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Research to Prevent Blindness

Research Database

Washington University Research, funded by RPB in 2014 matching Departmental Grant

21 Citations, Sorted by Month and Year

November, 2014
The transcription factor GTF2IRD1 regulates the topology and function of photoreceptors by modulating photoreceptor gene expression across the retina.

Masuda T, Zhang X, Berlinicke C, Wan J, Yerrabelli A, Conner EA, Kjellstrom S, Bush R, Thorgeirsson SS, Swaroop A, Chen S, Zack DJ

J Neurosci. 2014 Nov 12;34(46):15356-68

Washington University - Departmental Grant

Keywords: Retina/Retinal Diseases, Macular Dystrophy, Gene Research/Therapy

October, 2014
Mechanisms of blindness: Animal models provide insight into distinct CRX-associated retinopathies.

Tran NM, Chen S

Dev Dyn. 2014 Oct;243(10):1153-66

Washington University - Departmental Grant

Keywords: Retina/Retinal Diseases, Macular Dystrophy, Gene Research/Therapy

Retrograde plasticity and differential competition of bipolar cell dendrites and axons in the developing retina.

Johnson RE, Kerschensteiner D

Curr Biol. 2014 Oct 6;24(19):2301-6

Washington University - Career Development Award - Kerschensteiner, Daniel / MD Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Retinal Development

September, 2014
Endothelial cell FGF signaling is required for injury response but not for vascular development or homeostasis.

Oladipupo SS, Smith C, Santeford A, Park C, Sene A, Wiley LA, Osei-Owusu P, Hsu J, Zapata N, Liu F, Lavine KJ, Blumer KJ, Choi K, Apte RS, Ornitz DM

Pro Natl Acad Sci. 2014 Sep; 111(37):13379-84

Washington University - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases, Retinitis Pigmentosa, Stem Cell Research/Therapy

August, 2014
Chromophore supply rate-limits mammalian photoreceptor dark adaptation.

Wang JS, Nymark S, Frederiksen R, Estevez ME, Shen SQ, Corbo JC, Cornwall MC, Kefalov VJ

J Neurosci. 2014 Aug; 34:11212-11221

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

July, 2014
FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands.

Chen Z, Huang J, Liu Y, Dattilo LK, Huh SH, Ornitz D, Beebe DC

Development. 2014 Jul;141(13):2691-701

Washington University - Departmental Grant

Keywords: Dry Eye, Cornea, Gene Research/Therapy

May, 2014
Bai.

Beebe D, Shui YB, Siegfried C, Holekamp B and F

Preserve the (intraocular) environment: The importance of maintaining normal oxygen gradients in the eye. Japanese J Ophthalmol. 2014 May;58(3):225-31

Washington University - Departmental Grant

Keywords: Cataract, Glaucoma

Retaining clinician-scientists: Nature versus nurture.

Culican SM, Rupp JD, Margolis TP

Invest Ophthalmol Vis Sci. 2014 May 27;55(5):3219-22

Washington University - Departmental Grant

Keywords: Other: Career Development, Other: Education

April, 2014
Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles.

Pham CT, Thomas DG, Beiser J, Mitchell LM, Huang JL, Senpan A, Hu G, Gordon M, Baker NA, Pan D, Lanza GM, Hourcade DE

Nanomedicine. 2014 Apr;10(3):651-60

Washington University - Departmental Grant

Keyword: Nanotechnology/Drug Delivery

In vivo substrates of the lens molecular chaperones αA- and αB-crystallin.

Andley UP, Malone JP, Townsend RR

PLoS One. 2014 Apr 23;9(4):e95507

Washington University - Departmental Grant

Keyword: Cataract

Temporal and tissue-specific disruption of LINC complexes in vivo.

Razafsky D, Hodzic D

Genesis. 2014 Apr;52(4):359-65

Washington University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

March, 2014
Eyeballing cholesterol efflux and macrophage function in disease pathogenesis.

Sene A, Apte RS

Trends Endocrinol Metab. 2014 Mar;25(3):107-14

Washington University - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases, Retinitis Pigmentosa, Stem Cell Research/Therapy

February, 2014
Mechanistically distinct mouse models for CRX-associated retinopathy.

Tran NM, Zhang A, Zhang X, Huecker JB, Hennig AK, and Chen S

PLoS Genet. 2014 Feb;10(2):e1004111

Washington University - Departmental Grant

Keywords: Retina/Retinal Diseases, Macular Dystrophy, Gene Research/Therapy

January, 2014
DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.

Sundermeier TR, Zhang N, Vinberg F, Mustafi D, Kohno H, Golczak M, Bai X, Maeda A, Kefalov VJ, Palczewski K

FASEB J. 2014;28:3780-3791

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

Enzymatic degradation identifies components responsible for the structural properties of the vitreous body.

Filas BA, Zhang Q, Okamoto RJ, Shui YB, Beebe DC

Invest Ophthalmol Vis Sci. 2014 Jan 3;55(1):55-63

Washington University - Departmental Grant

Keywords: Retinal Detachment, Retina/Retinal Diseases, Cataract

Ex Vivo ERG analysis of photoreceptors using an In Vivo ERG system.

Vinberg F, Kolesnikov AV, Kefalov VJ

Vision Res. 2014;101C:108-117

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma.

Bennett TM, Mackay DS, Siegfried CJ, Shiels A

PLoS One. 2014; 9:e104000

Washington University - Departmental Grant

Keywords: Cataract, Glaucoma

Nuclear envelope in nuclear positioning and cell migration.

Razafsky D, Wirtz D, Hodzic D

Adv Exp Med Biol. 2014;773:471-90

Washington University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.

Sakami S, Kolesnikov AV, Kefalov VJ, Palczewski K

Hum Mol Genet. 2014;23:1723-1741

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

R9AP overexpression alters phototransduction kinetics in iCre75 mice.

Sundermeier TR, Vinberg F, Mustafi D, Bai X, Kefalov VJ, Palczewski K

Invest Ophthalmol Vis Sci. 2014;55:1339-47

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

Science research conference on biology and chemistry of vision.

Kefalov VJ, Arshavsky VY

FASEB J. 2014;28:2395-2397

Washington University - Departmental Grant

Keyword: Retina/Retinal Diseases

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