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Research to Prevent Blindness

Research Database

University of Oklahoma Health Sciences Center Research, funded by RPB from 2012-2014 matching Departmental Grant

59 Citations, Sorted by Month and Year

November, 2014
Therapeutic potential of nanoceria in regenerative medicine.

Das S, Chigurupati S, Dowding J, Munusamy P, Baer DR, McGinnis JF, Mattson MP, Self W, Seal S

MRS Bull. 2014 Nov;39(11):976-983.

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: AMD, Diabetic Retinopathy, Glaucoma, Macular Dystrophy

October, 2014
Caveolin-1 increases proinflammatory chemoattractants and blood-retinal barrier breakdown but decreases leukocyte recruitment in inflammation.

Li X, Gu X, Boyce TM, Zheng M, Reagan AM, Qi H, Mandal N, Cohen AW, Callegan MC, Carr, DJ, Elliott MH

Invest Ophthalmol Vis Sci 2014 Oct;55(10): 6224-6234.

University of Oklahoma Health Sciences Center - Special Scholar Award - Mandal, Nawajes / PhD Special Scholar Award - Elliott, Michael H / PhD Departmental Grant

Keywords: AMD, Diabetic Retinopathy, Uveitis/Infectious Diseases

Peroxisome proliferator-activated receptor α protects capillary pericytes in the retina.

Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins AJ, Keech AC, Humphries KM, Gu X, Elliott MH, Xia X, Ma J

Am J Path 2014 Oct;184(10):2709-20.

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Diabetic Retinopathy

September, 2014
Nanoparticle-assisted targeted delivery of eye-specific genes to eyes significantly improves the vision of blind mice in vivo.

Rajala A, Wang Y, Zhu Y, Ranjo-Bishop M, Ma J, Mao C, Rajala RVS

Nano Lett 2014 Sep;14(9):5257-5263.

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Gene Research/Therapy

August, 2014
Ab interno approach to schlemm canal: Ab interno trabecular ablative procedures.

Bailey AK, Vold SD, Sarkisian SR

J Cataract Refract Surg. 2014 Aug;40:1281-1284.

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Glaucoma

June, 2014
Role of TLR5 and flagella in bacillus intraocular infection.

Parkunan SM, Astley R, Callegan MC

PLoS One. 2014 Jun;9(6):e100543.

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Uveitis/Infectious Diseases

May, 2014
Effect of reduced retinal VLC-PUFA on rod and cone photoreceptors.

Bennett LD, Brush RS, Chan M, Lydic TA, Reese K, Reid GE, Busik JV, Elliott MH, Anderson RE

Invest Ophthalmol Vis Sci. 2014 May;55(5):3150-57.

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Macular Dystrophy, AMD

Wiley post, around the world with no stereopsis.

Elshatory YM, Siatkowski RM

Surv Ophthalmol. 2014 May-Jun;59(3):365-372.

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Pediatric, Strabismus/Amblyopia/Eye Movement Disorders

March, 2014
Complications of tube implants and their management.

Bailey AK, Sarkisian SR

Curr Opin Ophthalmol. 2014 Mar;25(2):148-153.

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Glaucoma

Diagnostic and therapeutic challenges.

Elshatory YM, Siatkowski RM, Shah VA, Vajzovic L, Mahmoud TH

Retina 2014 Mar;34(3):618-624.

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Retina/Retinal Diseases

TLR4 contributes to the host response to klebsiella intraocular infection.

Hunt JJ, Astley R, Wheatley N, Wang J, Callegan MC

Curr Eye Res. 2014 Mar;39(8):790-802.

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Uveitis/Infectious Diseases

February, 2014
Factors related to strabismus decompensation after a period of prolonged postoperative stability.

Adler E, Ding K, Siatkowski RM

J AAPOS. 2014 Feb;18(1):50-55.

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Strabismus/Amblyopia/Eye Movement Disorders

Loss of caveolin-1 causes blood-retinal barrier breakdown, venous enlargement, and mural cell alteration.

Gu X, Fliesler SJ, Zhao Y, Stallcup WB, Cohen AW, Elliott MH

Am J Path. 2014 Feb;184(2):541-555.

