Keywords: Cornea, Glaucoma, Optic Neuropathy

July, 2014
Isolation and characterization of mesenchymal progenitor cells from human orbital adipose tissue.

Chen SY, Mahabole M, Horesh E, Wester S, Goldberg JL, Tseng SC

Invest Ophthalmol Vis Sci. 2014 Jul 3;55(8):4842-52

University of California, San Diego - Departmental Grant

Keyword: Cornea

Learning from data: Recognizing glaucomatous defect patterns and detecting progression from visual field measurements.

Yousefi S, Goldbaum MH, Balasubramanian M, Medeiros FA, Zangwill LM, Liebmann JM, Girkin CA, Weinreb RN, Bowd C

IEEE Trans Biomed Eng. 2014 Jul;61(7):2112-24

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Optic Neuropathy

Rates of retinal nerve fiber layer thinning in glaucoma suspect eyes.

Miki A, Medeiros FA, Weinreb RN, Jain S, He F, Sharpsten L, Khachatryan N, Hammel N, Liebmann JM, Girkin CA, Sample PA, Zangwill LM

Ophthalmology. 2014 Jul;121(7):1350-8

University of California, San Diego - Departmental Grant

Keywords: Cornea, Glaucoma, Retina/Retinal Diseases

June, 2014
Assessment of optic nerve head drusen using enhanced depth imaging and swept source optical coherence tomography.

Silverman AL, Tatham AJ, Medeiros FA, Weinreb RN

J Neuroophthalmol. 2014 Jun;34(2):198-205

University of California, San Diego - Departmental Grant

Keywords: Imaging, Optic Neurology

Detecting glaucoma using automated pupillography.

Tatham AJ, Meira-Freitas D, Weinreb RN, Zangwill LM, Medeiros FA

Ophthalmology. 2014 Jun;121(6):1185-93

University of California, San Diego - Departmental Grant

Keyword: Glaucoma

Diagnostic ability of spectral-domain versus time-domain optical coherence tomography in preperimetric glaucoma.

Jeoung JW, Kim TW, Weinreb RN, Kim SH, Park KH, Kim DM

J Glaucoma. 2014 Jun-Jul;23(5):299-306

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Optic Neuropathy

Regulation of intrinsic axon growth ability at retinal ganglion cell growth cones.

Steketee MB, Oboudiyat C, Daneman R, Trakhtenberg E, Lamoureux P, Weinstein JE, Heidemann S, Barres BA, Goldberg JL

Invest Ophthalmol Vis Sci. 2014 Jun 6;55(7):4369-77

University of California, San Diego - Departmental Grant

Keyword: Imaging

Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma.

Kang JH, Loomis SJ, Yaspan BL, Bailey JC, Weinreb RN, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Gaasterland D, Gaasterland T, Friedman DS, McCarty CA, Moroi SE, Olson L, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Brilliant M, Sit AJ, Christen WG, Fingert J, Forman JP, Buys ES, Kraft P, Zhang K, Allingham RR, Pericak-Vance MA, Richards JE, Hauser MA, Haines JL, Wiggs JL, Pasquale LR

Eye (Lond). 2014 Jun;28(6):662-71

University of California, San Diego - Departmental Grant

Keywords: Cornea, Glaucoma

May, 2014
Evaluation of retinal and choroidal thickness by swept-source optical coherence tomography: Repeatability and assessment of artifacts.

Mansouri K, Medeiros FA, Tatham AJ, Marchase N, Weinreb RN

Am J Ophthalmol. 2014 May;157(5):1022-32

University of California, San Diego - Departmental Grant

Keywords: Diabetic Retinopathy, Glaucoma, Imaging

Regulating set-beta's subcellular localization toggles its function between inhibiting and promoting axon growth and regeneration.

Trakhtenberg EF, Wang Y, Morkin MI, Fernandez SG, Mlacker GM, Shechter JM, Liu X, Patel KH, Lapins A, Yang S, Dombrowski SM, Goldberg JL

J Neurosci. 2014 May 21;34(21):7361-74

University of California, San Diego - Departmental Grant

Keyword: Neuro-Ophthalmology

The pathophysiology and treatment of glaucoma: A review.

Weinreb RN, Aung T, Medeiros FA

JAMA. 2014 May 14;311(18):1901-11

University of California, San Diego - Departmental Grant

Keywords: Cataract, Dry Eye, Glaucoma, Optic Neuropathy

April, 2014
Acute retinal pigment epithelium detachments after photocoagulation.

Moysidis SN, Vajzovic L, Gregori G, Goldberg JL

Retina. 2014 Apr;34(4):749-60

University of California, San Diego - Departmental Grant

Keyword: Retinitis Pigmentosa

Coenzyme Q10 ameliorates oxidative stress and prevents mitochondrial alteration in ischemic retinal injury.

Lee D, Kim KY, Shim MS, Kim SY, Ellisman MH, Weinreb RN, Ju WK

Apoptosis. 2014 Apr;19(4):603-14

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Imaging

Glaucoma progression detection using structural retinal nerve fiber layer measurements and functional visual field points.

