Involvement of YAP, TAZ and HSP90 in contact guidance and intercellular junction formation in corneal epithelial cells.

Raghunathan VK, Dreier B, Morgan JT, Tuyen BC, Rose BW, Reilly CM, Russell P, Murphy CJ

PLoS One. 2014 Oct 7;9(10):e109811

University of California, Davis - Departmental Grant

Keyword: Cornea

The formation of cortical actin arrays in human trabecular meshwork cells in response to cytoskeletal disruption.

Murphy KC, Morgan JT, Wood JA, Sadeli A, Murphy CJ, Russell P

Exp Cell Res. 2014 Oct 15;328(1):164-71

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Automated AFM force curve analysis for determining elastic modulus of biomaterials and biological samples.

Chang YR, Raghunathan VK, Garland SP, Morgan JT, Russell P, Murphy CJ

J Mech Behav Biomed Mater. 2014 Sep;37:209-18

University of California, Davis - Departmental Grant

Keyword: Nanotechnology/Drug Delivery

Rapid light-induced activation of retinal microglia in mice lacking arrestin-1.

Levine ES, Zam A, Zhang P, Pechko A, Wang X, FitzGerald P, Pugh EN,Jr, Zawadzki RJ, Burns ME

Vision Res. 2014 Sep;102:71-9

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

The dose-dependent macular thickness changes assessed by fd-oct in patients with retinitis pigmentosa treated with ciliary neurotrophic factor.

Pilli S, Zawadzki RJ, Telander DG

Retina. 2014 Jul;34(7):1384-90

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Balanced cortical microcircuitry for spatial working memory based on corrective feedback control.

Lim S, Goldman MS

J Neurosci. 2014 May 14;34(20):6790-806

University of California, Davis - Departmental Grant

Keyword: Neuro-Ophthalmology

Improving visual outcomes by preserving outer retina morphology in eyes with resolved pseudophakic cystoid macular edema.

Hunter AA, Modjtahedi SP, Long K, Zawadzki R, Chin EK, Caspar JJ, Morse LS, Telander DG

J Cataract Refract Surg. 2014 Apr;40(4):626-31

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

A cell culture substrate with biologically relevant size-scale topography and compliance of the basement membrane.

Garland SP, McKee CT, Chang YR, Raghunathan VK, Russell P, Murphy CJ

Langmuir. 2014 Mar 4;30(8):2101-8

University of California, Davis - Departmental Grant

Keyword: Cornea

Human trabecular meshwork cells exhibit several characteristics of, but are distinct from, adipose-derived mesenchymal stem cells.

Morgan JT, Wood JA, Walker NJ, Raghunathan VK, Borjesson DL, Murphy CJ, Russell P

J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):254-66

University of California, Davis - Departmental Grant

Nonmydriatic fundus photography for teleophthalmology diabetic retinopathy screening in rural and urban clinics.

Chin EK, Ventura BV, See KY, Seibles J, Park SS

Telemed J E Health. 2014 Feb;20(2):102-8

University of California, Davis - Departmental Grant

Keyword: Diabetic Retinopathy

Phase-variance optical coherence tomography: A technique for noninvasive angiography.

Schwartz DM, Fingler J, Kim DY, Zawadzki RJ, Morse LS, Park SS, Fraser SE, Werner JS

Ophthalmology. 2014 Jan;121(1):180-7

University of California, Davis - Departmental Grant

Keyword: AMD

Robust and artifact-free mounting of tissue samples for atomic force microscopy.

Morgan JT, Raghunathan VK, Thomasy SM, Murphy CJ, Russell P

BioTechniques. 2014 Jan;56(1):40-2

University of California, Davis - Departmental Grant

Keyword: Cornea

Wavefront sensorless adaptive optics optical coherence tomography for in vivo retinal imaging in mice.

Jian Y, Xu J, Gradowski MA, Bonora S, Zawadzki RJ, Sarunic MV

Biomed Opt Express. 2014 Jan 21;5(2):547-59

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Safety and immunomodulatory effects of allogeneic canine adipose-derived mesenchymal stromal cells transplanted into the region of the lacrimal gland, the gland of the third eyelid and the knee joint.