University of Oklahoma Health Sciences Center - Special Scholar Award - Elliott, Michael H / PhD Departmental Grant

Keywords: Diabetic Retinopathy, Glaucoma, Retinal Vein and Artery Occlusion

January, 2014
Comparison of the american-european consensus group sjӧgren’s syndrome classification criteria to newly proposed american college of rheumatology criteria in a large, carefully characterized sicca cohort.

Rasmussen A, IIce JA, Li H, Grundahl K, Kelly JA, Radfar L, Stone DU, Hefner KS, Anaya J, Rohrer M, Gopalakrishnan R, Houston GD, Lewis DM, Chodosh J, Harley JB, Hughes P, Maier-Moore JS, Montgomery CG, Rhodus NL, Farris AD, Segal BM, Jonsson R, Lessard CJ, Scofield RH, Moser Sivils KL

Ann Rheum Dis. 2014 Jan;73:31-38.

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Dry Eye, Cornea

Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity.

Logan S, Agbaga MP, Chan MD, Brush RS, Anderson RE

J. Lipid Res. 2014;55:698-708.

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Macular Dystrophy, Retina/Retinal Diseases, AMD

Sustained inhibition of neovascularization in vldlr-/-mice following intravitreal injection of cerium oxide nanoparticles and the role of the ASK1-P38/JNK-NF-kappaB pathway.

Cai X, Seal S, McGinnis, JF

Biomaterials. 2014 Jan;35(1):249-258.

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

December, 2013
Ocular surface squamous neoplasia: A survey of changes in the standard of care from 2003 to 2012.

Adler E, Turner JR, Stone DU

Cornea. 2013 Dec;32(12):1558-61

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

November, 2013
Interface haze associated with topical nonsteroidal anti-inflammatory drug use after descemet stripping automated endothelial keratoplasty.

Paul S, Bonkowske JJ, Stone DU

J Ocul Pharmacol Ther. 2013 Nov;29(9):809-11

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

Light activation of the insulin receptor regulates mitochondrial hexokinase.

Rajala A, Gupta VK, Anderson RE, Rajala RV

A possible mechanism of retinal neuroprotection. Mitochondrion. 2013 Nov;13(6):566-76

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Diabetic Retinopathy, Retinitis Pigmentosa

Nanoceria inhibit expression of genes associated with inflammation and angiogenesis in the retina of vldlr null mice.

Kyosseva SV, Chen L, Seal S, McGinnis JF

Exp Eye Res. 2013 Nov;116:63-74

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: AMD, Diabetic Retinopathy, Nanotechnology/Drug Delivery, Retinitis Pigmentosa

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with sjogren's syndrome.

Lessard CJ, Li H, Adrianto I, Ice JA, Rasmussen A, Grundahl KM, Kelly JA, Dozmorov MG, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Goransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnstrom M, Jazebi H, Cunninghame Graham DS, Grandits ME, Nazmul-Hossain AN, Patel K, Adler AJ, Maier-Moore JS, Farris AD, Brennan MT, Lessard JA, Chodosh J, Gopalakrishnan R, Hefner KS, Houston GD, Huang AJ, Hughes PJ, Lewis DM, Radfar L, Rohrer MD, Stone DU, Wren JD, Vyse TJ, Gaffney PM, James JA, Omdal R, Wahren-Herlenius M, Illei GG, Witte T, Jonsson R, Rischmueller M, Ronnblom L, Nordmark G, Ng WF, UK Primary Sjogren's Syndrome Registry, Mariette X, Anaya JM, Rhodus NL, Segal BM, Scofield RH, Montgomery CG, Harley JB, Sivils KL

Nat Genet. 2013 Nov;45(11):1284-92

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

October, 2013
HSV-1 targets lymphatic vessels in the eye and draining lymph node of mice leading to edema in the absence of a functional type I interferon response.

Bryant-Hudson KM, Chucair-Elliott AJ, Conrady CD, Cohen A, Zheng M, Carr DJ

Am J Pathol. 2013 Oct;183(4):1233-42

University of Oklahoma Health Sciences Center - Senior Scientific Investigator Award - Carr, Daniel J J / PhD Departmental Grant

Keyword: Uveitis/Infectious Diseases

September, 2013
Type I interferon and lymphangiogenesis in the HSV-1 infected cornea - are they beneficial to the host?

