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Research to Prevent Blindness

Research Database

Tufts University Research, funded by RPB from 2011-2014 matching Departmental Grant

130 Citations, Sorted by Month and Year

December, 2014
Glycobiology of ocular angiogenesis.

Markowska AI, Cao Z, Panjwani N

Glycobiology. 2014 Dec;24(12):1275-82

Tufts University - Departmental Grant

Keywords: Cornea, Retina/Retinal Diseases

October, 2014
Genetic variants in the complement system predisposing to age-related macular degeneration: A review.

Schramm EC, Clark SJ, Triebwasser MP, Raychaudhuri S, Seddon JM, Atkinson JP

Mol Immunol. 2014 Oct;61(2):118-25

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy

Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration.

Yu Y, Triebwasser MP, Wong EK, Schramm EC, Thomas B, Reynolds R, Mardis ER, Atkinson JP, Daly M, Raychaudhuri S, Kavanagh D, Seddon JM

Hum Mol Genet. 2014 Oct 1;23(19):5283-93

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy

September, 2014
Fuchs endothelial corneal dystrophy: Clinical characteristics of surgical and nonsurgical patients.

Goldberg RA, Raza S, Walford E, Feuer WJ, Goldberg JL

Clin Ophthalmol. 2014 Sep 9;8:1761-6

Tufts University - Departmental Grant

Keyword: Cornea

Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy.

Wong JR, Morton LM, Tucker MA, Abramson DH, Seddon JM, Sampson JN, Kleinerman RA

J Clin Oncol. 2014 Sep 2

Tufts University - Departmental Grant

Keyword: Ocular Oncology

Role of galectins in re-epithelialization of wounds.

Panjwani N

Ann Transl Med. 2014 Sep;2(9):89,5839.2014.09.09

Tufts University - Departmental Grant

Keyword: Cornea

Spectral-domain and swept-source OCT imaging of asteroid hyalosis: A case report.

Alasil T, Adhi M, Liu JJ, Fujimoto JG, Duker JS, Baumal CR

Ophthalmic Surg Lasers Imaging Retina. 2014 Sep 23:1-3

Tufts University - Departmental Grant

Keywords: Diabetic Retinopathy, Imaging, Retina/Retinal Diseases

July, 2014
Enhanced vitreous imaging in healthy eyes using swept source optical coherence tomography.

Liu JJ, Witkin AJ, Adhi M, Grulkowski I, Kraus MF, Dhalla AH, Lu CD, Hornegger J, Duker JS, Fujimoto JG

PLoS One. 2014 Jul 18;9(7):e102950

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Molecular basis for MMP9 induction and disruption of epithelial cell-cell contacts by galectin-3.

Mauris J, Woodward AM, Cao Z, Panjwani N, Argueso P

J Cell Sci. 2014 Jul 15;127(Pt 14):3141-8

Tufts University - Departmental Grant

Keyword: Cornea

Optical coherence tomography in the preoperative and postoperative management of macular hole and epiretinal membrane.

Goldberg RA, Waheed NK, Duker JS

Br J Ophthalmol. 2014 Jul;98(Suppl 2):ii20-3

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Optical coherence tomography shows retinal abnormalities associated with optic nerve disease.

Tawse KL, Hedges TR,3rd, Gobuty M, Mendoza-Santiesteban C

Br J Ophthalmol. 2014 Jul;98 Suppl 2:ii30-3

Tufts University - Departmental Grant

Keywords: Retina/Retinal Diseases, Neuro-Ophthalmology

Quantitative 3D-OCT motion correction with tilt and illumination correction, robust similarity measure and regularization.

Kraus MF, Liu JJ, Schottenhamml J, Chen CL, Budai A, Branchini L, Ko T, Ishikawa H, Wollstein G, Schuman J, Duker JS, Fujimoto JG, Hornegger J

Biomed Opt Express. 2014 Jul 11;5(8):2591-613

Tufts University - Departmental Grant

Keywords: Imaging, Glaucoma

Regression of choroidal metastasis from breast carcinoma treated with gamma knife radiosurgery.

Lally DR, Duker JS, Mignano JE, Martin S, Witkin AJ

JAMA Ophthalmol. 2014 Jul 17

Tufts University - Departmental Grant

Keyword: Ocular Oncology

June, 2014
Allele-specific methylation occurs at genetic variants associated with complex disease.

Hutchinson JN, Raj T, Fagerness J, Stahl E, Viloria FT, Gimelbrant A, Seddon J, Daly M, Chess A, Plenge R

PLoS One. 2014 Jun 9;9(6):e98464

Tufts University - Departmental Grant

Keyword: Gene Research/Therapy

Choroidal analysis in healthy eyes using swept-source optical coherence tomography compared to spectral domain optical coherence tomography.

Adhi M, Liu JJ, Qavi AH, Grulkowski I, Lu CD, Mohler KJ, Ferrara D, Kraus MF, Baumal CR, Witkin AJ, Waheed NK, Hornegger J, Fujimoto JG, Duker JS

Am J Ophthalmol. 2014 Jun;157(6):1272-81.e1

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Progressive outer retinal necrosis secondary to herpes simplex virus type 2.