Park SA, Reilly CM, Wood JA, Chung DJ, Carrade DD, Deremer SL, Seraphin RL, Clark KC, Zwingenberger AL, Borjesson DL, Hayashi K, Russell P, Murphy CJ

Cytotherapy. 2013 Dec;15(12):1498-510

University of California, Davis - Departmental Grant

Keyword: Stem Cell Research/Therapy

Five-year follow-up of macular morphologic changes after rhegmatogenous retinal detachment repair: Fourier domain OCT findings.

Rashid S, Pilli S, Chin EK, Zawadzki RJ, Werner JS, Park SS

Retina. 2013 Nov-Dec;33(10):2049-58

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Improved visualization of outer retinal morphology with aberration cancelling reflective optical design for adaptive optics - optical coherence tomography.

Lee SH, Werner JS, Zawadzki RJ

Biomed Opt Express. 2013 Oct 17;4(11):2508-17

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Paraneoplastic optic neuropathy and retinopathy associated with colon adenocarcinoma.

Chao D, Chen WC, Thirkill CE, Lee AG

Can J Ophthalmol. 2013 Oct;48(5):e116-20

University of California, Davis - Departmental Grant

Keyword: Epidemiology

Vitreous and aqueous penetration of orally administered trimethoprim-sulfamethoxazole combination in humans.

Feiz V, Nijm L, Glickman RD, Morse LS, Telander DG, Park SS, Polage CR, Christiansen SM, Moshirfar M

Cornea. 2013 Oct;32(10):1315-20

University of California, Davis - Departmental Grant

Keyword: Nanotechnology/Drug Delivery

What do mechanotransduction, hippo, wnt, and TGFbeta have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease.

Morgan JT, Murphy CJ, Russell P

Exp Eye Res. 2013 Oct;115:1-12

University of California, Davis - Departmental Grant

Keyword: Other: Biophysical Cueing

A modeling framework for deriving the structural and functional architecture of a short-term memory microcircuit.

Fisher D, Olasagasti I, Tank DW, Aksay ER, Goldman MS

Neuron. 2013 Sep 4;79(5):987-1000

University of California, Davis - Departmental Grant

Keyword: Other: Oculomotor Memory Circuit

Balanced cortical microcircuitry for maintaining information in working memory.

Lim S, Goldman MS

Nat Neurosci. 2013 Sep;16(9):1306-14

University of California, Davis - Departmental Grant

Keyword: Other: Oculomotor Memory Circuit

Adherence to glaucoma medication: The effect of interventions and association with personality type.

Lim MC, Watnik MR, Imson KR, Porter SM, Granier AM

J Glaucoma. 2013 Aug;22(6):439-46

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Influence of extracellular matrix proteins and substratum topography on corneal epithelial cell alignment and migration.

Raghunathan V, McKee C, Cheung W, Naik R, Nealey PF, Russell P, Murphy CJ

Tissue Eng Part A. 2013 Aug;19(15-16):1713-22

University of California, Davis - Departmental Grant

Keyword: Cornea

Optical imaging of the chorioretinal vasculature in the living human eye.

Kim DY, Fingler J, Zawadzki RJ, Park SS, Morse LS, Schwartz DM, Fraser SE, Werner JS

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14354-9

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Persistent biases in subjective image focus following cataract surgery.

Parkosadze K, Kalmakhelidze T, Tolmacheva M, Chichua G, Kezeli A, Webster MA, Werner JS

Vision Res. 2013 Aug 30;89:10-7

University of California, Davis - Departmental Grant

Keyword: Cataract

Substratum compliance modulates corneal fibroblast to myofibroblast transformation.

Dreier B, Thomasy SM, Mendonsa R, Raghunathan VK, Russell P, Murphy CJ

Invest Ophthalmol Vis Sci. 2013 Aug 28;54(8):5901-7

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Substratum stiffness and latrunculin B modulate the gene expression of the mechanotransducers YAP and TAZ in human trabecular meshwork cells.

Thomasy SM, Morgan JT, Wood JA, Murphy CJ, Russell P

Exp Eye Res. 2013 Aug;113:66-73

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Three-dimensional anterior segment imaging in patients with type 1 boston keratoprosthesis with switchable full depth range swept source optical coherence tomography.

Poddar R, Cortes DE, Werner JS, Mannis MJ, Zawadzki RJ

J Biomed Opt. 2013 Aug;18(8):86002

University of California, Davis - Departmental Grant

Keyword: Cornea

High-resolution spectral domain anterior segment optical coherence tomography in type 1 boston keratoprosthesis.