Yousefi S, Goldbaum MH, Balasubramanian M, Jung TP, Weinreb RN, Medeiros FA, Zangwill LM, Liebmann JM, Girkin CA, Bowd C

IEEE Trans Biomed Eng. 2014 Apr;61(4):1143-54

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Imaging, Optic Neuropathy

Retinal repair with induced pluripotent stem cells.

Al-Shamekh S, Goldberg JL

Transl Res. 2014 Apr;163(4):377-86

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Retinitis Pigmentosa

March, 2014
Detecting glaucoma progression from localized rates of retinal changes in parametric and nonparametric statistical framework with type I error control.

Balasubramanian M, Arias-Castro E, Medeiros FA, Kriegman DJ, Bowd C, Weinreb RN, Holst M, Sample PA, Zangwill LM

Invest Ophthalmol Vis Sci. 2014 Mar 19;55(3):1684-95

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Imaging

Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury.

Kim SY, Shim MS, Kim KY, Weinreb RN, Wheeler LA, Ju WK

Cell Death Dis. 2014 Mar 6;5:e1105

University of California, San Diego - Departmental Grant

Keyword: Glaucoma

February, 2014
Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss.

Loomis SJ, Kang JH, Weinreb RN, Yaspan BL, Cooke Bailey JN, Gaasterland D, Gaasterland T, Lee RK, Lichter PR, Budenz DL, Liu Y, Realini T, Friedman DS, McCarty CA, Moroi SE, Olson L, Schuman JS, Singh K, Vollrath D, Wollstein G, Zack DJ, Brilliant M, Sit AJ, Christen WG, Fingert J, Kraft P, Zhang K, Allingham RR, Pericak-Vance MA, Richards JE, Hauser MA, Haines JL, Pasquale LR, Wiggs JL

Ophthalmology. 2014 Feb;121(2):508-16

University of California, San Diego - Departmental Grant

Keyword: Glaucoma

Coenzyme Q10 inhibits glutamate excitotoxicity and oxidative stress-mediated mitochondrial alteration in a mouse model of glaucoma.

Lee D, Shim MS, Kim KY, Noh YH, Kim H, Kim SY, Weinreb RN, Ju WK

Invest Ophthalmol Vis Sci. 2014 Feb 18;55(2):993-1005

University of California, San Diego - Departmental Grant

Keyword: Glaucoma

Outflow tract ablation using a conditionally cytotoxic feline immunodeficiency viral vector.

Zhang Z, Dhaliwal AS, Tseng H, Kim JD, Schuman JS, Weinreb RN, Loewen NA

Invest Ophthalmol Vis Sci. 2014 Feb 18;55(2):935-40

University of California, San Diego - Departmental Grant

Keywords: Cornea, Glaucoma, Imaging

Predicting progression of glaucoma from rates of frequency doubling technology perimetry change.

Meira-Freitas D, Tatham AJ, Lisboa R, Kuang TM, Zangwill LM, Weinreb RN, Girkin CA, Liebmann JM, Medeiros FA

Ophthalmology. 2014 Feb;121(2):498-507

University of California, San Diego - Departmental Grant

Keywords: Cornea, Glaucoma

January, 2014
Defects of the lamina cribrosa in eyes with localized retinal nerve fiber layer loss.

Tatham AJ, Miki A, Weinreb RN, Zangwill LM, Medeiros FA

Ophthalmology. 2014 Jan;121(1):110-8

University of California, San Diego - Departmental Grant

Keywords: Cornea, Glaucoma, Imaging

Evaluation of progressive neuroretinal rim loss as a surrogate end point for development of visual field loss in glaucoma.

Medeiros FA, Lisboa R, Zangwill LM, Liebmann JM, Girkin CA, Bowd C, Weinreb RN

Ophthalmology. 2014 Jan;121(1):100-9

University of California, San Diego - Departmental Grant

Keywords: Cornea, Glaucoma, Imaging

Glaucomatous patterns in frequency doubling technology (FDT) perimetry data identified by unsupervised machine learning classifiers.

Bowd C, Weinreb RN, Balasubramanian M, Lee I, Jang G, Yousefi S, Zangwill LM, Medeiros FA, Girkin CA, Liebmann JM, Goldbaum MH

PLoS One. 2014 Jan 30;9(1):e85941

University of California, San Diego - Departmental Grant

Keywords: Glaucoma, Imaging, Optic Neuropathy

Solutions in pediatric cataracts.

Robbins SL, Breidenstein B, Granet DB

Curr Opin Ophthalmol. 2014 Jan;25(1):12-8

University of California, San Diego - Departmental Grant

Keywords: Cataract, Cornea, Glaucoma, Pediatric, Retinal Detachment

Survival and integration of developing and progenitor-derived retinal ganglion cells following transplantation.

Hertz J, Qu B, Hu Y, Patel RD, Valenzuela DA, Goldberg JL

Cell Transplant. 2014;23(7):855-72

University of California, San Diego - Departmental Grant

Keyword: Cornea

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