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Research to Prevent Blindness

Research Database

Cleveland Clinic Lerner College of Medicine Research, funded by RPB from 2010-2014 matching Departmental Grant

179 Citations, Sorted by Month and Year

December, 2014
Assessment of retinal alterations after intravitreal ocriplasmin with spectral-domain optical coherence tomography.

Itoh Y, Kaiser PK, Singh RP, Srivastava SK, Ehlers JP

Ophthalmology. 2014 Dec;121(12):2506,2507.e2

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Retina/Retinal Diseases

Cellular and extracellular matrix modulation of corneal stromal opacity.

Torricelli AA, Wilson SE

Exp Eye Res. 2014 Dec;129:151-60

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Other: Wound Healing

Detection and biological activities of carboxyethylpyrrole ethanolamine phospholipids (CEP-EPs).

Wang H, Guo J, West XZ, Bid HK, Lu L, Hong L, Jang GF, Zhang L, Crabb JW, Clinical Genomic and Proteomic AMD Study Group, Linetsky M, Salomon RG

Chem Res Toxicol. 2014 Dec 15;27(12):2015-22

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

Does genetic variation influence response to treatment with vascular endothelial growth factor inhibitors in neovascular age-related macular degeneration?

Chakravarthy U, Hagstrom SA

Ophthalmic Epidemiol. 2014 Dec;21(6):345-6

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Gene Research/Therapy

Retinal vasculature of adult zebrafish: In vivo imaging using confocal scanning laser ophthalmoscopy.

Bell BA, Xie J, Yuan A, Kaul C, Hollyfield JG, Anand-Apte B

Exp Eye Res. 2014 Dec;129:107-18

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Imaging

Simultaneous assessment of glomerular filtration and barrier function in live zebrafish.

Kotb AM, Muller T, Xie J, Anand-Apte B, Endlich K, Endlich N

Am J Physiol Renal Physiol. 2014 Dec 15;307(12):F1427-34

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Other: Retinal Cell Biology

November, 2014
Collateral vessel presence in branch and central retinal vein occlusions and their impact on visual acuity and anatomical gains: A retrospective analysis.

Singh RP, Lee TJ, Yau L, Rubio RG

Retina. 2014 Nov;34(11):2242-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retinal Vein and Artery Occlusion

Gaze holding after anterior-inferior temporal lobectomy.

Shaikh AG, Ghasia FF

Neurol Sci. 2014 Nov;35(11):1749-56

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Neuro-Ophthalmology

Rare and common variants in extracellular matrix gene fibrillin 2 (FBN2) are associated with macular degeneration.

Ratnapriya R, Zhan X, Fariss RN, Branham KE, Zipprer D, Chakarova CF, Sergeev YV, Campos MM, Othman M, Friedman JS, Maminishkis A, Waseem NH, Brooks M, Rajasimha HK, Edwards AO, Lotery A, Klein BE, Truitt BJ, Li B, Schaumberg DA, Morgan DJ, Morrison MA, Souied E, Tsironi EE, Grassmann F, Fishman GA, Silvestri G, Scholl HP, Kim IK, Ramke J, Tuo J, Merriam JE, Merriam JC, Park KH, Olson LM, Farrer LA, Johnson MP, Peachey NS, Lathrop M, Baron RV, Igo RP,Jr, Klein R, Hagstrom SA, Kamatani Y, Martin TM, Jiang Y, Conley Y, Sahel JA, Zack DJ, Chan CC, Pericak-Vance MA, Jacobson SG, Gorin MB, Klein ML, Allikmets R, Iyengar SK, Weber BH, Haines JL, Leveillard T, Deangelis MM, Stambolian D, Weeks DE, Bhattacharya SS, Chew EY, Heckenlively JR, Abecasis GR, Swaroop A

Hum Mol Genet. 2014 Nov 1;23(21):5827-37

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

The prospective intraoperative and perioperative ophthalmic ImagiNg with optical CoherEncE TomogRaphy (PIONEER) study: 2-year results.

Ehlers JP, Dupps WJ, Kaiser PK, Goshe J, Singh RP, Petkovsek D, Srivastava SK

Am J Ophthalmol. 2014 Nov;158(5):999-1007

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Imaging, Retina/Retinal Diseases

October, 2014
A protective eye shield for prevention of media opacities during small animal ocular imaging.

Bell BA, Kaul C, Hollyfield JG

Exp Eye Res. 2014 Oct;127:280-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cataract, Imaging

Intraoperative optical coherence tomography using the RESCAN 700: Preliminary results from the DISCOVER study.

Ehlers JP, Kaiser PK, Srivastava SK

Br J Ophthalmol. 2014 Oct;98(10):1329-32

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Optical Coherence Tomography

Retinal infiltrates secondary to metastatic squamous cell carcinoma masquerading as infectious retinitis.

Singh RP, Steinle NC, Bedi R, Kaiser P, Lowder CY

Retin Cases Brief Rep. 2014 Fall;8(4):333-5

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Ocular Oncology/Pterygium, Retina/Retinal Diseases

Screening of refractive surgery candidates for LASIK and PRK.

Torricelli AA, Bechara SJ, Wilson SE

Cornea. 2014 Oct;33(10):1051-5

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Selective impairment of a subset of ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

Patil H, Saha A, Senda E, Cho KI, Haque M, Yu M, Qiu S, Yoon D, Hao Y, Peachey NS, Ferreira PA

J Biol Chem. 2014 Oct 24;289(43):29767-89

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

The effects of surgical factors on postoperative astigmatism in patients enrolled in the infant aphakia treatment study (IATS).

Wall PB, Lee JA, Lynn MJ, Lambert SR, Traboulsi EI, Infant Aphakia Treatment Study Group

J AAPOS. 2014 Oct;18(5):441-5

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Pediatric

September, 2014
Retinal and nonocular abnormalities in Cyp27a1(-/-)Cyp46a1(-/-) mice with dysfunctional metabolism of cholesterol.

Saadane A, Mast N, Charvet CD, Omarova S, Zheng W, Huang SS, Kern TS, Peachey NS, Pikuleva IA

Am J Pathol. 2014 Sep;184(9):2403-19

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Retinal histopathology in eyes from a patient with stargardt disease caused by compound heterozygous ABCA4 mutations.

Bonilha VL, Rayborn ME, Bell BA, Marino MJ, Fishman GA, Hollyfield JG

Ophthalmic Genet. 2014 Sep 29:1-11

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Gene Research/Therapy, Retina/Retinal Diseases

Retinal regeneration following OCT-guided laser injury in zebrafish.

