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Research to Prevent Blindness

Research Database

Medical University of South Carolina Research, funded by RPB in 2013 & 2014 matching Departmental Grant

43 Citations, Sorted by Month and Year

November, 2014
Photoscreeners in the pediatric eye office: Compared testability and refractions on high risk children.

Peterseim MM, Papa CE, Wilson ME, Cheeseman EW, Wolf BJ, Davidson JD, Trivedi RH

Am J Ophthalmol. 2014 Nov;158(5):932-8

Medical University of South Carolina - Departmental Grant

Keywords: Myopia/Presbyopia, Pediatric

October, 2014
Acetylation: A lysine modification with neuroprotective effects in ischemic retinal degeneration.

Alsarraf O, Fan J, Dahrouj M, Chou CJ, Menick DR, Crosson CE

Exp Eye Res. 2014 Oct;127:124-31

Medical University of South Carolina - Departmental Grant

Keywords: Glaucoma, Retina/Retinal Diseases

A comparative analysis of C57BL/6J and 6N substrains: Chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization.

Schnabolk G, Stauffer K, O’Quinn E, Coughlin B, Kunchithapautham K, Rohrer B

Exp Eye Res. 2014 Oct;129:18-23

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Gene Research/Therapy

Brittle cornea syndrome: A case report and comparison with Ehlers Danlos syndrome.

Ramappa M, Wilson ME, Rogers RC, Trivedi RH

J AAPOS. 2014 Oct;18(5):509-11

Medical University of South Carolina - Departmental Grant

Keywords: Cornea, Myopia/Presbyopia

Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X.

Tam BM, Noorwez SM, Kaushal S, Kono M, Moritz OL

laevis transgenic models of retinitis pigmentosa. J Neurosci. 2014 Oct 1;34(40):13336-48

Medical University of South Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

Regulation of nitric oxide production by δ-opioid receptors during glaucomatous injury.

Husain S, Abdul Y, Singh S, Ahmad A, Husain M

PLoS One. 2014 Oct 17;9(10):e110397

Medical University of South Carolina - Departmental Grant

Keywords: Glaucoma, Optic Neuropathy

September, 2014
Molecular imaging reveals elevated VEGFR-2 expression in retinal capillaries in diabetes: a novel biomarker for early diagnosis.

Sun D, Nakao S, Xie F, Zandi S, Bagheri A, Rezaei Kanavi M, Samiei S, Soheili ZS, Frimmel S, Zhang Z, Ablonczy Z, Ahmadieh H, Hafezi-Moghadam A

FASEB J. 2014 Sep;28:3942-51

Medical University of South Carolina - Departmental Grant

Keywords: Diabetic Retinopathy, Imaging

July, 2014
Coexpression of three opsins in cone photoreceptors of the salamander Ambystoma tigrinum.

Isayama T, Chen Y, Kono M, Fabre E, Stavsky M, Degrip WJ, Ma JX, Crouch RK, Makino CL

J Comp Neurol. 2014 Jul 1;522(10):2249-65

Medical University of South Carolina - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

HIV and cannot see.

Prospero Ponce CM, Al Zubidi N, Beaver HA, Lee AG, Huey DA, Chavis PS

Surv Ophthalmol. 2014 Jul-Aug;59(4):468-73

Medical University of South Carolina - Departmental Grant

Keywords: Uveitis/Infectious Diseases, Other: Panophthalmitis

Quantitative autofluorescence and cell density maps of the human retinal pigment epithelium.

Ach T, Huisingh C, McGwin G Jr, Messinger JD, Zhang T, Bentley MJ, Gutierrez DB, Ablonczy Z, Smith RT, Sloan KR, Curcio CA

Invest Ophthalmol Vis Sci. 2014 Jul 17;55(8):4832-41

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Imaging

June, 2014
Comparison of contact lens and intraocular lens correction of monocular aphakia during infancy: A randomized clinical trial of HOTV Optotype acuity at age 4.5 years and clinical findings at age 5 years.

The Infant Aphakia Treatment Study Group, Lambert SR, Lynn MJ, Hartmann EE, Dubois L, Drews-Botsch C, Freedman SF, Plager DA, Buckley EG, Wilson ME

JAMA Ophthalmol. 2014 Jun;132(6):676-82

Medical University of South Carolina - Departmental Grant

Keywords: Cataract, Cornea

The role of preoperative biometry in selecting initial contact lens power in the infant Aphakia Treatment Study.

Trivedi RH, Lambert SR, Lynn MJ, Wilson ME, Infant Aphakia Treatment Study Group

J AAPOS. 2014 Jun;18(3):251-4

Medical University of South Carolina - Departmental Grant

Keywords: Cataract, Pediatric

May, 2014
Progressive dysfunction of the retinal pigment epithelium and retina due to increased VEGF-A levels.

Ablonczy Z, Dahrouj M, Maneros AG

FASEB J. 2014 May;28(5):2369-79

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Other: Choroidal Neovascularization

Smoke-exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation.