Bartolini CE, Liang MC, Goldberg RA, Goldman DR, Witkin SR, Duker JS

Ophthalmic Surg Lasers Imaging Retina. 2014 Jun 4:1-2

Tufts University - Departmental Grant

Keywords: Retina/Retinal Diseases, Uveitis/Infectious Diseases

Retinal telangiectasis detected during a vision screening examination in a child with hearing loss led to the diagnosis of facioscapulohumeral muscular dystrophy.

Lee GD, Chen VM, Barnes AC, Goldman DR, Duker JS

J AAPOS. 2014 Jun;18(3):303-5

Tufts University - Departmental Grant

Keywords: Retina/Retinal Diseases, Imaging

Retinopathy of prematurity and brain damage in the very preterm newborn.

Allred EN, Capone A,Jr, Fraioli A, Dammann O, Droste P, Duker J, Gise R, Kuban K, Leviton A, O'Shea TM, Paneth N, Petersen R, Trese M, Stoessel K, Vanderveen D, Wallace DK, Weaver G

J AAPOS. 2014 Jun;18(3):241-7

Tufts University - Departmental Grant

Keyword: Retina/Retinal Diseases

Subretinal drusenoid deposits associated with complement-mediated IgA nephropathy.

Lally DR, Baumal C

JAMA Ophthalmol. 2014 Jun;132(6):775-7

Tufts University - Departmental Grant

Keywords: Retina/Retinal Diseases, Imaging

Traumatic choroidal rupture with submacular hemorrhage treated with pneumatic displacement.

Goldman DR, Vora RA, Reichel E

Retina. 2014 Jun;34(6):1258-60

Tufts University - Departmental Grant

Keywords: Retina/Retinal Diseases, Imaging

May, 2014
AAV-mediated expression of human PRELP inhibits complement activation, choroidal neovascularization and deposition of membrane attack complex in mice.

Birke MT, Lipo E, Adhi M, Birke K, Kumar-Singh R

Gene Ther. 2014 May;21(5):507-13

Tufts University - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases, Gene Research/Therapy

Collaborative retrospective macula society study of photodynamic therapy for chronic central serous chorioretinopathy.

Lim JI, Glassman AR, Aiello LP, Chakravarthy U, Flaxel CJ, Spaide RF, Macula Society CSC Collaborative Study Group, Research and Education Committee and Website Committee

Ophthalmology. 2014 May;121(5):1073-8

Tufts University - Departmental Grant

Keywords: Retina/Retinal Diseases, Imaging

Macular choroidal thickness profile in a healthy population measured by swept-source optical coherence tomography.

Ruiz-Medrano J, Flores-Moreno I, Pena-Garcia P, Montero JA, Duker JS, Ruiz-Moreno JM

Invest Ophthalmol Vis Sci. 2014 May 20;55(6):3532-42

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Nature and nurture- genes and environment- predict onset and progression of macular degeneration.

Sobrin L, Seddon JM

Prog Retin Eye Res. 2014 May;40:1-15

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy

Pan retinal photocoagulation for proliferative diabetic retinopathy: Pattern scan laser versus argon laser.

Alasil T, Waheed NK

Curr Opin Ophthalmol. 2014 May;25(3):164-70

Tufts University - Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

April, 2014
Leaking choroidal nevus treated with focal laser photocoagulation.

Goldman DR, Barnes AC, Vora RA, Duker JS

Retin Cases Brief Rep. 2014 Spring;8(2):135-7

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Neuro-ophthalmic effects of stenting across the ophthalmic artery origin in the treatment of intracranial aneurysms.

Heller RS, Lawlor CM, Hedges TR,3rd, Bababekov YJ, Safain MG, Malek AM

J Neurosurg. 2014 Apr 11

Tufts University - Departmental Grant

Keyword: Neuro-Ophthalmology

Vision loss after intravitreal ocriplasmin: Correlation of spectral-domain optical coherence tomography and electroretinography.

Tibbetts MD, Reichel E, Witkin AJ

JAMA Ophthalmol. 2014 Apr 1;132(4):487-90

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

March, 2014
Congenital simple hamartoma of the retinal pigment epithelium: Clinical, optical coherence tomography, and histopathological correlation.

Barnes AC, Goldman DR, Laver NV, Duker JS

Eye (Lond). 2014 Mar 7

Tufts University - Departmental Grant

Keywords: Retina/Retinal Diseases, Imaging

Direct comparison of spectral-domain and swept-source OCT in the measurement of choroidal thickness in normal eyes.

Copete S, Flores-Moreno I, Montero JA, Duker JS, Ruiz-Moreno JM

Br J Ophthalmol. 2014 Mar;98(3):334-8

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

En face enhanced-depth swept-source optical coherence tomography features of chronic central serous chorioretinopathy.

Ferrara D, Mohler KJ, Waheed N, Adhi M, Liu JJ, Grulkowski I, Kraus MF, Baumal C, Hornegger J, Fujimoto JG, Duker JS

Ophthalmology. 2014 Mar;121(3):719-26

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Local control and results of leksell gamma knife therapy for the treatment of uveal melanoma.

Joye RP, Williams LB, Chan MD, Witkin AJ, Schirmer CM, Mignano JE, Wazer DE, Yao KC, Wu JK, Duker JS

Ophthalmic Surg Lasers Imaging Retina. 2014 Mar-Apr;45(2):125-31

Tufts University - Departmental Grant

Keywords: Ocular Oncology, Retina/Retinal Diseases

February, 2014
Intravitreal foscarnet for recurring CMV retinitis in a congenitally infected premature infant.