DiCicco RM, Bell BA, Kaul C, Hollyfield JG, Anand-Apte B, Perkins BD, Tao YK, Yuan A

Invest Ophthalmol Vis Sci. 2014 Sep 9;55(10):6281-8

Cleveland Clinic Lerner College of Medicine - Stein Professorship - Perkins, Brian / PhD Departmental Grant

Keywords: Imaging, Stem Cell Research/Therapy

August, 2014
BAC-EDTA transepithelial riboflavin-UVA crosslinking has greater biomechanical stiffening effect than standard epithelium-off in rabbit corneas.

Torricelli AA, Ford MR, Singh V, Santhiago MR, Dupps WJ,Jr, Wilson SE

Exp Eye Res. 2014 Aug;125:114-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Endothelial PAS domain-containing protein 1 (EPAS1) gene polymorphisms and response to anti-VEGF therapy in the comparison of AMD treatments trials (CATT).

Hagstrom SA, Ying GS, Pauer GJ, Huang J, Maguire MG, Martin DF, CATT Research Group

Ophthalmology. 2014 Aug;121(8):1663,4.e1

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Gene Research/Therapy

Nystagmus and related fixation instabilities following extraction of unilateral infantile cataract in the infant aphakia treatment study (IATS).

Felius J, Busettini C, Lynn MJ, Hartmann EE, Lambert SR, Infant Aphakia Treatment Study Group

Invest Ophthalmol Vis Sci. 2014 Aug 5;55(8):5332-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cataract

Simultaneous bilateral endophthalmitis after immediate sequential bilateral cataract surgery: What's the risk of functional blindness?

Schachat AP

Am J Ophthalmol. 2014 Aug;158(2):410-1

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cataract

The par-PrkC polarity complex is required for cilia growth in zebrafish photoreceptors.

Krock BL, Perkins BD

PLoS One. 2014 Aug 21;9(8):e104661

Cleveland Clinic Lerner College of Medicine - Stein Professorship - Perkins, Brian / PhD Departmental Grant

Keyword: Other: Retinal Cell Biology

Topical cyclosporine a treatment in corneal refractive surgery and patients with dry eye.

Torricelli AA, Santhiago MR, Wilson SE

J Refract Surg. 2014 Aug;30(8):558-64

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

July, 2014
Optical coherence tomography imaging of macular oedema.

Trichonas G, Kaiser PK

Br J Ophthalmol. 2014 Jul;98 Suppl 2:ii24-9

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Optical Coherence Tomography

Utility of intraoperative optical coherence tomography during vitrectomy surgery for vitreomacular traction syndrome.

Ehlers JP, Tam T, Kaiser PK, Martin DF, Smith GM, Srivastava SK

Retina. 2014 Jul;34(7):1341-6

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Optical Coherence Tomography

June, 2014
Biomechanics of corneal ectasia and biomechanical treatments.

Roberts CJ, Dupps WJ,Jr

J Cataract Refract Surg. 2014 Jun;40(6):991-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Comparison of biomechanical effects of small-incision lenticule extraction and laser in situ keratomileusis: Finite-element analysis.

Sinha Roy A, Dupps WJ,Jr, Roberts CJ

J Cataract Refract Surg. 2014 Jun;40(6):971-80

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Comparison of contact lens and intraocular lens correction of monocular aphakia during infancy: A randomized clinical trial of HOTV optotype acuity at age 4.5 years and clinical findings at age 5 years.

Infant Aphakia Treatment Study Group, Lambert SR, Lynn MJ, Hartmann EE, DuBois L, Drews-Botsch C, Freedman SF, Plager DA, Buckley EG, Wilson ME

JAMA Ophthalmol. 2014 Jun;132(6):676-82

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Pediatric

Inducing a visceral organ to protect a peripheral capillary bed: Stabilizing hepatic HIF-1alpha prevents oxygen-induced retinopathy.

Hoppe G, Lee TJ, Yoon S, Yu M, Peachey NS, Rayborn M, Zutel MJ, Trichonas G, Au J, Sears JE

Am J Pathol. 2014 Jun;184(6):1890-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Introduction.

Singh RP

treatment paradigms within the use of anti-VEGF agents. Br J Ophthalmol. 2014 Jun;98 Suppl 1:i1-2

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Pathology detection rate of spectral domain optical coherence tomography devices.

Sharma S, Sayanagi K, Kaiser PK

Br J Ophthalmol. 2014 Jun;98 Suppl 1:i3-6

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Retina/Retinal Diseases

Patterned corneal collagen crosslinking for astigmatism: Computational modeling study.

Seven I, Sinha Roy A, Dupps WJ,Jr

J Cataract Refract Surg. 2014 Jun;40(6):943-53

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Retinoschisis and hyperopia associated with partial monosomy of 6q and partial trisomy of 11q.

Bagheri N, Bahl RS, Singh AD, Rychwalski PJ

Ophthalmic Genet. 2014 Jun;35(2):107-11

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Pediatric

Serial biomechanical comparison of edematous, normal, and collagen crosslinked human donor corneas using optical coherence elastography.

Ford MR, Sinha Roy A, Rollins AM, Dupps WJ,Jr

J Cataract Refract Surg. 2014 Jun;40(6):1041-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

The role of preoperative biometry in selecting initial contact lens power in the infant aphakia treatment study.

Trivedi RH, Lambert SR, Lynn MJ, Wilson ME, Infant Aphakia Treatment Study Group

J AAPOS. 2014 Jun;18(3):251-4

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Toric topographically customized transepithelial, pulsed, very high-fluence, higher energy and higher riboflavin concentration collagen cross-linking in keratoconus.

Kanellopoulos AJ, Dupps WJ, Seven I, Asimellis G

Case Rep Ophthalmol. 2014 Jun 18;5(2):172-80

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

May, 2014
The proteomics of drusen.

Crabb JW

Cold Spring Harb Perspect Med. 2014 May 5;4(7):a017194

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

VEGFA and VEGFR2 gene polymorphisms and response to anti-vascular endothelial growth factor therapy: Comparison of age-related macular degeneration treatments trials (CATT).

Hagstrom SA, Ying GS, Pauer GJ, Sturgill-Short GM, Huang J, Maguire MG, Martin DF, Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Research Group

JAMA Ophthalmol. 2014 May;132(5):521-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Gene Research/Therapy

April, 2014
Circulating immune cell and microRNA in patients with uveal melanoma developing metastatic disease.

Achberger S, Aldrich W, Tubbs R, Crabb JW, Singh AD, Triozzi PL

Mol Immunol. 2014 Apr;58(2):182-6

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Ocular Oncology/Pterygium, Other: Biomarkers

GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.

Ray TA, Heath KM, Hasan N, Noel JM, Samuels IS, Martemyanov KA, Peachey NS, McCall MA, Gregg RG

J Neurosci. 2014 Apr 30;34(18):6334-43

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Mouse b-wave mutants.

Pardue MT, Peachey NS

Doc Ophthalmol. 2014 Apr;128(2):77-89

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Predictors of visual acuity and genotype-phenotype correlates in a cohort of patients with stargardt disease.