Kunchithapautham K, Atkinson C, Rohrer B

J Biol Chem. 2014 May 23;289(21):14534-46

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

April, 2014
The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometry.

Ablonczy Z, Smith N, Anderson DM, Grey AC, Spraggins J, Koutalos Y, Schey KL, Crouch RK

Proteomics. 2014 Apr;14(7-8):936-44

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Imaging

Vascular endothelial growth factor modulates the function of the retinal pigment epithelium in vivo.

Dahrouj M, Alsarraf O, McMillin JC, Liu Y, Crosson CE, Ablonczy Z

Invest Ophthalmol Vis Sci. 2014 Apr 9;55(4):2269-75

Medical University of South Carolina - Departmental Grant

Keywords: Diabetic Retinopathy, Other: Retinal Edema

March, 2014
Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β-protein.

Barnwell E, Padmaraju V, Baranello R, Pacheco-Quinto J, Crosson C, Ablonczy Z, Eckman E, Eckman CB, Ramakrishnan V, Greig NH, Pappolla MA, Sambarmurti K

PLoS One. 2014 Mar 21;9(3):e91531

Medical University of South Carolina - Departmental Grant

Keywords: Epidemiology, Nanotechnology/Drug Delivery

February, 2014
Interferon-gamma (IFN-γ)-mediated retinal ganglion cell death in human tyrosinase T cell receptor transgenic mouse.

Husain S, Abdul Y, Webster C, Chatterjee S, Kesarwani P, Mehrotra S

PLoS One. 2014 Feb 28;9(2):e89392

Medical University of South Carolina - Departmental Grant

Keywords: Gene Research/Therapy, Optic Neuropathy

January, 2014
Mitochondria contribute to NADPH generation in mouse rod photoreceptors.

Adler L 4th, Chen C, Koutalos Y

J Biol Chem. 2014 Jan 17;289(3):1519-28

Medical University of South Carolina - Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

December, 2013
Predictability of intraocular lens power calculation formulae in infantile eyes with unilateral congenital cataract: Results from the infant aphakia treatment study.

Vanderveen DK, Trivedi RH, Nizam A, Lynn MJ, Lambert SR, Infant Aphakia Treatment Study Group

Am J Ophthalmol. 2013 Dec;156(6):1252-60.e2

Medical University of South Carolina - Departmental Grant

Keywords: Cataract, Pediatric

November, 2013
Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium.

Ablonczy Z, Higbee D, Grey AC, Koutalos Y, Schey KL, Crouch RK

Arch Biochem Biophys. 2013 Nov 15;539(2):196-202

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Macular Dystrophy

October, 2013
Clinical results of using a high-repetition-rate excimer laser with an optimized ablation profile for myopic correction in 10 235 eyes.

Tomita M, Waring GO,4th, Magnago T, Watabe M

J Cataract Refract Surg. 2013 Oct;39(10):1543-9

Medical University of South Carolina - Departmental Grant

Keywords: Cornea, Myopia/Presbyopia

Delta-opioid receptors attenuate TNF-alpha-induced MMP-2 secretion from human ONH astrocytes.

Akhter N, Nix M, Abdul Y, Singh S, Husain S

Invest Ophthalmol Vis Sci. 2013 Oct 9;54(10):6605-11

Medical University of South Carolina - Departmental Grant

Keywords: Glaucoma, Optic Neuropathy

Pigment epithelium-derived factor decreases outflow facility.

Rogers ME, Navarro ID, Perkumas KM, Niere SM, Allingham RR, Crosson CE, Stamer WD

Invest Ophthalmol Vis Sci. 2013 Oct 11;54(10):6655-61

Medical University of South Carolina - Departmental Grant

Keyword: Glaucoma

Selection of an initial contact lens power for infantile cataract surgery without primary intraocular lens implantation.

Trivedi RH, Wilson ME

Ophthalmology. 2013 Oct;120(10):1973-6

Medical University of South Carolina - Departmental Grant

Keywords: Cataract, Pediatric

August, 2013
Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium.

Ablonczy Z, Higbee D, Anderson DM, Dahrouj M, Grey AC, Gutierrez D, Koutalos Y, Schey KL, Hanneken A, Crouch RK

Invest Ophthalmol Vis Sci. 2013 Aug 15;54(8):5535-42

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Macular Dystrophy

July, 2013
A rapidly expanding orbital lesion.

Magrath GN, Cheeseman EW, Eiseman AS, Caplan MJ

J Pediatr. 2013 Jul;163(1):294-5.e1-2

Medical University of South Carolina - Departmental Grant

Keywords: Pediatric, Other: Orbital Lesion

Noncanonical autophagy promotes the visual cycle.

Kim JY, Zhao H, Martinez J, Doggett TA, Kolesnikov AV, Tang PH, Ablonczy Z, Chan CC, Zhou Z, Green DR, Ferguson TA

Cell. 2013 Jul 18;154(2):365-76

Medical University of South Carolina - Departmental Grant

Keywords: Macular Dystrophy, Retina/Retinal Diseases

June, 2013
Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury.