Bryant-Hudson K, Conrady CD, Carr DJ

Prog Retin Eye Res. 2013 Sep;36:281-91

University of Oklahoma Health Sciences Center - Senior Scientific Investigator Award - Carr, Daniel J J / PhD Departmental Grant

Keyword: Uveitis/Infectious Diseases

July, 2013
Insulin receptor signaling in cones.

Rajala A, Dighe R, Agbaga MP, Anderson RE, Rajala RV

J Biol Chem. 2013 Jul 5;288(27):19503-15

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Diabetic Retinopathy, Retinitis Pigmentosa

June, 2013
Inhibition of de novo ceramide biosynthesis by FTY720 protects rat retina from light-induced degeneration.

Chen H, Tran JT, Eckerd A, Huynh TP, Elliott MH, Brush RS, Mandal NA

J Lipid Res. 2013 Jun;54(6):1616-29

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Retina/Retinal Diseases, Retinitis Pigmentosa

May, 2013
Specific sphingolipid content decrease in cerkl knockdown mouse retinas.

Garanto A, Mandal NA, Egido-Gabas M, Marfany G, Fabrias G, Anderson RE, Casas J, Gonzalez-Duarte R

Exp Eye Res. 2013 May;110:96-106

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Retina/Retinal Diseases, Retinitis Pigmentosa

Stromal melting associated with a cosmetic contact lens over a boston keratoprosthesis: Treatment with a conjunctival flap.

Adesina OO, Vickery JA, Ferguson CL, Stone DU

Eye Contact Lens. 2013 May;39(3):e4-6

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

April, 2013
Deciphering mutant ELOVL4 activity in autosomal-dominant stargardt macular dystrophy.

Logan S, Agbaga MP, Chan MD, Kabir N, Mandal NA, Brush RS, Anderson RE

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5446-51

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Macular Dystrophy, Retina/Retinal Diseases

March, 2013
A novel translocation t(11;13) (q21;q14.2) in a child with suprasellar primitive neuroectodermal tumor and retinoblastoma.

Huddleston S, McNall-Knapp RY, Siatkowski M, Odom C, Brennan R, Wilson MW

Ophthalmic Genet. 2013 Mar-Jun;34(1-2):97-100

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Gene Research/Therapy, Ocular Oncology/Pterygium, Retina/Retinal Diseases

Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitis.

Conrady CD, Zheng M, van Rooijen N, Drevets DA, Royer D, Alleman A, Carr DJ

J Immunol. 2013 Mar 15;190(6):2807-17

University of Oklahoma Health Sciences Center - Senior Scientific Investigator Award - Carr, Daniel J J / PhD Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

Protein tyrosine phosphatase-1B regulates the tyrosine phosphorylation of the adapter Grb2-associated binder 1 (Gab1) in the retina.

Rajala A, Dilly AK, Rajala RV

Cell Commun Signal. 2013 Mar 22;11(1):20

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Retinitis Pigmentosa

January, 2013
Botanical compounds: Effects on major eye diseases.

Huynh TP, Mann SN, Mandal NA

Evid Based Complement Alternat Med. 2013;2013:549174

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: AMD, Cataract, Diabetic Retinopathy, Glaucoma

Catalytic nanoceria are preferentially retained in the rat retina and are not cytotoxic after intravitreal injection.

Wong LL, Hirst SM, Pye QN, Reilly CM, Seal S, McGinnis JF

PLoS One. 2013;8(3):e58431

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: AMD, Diabetic Retinopathy, Nanotechnology/Drug Delivery, Retinitis Pigmentosa

Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene.

Mandal NA, Tran JT, Saadi A, Rahman AK, Huynh TP, Klein WH, Cho JH

Exp Eye Res. 2013 Jan;106:24-33

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Retina/Retinal Diseases, Retinitis Pigmentosa

IFN-alpha-driven CCL2 production recruits inflammatory monocytes to infection site in mice.