Miraldi Utz V, Coussa RG, Marino MJ, Chappelow AV, Pauer GJ, Hagstrom SA, Traboulsi EI

Br J Ophthalmol. 2014 Apr;98(4):513-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Gene Research/Therapy, Pediatric

Source of high-frequency oscillations in oblique saccade trajectory.

Ghasia FF, Shaikh AG

Exp Eye Res. 2014 Apr;121:5-10

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Neuro-Ophthalmology

TGFbeta and PDGF-B signaling blockade inhibits myofibroblast development from both bone marrow-derived and keratocyte-derived precursor cells in vivo.

Singh V, Jaini R, Torricelli AA, Santhiago MR, Singh N, Ambati BK, Wilson SE

Exp Eye Res. 2014 Apr;121:35-40

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Viewing condition dependence of the gaze-evoked nystagmus in arnold chiari type 1 malformation.

Ghasia FF, Gulati D, Westbrook EL, Shaikh AG

J Neurol Sci. 2014 Apr 15;339(1-2):134-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Neuro-Ophthalmology

March, 2014
Anatomical and visual outcomes following ocriplasmin treatment for symptomatic vitreomacular traction syndrome.

Singh RP, Li A, Bedi R, Srivastava S, Sears JE, Ehlers JP, Schachat AP, Kaiser PK

Br J Ophthalmol. 2014 Mar;98(3):356-60

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Retina/Retinal Diseases

Emerging treatments for wet age-related macular degeneration.

Smith AG, Kaiser PK

Expert Opin Emerg Drugs. 2014 Mar;19(1):157-64

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: AMD

Glucocorticoids: Structure, signaling and molecular mechanisms in the treatment of diabetic retinopathy and diabetic macular edema.

Zhang X, Wang N, Schachat AP, Bao S, Gillies MC

Curr Mol Med. 2014 Mar;14(3):376-84

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Diabetic Retinopathy

Risk of scar in the comparison of age-related macular degeneration treatments trials.

Daniel E, Toth CA, Grunwald JE, Jaffe GJ, Martin DF, Fine SL, Huang J, Ying GS, Hagstrom SA, Winter K, Maguire MG, Comparison of Age-related Macular Degeneration Treatments Trials Research Group

Ophthalmology. 2014 Mar;121(3):656-66

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

The impact of metabolic parameters on clinical response to VEGF inhibitors for diabetic macular edema.

Matsuda S, Tam T, Singh RP, Kaiser PK, Petkovsek D, Carneiro G, Zanella MT, Ehlers JP

J Diabetes Complications. 2014 Mar-Apr;28(2):166-70

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Diabetic Retinopathy

Transforming growth factor beta and platelet-derived growth factor modulation of myofibroblast development from corneal fibroblasts in vitro.

Singh V, Barbosa FL, Torricelli AA, Santhiago MR, Wilson SE

Exp Eye Res. 2014 Mar;120:152-60

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

February, 2014
Comparison of intravitreal ranibizumab and bevacizumab for the treatment of macular edema secondary to retinal vein occlusion.

Yuan A, Ahmad BU, Xu D, Singh RP, Kaiser PK, Martin DF, Sears JE, Schachat AP, Ehlers JP

Int J Ophthalmol. 2014 Feb 18;7(1):86-91

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Imaging, Retinal Vein and Artery Occlusion

Differential loss of prolyl isomerase or chaperone activity of ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

Cho KI, Patil H, Senda E, Wang J, Yi H, Qiu S, Yoon D, Yu M, Orry A, Peachey NS, Ferreira PA

J Biol Chem. 2014 Feb 21;289(8):4600-25

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Discriminant value of custom ocular response analyzer waveform derivatives in keratoconus.

Hallahan KM, Sinha Roy A, Ambrosio R,Jr, Salomao M, Dupps WJ,Jr

Ophthalmology. 2014 Feb;121(2):459-68

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Intrasurgical dynamics of macular hole surgery: An assessment of surgery-induced ultrastructural alterations with intraoperative optical coherence tomography.

Ehlers JP, Xu D, Kaiser PK, Singh RP, Srivastava SK

Retina. 2014 Feb;34(2):213-21

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Optical Coherence Tomography

January, 2014
Risk of geographic atrophy in the comparison of age-related macular degeneration treatments trials.

Grunwald JE, Daniel E, Huang J, Ying GS, Maguire MG, Toth CA, Jaffe GJ, Fine SL, Blodi B, Klein ML, Martin AA, Hagstrom SA, Martin DF, CATT Research Group

Ophthalmology. 2014 Jan;121(1):150-61

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

Wound construction.

Trichonas G, Kaiser PK

Dev Ophthalmol. 2014;54:71-6

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Retina/Retinal Diseases

December, 2013
Autosomal dominant retinitis pigmentosa secondary to pre-mRNA splicing-factor gene PRPF31 (RP11): Review of disease mechanism and report of a family with a novel 3-base pair insertion.

Utz VM, Beight CD, Marino MJ, Hagstrom SA, Traboulsi EI

Ophthalmic Genet. 2013 Dec;34(4):183-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

Identification of three ABCA4 sequence variations exclusive to african american patients in a cohort of patients with stargardt disease.

Utz VM, Chappelow AV, Marino MJ, Beight CD, Sturgill-Short GM, Pauer GJ, Crowe S, Hagstrom SA, Traboulsi EI

Am J Ophthalmol. 2013 Dec;156(6):122-7.e2

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Gene Research/Therapy

November, 2013
A method to generate enhanced GFP+ chimeric mice to study the role of bone marrow-derived cells in the eye.

Singh V, Jaini R, Torricelli AA, Tuohy VK, Wilson SE

Exp Eye Res. 2013 Nov;116:366-70

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Myosin 6 is required for iris development and normal function of the outer retina.

Samuels IS, Bell BA, Sturgill-Short G, Ebke LA, Rayborn M, Shi L, Nishina PM, Peachey NS

Invest Ophthalmol Vis Sci. 2013 Nov 1;54(12):7223-33

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Iris

October, 2013
CEP biomarkers as potential tools for monitoring therapeutics.

Renganathan K, Gu J, Rayborn ME, Crabb JS, Salomon RG, Collier RJ, Kapin MA, Romano C, Hollyfield JG, Crabb JW

PLoS One. 2013 Oct 1;8(10):e76325

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases, Other: Biomarkers

Comprehensive molecular diagnosis of 179 leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing.

Wang X, Wang H, Sun V, Tuan HF, Keser V, Wang K, Ren H, Lopez I, Zaneveld JE, Siddiqui S, Bowles S, Khan A, Salvo J, Jacobson SG, Iannaccone A, Wang F, Birch D, Heckenlively JR, Fishman GA, Traboulsi EI, Li Y, Wheaton D, Koenekoop RK, Chen R

J Med Genet. 2013 Oct;50(10):674-88

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Gene Research/Therapy, Retinitis Pigmentosa

Mouse strain variation in SMA(+) myofibroblast development after corneal injury.

