Recent RPB Research & Archives

Welcome to the RPB Research Archive.  Each year, more than 800 scientific studies are published citing RPB grant support, so you should be aware that your search request may produce extensive results, requiring you to scroll through them until you locate a result of specific relevance.  You can click on any of the article titles produced by your search to find an abstract providing an overview of the research.

Search instructions
To search the entire RPB Research Archive for scientific papers on a specific topic, by a specific author, or for bibliographies by eye disease, enter keywords in the box and click Search. 

To browse bibliographies by year, click on the links below and use the search capacity within each downloaded document (Word or PDF) to find specific terms.

59 citations match:

Recent Research

Activated CD11b+ CD15+ Granulocytes Increase in the Blood of Patients with Uveal Melanoma

Kyle C. McKenna, Kelly M. Beatty, Richard A. Bilonick, Lynn Schoenfield, Kira L. Lathrop, and Arun D. Singh
Invest. Ophthalmol. Vis. Sci. 2009 50: 4295-4303

Attenuation of Iodine 125 Radiation With Vitreous Substitutes in the Treatment of Uveal Melanoma

Scott C. N. Oliver; Min Y. Leu; John J. DeMarco; Philip E. Chow; Steve P. Lee; Tara A. McCannel
Arch Ophthalmol, Jul 2010; 128: 888 - 893.

Bevacizumab Suppression of Establishment of Micrometastases in Experimental Ocular Melanoma

Hua Yang, Martine J. Jager, and Hans E. Grossniklaus
Invest. Ophthalmol. Vis. Sci. 2010 51: 2835-2842.

Choroidal Melanoma Occurring in a Nonhuman Primate

Daniel M. Albert; Richard R. Dubielzig; Yong Li; Ton Lin; Aneesh Neekhra; Werhner Orilla; Meg Ramos; M. Shahriar Salamat; James A. Burke
Arch Ophthalmol, Aug 2009; 127: 1080 - 1082.

Constitutive Overexpression of Pigment Epithelium–Derived Factor Inhibition of Ocular Melanoma Growth and Metastasis

Hua Yang and Hans E. Grossniklaus
Invest. Ophthalmol. Vis. Sci. 2010 51: 28-34.

Effectiveness of Treatments for Metastatic Uveal Melanoma , 17 April 2009

James J. Augsburger, Zélia M. Corrêa, Adeel H. Shaikh
American Journal of Ophthalmology
July 2009 (Vol. 148, Issue 1, Pages 119-127)

Inhibition of Chemokine Receptor Expression on Uveal Melanomas by CXCR4 siRNA and Its Effect on Uveal Melanoma Liver Metastases

Haochuan Li, Wanhua Yang, Peter W. Chen, Hassan Alizadeh, and Jerry Y. Niederkorn
Invest. Ophthalmol. Vis. Sci. 2009 50: 5522-5528.

Molecular Prognostic Testing and Individualized Patient Care in Uveal Melanoma , 05 October 2009

J. William Harbour
American Journal of Ophthalmology
December 2009 (Vol. 148, Issue 6, Pages 823-829.e1)

Natural History of Radiation Papillopathy after Proton Beam Irradiation of Parapapillary Melanoma Corrected Proof, 05 April 2010

Ivana K. Kim, Anne Marie Lane, Kathleen M. Egan, John Munzenrider, Evangelos S. Gragoudas
Ophthalmology
DOI: 10.1016/j.ophtha.2009.12.015

Survival in Patients With Presymptomatic Diagnosis of Metastatic Uveal Melanoma

Ivana K. Kim; Anne Marie Lane; Evangelos S. Gragoudas
Arch Ophthalmol, Jul 2010; 128: 871 - 875.