Tawse KL, Baumal CR

J AAPOS. 2014 Feb;18(1):78-80

Tufts University - Departmental Grant

Keyword: Retina/Retinal Diseases

Pazopanib eye drops: A randomised trial in neovascular age-related macular degeneration.

Danis R, McLaughlin MM, Tolentino M, Staurenghi G, Ye L, Xu CF, Kim RY, Johnson MW, Pazopanib Eye Drops Study Group

Br J Ophthalmol. 2014 Feb;98(2):172-8

Tufts University - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

January, 2014
Analysis of short-term change in subfoveal choroidal thickness in eyes with age-related macular degeneration using optical coherence tomography.

Fein JG, Branchini LA, Manjunath V, Regatieri CV, Fujimoto JG, Duker JS

Ophthalmic Surg Lasers Imaging Retina. 2014 Jan 1;45(1):32-7

Tufts University - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases, Imaging

Electronic address: paulfinger@eyecancer.com, ABS - OOTF Committee.

American Brachytherapy Society - Ophthalmic Oncology Task Force

The american brachytherapy society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma. Brachytherapy. 2014 Jan-Feb;13(1):1-14

Tufts University - Departmental Grant

Keywords: Ocular Oncology, Retina/Retinal Diseases

Late reopening of an initially successfully closed macular hole after 12 years.

Bartolini CE, Goldman DR, Duker JS

Retin Cases Brief Rep. 2014 Winter;8(1):30-2

Tufts University - Departmental Grant

Keyword: Retina/Retinal Diseases

Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration.

Seddon JM, Reynolds R, Yu Y, Rosner B

PLoS One. 2014 Jan 31;9(1):e87047

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy

December, 2013
Analysis of choroidal thickness in eyes treated with focal laser photocoagulation using SD-OCT.

Adhi M, Alwassia AA, Duker JS

Can J Ophthalmol. 2013 Dec;48(6):535-8

Tufts University - Departmental Grant

Keywords: Diabetic Retinopathy, Imaging, Retina/Retinal Diseases

Central serous chorioretinopathy in a 91-year-old woman.

Gobuty M, Adhi M, Duker JS

Br J Ophthalmol. 2013 Dec;97(12):1607,8, 1615-6

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Choriocapillaris and choroidal microvasculature imaging with ultrahigh speed OCT angiography.

Choi W, Mohler KJ, Potsaid B, Lu CD, Liu JJ, Jayaraman V, Cable AE, Duker JS, Huber R, Fujimoto JG

PLoS One. 2013 Dec 11;8(12):e81499

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Genetic and environmental underpinnings to age-related ocular diseases.

Seddon JM

Invest Ophthalmol Vis Sci. 2013 Dec 13;54(14):ORSF28-30

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy

Handheld ultrahigh speed swept source optical coherence tomography instrument using a MEMS scanning mirror.

Lu CD, Kraus MF, Potsaid B, Liu JJ, Choi W, Jayaraman V, Cable AE, Hornegger J, Duker JS, Fujimoto JG

Biomed Opt Express. 2013 Dec 20;5(1):293-311

Tufts University - Departmental Grant

Keyword: Imaging

The international vitreomacular traction study group classification of vitreomacular adhesion, traction, and macular hole.

Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P

Ophthalmology. 2013 Dec;120(12):2611-9

Tufts University - Departmental Grant

Keyword: Retina/Retinal Diseases

November, 2013
Extended duration of transgene expression from pegylated POD nanoparticles enables attenuation of photoreceptor degeneration.

Binder C, Cashman SM, Kumar-Singh R

PLoS One. 2013 Nov 22;8(11):e82295

Tufts University - Departmental Grant

Keywords: Retinitis Pigmentosa, Gene Research/Therapy

Ocriplasmin: A medical or surgical therapy?

Duker JS, Moshfeghi AA

Retina. 2013 Nov-Dec;33(10):2001-2

Tufts University - Departmental Grant

Keyword: Retina/Retinal Diseases

Oct-based interpretation of the vitreomacular interface and indications for pharmacologic vitreolysis.

Stalmans P, Duker JS, Kaiser PK, Heier JS, Dugel PU, Gandorfer A, Sebag J, Haller JA

Retina. 2013 Nov-Dec;33(10):2003-11

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration.

Seddon JM, Yu Y, Miller EC, Reynolds R, Tan PL, Gowrisankar S, Goldstein JI, Triebwasser M, Anderson HE, Zerbib J, Kavanagh D, Souied E, Katsanis N, Daly MJ, Atkinson JP, Raychaudhuri S

Nat Genet. 2013 Nov;45(11):1366-70

Tufts University - Departmental Grant

Keywords: AMD, Epidemiology, Gene Research/Therapy

Reproducibility of a long-range swept-source optical coherence tomography ocular biometry system and comparison with clinical biometers.

Grulkowski I, Liu JJ, Zhang JY, Potsaid B, Jayaraman V, Cable AE, Duker JS, Fujimoto JG

Ophthalmology. 2013 Nov;120(11):2184-90

Tufts University - Departmental Grant

Keyword: Imaging

Surgical outcomes after application of a liquid adhesive ocular bandage to clear corneal incisions during cataract surgery.