Singh V, Torricelli AA, Nayeb-Hashemi N, Agrawal V, Wilson SE

Exp Eye Res. 2013 Oct;115:27-30

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Ultrastructural localization of GPR179 and the impact of mutant forms on retinal function in CSNB1 patients and a mouse model.

Klooster J, van Genderen MM, Yu M, Florijn RJ, Riemslag FC, Bergen AA, Gregg RG, Peachey NS, Kamermans M

Invest Ophthalmol Vis Sci. 2013 Oct 23;54(10):6973-81

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Retina/Retinal Diseases, Other: Congenital Stationary Night Blindness

September, 2013
A young woman with proptosis.

Pabon S, Emch T, Lee J, Singh AD

Br J Ophthalmol. 2013 Sep;97(9):1213, 1222

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Ocular Oncology/Pterygium

Inhibition of EGF signaling protects the diabetic retina from insulin-induced vascular leakage.

Sugimoto M, Cutler A, Shen B, Moss SE, Iyengar SK, Klein R, Folkman J, Anand-Apte B

Am J Pathol. 2013 Sep;183(3):987-95

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Diabetic Retinopathy

Mutations in IMPG1 cause vitelliform macular dystrophies.

Manes G, Meunier I, Avila-Fernandez A, Banfi S, Le Meur G, Zanlonghi X, Corton M, Simonelli F, Brabet P, Labesse G, Audo I, Mohand-Said S, Zeitz C, Sahel JA, Weber M, Dollfus H, Dhaenens CM, Allorge D, De Baere E, Koenekoop RK, Kohl S, Cremers FP, Hollyfield JG, Senechal A, Hebrard M, Bocquet B, Ayuso Garcia C, Hamel CP

Am J Hum Genet. 2013 Sep 5;93(3):571-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Macular Dystrophy

Ocular adnexal lymphoma: Assessment of a tumor-node-metastasis staging system.

Aronow ME, Portell CA, Rybicki LA, Sweetenham JW, Singh AD

Ophthalmology. 2013 Sep;120(9):1915-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Ocular Oncology/Pterygium

The corneal epithelial basement membrane: Structure, function, and disease.

Torricelli AA, Singh V, Santhiago MR, Wilson SE

Invest Ophthalmol Vis Sci. 2013 Sep 27;54(9):6390-400

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

August, 2013
Association of smoking and other risk factors with fuchs' endothelial corneal dystrophy severity and corneal thickness.

Zhang X, Igo RP,Jr, Fondran J, Mootha VV, Oliva M, Hammersmith K, Sugar A, Lass JH, Iyengar SK, Fuchs' Genetics Multi-Center Study Group

Invest Ophthalmol Vis Sci. 2013 Aug 27;54(8):5829-35

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Evolutionarily conserved long intergenic non-coding RNAs in the eye.

Mustafi D, Kevany BM, Bai X, Maeda T, Sears JE, Khalil AM, Palczewski K

Hum Mol Genet. 2013 Aug 1;22(15):2992-3002

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Gene Research/Therapy

Inverse computational analysis of in vivo corneal elastic modulus change after collagen crosslinking for keratoconus.

Sinha Roy A, Rocha KM, Randleman JB, Stulting RD, Dupps WJ,Jr

Exp Eye Res. 2013 Aug;113:92-104

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Long-term effects of vitamins C and E, beta-carotene, and zinc on age-related macular degeneration: AREDS report no. 35.

Chew EY, Clemons TE, Agron E, Sperduto RD, Sangiovanni JP, Kurinij N, Davis MD, Age-Related Eye Disease Study Research Group

Ophthalmology. 2013 Aug;120(8):1604,11.e4

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

Special section on collagen crosslinking: New hope for more advanced ectatic disease?

Dupps WJ,Jr

J Cataract Refract Surg. 2013 Aug;39(8):1131-2

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

July, 2013
DJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE).

Shadrach KG, Rayborn ME, Hollyfield JG, Bonilha VL

PLoS One. 2013 Jul 2;8(7):e67983

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Novel microarchitectural dynamics in rhegmatogenous retinal detachments identified with intraoperative optical coherence tomography.

Ehlers JP, Ohr MP, Kaiser PK, Srivastava SK

Retina. 2013 Jul-Aug;33(7):1428-34

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Retina/Retinal Diseases

Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy in the rat 50/10 model.

Trichonas G, Lee TJ, Hoppe G, Au J, Sears JE

Invest Ophthalmol Vis Sci. 2013 Jul 22;54(7):4919-26

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Protein partners of dynamin-1 in the retina.

Grossman GH, Ebke LA, Beight CD, Jang GF, Crabb JW, Hagstrom SA

Vis Neurosci. 2013 Jul;30(4):129-39

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Gene Research/Therapy, Other: Proteomics

June, 2013
16 and 24 gy low-voltage X-ray irradiation with ranibizumab therapy for neovascular age-related macular degeneration: 12-month outcomes.

Morales-Canton V, Quiroz-Mercado H, Velez-Montoya R, Zavala-Ayala A, Moshfeghi AA, Shusterman EM, Kaiser PK, Sanislo SR, Gertner M, Moshfeghi DM

Am J Ophthalmol. 2013 Jun;155(6):1000-8.e2

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

Cho KI, Haque M, Wang J, Yu M, Hao Y, Qiu S, Pillai IC, Peachey NS, Ferreira PA

PLoS Genet. 2013 Jun;9(6):e1003555

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Retinal deimination and PAD2 levels in retinas from donors with age-related macular degeneration (AMD).

Bonilha VL, Shadrach KG, Rayborn ME, Li Y, Pauer GJ, Hagstrom SA, Bhattacharya SK, Hollyfield JG

Exp Eye Res. 2013 Jun;111:71-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

Trans-tamponade optical coherence tomography: Postoperative imaging in gas-filled eyes.

Ehlers JP, Yuan A, Kaiser PK, Dhoot D, Sears JE, Martin DF, Singh RP, Srivastava SK

Retina. 2013 Jun;33(6):1172-8

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Myopia/Presbyopia, Retina/Retinal Diseases

Transmission electron microscopy analysis of epithelial basement membrane repair in rabbit corneas with haze.

Torricelli AA, Singh V, Agrawal V, Santhiago MR, Wilson SE

Invest Ophthalmol Vis Sci. 2013 Jun 10;54(6):4026-33

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

May, 2013
Biological and biomechanical responses to traditional epithelium-off and transepithelial riboflavin-UVA CXL techniques in rabbits.

Armstrong BK, Lin MP, Ford MR, Santhiago MR, Singh V, Grossman GH, Agrawal V, Roy AS, Butler RS, Dupps WJ, Wilson SE

J Refract Surg. 2013 May;29(5):332-41

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Combination therapy for the treatment of neovascular age-related macular degeneration.