 

2009 Research Archive

Activated CD11b+ CD15+ granulocytes increase in the blood of patients with uveal melanoma

McKenna KC, Beatty KM, Bilonick RA, Schoenfield L, Lathrop KL, Singh AD
Invest Ophthalmol Vis Sci 2009;50:4295-4303 (Univ. of Pittsburgh Medical School - Unres. Grant) Keyword(s): Melanoma

Blood vessel maturation in human uveal melanoma: spatial distribution of neovessels and mature vasculature

Piña Y, Cebulla CM, Murray TG, Alegret A, Dubovy SR, Boutrid H, Feuer W, Mutapcic L, Jockovich ME
Ophthalmic Res 2009;41(3):160-169 (Univ. of Miami, FL - Unres. Grant) Keyword(s): Retina/Retinal Diseases

Choroidal melanoma occurring in a nonhuman primate: Report of a case

Albert DM, Dubielzig RR, Li Y, Lin T, Neekhra A, Orilla W, Ramos M, Salamat MS, Burke JA
Arch Ophthalmol 2009;127(8):1080-1082 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Uveal Melanoma

Effectiveness of treatments for metastatic uveal melanoma

Augsburger JJ, Corrêa ZM, Shaikh AH
Am J Ophthalmol 2009;148(1):119-27 (Univ. of Cincinnati College of Medicine – Unres. Grant) Keyword(s): Ocular Oncology

Immune escape mechanisms of intraocular tumors

Niederkorn JY
Prog in Retinal and Eye Res 2009;28:329-347 (Univ. of Texas, Southwestern at Dallas – Unres. Grant) Keyword(s): Uveal Melanoma, Tumor

Inadvertent evisceration of eyes containing uveal melanoma

Eagle Jr RC, Grossniklaus HE, Syed N, Hogan RN, Lloyd 3rd WC, Folberg R
Arch Ophthalmol 2009;127:141-5 (Univ. of Iowa - Unres. Grant) Keyword(s): Ocular Neoplasms

Inadvertent evisceration of eyes containing uveal melanoma

Eagle RC, Grossniklaus HE, Nasreen S, Hogan RN, Lloyd WC, Folberg R
Arch Ophthalmol 2009;127(2):141-145 (Emory Univ. Eye Center - Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Melanoma, Ocular Pathology

Inhibition of chemokine receptor expression on uveal melanomas by CXCR4 siRNA and its effect on uveal melanoma liver metastases

Li H, Yang W, Chen PW, Alizadeh H, Niederkorn JY
Invest Ophthalmol Vis Sci. 2009;50(12):5522–5528 (Univ. of Texas, Southwestern at Dallas – Unres. Grant) Keyword(s): Tumor Immunology, Uveal Melanoma

Ocular complications following I-125 brachytherapy for choroidal melanoma

Wen JC, Oliver SC, McCannel TA
Eye 2009;23(6):1254-68 (Univ. of California, Los Angeles – Unres. Grant) Keyword(s): Choroidal Melanoma, Brachytherapy

Update on posterior unveal melanoma: treatment of the eye and emerging strategies in the prognosis and treatment of metastatic disease

Shildkrot Y, Wilson MW
Curr Opin Ophthalmol 2009;20:504-510 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): Neuro-Ophthalmology, Retina/Retinal Disease

 

2008 Research Archive

A metastasis modifier locus on human chromosome 8p in uveal melanoma identified by integrative genomic analysis

Onken MD, Worley LA, Harbour JW
Clin Cancer Res 2008;14:3737-3745 (Washington Univ. – Unres. Grant) Keyword(s): Uveal Melanoma

Assessment of central vision and macular structure in patients undergoing iodine-125 brachytherapy for ciliochoroidal melanoma

Oliver SC, Young TA, Kobe LH, Leu MY, Lee SP, Chun MW, Straatsma BR
Am J Clin Oncol 2008;31(5):488-92 (Univ. of California, Los Angeles – Unres. Grant) Keyword(s): Radiation, Maculopathy, Retinopathy, Choroidal Melanoma

Differential expression of chemokine receptors on uveal melanoma cells and their metastases

Li H, Alizadeh H, Niederkorn J
Invest Ophthalmol Vis Sci 2008;49:636-643 (Univ. of Texas, Southwestern - Unres. Grant) Keyword(s): Uveal Melanoma

Improvement in visual fields in a patient with melanoma-associated retinopathy treated with intravenous immunoglobulin