Shapiro BL, Cortes DE, Chin EK, Li JY, Werner JS, Redenbo E, Mannis MJ

Cornea. 2013 Jul;32(7):951-5

University of California, Davis - Departmental Grant

Keyword: Cornea

Staging of macular telangiectasia: Power-doppler optical coherence tomography and macular pigment optical density.

Chin EK, Kim DY, Hunter AA,3rd, Pilli S, Wilson M, Zawadzki RJ, Werner JS, Park SS

Invest Ophthalmol Vis Sci. 2013 Jul 2;54(7):4459-70

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Anterior segment OCT and confocal microscopy findings in atypical corneal intraepithelial neoplasia.

Chin EK, Cortes DE, Lam A, Mannis MJ

Cornea. 2013 Jun;32(6):875-9

University of California, Davis - Departmental Grant

Keyword: Cornea

Multimodal assessment of microscopic morphology and retinal function in patients with geographic atrophy.

Panorgias A, Zawadzki RJ, Capps AG, Hunter AA, Morse LS, Werner JS

Invest Ophthalmol Vis Sci. 2013 Jun 26;54(6):4372-84

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Pediatric internuclear ophthalmoplegia.

Rizzo JL, Lloyd M, O'Hara MA

J Neuroophthalmol. 2013 Jun;33(2):134-6

University of California, Davis - Departmental Grant

Keyword: Pediatric

Survey of patients with age-related macular degeneration: Knowledge and adherence to recommendations.

Shah SU, Pilli S, Telander DG, Morse LS, Park SS

Can J Ophthalmol. 2013 Jun;48(3):204-9

University of California, Davis - Departmental Grant

Keyword: AMD

The rate of structural change: The confocal scanning laser ophthalmoscopy ancillary study to the ocular hypertension treatment study.

Zangwill LM, Jain S, Dirkes K, He F, Medeiros FA, Trick GL, Brandt JD, Cioffi GA, Coleman AL, Liebmann JM, Piltz-Seymour JR, Gordon MO, Kass MA, Weinreb RN, Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study

Am J Ophthalmol. 2013 Jun;155(6):971-82

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Adaptive optics optical coherence tomography for in vivo mouse retinal imaging.

Jian Y, Zawadzki RJ, Sarunic MV

J Biomed Opt. 2013 May;18(5):56007

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Pediatric penetrating keratoplasty.

O'Hara MA, Mannis MJ

Int Ophthalmol Clin. 2013 Spring;53(2):59-70

University of California, Davis - Departmental Grant

Keyword: Cornea

Pancreatic neuroendocrine paraneoplastic optic neuropathy: Confirmation with antibody to optic nerve and hepatic metastasis.

Slamovits TL, Posner JB, Reidy DL, Thirkill CE, Keltner JL

J Neuroophthalmol. 2013 Mar;33(1):21-5

University of California, Davis - Departmental Grant

Keyword: Optic Neuropathy

The comparative histologic effects of subthreshold 532- and 810-nm diode micropulse laser on the retina.

Yu AK, Merrill KD, Truong SN, Forward KM, Morse LS, Telander DG

Invest Ophthalmol Vis Sci. 2013 Mar 1;54(3):2216-24

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

NMDA and GABAB (KIR) conductances: The "perfect couple" for bistability.

Sanders H, Berends M, Major G, Goldman MS, Lisman JE

J Neurosci. 2013 Jan 9;33(2):424-9

University of California, Davis - Departmental Grant

Keyword: Other: Neuronal Firing

Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ.

Raghunathan VK, Morgan JT, Dreier B, Reilly CM, Thomasy SM, Wood JA, Ly I, Tuyen BC, Hughbanks M, Murphy CJ, Russell P

Invest Ophthalmol Vis Sci. 2013 Jan 14;54(1):378-86

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Compliance profile of the human cornea as measured by atomic force microscopy.

Last JA, Thomasy SM, Croasdale CR, Russell P, Murphy CJ

Micron. 2012 Dec;43(12):1293-8

University of California, Davis - Departmental Grant

Keyword: Cornea

Dopamine and full-field illumination activate D1 and D2-D5-type receptors in adult rat retinal ganglion cells.

Ogata G, Stradleigh TW, Partida GJ, Ishida AT

J Comp Neurol. 2012 Dec 1;520(17):4032-49

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

The modulation of canine mesenchymal stem cells by nano-topographic cues.