Englander M, Kaiser PK

Curr Opin Ophthalmol. 2013 May;24(3):233-8

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: AMD

April, 2013
Clinical classification of age-related macular degeneration.

Ferris FL,3rd, Wilkinson CP, Bird A, Chakravarthy U, Chew E, Csaky K, Sadda SR, Beckman Initiative for Macular Research Classification Committee

Ophthalmology. 2013 Apr;120(4):844-51

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

Early treatment response of fluocinolone (retisert) implantation in patients with uveitic macular edema: An optical coherence tomography study.

Shen BY, Punjabi OS, Lowder CY, Sears JE, Singh RP

Retina. 2013 Apr;33(4):873-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Uveitis/Infectious Diseases

Seven new loci associated with age-related macular degeneration.

Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP,Jr, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Mohand-Said S, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC, Nakamura Y, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Sahel JA, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, Uitterlinden AG, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Leveillard T, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, Abecasis GR, AMD Gene Consortium

Nat Genet. 2013 Apr;45(4):433-9.e1-2

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Gene Research/Therapy, Other: Congenital Stationary Night Blindness

March, 2013
Childhood retinal dystrophies: What's in a name?

Traboulsi EI

Br J Ophthalmol. 2013 Mar;97(3):247

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

February, 2013
Comparison of inferior oblique myectomy to recession for the treatment of superior oblique palsy.

Bahl RS, Marcotty A, Rychwalski PJ, Traboulsi EI

Br J Ophthalmol. 2013 Feb;97(2):184-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Pediatric

Ocular phototherapy.

Singh AD

Eye (Lond). 2013 Feb;27(2):190-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Ocular Oncology/Pterygium

Visual acuity changes in patients with leber congenital amaurosis and mutations in CEP290.

McAnany JJ, Genead MA, Walia S, Drack AV, Stone EM, Koenekoop RK, Traboulsi EI, Smith A, Weleber RG, Jacobson SG, Fishman GA

JAMA Ophthalmol. 2013 Feb;131(2):178-82

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Gene Research/Therapy

January, 2013
A novel segmentation algorithm for volumetric analysis of macular hole boundaries identified with optical coherence tomography.

Xu D, Yuan A, Kaiser PK, Srivastava SK, Singh RP, Sears JE, Martin DF, Ehlers JP

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):163-9

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Retina/Retinal Diseases

Evaluation of choroidal thickness in retinitis pigmentosa using enhanced depth imaging optical coherence tomography.

Dhoot DS, Huo S, Yuan A, Xu D, Srivistava S, Ehlers JP, Traboulsi E, Kaiser PK

Br J Ophthalmol. 2013 Jan;97(1):66-9

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Retina/Retinal Diseases

Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration.

Cruz-Guilloty F, Saeed AM, Echegaray JJ, Duffort S, Ballmick A, Tan Y, Betancourt M, Viteri E, Ramkhellawan GC, Ewald E, Feuer W, Huang D, Wen R, Hong L, Wang H, Laird JM, Sene A, Apte RS, Salomon RG, Hollyfield JG, Perez VL

Int J Inflam. 2013;2013:503725

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

Intravitreal injection of TIMP3 or the EGFR inhibitor erlotinib offers protection from oxygen-induced retinopathy in mice.

Hewing NJ, Weskamp G, Vermaat J, Farage E, Glomski K, Swendeman S, Chan RV, Chiang MF, Khokha R, Anand-Apte B, Blobel CP

Invest Ophthalmol Vis Sci. 2013 Jan 30;54(1):864-70

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Tissue inhibitor of metalloproteinases-3 peptides inhibit angiogenesis and choroidal neovascularization in mice.

Qi JH, Ebrahem Q, Ali M, Cutler A, Bell B, Prayson N, Sears J, Knauper V, Murphy G, Anand-Apte B

PLoS One. 2013;8(3):e55667

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Macular Dystrophy

December, 2012
Dosimetric benefit of a new ophthalmic radiation plaque.

Marwaha G, Wilkinson A, Bena J, Macklis R, Singh AD

Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):1226-30

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Ocular Oncology/Pterygium

Evaluation of fluocinolone acetonide sustained release implant (retisert) dissociation during implant removal and exchange surgery.

Nicholson BP, Singh RP, Sears JE, Lowder CY, Kaiser PK

Am J Ophthalmol. 2012 Dec;154(6):969-73.e1

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keyword: Retina/Retinal Diseases

Ocular manifestations of the autoinflammatory syndromes.

Tarabishy AB, Hise AG, Traboulsi EI

Ophthalmic Genet. 2012 Dec;33(4):179-86

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Uveitis/Infectious Diseases, Other: Inflammation

Response properties of slow PIII in the large vls mutant.

Peachey N, Sturgill-Short G

Documenta Ophthalmologica. 2012 Dec;125(3):203-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

November, 2012
A novel role of complement in retinal degeneration.

Yu M, Zou W, Peachey NS, McIntyre TM, Liu J

Invest Ophthalmol Vis Sci. 2012 Nov 19;53(12):7684-92

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Retinitis Pigmentosa, Other: Photoreceptor, Retinal Pigment Epithelium

Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.

Peachey NS, Pearring JN, Bojang P,Jr, Hirschtritt ME, Sturgill-Short G, Ray TA, Furukawa T, Koike C, Goldberg AF, Shen Y, McCall MA, Nawy S, Nishina PM, Gregg RG

J Neurophysiol. 2012 Nov;108(9):2442-51

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Gene Research/Therapy, Retina/Retinal Diseases

Exclusion of aldose reductase as a mediator of ERG deficits in a mouse model of diabetic eye disease.

Samuels IS, Lee CA, Petrash JM, Peachey NS, Kern TS

Vis Neurosci. 2012 Nov;29(6):267-74

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Diabetic Retinopathy

Paraneoplastic vitelliform retinopathy: Clinicopathologic correlation and review of the literature.

Aronow ME, Adamus G, Abu-Asab M, Wang Y, Chan CC, Zakov ZN, Singh AD

Surv Ophthalmol. 2012 Nov;57(6):558-64

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Ocular Oncology/Pterygium

October, 2012
16 gy low-voltage x-ray irradiation followed by as needed ranibizumab therapy for age-related macular degeneration: 12 month outcomes of a 'radiation-first' strategy.

Moshfeghi AA, Morales-Canton V, Quiroz-Mercado H, Velez-Montoya R, Zavala-Ayala A, Shusterman EM, Kaiser PK, Sanislo SR, Gertner M, Moshfeghi DM

Br J Ophthalmol. 2012 Oct;96(10):1320-4

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: AMD, Diabetic Retinopathy

September, 2012
Diagnostic and therapeutic challenges.