Uy HS, Kenyon KR

J Cataract Refract Surg. 2013 Nov;39(11):1668-74

Tufts University - Departmental Grant

Keyword: Cornea

October, 2013
Adeno-associated virus mediated delivery of a non-membrane targeted human soluble CD59 attenuates some aspects of diabetic retinopathy in mice.

Adhi M, Cashman SM, Kumar-Singh R

PLoS One. 2013 Oct 22;8(10):e79661

Tufts University - Departmental Grant

Keywords: Diabetic Retinopathy, Gene Research/Therapy, Nanotechnology/Drug Delivery, Retina/Retinal Diseases

Analysis of morphological features and vascular layers of choroid in diabetic retinopathy using spectral-domain optical coherence tomography.

Adhi M, Brewer E, Waheed NK, Duker JS

JAMA Ophthalmol. 2013 Oct;131(10):1267-74

Tufts University - Departmental Grant

Keywords: Diabetic Retinopathy, Imaging

Aurintricarboxylic acid inhibits complement activation, membrane attack complex, and choroidal neovascularization in a model of macular degeneration.

Lipo E, Cashman SM, Kumar-Singh R

Invest Ophthalmol Vis Sci. 2013 Oct 29;54(10):7107-14

Tufts University - Departmental Grant

Keywords: AMD, Nanotechnology/Drug Delivery, Retina/Retinal Diseases

Diameters of retinal blood vessels in a healthy cohort as measured by spectral domain optical coherence tomography.

Goldenberg D, Shahar J, Loewenstein A, Goldstein M

Retina. 2013 Oct;33(9):1888-94

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Topical application of PPADS inhibits complement activation and choroidal neovascularization in a model of age-related macular degeneration.

Birke K, Lipo E, Birke MT, Kumar-Singh R

PLoS One. 2013 Oct 9;8(10):e76766

Tufts University - Departmental Grant

Keywords: AMD, Nanotechnology/Drug Delivery, Retina/Retinal Diseases

September, 2013
Analysis of choroidal morphologic features and vasculature in healthy eyes using spectral-domain optical coherence tomography.

Branchini LA, Adhi M, Regatieri CV, Nandakumar N, Liu JJ, Laver N, Fujimoto JG, Duker JS

Ophthalmology. 2013 Sep;120(9):1901-8

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Spontaneous improvement of macular traction retinal detachment associated with myopic macular schisis.

Goldman DR, Duker JS

Ophthalmic Surg Lasers Imaging Retina. 2013 Sep-Oct;44(5):497-8

Tufts University - Departmental Grant

Keywords: Myopia/Presbyopia, Retinal Detachment

August, 2013
American glaucoma society position statement: Glaucoma surgery by surgeons.

Mattox C, Tsai JC, Patient Care Committee of the American Glaucoma Society

J Glaucoma. 2013 Aug;22(6):515

Tufts University - Departmental Grant

Keyword: Glaucoma

Bilateral toxoplasmosis retinitis associated with ruxolitinib.

Goldberg RA, Reichel E, Oshry LJ

N Engl J Med. 2013 Aug 15;369(7):681-3

Tufts University - Departmental Grant

Keywords: Uveitis/Infectious Diseases, Retina/Retinal Diseases

Modulation of ocular surface glycocalyx barrier function by a galectin-3 N-terminal deletion mutant and membrane-anchored synthetic glycopolymers.

Mauris J, Mantelli F, Woodward AM, Cao Z, Bertozzi CR, Panjwani N, Godula K, Argueso P

PLoS One. 2013 Aug 19;8(8):e72304

Tufts University - Departmental Grant

Keywords: Cornea, Dry Eye

The relationship between retinal and choroidal thickness and visual acuity in highly myopic eyes.

Flores-Moreno I, Ruiz-Medrano J, Duker JS, Ruiz-Moreno JM

Br J Ophthalmol. 2013 Aug;97(8):1010-3

Tufts University - Departmental Grant

Keyword: Myopia/Presbyopia

July, 2013
Diagnostic and therapeutic challenges.

Liang MC, Vora RA, Duker JS, Spaide RF

Retina. 2013 Jul-Aug;33(7):1471-4

Tufts University - Departmental Grant

Keyword: Retina/Retinal Diseases

June, 2013
Diagnostic and therapeutic challenges.

Chen JJ, Vora RA, Arrigg P, Duker JS, Keane PA, Sadda SR, Yang SS

Retina. 2013 Jun;33(6):1273-8

Tufts University - Departmental Grant

Keywords: Glaucoma, Retina/Retinal Diseases

Dramatic regression of persistent tunica vasculosa lentis associated with retinopathy of prematurity following treatment with intravitreal bevacizumab.

Goldman DR, Baumal CR

J Pediatr Ophthalmol Strabismus. 2013 Jun 4;50 Online:e27-9

Tufts University - Departmental Grant

Keyword: Retina/Retinal Diseases

Galectin-1-mediated suppression of pseudomonas aeruginosa-induced corneal immunopathology.

Suryawanshi A, Cao Z, Thitiprasert T, Zaidi TS, Panjwani N

J Immunol. 2013 Jun 15;190(12):6397-409

Tufts University - Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

May, 2013
Analysis of the morphology and vascular layers of the choroid in retinitis pigmentosa using spectral-domain OCT.

