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Research to Prevent Blindness

Research Database

Louisiana State University Research, funded by RPB from 2010-2014 matching Departmental Grant

49 Citations, Sorted by Month and Year

November, 2014
An evaluation of progressive amyloidogenic and pro-inflammatory change in the primary visual cortex and retina in alzheimer's disease (AD).

Hill JM, Dua P, Clement C, Lukiw WJ

Front Neurosci. 2014 Nov 12;8:347

Louisiana State University - Departmental Grant

Keyword: Retina/Retinal Diseases

September, 2014
Beta-amyloid precursor protein (betaAPP) processing in alzheimer's disease (AD) and age-related macular degeneration (AMD).

Zhao Y, Bhattacharjee S, Jones BM, Hill JM, Clement C, Sambamurti K, Dua P, Lukiw WJ

Mol Neurobiol. 2014 Sep 10

Louisiana State University - Departmental Grant

Keyword: AMD

Synthesis and antifungal activity of substituted salicylaldehyde hydrazones, hydrazides and sulfohydrazides.

Backes GL, Neumann DM, Jursic BS

Bioorg Med Chem. 2014 Sep 1;22(17):4629-36

Louisiana State University - Departmental Grant

Keywords: Nanotechnology/Drug Delivery, Uveitis/Infectious Diseases

July, 2014
Rescue of enzymatic function for disease-associated RPE65 proteins containing various missense mutations in non-active sites.

Li S, Izumi T, Hu J, Jin HH, Siddiqui AA, Jacobson SG, Bok D, Jin M

J Biol Chem. 2014 Jul 4;289(27):18943-56

Louisiana State University - Departmental Grant

Keywords: Gene Research/Therapy, Retina/Retinal Diseases, Retinitis Pigmentosa

June, 2014
Development and evaluation of SYBR green-I based quantitative PCR assays for herpes simplex virus type 1 whole transcriptome analysis.

Garvey CE, McGowin CL, Foster TP

J Virol Methods. 2014 Jun;201:101-11

Louisiana State University - Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

March, 2014
Spatial organization of lipids in the human retina and optic nerve by MALDI imaging mass spectrometry.

Zemski Berry KA, Gordon WC, Murphy RC, Bazan NG

J Lipid Res. 2014 Mar;55(3):504-15

Louisiana State University - Departmental Grant

Keyword: Retina/Retinal Diseases

January, 2014
Differential effects of hepatocyte growth factor and keratinocyte growth factor on corneal epithelial cell cycle protein expression, cell survival, and growth.

Chandrasekher G, Pothula S, Maharaj G, Bazan HE

Mol Vis. 2014 Jan 6;20:24-37

Louisiana State University - Departmental Grant

Keyword: Cornea

Synthesis and antifungal activity of substituted 2,4,6-pyrimidinetrione carbaldehyde hydrazones.

Neumann DM, Cammarata A, Backes G, Palmer GE, Jursic BS

Bioorg Med Chem. 2014 Jan 15;22(2):813-26

Louisiana State University - Departmental Grant

Keywords: Nanotechnology/Drug Delivery, Uveitis/Infectious Diseases

October, 2013
Mediator lipidomics in ophthalmology: Targets for modulation in inflammation, neuroprotection and nerve regeneration.

Gordon WC, Bazan NG

Curr Eye Res. 2013 Oct;38(10):995-1005

Louisiana State University - Departmental Grant

Keywords: Neuro-Ophthalmology, Retina/Retinal Diseases

Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein.

Sato K, Li S, Gordon WC, He J, Liou GI, Hill JM, Travis GH, Bazan NG, Jin M

J Neurosci. 2013 Oct 30;33(44):17458-68

Louisiana State University - Departmental Grant

Keyword: Retina/Retinal Diseases

The antimicrobial agent C31G is effective for therapy for HSV-1 ocular keratitis in the rabbit eye model.

Hill JM, Stern EM, Bhattacharjee PS, Malamud D, Clement C, Rodriguez P, Lukiw WJ, Ochoa AC, Foster TP, Velasco C, McFerrin HE,Jr

Antiviral Res. 2013 Oct;100(1):14-9

Louisiana State University - Departmental Grant

Keyword: Cornea

The TFOS international workshop on contact lens discomfort: Report of the definition and classification subcommittee.