Conrady CD, Zheng M, Mandal NA, van Rooijen N, Carr DJ

Mucosal Immunol. 2013 Jan;6(1):45-55

University of Oklahoma Health Sciences Center - Senior Scientific Investigator Award - Carr, Daniel J J / PhD Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

December, 2012
Sustained protection against photoreceptor degeneration in tubby mice by intravitreal injection of nanoceria.

Cai X, Sezate SA, Seal S, McGinnis JF

Biomaterials. 2012 Dec;33(34):8771-81

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Gene Research/Therapy, Nanotechnology/Drug Delivery, Retina/Retinal Diseases, Retinitis Pigmentosa

November, 2012
The diabetic ocular environment facilitates the development of endogenous bacterial endophthalmitis.

Coburn PS, Wiskur BJ, Christy E, Callegan MC

Invest Ophthalmol Vis Sci. 2012 Nov 1;53(12):7426-31

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Retina/Retinal Diseases, Uveitis/Infectious Diseases

October, 2012
CXCL1-deficient mice are highly sensitive to pseudomonas aeruginosa but not herpes simplex virus type 1 corneal infection.

Bryant-Hudson KM, Carr DJ

Invest Ophthalmol Vis Sci. 2012 Oct 1;53(11):6785-92

University of Oklahoma Health Sciences Center - Senior Scientific Investigator Award - Carr, Daniel J J / PhD Departmental Grant

Keyword: Cornea

Effect of the physician quality reporting initiative on ophthalmologists' documentation of practice patterns.

Nikpoor N, Butt AL, Hromas AR, Stone DU

Arch Ophthalmol. 2012 Oct 1;130(10):1351-2

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Other: Healthcare Systems

Metastatic lung adenocarcinoma to the iris mimicking cogan-reese syndrome.

Harvey BJ, Grossniklaus HE, Traynor MP, Sarkisian SR, Stone DU

J Glaucoma. 2012 Oct-Nov;21(8):567-9

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Cornea, Glaucoma

September, 2012
Clinicopathologic findings in iridocorneal endothelial syndrome and posterior polymorphous membranous dystrophy after descemet stripping automated endothelial keratoplasty.

Bromley JG, Randleman JB, Stone D, Stulting RD, Grossniklaus HE

Cornea. 2012 Sep;31(9):1060-4

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Cornea, Other: Ocular Pathology

Prevalence of diabetes mellitus in biopsy-positive giant cell arteritis.

Matthews JL, Gilbert DN, Farris BK, Siatkowski RM

J Neuroophthalmol. 2012 Sep;32(3):202-6

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Neuro-Ophthalmology

Relation of sensory peripheral neuropathy in sjogren syndrome to anti-Ro/SSA.

Scofield AK, Radfar L, Ice JA, Vista E, Anaya JM, Houston G, Lewis D, Stone DU, Chodosh J, Hefner K, Lessard CJ, Moser KL, Scofield RH

J Clin Rheumatol. 2012 Sep;18(6):290-3

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

July, 2012
CD8+ T cells suppress viral replication in the cornea but contribute to VEGF-C-induced lymphatic vessel genesis.

Conrady CD, Zheng M, Stone DU, Carr DJ

J Immunol. 2012 Jul 1;189(1):425-32

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

Comparison of the host immune response to herpes simplex virus 1 (HSV-1) and HSV-2 at two different mucosal sites.

Zheng M, Conrady CD, Ward JM, Bryant-Hudson KM, Carr DJ

J Virol. 2012 Jul;86(13):7454-8

University of Oklahoma Health Sciences Center - Senior Scientific Investigator Award - Carr, Daniel J J / PhD Departmental Grant

Keyword: Cornea

Leukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium.

Chucair-Elliott AJ, Elliott MH, Wang J, Moiseyev GP, Ma JX, Politi LE, Rotstein NP, Akira S, Uematsu S, Ash JD

J Biol Chem. 2012 Jul 13;287(29):24092-102

University of Oklahoma Health Sciences Center - Special Scholar Award - Elliott, Michael H / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

Oxidative and endoplasmic reticulum stresses mediate apoptosis induced by modified LDL in human retinal muller cells.

