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Research to Prevent Blindness

Research Database

University of Wisconsin Research, funded by RPB in 2014 matching Departmental Grant

53 Citations, Sorted by Month and Year

November, 2014
Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration.

Ratnapriya R, Zhan X, Fariss RN, et al

Hum Mol Genet. 2014 Nov 1;23(21):5827-5837

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

October, 2014
al.

Kanavi MR, Darjatmoko S, Wang S, et

The sustained delivery of resveratrol or a defined grape powder inhibits new blood vessel formation in a mouse model of choroidal neovascularization. Molecules 2014 Oct;19(11):17578-603

University of Wisconsin - Departmental Grant

Keywords: AMD, Nanotechnology/Drug Delivery

al.

Song W, Wei Q, Liu W, et

A combined method to quantify the retinal metabolic rate of oxygen using photoacoustic ophthalmoscopy and optical coherence tomography. Sci Rep. 2014 Oct 6;4:6525

University of Wisconsin - Departmental Grant

Keywords: Diabetic Retinopathy, Imaging

Cigarette smoking and the natural history of age-related macular degeneration: the beaver dam eye study.

Myers CE, Klein BE, Gangnon R, Sivakumaran TA, Iyengar SK, Klein R

Ophthalmology. 2014 Oct;121(10):1949-1955

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

Cost-Effectiveness of fluocinolone acetonide implant versus systemic therapy for noninfectious intermediate, posterior, and panuveitis.

Sugar EA, Holbrook JT, Kempen JH, et al

Ophthalmology. 2014 Oct;121(10):1855-1862

University of Wisconsin - Departmental Grant

Keyword: Uveitis/Infectious Diseases

The trabecular meshwork in normal eyes and in exfoliation glaucoma.

Rasmussen CA, Kaufman PL

J Glaucoma. 2014 Oct-Nov:S15-19

University of Wisconsin - Departmental Grant

Keyword: Glaucoma

September, 2014
Effect of doxycycline vs placebo on retinal function and diabetic retinopathy progression in mild to moderate nonproliferative diabetic retinopathy: a randomized proof-of-concept clinical trial.

Scott IU, Jackson GR, Quillen DA, Klein R, Liao J, Gardner TW

JAMA Ophthalmol. 2014 Sep;132(9):1137-1142

University of Wisconsin - Departmental Grant

Keywords: Diabetic Retinopathy, Epidemiology

Latrunculin B Reduces intraocular pressure in human ocular hypertension and primary open-angle glaucoma.

Rasmussen CA, Kaufman PL, Ritch R, Haque R, Brazzell RK, Vittitow JL

Transl Vis Sci Technol. 2014 Sep;3(5):1

University of Wisconsin - Departmental Grant

Keyword: Glaucoma

Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium.

Klein R, Myers CE, Buitendijk GH, et al

Am J Ophthalmol. 2014 Sep;158(3):513-524

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

Oligonucleotides designed to inhibit TLR9 block herpes simplex virus type 1 infection at multiple steps.

Sauter MM, Gauger JJ, Brandt CR

Antiviral Res. 2014 Sep;109:83-96

University of Wisconsin - Departmental Grant

Keyword: Uveitis/Infectious Diseases

Peptide therapeutics for treating ocular surface infections.

Brandt CR

J Ocul Pharmacol Ther. 2014 Sep 24

University of Wisconsin - Departmental Grant

Keyword: Uveitis/Infectious Diseases

Prospects for lentiviral vector mediated prostaglandin f synthase gene delivery in monkey eyes in vivo.

Lee ES, Rasmussen CA, Filla MS, et al

Curr Eye Res. 2014 Sep;39(9):859-870

University of Wisconsin - Departmental Grant

Keywords: Glaucoma, Gene Research/Therapy

Sunlight exposure, pigmentation, and incident age-related macular degeneration.

Klein BE, Howard KP, Iyengar SK, et al

Invest Ophthalmol Vis Sci. 2014 Sep;55(9):5855-5861

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

The Gos28 SNARE mediates intra-golgi transport of rhodopsin and is required for photoreceptor survival.