Adhi M, Regatieri CV, Branchini LA, Zhang JY, Alwassia AA, Duker JS

Ophthalmic Surg Lasers Imaging Retina. 2013 May-Jun;44(3):252-9

Tufts University - Departmental Grant

Keywords: Imaging, Retinitis Pigmentosa

Dietary omega-3 fatty acids, other fat intake, genetic susceptibility, and progression to incident geographic atrophy.

Reynolds R, Rosner B, Seddon JM

Ophthalmology. 2013 May;120(5):1020-8

Tufts University - Departmental Grant

Keywords: AMD, Epidemiology

Effect of intravitreous anti-vascular endothelial growth factor therapy on choroidal thickness in neovascular age-related macular degeneration using spectral-domain optical coherence tomography.

Branchini L, Regatieri C, Adhi M, Flores-Moreno I, Manjunath V, Fujimoto JG, Duker JS

JAMA Ophthalmol. 2013 May;131(5):693-4

Tufts University - Departmental Grant

Keywords: AMD, Imaging

Optical coherence tomography--current and future applications.

Adhi M, Duker JS

Curr Opin Ophthalmol. 2013 May;24(3):213-21

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

April, 2013
Angiosarcoma presenting with minor erythema and swelling.

Cox CA, Wein RO, Ghafouri R, Laver NM, Heher KL, Kapadia MK

Case Rep Ophthalmol. 2013 Apr 5;4(1):59-63

Tufts University - Departmental Grant

Keyword: Ocular Oncology/Pterygium

Mutation-independent rescue of a novel mouse model of retinitis pigmentosa.

Greenwald DL, Cashman SM, Kumar-Singh R

Gene Ther. 2013 Apr;20(4):425-34

Tufts University - Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

Validation of a prediction algorithm for progression to advanced macular degeneration subtypes.

Seddon JM, Reynolds R, Yu Y, Rosner B

JAMA Ophthalmol. 2013 Apr;131(4):448-55

Tufts University - Departmental Grant

Keywords: AMD, Epidemiology

March, 2013
Managing a case of V pattern esotropia.

Strominger MB, Young WO

J Pediatr Ophthalmol Strabismus. 2013 Mar-Apr;50(2):70-2

Tufts University - Departmental Grant

Keyword: Pediatric

Reactive retinal astrocytic tumors (so-called vasoproliferative tumors): Histopathologic, immunohistochemical, and genetic studies of four cases.

Poole Perry LJ, Jakobiec FA, Zakka FR, Reichel E, Herwig MC, Perry A, Brat DJ, Grossniklaus HE

Am J Ophthalmol. 2013 Mar;155(3):593-608.e1

Tufts University - Departmental Grant

Keywords: Ocular Oncology/Pterygium, Retina/Retinal Diseases

Retinal neovascularization secondary to proliferative diabetic retinopathy characterized by spectral domain optical coherence tomography.

Cho H, Alwassia AA, Regiatieri CV, Zhang JY, Baumal C, Waheed N, Duker JS

Retina. 2013 Mar;33(3):542-7

Tufts University - Departmental Grant

Keywords: Diabetic Retinopathy, Imaging

February, 2013
American glaucoma society position statement: Electronic data standards for clinical practice.

Boland MV, Schuman JS, Mattox CG, Patient Care Committee of the American Glaucoma Society

J Glaucoma. 2013 Feb;22(2):174-5

Tufts University - Departmental Grant

Keyword: Glaucoma

Bilateral simultaneous central serous chorioretinopathy in a teenage girl with systemic arterial hypertension.

Alwassia AA, Adhi M, Duker JS

Int Ophthalmol. 2013 Feb;33(1):79-82

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Epimacular brachytherapy for neovascular age-related macular degeneration: A randomized, controlled trial (CABERNET).

Dugel PU, Bebchuk JD, Nau J, Reichel E, Singer M, Barak A, Binder S, Jackson TL, CABERNET Study Group

Ophthalmology. 2013 Feb;120(2):317-27

Tufts University - Departmental Grant

Keywords: AMD, Other: Therapy

In vivo imaging of the rodent eye with swept source/Fourier domain OCT.

Liu JJ, Grulkowski I, Kraus MF, Potsaid B, Lu CD, Baumann B, Duker JS, Hornegger J, Fujimoto JG

Biomed Opt Express. 2013 Feb 1;4(2):351-63

Tufts University - Departmental Grant

Keyword: Imaging

Optical coherence tomography-guided facedown positioning for macular hole surgery.

Shah SP, Manjunath V, Rogers AH, Baumal CR, Reichel E, Duker JS

Retina. 2013 Feb;33(2):356-62

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Phase-sensitive swept-source optical coherence tomography imaging of the human retina with a vertical cavity surface-emitting laser light source.

Choi W, Potsaid B, Jayaraman V, Baumann B, Grulkowski I, Liu JJ, Lu CD, Cable AE, Huang D, Duker JS, Fujimoto JG

Opt Lett. 2013 Feb 1;38(3):338-40

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

The relationship between axial length and choroidal thickness in eyes with high myopia.

Flores-Moreno I, Lugo F, Duker JS, Ruiz-Moreno JM

Am J Ophthalmol. 2013 Feb;155(2):314-9.e1

Tufts University - Departmental Grant

Keywords: Imaging, Myopia/Presbyopia

January, 2013
De novo appearance of a choroidal osteoma in an eye with previous branch retinal vein occlusion.