Wood JA, Ly I, Borjesson DL, Nealey PF, Russell P, Murphy CJ

Exp Cell Res. 2012 Nov 15;318(19):2438-45

University of California, Davis - Departmental Grant

Keyword: Stem Cell Research/Therapy

Outcomes of fornix-based versus limbus-based conjunctival incisions for glaucoma drainage device implant.

Suhr AW, Lim MC, Brandt JD, Izquierdo JC, Willits N

J Glaucoma. 2012 Oct-Nov;21(8):523-9

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Eyelash alopecia areata: Case series and literature review.

Modjtahedi BS, Kishan AU, Schwab IR, Jackson WB, Maibach HI

Can J Ophthalmol. 2012 Aug;47(4):333-8

University of California, Davis - Departmental Grant

Keywords: Epidemiology, Other: Alopecia Areata

Glycomic analysis of tear and saliva in ocular rosacea patients: The search for a biomarker.

Vieira AC, An HJ, Ozcan S, Kim JH, Lebrilla CB, Mannis MJ

Ocul Surf. 2012 Jul;10(3):184-92

University of California, Davis - Departmental Grant

Keyword: Cornea

Practice patterns and opinions in the management of recurrent or chronic herpes zoster ophthalmicus.

Sy A, McLeod SD, Cohen EJ, Margolis TP, Mannis MJ, Lietman TM, Acharya NR

Cornea. 2012 Jul;31(7):786-90

University of California, Davis - Departmental Grant

Keyword: Cornea

Periocular and intra-articular injection of canine adipose-derived mesenchymal stem cells: An in vivo imaging and migration study.

Wood JA, Chung DJ, Park SA, Zwingenberger AL, Reilly CM, Ly I, Walker NJ, Vernau W, Hayashi K, Wisner ER, Cannon MS, Kass PH, Cherry SR, Borjesson DL, Russell P, Murphy CJ

J Ocul Pharmacol Ther. 2012 Jun;28(3):307-17

University of California, Davis - Departmental Grant

Keyword: Stem Cell Research/Therapy

New directions in ophthalmic optical coherence tomography.

Wojtkowski M, Kaluzny B, Zawadzki RJ

Optom Vis Sci. 2012 May;89(5):524-42

University of California, Davis - Departmental Grant

Keyword: Imaging

Postoperative complications in the tube versus trabeculectomy (TVT) study during five years of follow-up.

Gedde SJ, Herndon LW, Brandt JD, Budenz DL, Feuer WJ, Schiffman JC, Tube Versus Trabeculectomy Study Group

Am J Ophthalmol. 2012 May;153(5):804,814.e1

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Unusual paraneoplastic cause of vision loss: Combined paraneoplastic cone dystrophy and optic neuropathy.

Finger ML, Thirkill CE, Borruat FX

Arch Ophthalmol. 2012 May 1;130(5):660-2

University of California, Davis - Departmental Grant

Keyword: Optic Neuropathy

Altered stability of mRNAs associated with glaucoma progression in human trabecular meshwork cells following oxidative stress.

Mochizuki H, Murphy CJ, Brandt JD, Kiuchi Y, Russell P

Invest Ophthalmol Vis Sci. 2012 Apr 2;53(4):1734-41

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Effect of optical defocus on performance of dogs involved in field trial competition.

Ofri R, Hollingsworth SR, Groth A, Motta MJ, Doval JH, Kass PH, Murphy CJ

Am J Vet Res. 2012 Apr;73(4):546-50

University of California, Davis - Departmental Grant

Keyword: Myopia/Presbyopia

Outer retinal structure in patients with acute zonal occult outer retinopathy.

Mkrtchyan M, Lujan BJ, Merino D, Thirkill CE, Roorda A, Duncan JL

Am J Ophthalmol. 2012 Apr;153(4):757,68, 768.e1

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Adjusting intraocular pressure for central corneal thickness does not improve prediction models for primary open-angle glaucoma.

Brandt JD, Gordon MO, Gao F, Beiser JA, Miller JP, Kass MA, Ocular Hypertension Treatment Study Group

Ophthalmology. 2012 Mar;119(3):437-42

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Reproducibility of macular thickness measurement among five OCT instruments: Effects of image resolution, image registration, and eye tracking.