Woodell A, Coughlin B, Kunchithapautham K, Casey S, Williamson T, Ferrell WD, Atkinson C, Jones BW, Rohrer B

PLoS One. 2013 Jun 25;8(6):e67894

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Other: Inflammation

Inhibition of HDAC2 protects the retina from ischemic injury.

Fan J, Alsarraf O, Dahrouj M, Platt KA, Chou CJ, Rice DS, Crosson CE

Invest Ophthalmol Vis Sci. 2013 Jun 12;54(6):4072-80

Medical University of South Carolina - Departmental Grant

Keywords: Optic Neuropathy, Glaucoma

May, 2013
Detection of complement activation using monoclonal antibodies against C3d.

Thurman JM, Kulik L, Orth H, Wong M, Renner B, Sargsyan SA, Mitchell LM, Hourcade DE, Hannan JP, Kovacs JM, Coughlin B, Woodell AS, Pickering MC, Rohrer B, Holers VM

J Clin Invest. 2013 May 1;123(5):2218-30

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Imaging

Explant cultures of Rpe65-/- mouse retina: A model to investigate cone opsin trafficking.

Bandyopadhyay M, Kono M, Rohrer B

Mol Vis. 2013 May 29;19:1149-57

Medical University of South Carolina - Departmental Grant

Keyword: Other: Leber Congenital Amaurosis Type 2

Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.

Joseph K, Kulik L, Coughlin B, Kunchithapautham K, Bandyopadhyay M, Thiel S, Thielens NM, Holers VM, Rohrer B

J Biol Chem. 2013 May 3;288(18):12753-65

Medical University of South Carolina - Departmental Grant

Keywords: AMD, Other: Inflammation

April, 2013
Essential roles of grp94 in gut homeostasis via chaperoning canonical wnt pathway.

Liu B, Staron M, Hong F, Wu BX, Sun S, Morales C, Crosson CE, Tomlinson S, Kim I, Wu D, Li Z

Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6877-82

Medical University of South Carolina - Departmental Grant

Keywords: Other: Cancer, Other: Ocular Development

March, 2013
A weed by any other name.

Burger BM, Chavis PS, Purvin V

Surv Ophthalmol. 2013 Mar-Apr;58(2):176-83

Medical University of South Carolina - Departmental Grant

Keyword: Neuro-Ophthalmology

Delta-opioid agonist SNC-121 protects retinal ganglion cell function in a chronic ocular hypertensive rat model.

Abdul Y, Akhter N, Husain S

Invest Ophthalmol Vis Sci. 2013 Mar 11;54(3):1816-28

Medical University of South Carolina - Departmental Grant

Keywords: Glaucoma, Optic Neuropathy

Horner syndrome.

Proctor C, Chavis PS

J Neuroophthalmol. 2013 Mar;33(1):88-9

Medical University of South Carolina - Departmental Grant

Keyword: Neuro-Ophthalmology

Orbital cellulitis complicated by central retinal artery occlusion.

Proctor CM, Magrath GN, de Castro LE, Johnson JH, Teed RG

Ophthal Plast Reconstr Surg. 2013 Mar-Apr;29(2):e59-61

Medical University of South Carolina - Departmental Grant

Keywords: Retinal Vein and Artery Occlusion, Other: Orbital Cellulitis

Progression of lesion size in untreated eyes with exudative age-related macular degeneration: A meta-analysis using lineweaver-burk plots.

Liu TY, Shah AR, Del Priore LV

JAMA Ophthalmol. 2013 Mar;131(3):335-40

Medical University of South Carolina - Departmental Grant

Keyword: AMD

February, 2013
Early alterations in mitochondrial reserve capacity; a means to predict subsequent photoreceptor cell death.

Perron NR, Beeson C, Rohrer B

J Bioenerg Biomembr. 2013 Feb;45(1-2):101-9

Medical University of South Carolina - Departmental Grant

Keywords: Retinitis Pigmentosa, Other: Retinal Degeneration

January, 2013
C-type natriuretic peptide protects the retinal pigment epithelium against advanced glycation end product-induced barrier dysfunction.

Dahrouj M, Alsarraf O, Liu Y, Crosson CE, Ablonczy Z

J Pharmacol Exp Ther. 2013 Jan;344(1):96-102

Medical University of South Carolina - Departmental Grant

Keywords: Diabetic Retinopathy, Other: Macular Edema

New insights into retinoid metabolism and cycling within the retina.

Tang PH, Kono M, Koutalos Y, Ablonczy Z, Crouch RK

Prog Retin Eye Res. 2013 Jan;32:48-63

Medical University of South Carolina - Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Leber Congenital Amaurosis

The role of the immune response in age-related macular degeneration.

Whitcup SM, Sodhi A, Atkinson JP, Holers VM, Sinha D, Rohrer B, Dick AD

Int J Inflam. 2013;2013:348092

Medical University of South Carolina - Departmental Grant

Keyword: AMD

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