Adhi M, Bryant JS, Alwassia AA, Chen C, Duker JS

Ophthalmic Surg Lasers Imaging Retina. 2013 Jan-Feb;44(1):77-80

Tufts University - Departmental Grant

Keyword: Retinal Vein and Artery Occlusion

Exercise-induced acute changes in systolic blood pressure do not alter choroidal thickness as measured by a portable spectral-domain optical coherence tomography device.

Alwassia AA, Adhi M, Zhang JY, Regatieri CV, Al-Quthami A, Salem D, Fujimoto JG, Duker JS

Retina. 2013 Jan;33(1):160-5

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

December, 2012
CCN5 expression in mammals.

Myers RB, Rwayitare K, Richey L, Lem J, Castellot JJ,Jr

III. early embryonic mouse development. J Cell Commun Signal. 2012 Dec;6(4):217-23

Tufts University - Departmental Grant

Keyword: Other: Embryo Expression Pattern

November, 2012
Correction of phenotype misclassification based on high-discrimination genetic predictive risk models.

Ioannidis JP, Yu Y, Seddon JM

Epidemiology. 2012 Nov;23(6):902-9

Tufts University - Departmental Grant

Keywords: Epidemiology, Gene Research/Therapy

Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers.

Grulkowski I, Liu JJ, Potsaid B, Jayaraman V, Lu CD, Jiang J, Cable AE, Duker JS, Fujimoto JG

Biomed Opt Express. 2012 Nov 1;3(11):2733-51

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

To correct or not to correct-and how.

Ioannidis JP, Yu Y, Seddon JM

Epidemiology. 2012 Nov;23(6):912-3

Tufts University - Departmental Grant

Keywords: Epidemiology, Gene Research/Therapy

October, 2012
A multicenter analysis of the ophthalmic knowledge assessment program and american board of ophthalmology written qualifying examination performance.

Lee AG, Oetting TA, Blomquist PH, Bradford G, Culican SM, Kloek C, Krishnan C, Lauer AK, Levi L, Naseri A, Rubin SE, Scott IU, Tao J, Tuli S, Wright MM, Wudunn D, Zimmerman MB

Ophthalmology. 2012 Oct;119(10):1949-53

Tufts University - Departmental Grant

Keyword: Other: Ophthalmic Knowledge Assessment

Cancer of unknown primary: From immunohistochemistry to gene expression profiling.

Chiang WM, Kapadia M, Laver NV, Nystrom JS

J Clin Oncol. 2012 Oct 10;30(29):e300-2

Tufts University - Departmental Grant

Keywords: Gene Research/Therapy, Ocular Oncology/Pterygium

Myopic schisis with scrolled posterior hyaloid.

Reisner AA, Vora RA, Goldman DR, Duker JS

Arch Ophthalmol. 2012 Oct 1;130(10):1357

Tufts University - Departmental Grant

Keywords: Imaging, Myopia/Presbyopia, Retina/Retinal Diseases

Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edema.

Campochiaro PA, Brown DM, Pearson A, Chen S, Boyer D, Ruiz-Moreno J, Garretson B, Gupta A, Hariprasad SM, Bailey C, Reichel E, Soubrane G, Kapik B, Billman K, Kane FE, Green K, FAME Study Group

Ophthalmology. 2012 Oct;119(10):2125-32

Tufts University - Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

Use of optical coherence tomography in the diagnosis and management of uveitis.

Regatieri CV, Alwassia A, Zhang JY, Vora R, Duker JS

Int Ophthalmol Clin. 2012 Fall;52(4):33-43

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases, Uveitis/Infectious Diseases

September, 2012
Bilateral simultaneous stage 1 macular hole.

Alwassia AA, Adhi M, Duker JS

Ophthalmic Surg Lasers Imaging. 2012 Sep 27;43 Online:e99-e103

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.

Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH, Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA, Lee AY, Leveziel N, Zack DJ, Campochiaro P, Smith RT, Barile GR, Hogg RE, Chakravarthy U, Behrens TW, Uitterlinden AG, van Duijn CM, Vingerling JR, Brantley MA,Jr, Baird PN, Klaver CC, Allikmets R, Katsanis N, Graham RR, Ioannidis JP, Daly MJ, Seddon JM

Ophthalmology. 2012 Sep;119(9):1874-85

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Retina/Retinal Diseases

The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: A HuGE review and meta-analysis.

Thakkinstian A, McEvoy M, Chakravarthy U, Chakrabarti S, McKay GJ, Ryu E, Silvestri G, Kaur I, Francis P, Iwata T, Akahori M, Arning A, Edwards AO, Seddon JM, Attia J

Am J Epidemiol. 2012 Sep 1;176(5):361-72

Tufts University - Departmental Grant

Keywords: AMD, Epidemiology, Gene Research/Therapy, Retina/Retinal Diseases

July, 2012
Genetic factors for choroidal neovascularization associated with high myopia.

Leveziel N, Yu Y, Reynolds R, Tai A, Meng W, Caillaux V, Calvas P, Rosner B, Malecaze F, Souied EH, Seddon JM

Invest Ophthalmol Vis Sci. 2012 Jul 27;53(8):5004-9

Tufts University - Departmental Grant

Keywords: Gene Research/Therapy, Myopia/Presbyopia, Retina/Retinal Diseases

May, 2012
Age-related macular degeneration.