Rosenbaum EE, Vasiljevic E, Cleland SC, Flores C, Colley NJ

J Biol Chem. 2014 Sep 26

University of Wisconsin - Departmental Grant

Keywords: Retinitis Pigmentosa, AMD

August, 2014
Neuroprotective effects of C3 exoenzyme in excitotoxic retinopathy.

Wang Y, Yang Q, Guo L, et al

Exp Eye Res. 2014 Aug;125:128-134

University of Wisconsin - Departmental Grant

Keywords: Glaucoma, Other: Neuro-Inflammation

The association of taste with change in adiposity-related health measures.

Fischer ME, Cruickshanks KJ, Schubert CR, et al

J Acad Nutr Diet. 2014 Aug;114(8):1195-1202

University of Wisconsin - Departmental Grant

Keyword: Epidemiology

Vasodilators, blood pressure-lowering medications, and age-related macular degeneration: the beaver dam eye study.

Klein R, Myers CE, Klein BE

Ophthalmology. 2014 Aug;121(8):1604-1611

University of Wisconsin - Departmental Grant

Keyword: AMD

July, 2014
A detailed three-step protocol for live imaging of intracellular traffic in polarized primary porcine rpe monolayers.

Toops KA, Tan LX, Lakkaraju A

Exp Eye Res. 2014 Jul;124:74-85

University of Wisconsin - Departmental Grant

Keyword: AMD

CD40 promotes the development of early diabetic retinopathy in mice.

Portillo JA, Greene JA, Okenka G, Miao Y, Sheibani N, Kern TS, Subauste CS

Diabetologia. 2014 Jul 12

University of Wisconsin - Departmental Grant

Keyword: Diabetic Retinopathy

High glucose alters retinal astrocytes phenotype through increased production of inflammatory cytokines and oxidative stress.

Shin ES, Huang Q, Gurel Z, Sorenson CM, Sheibani N

PLoS One. 2014 Jul 28;9(7):e103148

University of Wisconsin - Departmental Grant

Keyword: Diabetic Retinopathy

Patient-reported outcomes: comprehensive analysis for the oculofacial clinician.

Ramey NA, Butt Z, Burkat CN, Rose JG, Lucarelli MJ

Ophthal Plast and Reconstr Surg. 2014 Jul-Aug;30(4):279-289

University of Wisconsin - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

June, 2014
Relation of smoking, drinking, and physical activity to changes in vision over a 20-year period: the beaver dam eye study.

Klein R, Lee KE, Gangnon RE, Klein BE

Ophthalmology. 2014 Jun;121(6):1220-1228

University of Wisconsin - Departmental Grant

Keywords: Cataract, Cornea, Retina/Retinal Diseases, Epidemiology

May, 2014
Angiolymphoid hyperplasia with eosinophilia of the orbit and ocular adnexa: report of 5 cases.

Azari AA, Kanavi MR, Lucarelli M, et al

JAMA Ophthalmol. 2014 May;132(5):633-636

University of Wisconsin - Departmental Grant

Keywords: Oculoplastic, Ocular Oncology/Pterygium

Identification of O-GlcNAc modification targets in mouse retinal pericytes: Implication of p53 in pathogenesis of diabetic retinopathy.

Gurel Z, Zaro BW, Pratt MR, Sheibani N

PLoS One. 2014 May 1;9(5):e95561

University of Wisconsin - Departmental Grant

Keywords: Diabetic Retinopathy, Gene Research/Therapy

Mutations in four glycosyl hydrolases reveal a highly coordinated pathway for rhodopsin biosynthesis and N-glycan trimming in drosophila melanogaster.

Rosenbaum EE, Vasiljevic E, Brehm KS, Colley NJ

PLoS Genet. 2014 May;10(5):e1004349

University of Wisconsin - Departmental Grant

Keywords: Retinitis Pigmentosa, AMD

Prognostic implications of microvascular and macrovascular abnormalities in older adults: Cardiovascular health study.