Subhadra C, Dudek AZ, Rath PP, Lee MS
J Neuro-Ophthalmol 2008;28:23-26 (Univ. of Minnesota – Unres. Grant) Keyword(s): Melanoma-associated Retinopathy

In-vivo xenograft urine human uveal melanoma model develops hepatic micrometastases

Yang H, Fang G, Huang X, Yu J, Hsieh C, Grossniklaus Hans
Melanoma Research 2008;18:95-103 (Emory Univ. Eye Center - Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Ocular Melanoma

Integrative genomic analysis of aneuploidy in uveal melanoma

Ehlers JP, Worley L, Onken MD, Harbour JW
Clin Cancer Res 2008;14:115-122 (Washington Univ. – Unres. Grant) Keyword(s): Uveal Melanoma

Iridociliary melanoma associated with ocular melanocytosis in a 6-year-old boy

Rahman AM, Augsburger JJ, Corréa ZM
J AAPOS 2008;12(3):312-313 (Univ. of Cincinnati College of Medicine – Unres. Grant) Keyword(s): Pediatric, Melanoma, Melanocytosis

PD-L1: PD-1 interaction contributes to the functional suppression of T-cell responses to human uveal melanoma cells In vitro

Yang W, Chen P, Li H, Alizadeh H, Niederkorn J
Invest Ophthalmol Vis Sci 2008;49:2518-2525 (Univ. of Texas, Southwestern - Unres. Grant) Keyword(s): Uveal Melanoma

Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis

Chang SH, Worley LA, Onken MD, Harbour JW
Melanoma Res 2008;18:191-200 (Washington Univ. – Unres. Grant) Keyword(s): Uveal melanoma

Size overlap between benign melanocytic choroidal nevi and choroidal malignant melanomas

Augsburger JJ, Corrêa ZM, Trichopoulos N, Shaikh A
Investigative Ophthalmology & Visual Science 2008;49(7):2823-2828 (Univ. of Cincinnati College of Medicine – Unres. Grant) Keyword(s): Benign Melanocytic Choroidal Nevi, Choroidal Malignant Melanomas

The relationship between combined positron emission tomography/computed tomography and clinical and light microscope findings in choroidal melanoma

Faia LJ, Pulido JS, Donaldson MJ, Salomao DR, Cameron JD, Mullan B, Gunduz K
Retina 2008;28:763-9 (Mayo Medical School – Unres. Grant) Keyword(s): Melanoma

 

2007 Research Archive

Ciliary body melanoma with limited nodular extrascleral extension and diffuse iris-angle infiltration treated by whole anterior segment plaque radiotherapy

Gray ME, Corrêa ZM, Augsburger JJ, Barrett W
Int Ophthalmol 2007;27:273-6 (Univ. of Cincinnati – Unres. Grant) Keyword(s): Cornea

Cutaneous malignant melanoma metastatic to the vitreous

Prabhakaran VC, Font RL
Retina 2007;27:379-381 (Baylor College of Medicine – Unres. Grant and Sr. Scientific Inv Awd.) Keyword(s): Cancer, Melanoma

Intravitreal bevacizumab treatment for radiation macular edema after plaque radiotherapy for choroidal melanoma

Mason J, Albert M, Persaud T, Vail R
Retina 2007;27:903-907 (Univ. of Alabama – Unres. Grant) Keyword(s): Choroidal Melanoma

Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma

Onken MD, Worley LA, Person E, Char DH, Bowcock AM, Harbour JW
Clin Cancer Res 2007;13:2923-2927 (Washington Univ. - Unres. Grant) Keyword(s): Uveal Melanoma

Massive extraocular extension and parotid lymph node metastasis of uveal melanoma

Harris MS, Harris GJ, Simons KB, Campbell BH
Ophthalmic Plast Reconstr Surg 2007;23:430-432 (Medical College of Wisconsin – Unres. Grant) Keyword(s): Oncology, Orbital Disease

Metastatic cutaneous melanoma involving the retina and vitreous

Khurana RN, Tran VT, Rao NA
Arch Ophthalmol 2007;125:1296-1297 (Univ. of Southern California – Unres. Grant) Keyword(s): Retina