Wu M, Yang S, Elliott MH, Fu D, Wilson K, Zhang J, Du M, Chen J, Lyons T

Invest Ophthalmol Vis Sci. 2012 Jul 9;53(8):4595-604

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Retina/Retinal Diseases

May, 2012
Loss of caveolin-1 impairs retinal function due to disturbance of subretinal microenvironment.

Li X, McClellan ME, Tanito M, Garteiser P, Towner R, Bissig D, Berkowitz BA, Fliesler SJ, Woodruff ML, Fain GL, Birch DG, Khan MS, Ash JD, Elliott MH

J Biol Chem. 2012 May 11;287(20):16424-34

University of Oklahoma Health Sciences Center - Special Scholar Award - Elliott, Michael H / PhD Departmental Grant

Keyword: Retina/Retinal Diseases

March, 2012
ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3.

Yu M, Benham A, Logan S, Brush RS, Mandal MN, Anderson RE, Agbaga MP

J Lipid Res. 2012 Mar;53(3):494-504

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: AMD, Macular Dystrophy, Retina/Retinal Diseases, Retinitis Pigmentosa

Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16.

Conrady CD, Zheng M, Fitzgerald KA, Liu C, Carr DJ

Mucosal Immunol. 2012 Mar;5(2):173-83

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

February, 2012
Changes in the prevalence of visual impairment due to blinding trachoma in sichuan province, china: A comparative study between 1987 and 2006.

Chen H, Wu X, Wei M, Eichner JE, Fan Y, Zhang Z, Lei C, Stone DU, Yang J

Ophthalmic Epidemiol. 2012 Feb;19(1):29-37

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Cornea, Epidemiology

Effect of the oxygen saturation target on clinical characteristics of early- versus late-onset retinopathy of prematurity.

Tlucek PS, Grace SF, Anderson MP, Siatkowski RM

J AAPOS. 2012 Feb;16(1):70-4

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Pediatric, Retina/Retinal Diseases

Intermediate term safety and efficacy of transscleral cyclophotocoagulation after tube shunt failure.

Ness PJ, Khaimi MA, Feldman RM, Tabet R, Sarkisian SR,Jr, Skuta GL, Chuang AZ, Mankiewicz KA

J Glaucoma. 2012 Feb;21(2):83-8

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Glaucoma

January, 2012
A multicenter study to map genes for fuchs endothelial corneal dystrophy: Baseline characteristics and heritability.

Louttit MD, Kopplin LJ, Igo RP,Jr, Fondran JR, Tagliaferri A, Bardenstein D, Aldave AJ, Croasdale CR, Price MO, Rosenwasser GO, Lass JH, Iyengar SK, FECD Genetics Multi-Center Study Group

Cornea. 2012 Jan;31(1):26-35

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

A twisted mess.

Tlucek PS, Moreau A, Siatkowski RM, Repka MX

Surv Ophthalmol. 2012 Jan-Feb;57(1):77-82

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: Pediatric, Retina/Retinal Diseases

Caffeic acid phenethyl ester protects 661W cells from H2O2-mediated cell death and enhances electroretinography response in dim-reared albino rats.

Chen H, Tran JT, Anderson RE, Mandal MN

Mol Vis. 2012;18:1325-38

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases, Retinitis Pigmentosa

Certolizumab pegol therapy for rheumatoid arthritis-associated scleritis.

Tlucek PS, Stone DU

Cornea. 2012 Jan;31(1):90-1

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

Oxidative stress: The achilles' heel of neurodegenerative diseases of the retina.

Cai X, McGinnis JF

Front Biosci. 2012 Jan 1;17:1976-95

University of Oklahoma Health Sciences Center - Departmental Grant

Keywords: AMD, Diabetic Retinopathy, Retina/Retinal Diseases, Retinitis Pigmentosa

PD-L1-expressing dendritic cells contribute to viral resistance during acute HSV-1 infection.

Bryant-Hudson KM, Carr DJ

Clin Dev Immunol. 2012;2012:924619

University of Oklahoma Health Sciences Center - Departmental Grant

Keyword: Cornea

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