netbook
desktop
mobile
tablet-landscape
tablet
phone-landscape
phone
Research to Prevent Blindness

Research Database

University of Kentucky Research, funded by RPB from 2012-2014 matching Departmental Grant

9 Citations, Sorted by Month and Year

November, 2014
DICER1/Alu RNA dysmetabolism induces caspase-8-mediated cell death in age-related macular degeneration.

Kim Y, Tarallo V, Kerur N, Yasuma T, Gelfand BD, Bastos-Carvalho A, Hirano Y, Yasuma R, Mizutani T, Fowler BJ, Li S, Kaneko H, Bogdanovich S, Ambati BK, Hinton DR, Hauswirth WW, Hakem R, Wright C, Ambati J

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16082-7

University of Kentucky - Departmental Grant

Keywords: AMD, Other: Dicer1

Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity.

Fowler BJ, Gelfand BD, Kim Y, Kerur N, Tarallo V, Hirano Y, Amarnath S, Fowler DH, Radwan M, Young MT, Pittman K, Kubes P, Agarwal HK, Parang K, Hinton DR, Bastos-Carvalho A, Li S, Yasuma T, Mizutani T, Yasuma R, Wright C, Ambati J

Science. 2014 Nov 21;346(6212):1000-3

University of Kentucky - Departmental Grant

Keyword: Other: Nucleoside Reverse Transcriptase Inhibitors

November, 2013
TLR-independent and P2X7-dependent signaling mediate alu RNA-induced NLRP3 inflammasome activation in geographic atrophy.

Kerur N, Hirano Y, Tarallo V, Fowler BJ, Bastos-Carvalho A, Yasuma T, Yasuma R, Kim Y, Hinton DR, Kirschning CJ, Gelfand BD, Ambati J

Invest Ophthalmol Vis Sci. 2013 Nov 11;54(12):7395-401

University of Kentucky - Departmental Grant

Keyword: AMD

October, 2013
Retinal angiogenesis suppression through small molecule activation of p53.

Chavala SH, Kim Y, Tudisco L, Cicatiello V, Milde T, Kerur N, Claros N, Yanni S, Guaiquil VH, Hauswirth WW, Penn JS, Rafii S, De Falco S, Lee TC, Ambati J

J Clin Invest. 2013 Oct 1;123(10):4170-81

University of Kentucky - Departmental Grant

Keyword: AMD

June, 2013
Immunology of age-related macular degeneration.

Ambati J, Atkinson JP, Gelfand BD

Nat Rev Immunol. 2013 Jun;13(6):438-51

University of Kentucky - Departmental Grant

Keyword: AMD

January, 2013
Clocking in on diabetic retinopathy.

Kleinman ME, Ambati J

Diabetes. 2013 Jan;62(1):29-30

University of Kentucky - Career Development Award - Kleinman, Mark E / MD Departmental Grant

Keyword: Diabetic Retinopathy

August, 2012
ERK1/2 activation is a therapeutic target in age-related macular degeneration.

Dridi S, Hirano Y, Tarallo V, Kim Y, Fowler BJ, Ambati BK, Bogdanovich S, Chiodo VA, Hauswirth WW, Kugel JF, Goodrich JA, Ponicsan SL, Hinton DR, Kleinman ME, Baffi JZ, Gelfand BD, Ambati J

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13781-6

University of Kentucky - Departmental Grant

Keyword: AMD

January, 2012
A window to innate neuroimmunity: Toll-like receptor-mediated cell responses in the retina.

Kleinman ME, Ambati J

Adv Exp Med Biol. 2012;723:3-9

University of Kentucky - Departmental Grant

Keyword: AMD

Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.

Kleinman ME, Kaneko H, Cho WG, Dridi S, Fowler BJ, Blandford AD, Albuquerque RJ, Hirano Y, Terasaki H, Kondo M, Fujita T, Ambati BK, Tarallo V, Gelfand BD, Bogdanovich S, Baffi JZ, Ambati J

Mol Ther. 2012 Jan;20(1):101-8

University of Kentucky - Departmental Grant

Keyword: AMD

Subscribe

Get our email updates filled with the latest news from our researchers about preventing vision loss, treating eye disease and even restoring sight. Unsubscribe at any time. Under our privacy policy, we'll never share your contact information with a third party.

Follow Us