Recent RPB Research & Archives

Welcome to the RPB Research Archive.  Each year, more than 800 scientific studies are published citing RPB grant support, so you should be aware that your search request may produce extensive results, requiring you to scroll through them until you locate a result of specific relevance.  You can click on any of the article titles produced by your search to find an abstract providing an overview of the research.

Search instructions
To search the entire RPB Research Archive for scientific papers on a specific topic, by a specific author, or for bibliographies by eye disease, enter keywords in the box and click Search. 

To browse bibliographies by year, click on the links below and use the search capacity within each downloaded document (Word or PDF) to find specific terms.

61 citations match:

Recent Research

Differential MicroRNA-34a Expression and Tumor Suppressor Function in Retinoblastoma Cells

Clifton L. Dalgard, Marco Gonzalez, Jennifer E. deNiro, and Joan M. O'Brien
Invest. Ophthalmol. Vis. Sci. 2009 50: 4542-4551.

Frontiers in the Management of Retinoblastoma , 25 May 2009

Phoebe Lin, Joan M. O'Brien
American Journal of Ophthalmology
August 2009 (Vol. 148, Issue 2, Pages 192-198)

Gelatinase Expression in Retinoblastoma: Modulation of LHBETATAG Retinal Tumor Development by Anecortave Acetate

M. Livia Bajenaru, Yolanda Piña, Timothy G. Murray, Colleen M. Cebulla, William Feuer, Maria-Elena Jockovich, and Maria-Encarna Marin Castaño
Invest. Ophthalmol. Vis. Sci. 2010 51: 2860-2864.

Lack of Correlation between the Histologic and Magnetic Resonance Imaging Results of Optic Nerve Involvement in Eyes Primarily Enucleated for Retinoblastoma , 22 June 2009

Matthew W. Wilson, Carlos Rodriguez-Galindo, Catherine Billups, Barrett G. Haik, Fred Laningham, Zoltan Patay
Ophthalmology
August 2009 (Vol. 116, Issue 8, Pages 1558-1563)

Subconjunctival Nanoparticle Carboplatin in the Treatment of Murine Retinoblastoma

Shin J. Kang; Chandrasekar Durairaj; Uday B. Kompella; Joan M. O’Brien; Hans E. Grossniklaus
Arch Ophthalmol, Aug 2009; 127: 1043 - 1047.

Sudden Dispersion of Retinoblastoma Shortly after Initial Chemotherapy Treatment , 20 February 2009

Reut Parness-Yossifon, Paul J. Bryar, Joanna L. Weinstein, Divya Srikumaran, Marilyn B. Mets
American Journal of Ophthalmology
May 2009 (Vol. 147, Issue 5, Pages 903-906)

 

2009 Research Archive

AAV-mediated local delivery of interferon-β for the treatment of retinoblastoma in preclinical models

Shih C-S, Lauri N, Holzmacher J, Spence Y, Nathwani AC, Davidoff AM, Dyer MA
Neuromol Med 2009;11:43-52 (Univ. of Tennessee Health Science Center – Unres. Grant and Lew R. Wasserman Merit Awd) Keyword(s): Pediatric, Neuro-Ophthalmology, Retina/ Retinal Diseases

Anterior diffuse retinoblastoma mutational analysis and immunofluorescence staining

Crosby MB, Hubbard GB, Gallie BL, Grossniklaus HE
Arch Pathol Lab Med. 2009;133:1215-1218 (Emory Univ. Eye Center - Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina/Retinal Diseases

Blood vessel maturation in retinoblastoma tumors: spatial distribution of neovessels and mature vessels and its impact on ocular treatment

Piña Y, Boutrid H, Schefler A, Dubovy S, Feuer W, Jockovich ME, Murray TG
Invest Ophthalmol Vis Sci 2009;50(3):1020-1024 (Univ. of Miami, FL - Unres. Grant) Keyword(s): Retina/Retinal Diseases

Differential microRNA-34a expression and tumor suppressor function in retinoblastoma cells

Dalgard CL, Gonzalez M, deNiro JE, O’Brien JM
Invest Ophthalmol Vis Sci 2009;50:4542-4551 (Univ. of California, San Francisco - Unres. Grant) Keyword(s): Genetics, Retinoblastoma

Expression of alpha-crystallin in retinoblastoma

Kase S, Parikh JG, Rao NA
Arch Ophthalmol 2009;127:187-192 (Univ. of Southern California – Unres. Grant) Keyword(s): Pediatric, Retina/Retinal Diseases