Nichols KK, Redfern RL, Jacob JT, Nelson JD, Fonn D, Forstot SL, Huang JF, Holden BA, Nichols JJ, members of the TFOS International Workshop on Contact Lens Discomfort

Invest Ophthalmol Vis Sci. 2013 Oct 18;54(11):TFOS14-9

Louisiana State University - Departmental Grant

Keywords: Cornea, Dry Eye

August, 2013
Microglial ramification and redistribution concomitant with the attenuation of choroidal neovascularization by neuroprotectin D1.

Sheets KG, Jun B, Zhou Y, Zhu M, Petasis NA, Gordon WC, Bazan NG

Mol Vis. 2013 Aug 4;19:1747-59

Louisiana State University - Departmental Grant

Keyword: Retina/Retinal Diseases

June, 2013
Neuroprotectin D1 restores corneal nerve integrity and function after damage from experimental surgery.

Cortina MS, He J, Russ T, Bazan NG, Bazan HE

Invest Ophthalmol Vis Sci. 2013 Jun 12;54(6):4109-16

Louisiana State University - Departmental Grant

Keyword: Cornea

April, 2013
Corneal neovascularization: A review of the molecular biology and current therapies.

Rolfsen M, Frisard N, Stern E, Foster T, Bhattacharjee P, McFerrin H, Clement C, Rodriguez P, Lukiw W, Bergsma D, Ochoa A, Hill J

Expert Rev Ophthalmol. 2013 Apr;8(2):167-89

Louisiana State University - Departmental Grant

Keyword: Cornea

Secretory defect and cytotoxicity: The potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP).

Li S, Yang Z, Hu J, Gordon WC, Bazan NG, Haas AL, Bok D, Jin M

J Biol Chem. 2013 Apr 19;288(16):11395-406

Louisiana State University - Departmental Grant

Keyword: Retinitis Pigmentosa

March, 2013
A reduced zinc diet or zinc transporter 3 knockout attenuate light induced zinc accumulation and retinal degeneration.

Bai S, Sheline CR, Zhou Y, Sheline CT

Exp Eye Res. 2013 Mar;108:59-67

Louisiana State University - Departmental Grant

Keyword: Retina/Retinal Diseases

February, 2013
The UBIAD1 prenyltransferase links menaquinone-4 [corrected] synthesis to cholesterol metabolic enzymes.

Nickerson ML, Bosley AD, Weiss JS, Kostiha BN, Hirota Y, Brandt W, Esposito D, Kinoshita S, Wessjohann L, Morham SG, Andresson T, Kruth HS, Okano T, Dean M

Hum Mutat. 2013 Feb;34(2):317-29

Louisiana State University - Departmental Grant

Keyword: Cornea

January, 2013
Biocompatibility in the development of silicone-hydrogel lenses.

Jacob JT

Eye Contact Lens. 2013 Jan;39(1):13-9

Louisiana State University - Departmental Grant

Keyword: Cornea

Corneal nerve architecture in a donor with unilateral epithelial basement membrane dystrophy.

He J, Bazan HE

Ophthalmic Res. 2013;49(4):185-91

Louisiana State University - Departmental Grant

Keyword: Cornea

December, 2012
CTCF occupation of the herpes simplex virus 1 genome is disrupted at early times postreactivation in a transcription-dependent manner.

Ertel MK, Cammarata AL, Hron RJ, Neumann DM

J Virol. 2012 Dec;86(23):12741-59

Louisiana State University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

October, 2012
Lipoxin A(4) inhibits platelet-activating factor inflammatory response and stimulates corneal wound healing of injuries that compromise the stroma.

Kakazu A, He J, Kenchegowda S, Bazan HE

Exp Eye Res. 2012 Oct;103:9-16

Louisiana State University - Departmental Grant

Keyword: Cornea

September, 2012
HSV-1 latent rabbits shed viral DNA into their saliva.

Hill JM, Nolan NM, McFerrin HE, Clement C, Foster TP, Halford WP, Kousoulas KG, Lukiw WJ, Thompson HW, Stern EM, Bhattacharjee PS

Virol J. 2012 Sep 28;9:221

Louisiana State University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

August, 2012
Neuroinflammation and proteostasis are modulated by endogenously biosynthesized neuroprotectin D1.