Agarwal A, Colburn JD, Raja H, Singh AD

Retina. 2012 Sep;32(8):1678-81

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Ocular Oncology/Pterygium

Monosomy 3 by FISH in uveal melanoma: Variability in techniques and results.

Aronow M, Sun Y, Saunthararajah Y, Biscotti C, Tubbs R, Triozzi P, Singh AD

Surv Ophthalmol. 2012 Sep;57(5):463-73

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Ocular Oncology/Pterygium

Tuberous sclerosis complex: Genotype/phenotype correlation of retinal findings.

Aronow ME, Nakagawa JA, Gupta A, Traboulsi EI, Singh AD

Ophthalmology. 2012 Sep;119(9):1917-23

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Gene Research/Therapy, Pediatric, Retina/Retinal Diseases

August, 2012
Abnormal vascularization in mouse retina with dysregulated retinal cholesterol homeostasis.

Omarova S, Charvet CD, Reem RE, Mast N, Zheng W, Huang S, Peachey NS, Pikuleva IA

J Clin Invest. 2012 Aug 1;122(8):3012-23

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

Aflibercept for age-related macular degeneration: A game-changer or quiet addition?

Browning DJ, Kaiser PK, Rosenfeld PJ, Stewart MW

Am J Ophthalmol. 2012 Aug;154(2):222-6

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

July, 2012
The infant aphakia treatment study contact lens experience: One-year outcomes.

Russell B, Ward MA, Lynn M, Dubois L, Lambert SR, Infant Aphakia Treatment Study Group

Eye Contact Lens. 2012 Jul;38(4):234-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Pediatric, Other: Lens

June, 2012
Acute episode of eyelid oedema.

Hallahan KM, Sood A, Singh AD

blepharochalasis. Br J Ophthalmol. 2012 Jun;96(6):909-13

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Chromosome 3 status in uveal melanoma: A comparison of fluorescence in situ hybridization and single-nucleotide polymorphism array.

Singh AD, Aronow ME, Sun Y, Bebek G, Saunthararajah Y, Schoenfield LR, Biscotti CV, Tubbs RR, Triozzi PL, Eng C

Invest Ophthalmol Vis Sci. 2012 Jun 5;53(7):3331-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Ocular Oncology/Pterygium

Corneal myofibroblast biology and pathobiology: Generation, persistence, and transparency.

Wilson SE

Exp Eye Res. 2012 Jun;99:78-88

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

May, 2012
Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.

Matsuoka RL, Jiang Z, Samuels IS, Nguyen-Ba-Charvet KT, Sun LO, Peachey NS, Chedotal A, Yau KW, Kolodkin AL

J Neurosci. 2012 May 16;32(20):6859-68

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

Stromal fibroblast-bone marrow-derived cell interactions: Implications for myofibroblast development in the cornea.

Singh V, Agrawal V, Santhiago MR, Wilson SE

Exp Eye Res. 2012 May;98:1-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

April, 2012
Altered angiogenesis in caveolin-1 gene-deficient mice is restored by ablation of endothelial nitric oxide synthase.

Morais C, Ebrahem Q, Anand-Apte B, Parat MO

Am J Pathol. 2012 Apr;180(4):1702-14

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Diabetic Retinopathy

Collagenase-mediated tissue modeling of corneal ectasia and collagen cross-linking treatments.

Hong CW, Sinha-Roy A, Schoenfield L, McMahon JT, Dupps WJ,Jr

Invest Ophthalmol Vis Sci. 2012 Apr 30;53(4):2321-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Other: Collagen Crosslinking

Predictors of adherence to occlusion therapy 3 months after cataract extraction in the infant aphakia treatment study.

Drews-Botsch CD, Hartmann EE, Celano M, Infant Aphakia Treatment Study Group

J AAPOS. 2012 Apr;16(2):150-5

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Pediatric, Other: Lens

Relationship of fuchs endothelial corneal dystrophy severity to central corneal thickness.

Kopplin LJ, Przepyszny K, Schmotzer B, Rudo K, Babineau DC, Patel SV, Verdier DD, Jurkunas U, Iyengar SK, Lass JH, Fuchs' Endothelial Corneal Dystrophy Genetics Multi-Center Study Group

Arch Ophthalmol. 2012 Apr;130(4):433-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Gene Research/Therapy, Glaucoma

March, 2012
Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia.

Yu M, Sturgill-Short G, Ganapathy P, Tawfik A, Peachey NS, Smith SB

Exp Eye Res. 2012 Mar;96(1):124-31

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Retinitis Pigmentosa, Other: Photoreceptor, Other: Retinal Pigment Epithelium

Interleukin-1 receptor role in the viability of corneal myofibroblasts.

Barbosa FL, Lin M, Santhiago MR, Singh V, Agrawal V, Wilson SE

Exp Eye Res. 2012 Mar;96(1):65-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Other: Stroma, Other: Wound Healing

Mitomycin C: Biological effects and use in refractive surgery.

Santhiago MR, Netto MV, Wilson SE

Cornea. 2012 Mar;31(3):311-21

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Other: Mitomycin C, Wound Healing

Ranibizumab for age-related macular degeneration.

Dhoot DS, Kaiser PK

Expert Opin Biol Ther. 2012 Mar;12(3):371-81

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

February, 2012
Cellular effects after laser in situ keratomileusis flap formation with femtosecond lasers: A review.

Santhiago MR, Wilson SE

Cornea. 2012 Feb;31(2):198-205

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Other: LASIK

GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness.

Peachey NS, Ray TA, Florijn R, Rowe LB, Sjoerdsma T, Contreras-Alcantara S, Baba K, Tosini G, Pozdeyev N, Iuvone PM, Bojang P,Jr, Pearring JN, Simonsz HJ, van Genderen M, Birch DG, Traboulsi EI, Dorfman A, Lopez I, Ren H, Goldberg AF, Nishina PM, Lachapelle P, McCall MA, Koenekoop RK, Bergen AA, Kamermans M, Gregg RG

Am J Hum Genet. 2012 Feb 10;90(2):331-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Gene Research/Therapy, Retina/Retinal Diseases

Short-term cell death and inflammation after intracorneal inlay implantation in rabbits.

Santhiago MR, Barbosa FL, Agrawal V, Binder PS, Christie B, Wilson SE

J Refract Surg. 2012 Feb;28(2):144-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

January, 2012
ADAMTSL4, a secreted glycoprotein widely distributed in the eye, binds fibrillin-1 microfibrils and accelerates microfibril biogenesis.

Gabriel LA, Wang LW, Bader H, Ho JC, Majors AK, Hollyfield JG, Traboulsi EI, Apte SS

Invest Ophthalmol Vis Sci. 2012 Jan 31;53(1):461-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Other: Lens, Other: Zonule

Age-related changes in the retinal pigment epithelium (RPE).