Surveillance of the eye and vision in clinical trials of CP-675,206 for metastatic melanoma

Straatsma BR, Nusinowitz S, Young TA, Gordon LK, Chun MW, Rosen C, Seja E, Economou JS, Glaspy JA, Bozon V, Gomez-Navarro J, Ribas A
Amer J Ophthalmol 2007;143:958-969 (Univ. of California, Los Angeles – Unres. Grant) Keyword(s): Ocular Tumor, Immunotherapy

Syphilitic scleritis and choroidal malignant melanoma of the same eye

Win PH, Gonzales CR, Young T, Yates B, Sarraf D
Semin Ophthalmol 2007;22:193-195 (Univ. of California, Los Angeles - Unres. Grant) Keyword(s): Syphilitic Scleritis, Choroidal Melanoma, Posterior Scleritis

Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal melanoma

Worley LA, Onken MD, Person E, Robirds D, Branson J, Char DH, Perry A, Harbour JW
Clin Cancer Res 2007;13:1466-1471 (Washington Univ. - Unres. Grant) Keyword(s): Uveal Melanoma

Ultrasound biomicroscopy for estimation of tumor thickness for conjunctival melanoma

Ho VH, Prager TC, Diwan H, Prieto V, Esmaeli B
J Clin Ultrasound 2007:35:533-7 (Univ. of Texas, Houston – Unres. Grant) Keyword(s): Melanoma

Uveal melanoma expression of indoleamine 2,3 deoxygenase: Establishment of an immune privileged environment by tryptophan depletion

Chen PW, Mellon JK, Mayhew E, Wang S, He Y-G, Hogan N, Niederkorn J
Exp Eye Res 2007;85:617-625 (Univ. of Texas, Southwestern - Unres. Grant) Keyword(s): Uveal Melanoma

Xanthogranuloma of the iris simulating melanoma in an adult

Sukavatcharin S, Cursino S, Li G, Green RL, Lim JI, Rao NA
Am J Ophthalmol 2007;143:529-531 (Univ. of Southern California – Unres. Grant) Keyword(s): Iris

 

2006 Research Archive

Bruch’s Membrane Abnormalities in Dome-Shaped and Mushroom-Shaped Chroroidal Melanomas

Hainsworth DP, Sommerville DN, Ranson NT, Todd KC, Gigantelli JW
Ann Acad Med Singapore 2006;35:87-88 (Univ. of Missouri – Unres. Grant) Keyword(s): AMD

Conjunctival Melanoma in Children: A Clinicopathologic Study of 2 Cases

Brownstein S, Hamidreza F, Jackson WB, Font RL
Arch Ophthalmol 2006;124:1190-1193 (Baylor College of Medicine – Unres. Grant) Keyword(s): Cornea, Pediatric

Downregulation Of Survivin Expression Enhances Sensitivity Of Cultured Uveal Melanoma Cells To Cisplatin Treatment

Li H, Niederkorn JY, Neelam S, Alizadeh H
Exp Eye Res 2006;83:176-182 (Univ. of Texas Southwestern - Unres. Grant) Keyword(s): Uveal Melanoma and Ocular Tumors

Effect Of An Anti-Cd54 (ICAM-1) Monoclonal Antibody (UV3) On The Growth Of Human Uveal Melanoma Cells Transplanted Heterotopically And Orthotopically In SCID Mice

Wang S, Coleman EJ, Pop LM, Brooks KJ, Vitetta ES, Niederkorn JY
Int J Cancer 2006;118:932-941 (Univ. of Texas Southwestern - Unres. Grant) Keyword(s): Uveal Melanoma, Ocular Oncology and Ocular Immunology

Estimates of Ocular and Visual Retention Following Treatment of Extra-Large Uveal Melanomas by Proton Beam Radiotherapy

Conway RM, Poothullil AM, Daftari IK, Weinberg V, Chung JE, O’Brien JM
Arch Ophthalmol 2006;124:838-843 (Univ. of California, San Francisco – Unres. Grant and Physician-Scientist Awd.) Keywords(s): Ocular Oncology