Lim LS, Mitchell P, Seddon JM, Holz FG, Wong TY

Lancet. 2012 May 5;379(9827):1728-38

Tufts University - Departmental Grant

Keywords: AMD, Epidemiology, Gene Research/Therapy, Retina/Retinal Diseases

Choroidal imaging using spectral-domain optical coherence tomography.

Regatieri CV, Branchini L, Fujimoto JG, Duker JS

Retina. 2012 May;32(5):865-76

Tufts University - Departmental Grant

Keywords: AMD, Diabetic Retinopathy, Imaging, Retina/Retinal Diseases

Measurement of pulsatile total blood flow in the human and rat retina with ultrahigh speed spectral/Fourier domain OCT.

Choi W, Baumann B, Liu JJ, Clermont AC, Feener EP, Duker JS, Fujimoto JG

Biomed Opt Express. 2012 May 1;3(5):1047-61

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

April, 2012
Swept source/Fourier domain polarization sensitive optical coherence tomography with a passive polarization delay unit.

Baumann B, Choi W, Potsaid B, Huang D, Duker JS, Fujimoto JG

Opt Express. 2012 Apr 23;20(9):10218-30

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

March, 2012
Choroidal thickness in patients with diabetic retinopathy analyzed by spectral-domain optical coherence tomography.

Regatieri CV, Branchini L, Carmody J, Fujimoto JG, Duker JS

Retina. 2012 Mar;32(3):563-8

Tufts University - Departmental Grant

Keywords: Diabetic Retinopathy, Imaging, Other: Choroidal Angiopathy

Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate markov models.

Yu Y, Reynolds R, Rosner B, Daly MJ, Seddon JM

Invest Ophthalmol Vis Sci. 2012 Mar 21;53(3):1548-56

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Retina/Retinal Diseases

February, 2012
BEDVH-A method for evaluating biologically effective dose volume histograms: Application to eye plaque brachytherapy implants.

Gagne NL, Leonard KL, Huber KE, Mignano JE, Duker JS, Laver NV, Rivard MJ

Med Phys. 2012 Feb;39(2):976-83

Tufts University - Departmental Grant

Keywords: Ocular Oncology/Pterygium, Retina/Retinal Diseases, Other: Brachytherapy

Increased risk of secondary uterine leiomyosarcoma in hereditary retinoblastoma.

Francis JH, Kleinerman RA, Seddon JM, Abramson DH

Gynecol Oncol. 2012 Feb;124(2):254-9

Tufts University - Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Retinoblastoma

January, 2012
Galectin-8 promotes cytoskeletal rearrangement in trabecular meshwork cells through activation of rho signaling.

Diskin S, Chen WS, Cao Z, Gyawali S, Gong H, Soza A, Gonzalez A, Panjwani N

PLoS One. 2012;7(9):e44400

Tufts University - Departmental Grant

Keyword: Glaucoma

Reproducibility of choroidal thickness measurements across three spectral domain optical coherence tomography systems.

Branchini L, Regatieri CV, Flores-Moreno I, Baumann B, Fujimoto JG, Duker JS

Ophthalmology. 2012 Jan;119(1):119-23

Tufts University - Departmental Grant

Keywords: Imaging, Other: Choroidal Thickness, Other: Spectral Doman Optical Coherence Tomography

Retinal nerve fibre layer and visual function loss in glaucoma: The tipping point.

Wollstein G, Kagemann L, Bilonick RA, Ishikawa H, Folio LS, Gabriele ML, Ungar AK, Duker JS, Fujimoto JG, Schuman JS

Br J Ophthalmol. 2012 Jan;96(1):47-52

Tufts University - Departmental Grant

Keywords: Glaucoma, Imaging, Retina/Retinal Diseases

Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics.

Makino CL, Wen XH, Michaud NA, Covington HI, DiBenedetto E, Hamm HE, Lem J, Caruso G

PLoS One. 2012;7(5):e37832

Tufts University - Departmental Grant

Keyword: Retina/Retinal Diseases

December, 2011
Evaluation of new and established age-related macular degeneration susceptibility genes in the women's health initiative sight exam (WHI-SE) study.

Peter I, Huggins GS, Ordovas JM, Haan M, Seddon JM

Am J Ophthalmol. 2011 Dec;152(6):1005,1013.e1

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Genetics, Retina/Retinal Diseases

November, 2011
Automated discovery and quantification of image-based complex phenotypes: A twin study of drusen phenotypes in age-related macular degeneration.

Quellec G, Russell SR, Seddon JM, Reynolds R, Scheetz T, Mahajan VB, Stone EM, Abramoff MD

Invest Ophthalmol Vis Sci. 2011 Nov 25;52(12):9195-206

Tufts University - Departmental Grant

Keywords: AMD, Imaging, Retina/Retinal Diseases

Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors.

Seddon JM, Reynolds R, Yu Y, Daly MJ, Rosner B

Ophthalmology. 2011 Nov;118(11):2203-11

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Genetics, Retina/Retinal Diseases

October, 2011
Analysis of choroidal thickness in age-related macular degeneration using spectral-domain optical coherence tomography.

Manjunath V, Goren J, Fujimoto JG, Duker JS

Am J Ophthalmol. 2011 Oct;152(4):663-8

Tufts University - Departmental Grant

Keywords: AMD, Imaging, Retina/Retinal Diseases

Analysis of normal peripapillary choroidal thickness via spectral domain optical coherence tomography.