Kim DH, Grodstein F, Newman AB, et al

J Gerontol A Biol Sci Med Sci. 2014 May 26

University of Wisconsin - Departmental Grant

Keywords: Diabetic Retinopathy, Epidemiology

The benefits, risks, and efficacy of strabismus surgery in adults.

Kushner BJ

Optom Vis Sci. 2014 May;91(5):e102-109

University of Wisconsin - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

The occurrence and proposed significance of schnabel cavernous degeneration in uveal melanoma.

Kanavi MR, Azari AA, Potter HD, Lee V, Albert DM

JAMA Ophthalmol. 2014 May;132(5):600-604

University of Wisconsin - Departmental Grant

Keyword: Ocular Oncology/Pterygium

April, 2014
Dry eye in the beaver dam offspring study: prevalence, risk factors, and health-related quality of life.

Paulsen AJ, Cruickshanks KJ, Fischer ME, et al

Am J Ophthalmol. 2014 Apr;157(4):799-806

University of Wisconsin - Departmental Grant

Keywords: Dry Eye, Epidemiology

Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the beaver dam eye study.

Klein R, Myers CE, Cruickshanks KJ, et al

JAMA Ophthalmol. 2014 Apr 1;132(4):446-455

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

Measures of body shape and adiposity as related to incidence of age-related eye diseases: observations from the Beaver Dam Eye Study.

Howard KP, Klein BE, Lee KE, Klein R

Invest Ophthalmol Vis Sci. 2014 Apr;55(4):2592-2598

University of Wisconsin - Departmental Grant

Keywords: Retina/Retinal Diseases, Epidemiology

Serum carboxymethyllysine, an advanced glycation end product, and age-related macular degeneration: the age, gene/environment susceptibility-reykjavik study.

Semba RD, Cotch MF, Gudnason V, et al

JAMA Ophthalmol. 2014 Apr 1;132(4):464-470

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

March, 2014
Application of canaloplasty in glaucoma gene therapy: where are we?

Aktas Z, Tian B, McDonald J, et al

J Ocul Pharmacol ther. 2014 Mar-Apr;30(2-3):277-282

University of Wisconsin - Departmental Grant

Keyword: Glaucoma

Benzalkonium chloride and glaucoma.

Rasmussen CA, Kaufman PL, Kiland JA

J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):163-169

University of Wisconsin - Departmental Grant

Keyword: Glaucoma

Misclassification can explain most apparent regression of age-related macular degeneration: results from multistate models with misclassification.

Gangnon RE, Lee KE, Klein BE, Iyengar SK, Sivakumaran TA, Klein R

Invest Ophthalmol Vis Sci. 2014 Mar;55(3):1780-1786

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

Orbital osteoma: clinical features and management options.

Wei LA, Ramey NA, Durairaj VD, et al

Ophthal Plast and Reconstr Surg. 2014 Mar-Apr;30(2):168-174

University of Wisconsin - Departmental Grant

Keyword: Oculoplastic

Spontaneous superior ophthalmic vein thrombosis: a rare entity with potentially devastating consequences.

Lim LH, Scawn RL, Whipple KM, et al

Eye (Lond). 2014 Mar;28(3):348-351

University of Wisconsin - Departmental Grant

Keywords: Retinal Vein and Artery Occlusion, Oculoplastic

Statin use and cataracts.

Klein BE, Lee KE, Klein R

JAMA Ophthalmol. 2014 Mar;132(3):366-367

University of Wisconsin - Departmental Grant

Keyword: Cataract

February, 2014
Harmonizing the classification of age-related macular degeneration in the three-continent AMD consortium.

Klein R, Meuer SM, Myers CE, et al

Ophthalmic Epidemiol. 2014 Feb;21(1):14-23

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

Hearing impairment and retirement.