Expression of heat shock protein 27 and alpha-crystallins in human retinoblastoma after chemoreduction

Kase S, Parikh JG, Rao NA
Br J Ophthalmol 2009;93:541-544 (Univ. of Southern California – Unres. Grant) Keyword(s): Retina/Retinal Diseases

Expression of the multi-drug resistance proteins and the pregnane X receptor in treated and untreated retinoblastoma

Wilson MW, Fraga CH, Rodriguez-Galindo C, Hagedorn N, Leggas ML, Stewart C
Curr Eye Res 2009;34(5):386-394 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): Neuro-Ophthalmology, Retina/Retinal Disease

Frontiers in the management of retinoblastoma

Lin P, O’Brien JM
Am J Ophthalmol 2009;148:192-198 (Univ. of California, San Francisco - Unres. Grant) Keyword(s): Pediatric, Retinoblastoma

Immunoreactivity of ICAM-1 in human tumors, metastases and normal tissues

Hayes SH, Seigel GM
Int. J Clin Exp Path 2009;2(6):553-560 (State Univ. of New York at Buffalo – Unres. Grant and Sybil Harrington Research Scholar Awd) Keyword(s): Retinoblastoma

Lack of correlation between the histologic and magnetic resonance imaging results of optic nerve involvement in eyes primarily enucleated for retinoblastoma

Wilson MW, Rodriguez-Galindo C, Billups C, Haik BG, Laninham F, Patay Z
Ophthalmology 2009;116(8):1558-1563 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): Pediatric, Retina/Retinal Diseases, Neuro–Ophthalmology

Outcomes of cataract surgery following radiation treatment for retinoblastoma

Payne JF, Hutchinson AK, Hubbard GB, Lambert SR
J AAPOS 2009;13:454-458 (Emory Univ. Eye Center - Unres. Grant) Keyword(s): Cataract, Pediatric

Predictive factors of invasion in eyes with retinoblastoma enucleated after eye salvage treatments

Balaguer J, Wilson MW, Billups CA, Mancini J, Haik BG, Qaddoumi I, Khoury JD, Rodriquez-Galindo C
Pediatr Blood Cancer 2009;52(3):351-356 (Univ. of Tennessee Health Science Center – Unres. Grant) Keyword(s): Pediatric, Retina/Retinal Diseases

Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling

Xu XL, Fang Y, Lee TC, Forrest D, Gregory-Evans C, Almeida D, Liu A, Jhanwar SC, Abramson DH, Cobrinik D
Cell 2009;137:1018-1031 (Univ. of Southern California – Unres. Grant) Keyword(s): Retina/Retinal Diseases

Subconjunctival nanoparticle carboplatin in the treatment of murine retinoblastoma

Kang SJ, Chandrasekar D, Kompella UB, O’Brien JM, Grossniklaus HE
Arch Ophthalmol. 2009;127(8):1043-1047 (Emory Univ. Eye Center - Unres. Grant and Sr. Scientific Inv. Awd) Keyword(s): Retina/Retinal Diseases, Drug Delivery

Sudden dispersion of retinoblastoma shortly after initial chemotherapy treatment

Parness-Yossifon R, Bryar PJ, Weinstein JL, Srikumaran D, Mets MB
Am J Ophthalmol 2009;147:903-906 (Northwestern Univ. – Unres. Grant) Keyword(s): Retina/Retinal Diseases

Use of combination therapy with cisplatin and calcitriol in the treatment of Y-79 human retinoblastoma xenograft model

Kulkarni AD, van Ginkel PR, Darjatmoko SR, Lindstrom MJ, Albert DM
Br J Ophthalmol 2009;93:1105-1108 (Univ. of Wisconsin – Unres. Grant) Keyword(s): Pediatrics, Epidemiology

 

2008 Research Archive

Beta-lapachone inhibits proliferation and induces apoptosis in retinoblastoma cell lines

Shah HR, Conway RM, Van Quill KR, Madigan MC, Howard SA, Qi J, Weinberg V, O'Brien JM
Eye 2008;22:454-460 (Univ. of California, San Francisco – Unres. Grant and Physician-Scientist Awd) Keyword(s): Pediatric, Retinoblastoma

Diffuse infiltrating anterior retinoblastoma in a 16-year-old boy

Shields J, Eagle R, Shields C, Haivala D, Parke D
Retinal Cases & Brief Reports 2008;2:222-224 (Univ. of Oklahoma Health Sciences Center – Unres. Grant) Keyword(s): Tumors

Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma

Dalgard CL, Yang J, Van Quill KR, O’Brien JM
Clin Cancer Res 2008;14:3113-3123 (Univ. of California, San Francisco – Unres. Grant) Keyword(s): Pediatric, Retinoblastoma

Familial retinoblastoma with unilateral and unifocal involvement in 2 families

Sarafzadeh S, Corrêa ZM, Augsburger JJ
Arch Ophthalmol 2008;126(9):1308-1309 (Univ. of Cincinnati College of Medicine – Unres. Grant) Keyword(s): Retinal Blastoma

Heterogeneous tumor vasculature in retinoblastoma: implications for vessel targeting therapy

Jockovich ME, Piña Y, Alegret A, Cebulla C, Feuer W, Murray TG
Retina 2008;28:S81-86 (Univ. of Miami - Unres. Grant) Keyword(s): Pediatric

Lack of effect of SU1498, an inhibitor of vascular endothelial growth factor receptor-2, in a transgenic murine model of retinoblastoma

Cebulla CM, Jockovich ME, Boutrid H, Pina Y, Ruggeri M, Jiao S, Bhattacharya SK, Feuer WJ, Murray TG
Open Ophthalmol J 2008;2:62-67 (Univ. of Miami – Unres. Grant) Keyword(s): Pediatric

Retinoblastoma: One world, one vision

Rodriguez-Galindo C, Wilson MW, Chantada G, Fu L, Qaddoumi I, Antoneli C, Leal-Leal C, Sharma T, Barnoya M, Epelman S, Pizzarello L, Kane JR, Barfield R, Merchant TE, Robison LL, Murphree AL, Chevez-Barrios C, Dyer MA, O’Brien J, Ribeiro RC, Hungerford J, Helveston EM, Haik BG, Wilimas J
Pediatrics 2008;122:e763-e770 (Univ. of Tennessee – Unres. Grant) Keyword(s): Ocular Tumors

Retinoblastoma: one world, one vision

Rodriguez-Galindo C, Wilson MW, Guillermo C, Fu L, Qaddoumi I, Antoneli C, Leal-Leal C, Sharma T, Barnoya M, Epelman S, Pizzarello L, Kane JR, Barfield R, Merchant TE, Robison LL, Murphree AL, Chévez-Barrios P, Dyer MA, O’Brien J, Ribeeiro RC, Hungerford J, Helveston EM, Haid BG, Wilimas J
Pediatrics 2008;122:e763-e770 (Baylor College of Medicine – Unres. Grant) Keyword(s): Pediatric, Retina

Retinoblastoma: one world, one vision

Rodriguez-Galindo C, Wilson MW, Chantada G, Fu L, Qaddoumi I, Antoneli C, Leal-Leal C, Sharma T, Barnoya M, Epelman S, Pizzarello L, Kane JR, Barfield R, Merchant TE, Robison LL, Murphree AL, Chevez-Barrios P, Dyer MA, O'Brien J, Ribeiro RC, Hungerford J, Helveston EM, Haik BG, Wilimas
Pediatrics 2008;122:e763-770 (Univ. of Southern California – Unres. Grant) Keyword(s): Pediatric

Subconjunctival topotecan in fibrin sealant in the treatment of transgenic murine retinoblastoma

Tsui JY, Dalgard C,Van Quill KR, Lee L, Grossniklaus HE, Edelhauser HF, O’Brien JM
Invest Ophthalmol Vis Sci. 2008;49:490-496 (Emory Univ. Eye Center - Unres. Grant) Keyword(s): Drug Delivery, Retinoblastoma

Subconjunctival topotecan in fibrin sealant in the treatment of transgenic murine retinoblastoma

Tsui JY, Dalgard C, Van Quill KR, Lee L, Grossniklaus HE, Edelhauser HF, O’Brien JM
Invest Ophthalmol Vis Sci 2008;49:490-496 (Univ. of California, San Francisco – Unres. Grant) Keyword(s): Pediatric, Retinoblastoma

Targeting hypoxia, a novel treatment for advanced retinoblastoma

Boutrid H, Jockovich ME, Murray TG, Piña Y, Feuer WJ, Lampidis TJ, Cebulla CM
Invest Ophthalmol Vis Sci 2008;49:2799-2805 (Univ. of Miami - Unres. Grant) Keyword(s): Pediatric

Team management, twinning, and telemedicine in retinoblastoma: a 3-tier approach implemented in the first eye salvage program in Jordan