Gu X, Neric NJ, Crabb JS, Crabb JW, Bhattacharya SK, Rayborn ME, Hollyfield JG, Bonilha VL

PLoS One. 2012;7(6):e38673

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Other: Aging

A multicenter study to map genes for fuchs endothelial corneal dystrophy: Baseline characteristics and heritability.

Louttit MD, Kopplin LJ, Igo RP,Jr, Fondran JR, Tagliaferri A, Bardenstein D, Aldave AJ, Croasdale CR, Price MO, Rosenwasser GO, Lass JH, Iyengar SK, FECD Genetics Multi-Center Study Group

Cornea. 2012 Jan;31(1):26-35

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Gene Research/Therapy

Flaporhexis: Rapid and effective technique to limit epithelial ingrowth after LASIK enhancement.

Wilson SE, Santhiago MR

J Cataract Refract Surg. 2012 Jan;38(1):2-4

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Other: LASIK

Panretinal photocoagulation for proliferative diabetic retinopathy: Pattern scan laser versus argon laser.

Chappelow AV, Tan K, Waheed NK, Kaiser PK

Am J Ophthalmol. 2012 Jan;153(1):137-42.e2

Cleveland Clinic Lerner College of Medicine - Lew R. Wasserman Merit Award - Kaiser, Peter Kazuo / MD Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

Proteomic similarities in steroid responsiveness in normal and glaucomatous trabecular meshwork cells.

Bollinger KE, Crabb JS, Yuan X, Putliwala T, Clark AF, Crabb JW

Mol Vis. 2012;18:2001-11

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Glaucoma, Other: Proteomics

December, 2011
Effect of TGFbeta and PDGF-B blockade on corneal myofibroblast development in mice.

Singh V, Santhiago MR, Barbosa FL, Agrawal V, Singh N, Ambati BK, Wilson SE

Exp Eye Res. 2011 Dec;93(6):810-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

November, 2011
Discovery of carboxyethylpyrroles (CEPs): Critical insights into AMD, autism, cancer, and wound healing from basic research on the chemistry of oxidized phospholipids.

Salomon RG, Hong L, Hollyfield JG

Chem Res Toxicol. 2011 Nov 21;24(11):1803-16

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Retina/Retinal Diseases

Immunocytochemical evidence of Tulp1-dependent outer segment protein transport pathways in photoreceptor cells.

Grossman GH, Watson RF, Pauer GJ, Bollinger K, Hagstrom SA

Exp Eye Res. 2011 Nov;93(5):658-68

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Other: Photoreceptor, Other: Retinal Degeneration

Monocyte development inhibitor PRM-151 decreases corneal myofibroblast generation in rabbits.

Santhiago MR, Singh V, Barbosa FL, Agrawal V, Wilson SE

Exp Eye Res. 2011 Nov;93(5):786-9

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Patient-specific computational modeling of keratoconus progression and differential responses to collagen cross-linking.

Sinha Roy A, Dupps WJ,Jr

Invest Ophthalmol Vis Sci. 2011 Nov 25;52(12):9174-87

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

October, 2011
Histopathology and functional correlations in a patient with a mutation in RPE65, the gene for retinol isomerase.

Bonilha VL, Rayborn ME, Li Y, Grossman GH, Berson EL, Hollyfield JG

Invest Ophthalmol Vis Sci. 2011 Oct 28;52(11):8381-92

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Genetics, Other: Histology, Other: Immunocytochemistry, Other: Retinal Degenerations

Quantitativeproteomics: TGFbeta signaling in trabecular meshwork cells.

Bollinger KE, Crabb JS, Yuan X, Putliwala T, Clark AF, Crabb JW

Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8287-94

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Glaucoma, Other: Proteomics

September, 2011
Distribution of voltage gated calcium channel beta subunits in the mouse retina.

Ball SL, McEnery MW, Yunker AM, Shin HS, Gregg RG

Brain Res. 2011 Sep 15;1412:1-8

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Neuro-Ophthalmology, Optic Neuropathy

August, 2011
Increased neovascularization in mice lacking tissue inhibitor of metalloproteinases-3.

Ebrahem Q, Qi JH, Sugimoto M, Ali M, Sears JE, Cutler A, Khokha R, Vasanji A, Anand-Apte B

Invest Ophthalmol Vis Sci. 2011 Aug 3;52(9):6117-23

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Macular Dystrophy, Retina/Retinal Diseases

March, 2011
Autoantibodies in melanoma-associated retinopathy target TRPM1 cation channels of retinal ON bipolar cells.

Dhingra A, Fina ME, Neinstein A, Ramsey DJ, Xu Y, Fishman GA, Alexander KR, Qian H, Peachey NS, Gregg RG, Vardi N

J Neurosci. 2011 Mar 16;31(11):3962-7

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Neuro-Ophthalmology, Ocular Oncology Melanoma

February, 2011
Visual abnormalities associated with enhanced optic nerve myelination.

Yu M, Narayanan SP, Wang F, Morse E, Macklin WB, Peachey NS

Brain Res. 2011 Feb 16;1374:36-42

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Neuro-Ophthalmology, Optic Neuropathy

January, 2011
Biomechanical corneal changes induced by different flap thickness created by femtosecond laser.

Medeiros FW, Sinha-Roy A, Alves MR, Dupps WJ,Jr

Clinics (Sao Paulo). 2011;66(6):1067-71

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Other: LASIK

Method for optical coherence elastography of the cornea.

Ford MR, Dupps WJ,Jr, Rollins AM, Roy AS, Hu Z

J Biomed Opt. 2011 Jan-Feb;16(1):016005

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Patient-specific modeling of corneal refractive surgery outcomes and inverse estimation of elastic property changes.

Roy AS, Dupps WJ,Jr

J Biomech Eng. 2011 Jan;133(1):011002

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cornea, Other: LASIK

January, 2010
A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration.

Hollyfield JG, Perez VL, Salomon RG

Mol Neurobiol 2010;41(2-3):290-298

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: AMD

A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development.

Xie J, Farage E, Sugimoto M, Anand-Apte B

BMC Developmental Biology 2010;10:76

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

A randomized clinical trial comparing contact lens with intraocular lens correction of monocular aphakia during infancy: Grating acuity and adverse events at age 1 year.

The Infant Aphakia Treatment Study Group

Arch Ophthalmol 2010;128(7):810-818

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cataract, Pediatric, Other: Surgery

Betacellulin induces increased retinal vascular permeability in mice.

Anand-Apte B, Ebrahem Q, Cutler A, Farage E, Sugimoto M, Hollyfield J, Folkman J

PLoS ONE 2010;5(10):e13444

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

Corneal myofibroblast generation from bone marrow-derived cells.

Barbosa FL, Chaurasia SS, Cutler A, Asosingh K, Kaur H, de Medeiros FW, Agrawal V, Wilson SE

Exp Eye Res 2010;91(1):92-96

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo.