Fischer ME, Cruickshanks KJ, Pinto A, Klein BE, Klein R, Dalton DS

J Am Acad Audiol. 2014 Feb;25(2):164-170

University of Wisconsin - Departmental Grant

Keyword: Epidemiology

Matricellular protein thrombospondins: Influence on ocular angiogenesis, wound healing and immuneregulation.

Masli S, Sheibani N, Cursiefen C, Zieske J

Curr Eye Res. 2014 Feb 21

University of Wisconsin - Departmental Grant

Keyword: Diabetic Retinopathy

January, 2014
Changing incidence of lens extraction over 20 years: the beaver dam eye study.

Klein BE, Howard KP, Lee KE, Klein R

Ophthalmology. 2014 Jan;121(1):5-9

University of Wisconsin - Departmental Grant

Keyword: Cataract

Cross-sectional associations of medication and supplement use with retinal vascular diameter in the beaver dam eye study.

Howard KP, Klein BE, Dreyer JO, Danforth LG, Klein R

JAMA Ophthalmol. 2014 Jan;132(1):23-31

University of Wisconsin - Departmental Grant

Keywords: Diabetic Retinopathy, Epidemiology

Diabetes and retinal vascular dysfunction.

Shin ES, Sorenson CM, Sheibani N

J Ophthalmic Vis Res. 2014; 9 (3): 362-373

University of Wisconsin - Departmental Grant

Keyword: Diabetic Retinopathy

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs.

Zhong X, Gutierrez C, Xue T, et al

Nature Commun. 2014;5:4047

University of Wisconsin - Departmental Grant

Keywords: Stem Cell Research/Therapy, AMD

Genetic evidence for role of carotenoids in age-related macular degeneration in the carotenoids in age-related eye disease study (careds).

Meyers KJ, Mares JA, Igo RP, Jr, et al

Invest Ophthalmol Vis Sci. 2014 Jan;55(1):587-599

University of Wisconsin - Departmental Grant

Keywords: AMD, Epidemiology

Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury.

Schmitt HM, Pelzel HR, Schlamp CL, Nickells RW

Mol Neurodegener. 2014;9:39

University of Wisconsin - Senior Scientific Investigator Award - Nickells, Robert W / PhD Departmental Grant

Keywords: Glaucoma, Gene Research/Therapy

Patient satisfaction and clinical outcomes with laser refractive surgery performed by surgeons in training.

Nehls SM, Ghoghawala SY, Hwang FS, Azari AA

J Cataract Refract Surg. 2014

University of Wisconsin - Departmental Grant

Keywords: Myopia, Presbyopia

Place-based exposure and cataract risk in the beaver dam cohort.

McElroy JA, Klein BE, Lee KE, Howard KP, Klein R

J Environ Health. 2014 Jan-Feb;76(6):34-40

University of Wisconsin - Departmental Grant

Keywords: Cataract, Epidemiology

Quantifying optic nerve axons in a cat glaucoma model by a semi-automated targeted counting method.

Teixeira LBC, Buhr KA, Bowie O, Duke FD, Nork TM, Dubielzig RR, McLellan GJ

Mol. Vision. 2014;20:376-385

University of Wisconsin - Departmental Grant

Keyword: Glaucoma

Should I stay or should I go? Trafficking of sub-lytic MAC in the retinal pigment epithelium.

Lakkaraju A, Toops KA, Xu J

Adv Exp Med Biol. 2014;801:267-274

University of Wisconsin - Departmental Grant

Keyword: AMD

Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage.

Dietz JA, Maes ME, Huang S, et al

PloS One. 2014;9(4):e93564

University of Wisconsin - Departmental Grant

Keywords: Glaucoma, Gene Research/Therapy

STAT1-mediated bim expression promotes the apoptosis of retinal pericytes under high glucose conditions.

Shin ES, Huang Q, Gurel Z, Palenski TL, Zaitoun I, Sorenson CM, Sheibani N

Cell Death Dis. 2014 Jan 9;5

University of Wisconsin - Departmental Grant

Keyword: Diabetic Retinopathy

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