Qaddoumi I, Nawaiseh I, Mehyar M, Razzouk B, Haik BG, Kharma S, Jaradat I, Rodriguez-Galindo C, Wilson MW
Pediatr Blood Cancer 2008;51:241-244 (Univ. of Tennessee – Unres. Grant) Keyword(s): Ocular Tumors

 

2007 Research Archive

Comparison of orbital volumes in enucleated patients with unilateral retinoblastoma: Hydroxyapatite implants versus silicone implants

Lyle CE, Wilson MW, Li C-S, Kaste SC
Ophthal Plast Reconstr Surg 2007;23:393-396 (Univ. of Tennessee – Unres. Grant) Keyword(s): Retinal Oncology

Current status and future perspectives

Rodriguez-Galindo C, Chantada GL, Haik BG, Wilson MW. Treatment of Retinoblastoma
Curr Treat Options Neurol 2007;9:294-307 (Univ. of Tennessee – Unres. Grant) Keyword(s): Retinal Oncology

Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice

Ajioka I, Martina RAP, Bayazitov IT, Donovan S, Johnson DA, Frase S, Cicero SA, Boyd K, Zakharenko SS, Dyer MA
Cell 2007;131:378-390 (Univ. of Tennessee – Unres. Grant and Career Development Awd) Keyword(s): Retinal Oncology

Human embryonic and neuronal stem cell markers in retinoblastoma

Seigel GM, Hackam AS, Ganguly A, Mandell LM, Gonzalez-Fernandez F
Mol Vis. 2007;13:823-32 (Univ. of Miami – Unres. Grant) Keyword(s): Low Vision

Human Embryonic and neuronal stem cell markers in retinoblastoma

Seigel GM, Hackam A, Ganguly A, Gonzalez-Fernandez F
Mol Vis 2007;13:823-832 (State University of New York at Buffalo – Challenge Grant and Sybil B. Harrington Scholar) Keyword(s): Pediatric

Incidence of new tumor formation in patients with hereditary retinoblastoma treated with primary systemic chemotherapy: Is there a preventive effect?

Wilson MW, Haik BG, Billups CA, Rodriguez-Galindo C
Ophthalmology 2007;114:2077-2082 (Univ. of Tennessee – Unres. Grant) Keyword(s): Retinal Oncology

Neuronal differentiation and synaptogenesis in retinoblastoma

Johnson DA, Zhang J, Frase S, Wilson M, Rodriquez-Galindo C, Dyer MA
Cancer Res 2007;67:2701-2711 (Univ. of Tennessee – Unres. Grant and Career Development Awd) Keyword(s): Retinal Oncology

Paclitaxel in the treatment of retinal tumors of LH beta-Tag murine transgenic model of retinoblastoma

Suárez F, Jockovich ME, Hernandez E, Feuer W, Parel JM, Murray TG
Invest Ophthalmol Vis Sci 2007;48:3437-40 (Univ. of Miami – Unres. Grant) Keyword(s): Low Vision

Retinoblastoma tumor vessel maturation impacts efficacy of vessel targeting in the LH(BETA)T(AG) mouse model

Jockovich ME, Bajenaru ML, Piña Y, Suarez F, Feuer W, Fini ME, Murray TG
Invest Ophthalmol Vis Sci 2007:48:2476-82 (Univ. of Miami – Unres. Grant) Keyword(s): Low Vision

 

2006 Research Archive

Immunohistochemical Detection of Multidrug-Resistant Protein Expression in Retinoblastoma Treated by Primary Enucleation

Wilson, MW, Fraga CH, Fuller CE, Rodriquez-Galindo, C, Mancini J, Hagedorn N, Leggas ML. Stewart CF
Inv Ophthalmol Vis Sci 2006;47(4):1269-1273 (Univ. of Tennessee – Unres. Grant) Keyword(s): Ocular Oncology

Inactivation of the p53 Pathway in Retinoblastoma

Laurie NA, Donovan, SL, Shih, C-S, Zhang J, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, Mendrysa SM, Guy, RK, Marine J-C, Jochemsen AG, Dyer MA
Nature 2006;444(2):61-66 (Univ. of Tennessee – Unres. Grant and Career Development Awd) Keyword(s): Ocular Oncology

Iontophoretic Delivery Of Carboplatin In A Murine Model Of Retinoblastoma

Hayden B, Jockovich ME, Murray TG, Kralinger MT, Voigt M, Hernandez E, Feuer W, Parel JM
Invest Ophthalmol Vis Sci 2006;47(9):3717-21 (Univ. of Miami – Unres. Grant) Keyword(s): Ocular Cancer