Functional Gene Expression Analysis Uncovers Phenotypic Switch in Aggressive Uveal Melanomas

Onken MD, Ehlers JP, Worley LA, Makita J, Yokota Y, Harbour JW.
Cancer Res 2006;66(9):4602-9 (Washinton Univ. – Unres. Grant) Keyword(s): Eye Cancer

Prognostic Testing in Uveal Melanoma by Transcriptomic Profiling of Fine Needle Biopsy Specimens

Onken MD, Worley LA, Davila RM, Char DH, Harbour JW
J Mol Diagn. 2006;8:567-73 (Washington Univ. – Unres. Grant) Keyword(s): Eye Cancer

 

2005 Research Archive

Association Between Microarray Gene Expression Signature and Extravascular Matrix Patterns in Primary Uveal Melanomas

Onken MD, Lin AY, Worley LA, Folberg R, Harbour JW
Am J Ophthalmol 2005;140:748-749 (Washington Univ. – Unres. Grant and Physician-Scientist Awd.) Keyword(s): Retina and Retinal Diseases, Ocular Oncology

Cancer-Induced, Immune-Mediated Ocular Degenerations

Thirkill CE
Ocular Immunol Inflammation 2005;13:119-131 (Univ. of California, Davis – Unres. Grant) Keyword(s): Other – Autoimmune Retinopathy, Cancer-Associated Retinopathy, Melanoma Associated Retinopathy

DDEF1 Is Located in an Amplified Region of Chromosome 8q and Is Overexpressed in Uveal Melanoma

Ehlers JP, Worley L, Onken MD, Harbour JW
Clin Cancer Res 2005;11:3609- 3613 (Washington Univ. – Unres. Grant and Physician-Scientist Awd.) Keyword(s): Retina and Retinal Diseases, Ocular Oncology

Functional Analysis of the p53 Pathway to Response to Ionizing Radiation in Uveal Melanoma

Young S, Tran BN, Worley LA, Delston RB, Harbour JW
Invest Ophthalmol Vis Sci 2005;46:1561-1564 (Washington Univ. – Unres. Grant and Physician-Scientist Awd.) Keyword(s): Retina and Retinal Diseases, Ocular Oncology

Incidence of Antiretinal Antibodies in Melanoma: Screening of 77 Serum Samples from 51 Patients with American Joint Committee on Cancer Stage I-IV

Ladewig G, Reinhold U, Thirkill CE, Kerber A, Tilgen W, Pfohler C
Br J Dermatology 2005;152:931-938 (Univ. of California, Davis – Unres. Grant) Keyword(s): Other – Autoimmune Retinopathy, Cancer- Associated Retinopathy, Melanoma Associated Retinopathy

NBS1 Expression as a Prognostic Marker in Uveal Melanoma

Ehlers JP, Harbour JW
Clin Cancer Res 2005;11:1849-1853 (Washington Univ. – Unres. Grant and Physician-Scientist Awd.) Keyword(s): Retina and Retinal Diseases, Ocular Oncology

Outcomes of Iodine 125 Plaque Radiotherapy After Initial Observation of Suspected Small Choroidal Melanomas: A Pilot Study

Sobrin L, Schiffman JC, Markoe AM, Murray TG
Ophthalmology 2005;112:1777-1783 (Univ. of Miami - Unres. Grant) Keyword(s): Retina and Retinal Diseases, Other: Cancer

Resistance and Susceptibility of Human Uveal Melanoma Cells to TRAIL-Induced Apoptosis

Li H, Niederkorn JY, Neelam S, Alizadeh H
Arch Ophthalmol 2005;123:654-661 (Univ. of Texas Southwestern – Unres. Grant) Keyword(s): Retina and Retinal Diseases

Uveal Melanoma: Genetic Aspects

Singh AD, Damato B, Howard P, Harbour JW
Ophthalmol Clin North Am 2005;18:85-97 (Washington Univ. – Unres. Grant and Physician-Scientist Awd.) Keyword(s): Retina and Retinal Diseases, Ocular Oncology