Ebrahem Q, Chaurasia SS, Vasanji A, Qi JH, Klenotic PA, Cutler A, Asosingh K, Erzurum S, Anand-Apte B

Am J Pathol 2010;176(1):496-503

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

Differences in the early biomechanical effects of hyperopic and myopic laser in situ keratomileusis.

de Mederios FW, Sinha Roy A, Alves MR, Wilson SE, Dupps Jr WJ

J Cataract Refract Surg 2010;36(6):947-953

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Duane syndrome in the setting of chromosomal duplications.

Smith SB, Traboulsi EI

Am J Ophthalmol 2010;150(6):932-938

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Genetics, Movement Disorders, Pediatric

Femtosecond laser in laser in situ keratomileusis.

Salomao MQ, Wilson SE

J Cataract Refract Surg 2010;36(6):1024-1032

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Genetic defects of GDF6 in the zebrafish out of sight mutant and in human eye developmental anomalies.

den Hollander AI, Biyanwila J, Kovach P, Bardakjian T, Traboulsi EI, Ragge NK, Schneider A, Malicki J

BMC Genetics 2010;11:102

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Genetics, Pediatric, Other: Ocular Malformations

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL; Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) Research Group, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BEk, Gotoh N, Yamashiro K, Ferris III F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Cortón M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, DeAngelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR and Swaroop A

Proc Natl Acad Sci USA 2010;107(16):7401-7406

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Genetics

Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration.

Kopplin LJ, Igo Jr RP, Wang Y, Sivakumaran TA, Hagstrom SA, Peachey NS, Francis PJ, Klein ML, SanGiovanni JP, Chew EY, Pauer GJT, Sturgill GM, Joshi T, Tian L, Xi Q, Henning AK, Lee KE, Klein R, Klein BEK, Iyengar SK

Genes Immun 2010;11(8):609-621

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Genetics

Impaired function of circulating CD34+ CD45- cells in patients with proliferative diabetic retinopathy.

Tan K, Lessieur E, Cutler A, Nerone P, Vasanj A, Asosingh K, Erzurum S, Anand-Apte B

Exp Eye Res 2010;91(2):229-237

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Diabetic Retinopathy, Retina/Retinal Diseases

Light-evoked responses of the retinal pigment epithelium: Changes accompanying photoreceptor loss in the mouse.

Samuels IS, Sturgill GM, Grossman GH, Rayborn ME, Hollyfield JG, Peachey NS

J Neurophysiol 2010;104(1):391-402

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Retina/Retinal Diseases, Retinitis Pigmentosa

Mutation of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice.

Budzynski E, Gross AK, McAlear SD, Peachey NS, Shukla M, He F, Edwards M, Won J, Hicks WL, Wensel TG, Naggert JK, Nishina P

J Biol Chem 2010;285(19):14521-14533

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Genetics, Retina/Retinal Diseases, Retinitis Pigmentosa

Mutation screen of β-crystallin genes in 274 patients with age-related macular degeneration.

Sturgill GM, Bala E, Yaniglos SS, Peachey NS, Hagstrom SA

Ophthalmic Genet 2010;31(3):129-134

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Genetics, Pediatric, Retina/Retinal Diseases

Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation.

Edwards MM, Mammadova-Bach E, Alpy F, Klein A, Hicks WL, Roux M, Simon-Assmann P, Smith RS, Orend G, Wu J, Peachey NS, Naggert JK, Lefebvre O, Nishina P

J Biol Chem 2010;285(10):7697-7711

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Genetics, Retina/Retinal Diseases

Photoreceptor degeneration, azoospermia, leukoencephalopathy, and abnormal RPE cell function in mice expressing an early stop mutation in CLCN2.

Edwards MM, de Evsikova CM, Collin GB, Gifford E, Wu J, Hicks WL, Whiting C, Varvel NH, Maphis N, Lamb BT, Naggert JK, Nishina PM, Peachey NS

Invest Ophthalmol Vis Sci 2010;51(6):3264-3272

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Genetics, Retina/Retinal Diseases, Retinitis Pigmentosa

Preliminary quantitative proteomic characterization of glaucomatous rat retinal ganglion cells.

Crabb JW, Yuan X, Dvoriantchikova G, Ivanov D, Crabb JS, Shestopalov VI

Exp Eye Res 2010;91(1):107-110

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Other: Experimental Glaucoma, Other: retinal ganglion cells, Other: Quantitative Proteomics

Protective effect of paraoxonase 1 gene variant GIn192Arg in age-related macular degeneration.

Pauer GJT, Sturgill GM, Peachey NS, Hagstrom SA and the Clinical Genomic and Proteomic AMD Study Group

Am J Ophthalmol 2010;149(3):513-522

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Genetics

Quantitative proteomics: Comparison of the macular bruch membrane/choroid complex from age-related macular degeneration and normal eyes.

Yuan X, Gu X, Crabb JS, Yue X, Shadrach K, Hollyfield JG, Crabb JW

Mol Cell Proteomics 2010;9(6):1031-1046

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: AMD, Other: Macular Bruch's Membrane/Choroid, Other: Quantitative Proteomics

Spondylometaphyseal dysplasia with cone-rod dystrophy.

Turell M, Morrison S, Traboulsi EI

Ophthalmic Genet 2010;31(1):12-17

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Pediatric, Retinitis Pigmentosa

Stromal interleukin-1 expression in the cornea after haze-associated injury.

Barbosa FL, Chaurasia SS, Kaur H, de Medeiros FW, Agrawal V, Wilson SE

Exp Eye Res 2010;91(3):456-461

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Cornea

Suppression of Ca2+ signaling in a mouse model of best disease.

Zhang Y, Stanton JB, Wu J, Yu K, Hartzell HC, Peachey NS, Marmorstein LY and Marmorstein AD

Hum Mol Genet 2010;19(6):1108-1118

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keyword: Retina/Retinal Diseases

The infant aphakia treatment study: Design and clinical measures at enrollment.

The Infant Aphakia Treatment Study Group

Arch Ophthalmol 2010;128(1):21-27

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Cataract, Pediatric, Other: Surgery

Use of mitomycin-C for phototherapeutic keratectomy and photorefractive keratectomy surgery.

Shah RA, Wilson SE

Curr Opin Ophthalmol 2010;21(4):269-273

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Other: Corneal Wound Healing, Other: cytokines, Other: Mitomycin C, Other: Femtosecond Laser

Verteporfin photodynamic therapy of six eyes with retinal capillary haemangioma.

Sachdeva R, Dadgostar H, Kaiser PK, Sears JE, Singh AD

Acta Ophthalmol 2010;88(8):e334-e340

Cleveland Clinic Lerner College of Medicine - Departmental Grant

Keywords: Other: Photodynamic Therapy, Other: Retinal Haemantioma, Other: Verteporfin, Other: von Hippel-Lindau Disease

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