Bazan NG

Mol Neurobiol. 2012 Aug;46(1):221-6

Louisiana State University - Departmental Grant

Keywords: AMD, Retinitis Pigmentosa

July, 2012
Ataxin-1 poly(Q)-induced proteotoxic stress and apoptosis are attenuated in neural cells by docosahexaenoic acid-derived neuroprotectin D1.

Calandria JM, Mukherjee PK, de Rivero Vaccari JC, Zhu M, Petasis NA, Bazan NG

J Biol Chem. 2012 Jul 6;287(28):23726-39

Louisiana State University - Departmental Grant

Keyword: Cornea

Ganciclovir ophthalmic gel 0.15%: Safety and efficacy of a new treatment for herpes simplex keratitis.

Kaufman HE, Haw WH

Curr Eye Res. 2012 Jul;37(7):654-60

Louisiana State University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

June, 2012
Franceschetti hereditary recurrent corneal erosion.

Lisch W, Bron AJ, Munier FL, Schorderet DF, Tiab L, Lange C, Saikia P, Reinhard T, Weiss JS, Gundlach E, Pleyer U, Lisch C, Auw-Haedrich C

Am J Ophthalmol. 2012 Jun;153(6):1073-81.e4

Louisiana State University - Departmental Grant

Keyword: Cornea

NF-small ka, CyrillicB-regulated micro RNAs (miRNAs) in primary human brain cells.

Lukiw WJ

Exp Neurol. 2012 Jun;235(2):484-90

Louisiana State University - Departmental Grant

Keyword: Retina/Retinal Diseases

Visualizing hydrophobic domains in silicone hydrogel lenses with sudan IV.

Jacob JT, Levet J,Jr, Edwards TA, Dassanayake N, Ketelson H

Invest Ophthalmol Vis Sci. 2012 Jun 8;53(7):3473-80

Louisiana State University - Departmental Grant

Keywords: Cornea, Other: Contact Lenses

May, 2012
Mapping the nerve architecture of diabetic human corneas.

He J, Bazan HE

Ophthalmology. 2012 May;119(5):956-64

Louisiana State University - Departmental Grant

Keyword: Cornea

January, 2012
Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in alzheimer's disease (AD) and in age-related macular degeneration (AMD).

Lukiw WJ, Surjyadipta B, Dua P, Alexandrov PN

Int J Biochem Mol Biol. 2012;3(1):105-16

Louisiana State University - Departmental Grant

Keyword: AMD

Rabbit and mouse models of HSV-1 latency, reactivation, and recurrent eye diseases.

Webre JM, Hill JM, Nolan NM, Clement C, McFerrin HE, Bhattacharjee PS, Hsia V, Neumann DM, Foster TP, Lukiw WJ, Thompson HW

J Biomed Biotechnol. 2012;2012:612316

Louisiana State University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

December, 2011
Antifungal activity of 2alpha,3beta-functionalized steroids stereoselectively increases with the addition of oligosaccharides.

Cammarata A, Upadhyay SK, Jursic BS, Neumann DM

Bioorg Med Chem Lett. 2011 Dec 15;21(24):7379-86

Louisiana State University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

November, 2011
Descemetic versus pre-descemetic lamellar keratoplasty: Clinical and confocal study.

Abdelkader A, Kaufman HE

Cornea. 2011 Nov;30(11):1244-52

Louisiana State University - Departmental Grant

Keyword: Cornea Transplants

August, 2011
Ocular herpes simplex virus: How are latency, reactivation, recurrent disease and therapy interrelated?

Al-Dujaili LJ, Clerkin PP, Clement C, McFerrin HE, Bhattacharjee PS, Varnell ED, Kaufman HE, Hill JM

Future Microbiol. 2011 Aug;6(8):877-907

Louisiana State University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

May, 2011
Lytic HSV-1 infection induces the multifunctional transcription factor early growth response-1 (EGR-1) in rabbit corneal cells.

Bedadala GR, Palem JR, Graham L, Hill JM, McFerrin HE, Hsia SC

Virol J. 2011 May 27;8:262

Louisiana State University - Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

Synthesis and antifungal activity of functionalized 2,3-spirostane isomers.