Ischemic Necrosis and Atrophy of the Optic Nerve after Periocular Carboplatin Injection for Intraocular Retinoblastoma

Schmack I, Hubbard B, Kang SJ, Aaberg TM Jr., Grossniklaus HE
Am J Ophthalmol 2006;142;310-315 (Emory Univ. – Unres. Grant) Keyword(s): Ophthalmic Pathology, Retinoblastoma

Socioeconomic Impact of Modern Multidisciplinary Management of Retinoblastoma

Wilson MW, Haik BG, Rodriquez-Galindo C
J Am Acad Pediatrics 2006;118:e331-e336 (Univ. of Tennessee – Unres. Grant) Keyword(s): Ocular Oncology

The Wnt Signaling Pathway has Tumor Suppressor Properties in Retinoblastoma

Tell S, Yi H, Jockovich ME, Murray TG, Hackam AS
Biochem Biophys Res Commun. 2006 13;349(1):261-9 (Univ.of Miami - Unres. Grant and Career Development Awd) Keyword(s): Ocular Cancer

 

2005 Research Archive

Cancer Stem Cell Characteristics in Retinoblastoma

Seigel GM, Campbell LM, Narayan M, Gonzalez-Fernandez F
Mol Vis 2005;11:729-737 (SUNY, Buffalo – Challenge Grant and Sybil B. Harrington Scholar) Keyword(s): Retina and Retinal Diseases

Combretastatin A-4 Prodrug in the Treatment of a Murine Model of Retinoblastoma

Escalona-Benz E, Jockovich ME, Murray TG, Hayden B, Hernandez E, Feuer W, Windle JJ
Invest Ophthalmol Vis Sci 2005;46:8-11 (Univ. of Miami – Unres. Grant) Keyword(s): Retina and Retinal Diseases, Other Cancer

Cyclosporin A Inhibits Calcineurin/Nuclear Factor of Activated T-Cells Signaling and Induces Apoptosis in Retinoblastoma Cells

Eckstein LA, Van Quill KR, Bui SK, Uusitalo MS, O’Brien JM
Invest Ophthalmol Vis Sci 2005;46:782-790 (Univ. of California, San Francisco – Unres. Grant and Physician-Scientist Awd.) Keyword(s): Other: Ocular Oncology

Effect on Ocular Survival of Adding Early Intensive Focal Treatments to a Two-Drug Chemotherapy Regimen in Patients with Retinoblastoma

Wilson MW, Haik BG, Liu T, Merchant TE, Rodriguez-Galindo C
Am J Ophthalmol 2005;140:397-406 (Univ. of Tennessee – Unres. Grant) Keyword(s): Retina and Retinal Diseases

Effects of Celecoxib in Human Retinoblastoma Cell Lines and in a Transgenic Murine Model of Retinoblastoma

Tong CT, Howard SA, Shah HR, Van Quill KR, Lin ET, Grossniklaus HE, O’Brien JM
Br J Ophthalmol 2005;89:1217-1220 (Emory Univ. – Unres. Grant and Physician-Scientist Awd.) Keyword(s): Celecoxib, Retinal Blastoma

Effects of Celecoxib in Human Retinoblastoma Cell Lines and in a Transgenic Murine Model of Retinoblastoma

Tong CT, Howard SA, Shah HR, Van Quill KR, Lin ET, Grossniklaus HE, O’Brien JM
Br J Ophthalmol 2005;89:1217-1220 (Univ. of California, San Francisco – Unres. Grant and Physician-Scientist Awd.) Keyword(s): Other: Ocular Oncology

Retinoblastoma and Hypochondroplasia: A Case Report of Two Germline Mutations Rising Simultaneously

Tsai T, Gombos D, Cronin JE, Muthialu A, Fulton L, Conway RM, O'Brien JM
Ophthalmic Genet 2005;26:107-110 (Univ. of California, San Francisco - Unres. Grant) Keyword(s): Pediatric, Other: Ocular Oncology

The Search for the Retinoblastoma Cell of Origin

Dyer MA, Bremner R
Nature Rev 2005;5:91-101 (Univ. of Tennessee – Unres. Grant) Keyword(s): Other: Gene Expression

Topotecan Combination Chemotherapy in Two New Rodent Models of Retinoblastoma

Laurie NA, Gray JK, Zhang J, Leggas M, Rellling M, Egorin M, Stewart C, Dyer MA
Clin Cancer Res 2005;11:7569-7578 (Univ. of Tennessee – Unres. Grant) Keyword(s): Retina and Retinal Diseases