Ho J, Branchini L, Regatieri C, Krishnan C, Fujimoto JG, Duker JS

Ophthalmology. 2011 Oct;118(10):2001-7

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.

Raychaudhuri S, Iartchouk O, Chin K, Tan PL, Tai AK, Ripke S, Gowrisankar S, Vemuri S, Montgomery K, Yu Y, Reynolds R, Zack DJ, Campochiaro B, Campochiaro P, Katsanis N, Daly MJ, Seddon JM

Nat Genet. 2011 Oct 23;43(12):1232-6

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Genetics, Retina/Retinal Diseases

Computerized macular pathology diagnosis in spectral domain optical coherence tomography scans based on multiscale texture and shape features.

Liu YY, Ishikawa H, Chen M, Wollstein G, Duker JS, Fujimoto JG, Schuman JS, Rehg JM

Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8316-22

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

September, 2011
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.

Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH, Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA, Sobrin L, Evangelou E, Lee PH, Lee AY, Leveziel N, Zack DJ, Campochiaro B, Campochiaro P, Smith RT, Barile GR, Guymer RH, Hogg R, Chakravarthy U, Robman LD, Gustafsson O, Sigurdsson H, Ortmann W, Behrens TW, Stefansson K, Uitterlinden AG, van Duijn CM, Vingerling JR, Klaver CC, Allikmets R, Brantley MA,Jr, Baird PN, Katsanis N, Thorsteinsdottir U, Ioannidis JP, Daly MJ, Graham RR, Seddon JM

Hum Mol Genet. 2011 Sep 15;20(18):3699-709

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Genetics, Retina/Retinal Diseases

August, 2011
Galectin-3 protein modulates cell surface expression and activation of vascular endothelial growth factor receptor 2 in human endothelial cells.

Markowska AI, Jefferies KC, Panjwani N

J Biol Chem. 2011 Aug 26;286(34):29913-21

Tufts University - Departmental Grant

Keywords: AMD, Cornea Transplants, Diabetic Retinopathy

July, 2011
Smoking, dietary betaine, methionine, and vitamin D in monozygotic twins with discordant macular degeneration: Epigenetic implications.

Seddon JM, Reynolds R, Shah HR, Rosner B

Ophthalmology. 2011 Jul;118(7):1386-94

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Genetics, Retina/Retinal Diseases

June, 2011
Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.

Yu Y, Reynolds R, Fagerness J, Rosner B, Daly MJ, Seddon JM

Invest Ophthalmol Vis Sci. 2011 Jun 28;52(7):4663-70

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Genetics, Retina/Retinal Diseases

May, 2011
Expression of complement component 3 (C3) from an adenovirus leads to pathology in the murine retina.

Cashman SM, Desai A, Ramo K, Kumar-Singh R

Invest Ophthalmol Vis Sci. 2011 May 18;52(6):3436-45

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Retina/Retinal Diseases

April, 2011
A non membrane-targeted human soluble CD59 attenuates choroidal neovascularization in a model of age related macular degeneration.

Cashman SM, Ramo K, Kumar-Singh R

PLoS One. 2011 Apr 28;6(4):e19078

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Retina/Retinal Diseases

Documentation of intraretinal retinal pigment epithelium migration via high-speed ultrahigh-resolution optical coherence tomography.

Ho J, Witkin AJ, Liu J, Chen Y, Fujimoto JG, Schuman JS, Duker JS

Ophthalmology. 2011 Apr;118(4):687-93

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

March, 2011
Analysis of peripapillary atrophy using spectral domain optical coherence tomography.

Manjunath V, Shah H, Fujimoto JG, Duker JS

Ophthalmology. 2011 Mar;118(3):531-6

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

Nuclear targeted delivery of macromolecules to retina and cornea.

Binder C, Read SP, Cashman SM, Kumar-Singh R

J Gene Med. 2011 Mar;13(3):158-70

Tufts University - Departmental Grant

Keywords: Cornea, Gene Research/Therapy, Retina/Retinal Diseases

Posterior lattice degeneration characterized by spectral domain optical coherence tomography.

Manjunath V, Taha M, Fujimoto JG, Duker JS

Retina. 2011 Mar;31(3):492-6

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

February, 2011
ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration.

Sobrin L, Reynolds R, Yu Y, Fagerness J, Leveziel N, Bernstein PS, Souied EH, Daly MJ, Seddon JM

Am J Ophthalmol. 2011 Feb;151(2):345,52.e3

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Genetics, Retina/Retinal Diseases

January, 2011
Focus on molecules: Galectin-3.

Argueso P, Panjwani N

Exp Eye Res. 2011 Jan;92(1):2-3

Tufts University - Departmental Grant

Keywords: Cornea, Dry Eye

Soluble CD59 expressed from an adenovirus in vivo is a potent inhibitor of complement deposition on murine liver vascular endothelium.

Gandhi J, Cashman SM, Kumar-Singh R

PLoS One. 2011;6(6):e21621

Tufts University - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Retina/Retinal Diseases

Ultra-high-resolution optical coherence tomographic findings in commotio retinae.

Bradley JL, Shah SP, Manjunath V, Fujimoto JG, Duker JS, Reichel E

Arch Ophthalmol. 2011 Jan;129(1):107-8

Tufts University - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

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