Upadhyay SK, Creech CC, Bowdy KL, Stevens ED, Jursic BS, Neumann DM

Bioorg Med Chem Lett. 2011 May 15;21(10):2826-31

Louisiana State University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

April, 2011
Enhanced oxygen saturation in optic nerve head of non-human primate eyes following the intravitreal injection of NCX 434, an innovative nitric oxide-donating glucocorticoid.

Khoobehi B, Chiroli V, Ronchetti D, Miglietta D, Thompson H, Ongini E, Impagnatiello F

J Ocul Pharmacol Ther. 2011 Apr;27(2):115-21

Louisiana State University - Departmental Grant

Keyword: Diabetic Retinopathy

March, 2011
Ocular herpes simplex virus type 1: Is the cornea a reservoir for viral latency or a fast pit stop?

Kennedy DP, Clement C, Arceneaux RL, Bhattacharjee PS, Huq TS, Hill JM

Cornea. 2011 Mar;30(3):251-9

Louisiana State University - Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

Upregulation of mouse genes in HSV-1 latent TG after butyrate treatment implicates the multiple roles of the LAT-ICP0 locus.

Clement C, Bhattacharjee PS, Kumar M, Foster TP, Thompson HW, Hill JM

Invest Ophthalmol Vis Sci. 2011 Mar 28;52(3):1770-9

Louisiana State University - Departmental Grant

Keywords: Gene Research/Therapy, Uveitis/Infectious Diseases

February, 2011
In vitro synergism of trifluorothymidine and ganciclovir against HSV-1.

Hobden JA, Kumar M, Kaufman HE, Clement C, Varnell ED, Bhattacharjee PS, Hill JM

Invest Ophthalmol Vis Sci. 2011 Feb 11;52(2):830-3

Louisiana State University - Departmental Grant

Keyword: Uveitis/Infectious Diseases

January, 2011
A novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesis.

Bhattacharjee PS, Huq TS, Mandal TK, Graves RA, Muniruzzaman S, Clement C, McFerrin HE, Hill JM

PLoS One. 2011 Jan 6;6(1):e15905

Louisiana State University - Departmental Grant

Keyword: Ocular Oncology Melanoma

Clinical and antiviral efficacy of an ophthalmic formulation of dexamethasone povidone-iodine in a rabbit model of adenoviral keratoconjunctivitis.

Clement C, Capriotti JA, Kumar M, Hobden JA, Foster TP, Bhattacharjee PS, Thompson HW, Mahmud R, Liang B, Hill JM

Invest Ophthalmol Vis Sci. 2011 Jan 21;52(1):339-44

Louisiana State University - Departmental Grant

Keywords: Cornea, Uveitis/Infectious Diseases

Increased expression of miRNA-146a in alzheimer's disease transgenic mouse models.

Li YY, Cui JG, Hill JM, Bhattacharjee S, Zhao Y, Lukiw WJ

Neurosci Lett. 2011 Jan 3;487(1):94-8

Louisiana State University - Departmental Grant

Keyword: Gene Research/Therapy

January, 2010
Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells.

Lukiw WJ, Cui JG, Yuan LY, Bhattacharjee PS, Cockern M, Clement C, Kammerman EM, Ball MJ, Zhao Y, Sullivan PM, Hill JM

Neuroreport 2010;21(14):922-927

Louisiana State University - Departmental Grant

Keywords: Gene Research/Therapy, Uveitis/Infectious Diseases

Changes to euchromatin on LAT and ICP4 following reactivation are more prevalent in an efficiently reactivating strain of HSV-1.

Creech CC, Neumann DM

PLoS ONE 2010:5(11):e15416

Louisiana State University - Departmental Grant

Keywords: Gene Research/Therapy, Uveitis/Infectious Diseases

Confocal microscopy of corneal wound healing after deep lamellar keratoplasty in rabbits.

Abdelkader A, Elewah el-SM, Kaufman HE

Arch Ophthalmol 2010;128(1):75-80

Louisiana State University - Departmental Grant

Keyword: Cornea Transplants

Effect of high versus low oral doses of valacyclovir on herpes simplex virus-1 DNA shedding into tears of latently infected rabbits.

Kumar M, Kaufman HE, Clement C, Bhattacharjee PS, Huq T, Varnell ED, Thompson HW, Hill JM

Invest Ophthalmol Vis Sci 2010;51(9):4703-4706

Louisiana State University - Departmental Grant

Keywords: Gene Research/Therapy, Uveitis/Infectious Diseases

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