Chin EK, Sedeek RW, Li Y, Beckett L, Redenbo E, Chandra K, Park SS

Ophthalmic Surg Lasers Imaging. 2012 Mar-Apr;43(2):97-108

University of California, Davis - Departmental Grant

Keyword: Imaging

The influence of a biologically relevant substratum topography on human aortic and umbilical vein endothelial cells.

McKee CT, Wood JA, Ly I, Russell P, Murphy CJ

Biophys J. 2012 Mar 7;102(5):1224-33

University of California, Davis - Departmental Grant

Keyword: Other: Bioengineered Surfaces

Thy1 associates with the cation channel subunit HCN4 in adult rat retina.

Partida GJ, Stradleigh TW, Ogata G, Godzdanker I, Ishida AT

Invest Ophthalmol Vis Sci. 2012 Mar 26;53(3):1696-703

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34+ cells in NOD-SCID mice with acute ischemia-reperfusion injury.

Park SS, Caballero S, Bauer G, Shibata B, Roth A, Fitzgerald PG, Forward KI, Zhou P, McGee J, Telander DG, Grant MB, Nolta JA

Invest Ophthalmol Vis Sci. 2012 Feb 23;53(2):986-94

University of California, Davis - Departmental Grant

Keyword: Stem Cell Research/Therapy

New developments in eye models with retina tissue phantoms for ophthalmic optical coherence tomography.

Rowe TS, Zawadzki RJ

Proc SPIE. 2012 Feb 1;8229:822913-

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Noise tolerance of attractor and feedforward memory models.

Lim S, Goldman MS

Neural Comput. 2012 Feb;24(2):332-90

University of California, Davis - Departmental Grant

Keywords: Epidemiology, Other: Neural Activity

Substratum stiffness and latrunculin B regulate matrix gene and protein expression in human trabecular meshwork cells.

Thomasy SM, Wood JA, Kass PH, Murphy CJ, Russell P

Invest Ophthalmol Vis Sci. 2012 Feb 23;53(2):952-8

University of California, Davis - Departmental Grant

Keyword: Glaucoma

Substratum topography modulates corneal fibroblast to myofibroblast transformation.

Myrna KE, Mendonsa R, Russell P, Pot SA, Liliensiek SJ, Jester JV, Nealey PF, Brown D, Murphy CJ

Invest Ophthalmol Vis Sci. 2012 Feb 21;53(2):811-6

University of California, Davis - Departmental Grant

Keyword: Cornea

Visualization of human retinal capillary networks: A comparison of intensity, speckle-variance and phase-variance optical coherence tomography.

Kim DY, Fingler J, Werner JS, Schwartz DM, Fraser SE, Zawadzki RJ

Proc SPIE. 2012 Feb 9;8213:821307-

University of California, Davis - Departmental Grant

Keyword: Retinal Vein and Artery Occlusion

FUnctional and anatomic consequences of subretinal dosing in the cynomolgus macaque.

Nork M, Murphy C, Kim C, VerHoeve J, Rasmussen C, Miller P, Wabers H, Neider M, Dubielzig R, McCulloh R, Christian B

Archives of Ophthalmology. 2012 January 1;130(1):65-75

University of California, Davis - Departmental Grant

Keyword: Retina/Retinal Diseases

Modulation of osteogenic differentiation in hMSCs cells by submicron topographically-patterned ridges and grooves.

Watari S, Hayashi K, Wood JA, Russell P, Nealey PF, Murphy CJ, Genetos DC

Biomaterials. 2012 Jan;33(1):128-36

University of California, Davis - Departmental Grant

Keyword: Stem Cell Research/Therapy

Noninvasive imaging of the foveal avascular zone with high-speed, phase-variance optical coherence tomography.

Kim DY, Fingler J, Zawadzki RJ, Park SS, Morse LS, Schwartz DM, Fraser SE, Werner JS

Invest Ophthalmol Vis Sci. 2012 Jan 5;53(1):85-92

University of California, Davis - Departmental Grant

Keyword: Retinal Vein and Artery Occlusion

Rapidly progressive homonymous hemianopia in the heidenhain variant of creutzfeldt-jakob disease.

Chin EK, Hershewe G, Keltner JL

Neuro-Ophthalmology. 2012 04/01; 2012/12;36(2):54-8

University of California, Davis - Departmental Grant

Keyword: Neuro-Ophthalmology